- Synergistic protection against hyperoxia-induced lung injury by neutrophils blockade and EC-SOD overexpressionJae H Min
Department of Pediatrics, State University of New York, Downstate MedicalCenter, Brooklyn, New York, NY, USA
Respir Res 13:58. 2012....
- Extracellular superoxide dismutase overexpression can reverse the course of hypoxia-induced pulmonary hypertensionMohamed N Ahmed
Cohen Children s Medical Center, North Shore Long Island Jewish Health System, New Hyde Park, New York, United States of America
Mol Med 18:38-46. 2012..5), RV/S + LV (0.293 ± 0.012 versus 0.372 ± 0.014) and PVWT (12.51 ± 0.72 versus 18.98 ± 1.24). On the basis of these findings, we concluded that overexpression of EC-SOD prevents the development of PH and ameliorates established PH...
- The protective effect of overexpression of extracellular superoxide dismutase on nitric oxide bioavailability in the lung after exposure to hyperoxia stressMohamed N Ahmed
Division of Neonatal Perinatal Medicine, Schneider Children s Hospital and Center for Heart and Lung Research, The Feinstein Institute for Medical Research, North Shore Long Island Jewish Health System, Manhasset, New York, USA
Exp Lung Res 37:10-7. 2011..These results show that transient EC-SOD overexpression maintains NO bioavailability, which directly leads to maintenance of cGMP activity and reduction of NF-κB activation under oxidative stress...