Marco A Zarbin

Summary

Affiliation: New Jersey
Country: USA

Publications

  1. doi request reprint Pathway-based therapies for age-related macular degeneration: an integrated survey of emerging treatment alternatives
    Marco A Zarbin
    Institute of Ophthalmology and Visual Science, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, New Jersey 07103, USA
    Retina 30:1350-67. 2010
  2. ncbi request reprint Current concepts in the pathogenesis of age-related macular degeneration
    Marco A Zarbin
    Institute of Ophthalmology and Visual Science at the New Jersey Medical School, University of Medicine and Dentistry of New Jersey, 90 Bergen Street, Suite 6100, Newark, NJ 07103 2499, USA
    Arch Ophthalmol 122:598-614. 2004
  3. doi request reprint A method to enhance cell survival on Bruch's membrane in eyes affected by age and age-related macular degeneration
    Ilene K Sugino
    Institute of Ophthalmology and Visual Science, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, USA
    Invest Ophthalmol Vis Sci 52:9598-609. 2011
  4. pmc Retinal pigment epithelium resurfacing of aged submacular human Bruch's membrane
    Vamsi K Gullapalli
    Institute of Ophthalmology and Visual Science, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, New Jersey, USA
    Trans Am Ophthalmol Soc 102:123-37; discussion 137-8. 2004
  5. pmc Comparison of FRPE and human embryonic stem cell-derived RPE behavior on aged human Bruch's membrane
    Ilene K Sugino
    The Institute of Ophthalmology and Visual Science, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, 90 Bergen Street, Newark, NJ 07101, USA
    Invest Ophthalmol Vis Sci 52:4979-97. 2011
  6. ncbi request reprint Culture-induced increase in alpha integrin subunit expression in retinal pigment epithelium is important for improved resurfacing of aged human Bruch's membrane
    Vamsi K Gullapalli
    The Institute of Ophthalmology and Visual Science, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103, USA
    Exp Eye Res 86:189-200. 2008
  7. doi request reprint Characterization of conditioned media collected from aged versus young human eye cups
    Anton M Kolomeyer
    Institute of Ophthalmology and Visual Science, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, New Jersey 07101, USA
    Invest Ophthalmol Vis Sci 52:5963-72. 2011
  8. doi request reprint Characterization of conditioned media collected from cultured adult versus fetal retinal pigment epithelial cells
    Anton M Kolomeyer
    Institute of Ophthalmology and Visual Science, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, New Jersey 07101, USA
    Invest Ophthalmol Vis Sci 52:5973-86. 2011
  9. ncbi request reprint Cyclic AMP prevents retraction of axon terminals in photoreceptors prepared for transplantation: an in vitro study
    Mohamad A Khodair
    Department of Neurology and Neurosciences, University of Medicine and Dentistry of New Jersey UMDNJ New Jersey Medical School, 185 South Orange Avenue, Newark, NJ 07103, USA
    Invest Ophthalmol Vis Sci 46:967-73. 2005
  10. pmc Cell-deposited matrix improves retinal pigment epithelium survival on aged submacular human Bruch's membrane
    Ilene K Sugino
    The Institute of Ophthalmology and Visual Science, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey 07101 1709, USA
    Invest Ophthalmol Vis Sci 52:1345-58. 2011

Collaborators

Detail Information

Publications46

  1. doi request reprint Pathway-based therapies for age-related macular degeneration: an integrated survey of emerging treatment alternatives
    Marco A Zarbin
    Institute of Ophthalmology and Visual Science, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, New Jersey 07103, USA
    Retina 30:1350-67. 2010
    ..To review treatments under development for age-related macular degeneration (AMD) in the context of current knowledge of AMD pathogenesis...
  2. ncbi request reprint Current concepts in the pathogenesis of age-related macular degeneration
    Marco A Zarbin
    Institute of Ophthalmology and Visual Science at the New Jersey Medical School, University of Medicine and Dentistry of New Jersey, 90 Bergen Street, Suite 6100, Newark, NJ 07103 2499, USA
    Arch Ophthalmol 122:598-614. 2004
    ..To review and synthesize information concerning the pathogenesis of age-related macular degeneration (AMD)...
  3. doi request reprint A method to enhance cell survival on Bruch's membrane in eyes affected by age and age-related macular degeneration
    Ilene K Sugino
    Institute of Ophthalmology and Visual Science, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, USA
    Invest Ophthalmol Vis Sci 52:9598-609. 2011
    ..To determine whether conditioned medium (CM) derived from bovine corneal endothelial cells (BCECs) can support transplanted cells on aged and age-related macular degeneration (AMD) Bruch's membrane (BM)...
  4. pmc Retinal pigment epithelium resurfacing of aged submacular human Bruch's membrane
    Vamsi K Gullapalli
    Institute of Ophthalmology and Visual Science, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, New Jersey, USA
    Trans Am Ophthalmol Soc 102:123-37; discussion 137-8. 2004
    ..To determine whether cultured fetal human retinal pigment epithelium (RPE) cells can attach and differentiate on submacular Bruch's membrane from donors over age 55...
  5. pmc Comparison of FRPE and human embryonic stem cell-derived RPE behavior on aged human Bruch's membrane
    Ilene K Sugino
    The Institute of Ophthalmology and Visual Science, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, 90 Bergen Street, Newark, NJ 07101, USA
    Invest Ophthalmol Vis Sci 52:4979-97. 2011
    ..To compare RPE derived from human embryonic stem cells (hES-RPE) and fetal RPE (fRPE) behavior on human Bruch's membrane (BM) from aged and AMD donors...
  6. ncbi request reprint Culture-induced increase in alpha integrin subunit expression in retinal pigment epithelium is important for improved resurfacing of aged human Bruch's membrane
    Vamsi K Gullapalli
    The Institute of Ophthalmology and Visual Science, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103, USA
    Exp Eye Res 86:189-200. 2008
    ..Relative lack of these integrin subunits in uncultured adult RPE may be responsible for poor resurfacing of aged submacular human Bruch's membrane by these cells...
  7. doi request reprint Characterization of conditioned media collected from aged versus young human eye cups
    Anton M Kolomeyer
    Institute of Ophthalmology and Visual Science, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, New Jersey 07101, USA
    Invest Ophthalmol Vis Sci 52:5963-72. 2011
    ..To characterize secretion of in situ retinal pigment epithelium (RPE) from healthy, aged adult, age-related macular degeneration (AMD) adult, and fetal donor eyes and to assess the impact on retinal survival in vitro...
  8. doi request reprint Characterization of conditioned media collected from cultured adult versus fetal retinal pigment epithelial cells
    Anton M Kolomeyer
    Institute of Ophthalmology and Visual Science, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, New Jersey 07101, USA
    Invest Ophthalmol Vis Sci 52:5973-86. 2011
    ..To characterize trophic factor secretion of cultured adult and fetal retinal pigment epithelial (RPE) cells and to assess the impact on porcine retinal survival in vitro...
  9. ncbi request reprint Cyclic AMP prevents retraction of axon terminals in photoreceptors prepared for transplantation: an in vitro study
    Mohamad A Khodair
    Department of Neurology and Neurosciences, University of Medicine and Dentistry of New Jersey UMDNJ New Jersey Medical School, 185 South Orange Avenue, Newark, NJ 07103, USA
    Invest Ophthalmol Vis Sci 46:967-73. 2005
    ..In this study, prevention of retraction of photoreceptor axon terminals was possible by pharmacological intervention...
  10. pmc Cell-deposited matrix improves retinal pigment epithelium survival on aged submacular human Bruch's membrane
    Ilene K Sugino
    The Institute of Ophthalmology and Visual Science, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey 07101 1709, USA
    Invest Ophthalmol Vis Sci 52:1345-58. 2011
    ..To determine whether resurfacing submacular human Bruch's membrane with a cell-deposited extracellular matrix (ECM) improves retinal pigment epithelial (RPE) survival...
  11. doi request reprint Twelve-year review of pediatric traumatic open globe injuries in an urban U.S. population
    Sebastian P Lesniak
    Institute of Ophthalmology and Visual Science, New Jersey Medical School, 90 Bergen Street, Suite 6100, Newark, NJ 07101, USA
    J Pediatr Ophthalmol Strabismus 49:73-9. 2012
    ....
  12. ncbi request reprint Impaired RPE survival on aged submacular human Bruch's membrane
    Vamsi K Gullapalli
    Institute of Ophthalmology and Visual Science, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, NJ, USA
    Exp Eye Res 80:235-48. 2005
    ....
  13. doi request reprint 23-Gauge pars plana vitrectomy with pars plana Baerveldt tube placement for refractory glaucoma
    Anton M Kolomeyer
    The Institute of Ophthalmology and Visual Science, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey 07013, USA
    Eur J Ophthalmol 22:90-4. 2012
    ....
  14. doi request reprint 360° retinectomy for the treatment of complex retinal detachment
    Anton M Kolomeyer
    Institute of Ophthalmology and Visual Science New Jersey Medical School, Newark, New Jersey, USA
    Retina 31:266-74. 2011
    ..To review the anatomical and functional outcomes of eyes that underwent 360° retinectomy for a variety of indications and compare them with previously published results...
  15. ncbi request reprint Age-related macular degeneration and retinal pigment epithelium wound healing
    Ilene K Sugino
    Institute of Ophthalmology and Visual Science, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, 90 Bergen Street, Box 1709, Newark, NJ 07101 1709, USA
    Mol Neurobiol 28:177-94. 2003
    ..An understanding of the factors that influence RPE wound healing might lead to treatments that stimulate RPE resurfacing and improve visual outcome after CNV excision...
  16. ncbi request reprint Short-term study of retinal pigment epithelium sheet transplants onto Bruch's membrane
    Hao Wang
    Department of Ophthalmology, Institute of Ophthalmology and Visual Science, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, 90 Bergen Street, 6th Floor, Newark, NJ 07101 1709, USA
    Exp Eye Res 78:53-65. 2004
    ..The survival and effectiveness of retinal pigment epithelium sheet transplants appeared similar to the retinal pigment epithelium microaggregates transplants conducted previously in this model...
  17. doi request reprint Open globe ocular trauma: functional outcome of eyes with no light perception at initial presentation
    Nishant G Soni
    Institute of Ophthalmology and Visual Sciences, New Jersey Medical School, Newark, New Jersey, USA
    Retina 33:380-6. 2013
    ..To evaluate characteristics and prognostic factors for functional success in eyes that present with no light perception (NLP) after open globe trauma...
  18. ncbi request reprint Migration and proliferation of retinal pigment epithelium on extracellular matrix ligands
    Hao Wang
    Institute of Opthalmology and Visual Science, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, NJ 07103, USA
    J Rehabil Res Dev 43:713-22. 2006
    ..In general, fetal RPE resurfacing was much greater than that seen with aged RPE on comparable surfaces. The degree of cell proliferation (labeled by Ki-67) was much greater in fetal than adult RPE cells...
  19. ncbi request reprint Iris pigment epithelium attachment to aged submacular human Bruch's membrane
    Hiroshi Itaya
    Institute of Ophthalmology and Visual Science, University of Medicine and Dentistry of New Jersey New Jersey Medical School, 90 Bergen Street, Newark, NJ 07101 1709, USA
    Invest Ophthalmol Vis Sci 45:4520-8. 2004
    ....
  20. ncbi request reprint Retinal pigment epithelium wound healing in human Bruch's membrane explants
    Hao Wang
    University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, New Jersey 07103 2499, USA
    Invest Ophthalmol Vis Sci 44:2199-210. 2003
    ..To compare retinal pigment epithelium (RPE) resurfacing on the RPE basement membrane and inner collagenous layer (ICL) in human submacular Bruch's membrane explants...
  21. ncbi request reprint Biochemical Restoration of Aged Human Bruch's Membrane: Experimental Studies to Improve Retinal Pigment Epithelium Transplant Survival and Differentiation
    Ilene K Sugino
    Institute of Ophthalmology and Visual Science, Rutgers New Jersey Medical School, Rutgers University, Newark, N J, USA
    Dev Ophthalmol 53:133-42. 2014
    ..2014 S. Karger AG, Basel. ..
  22. doi request reprint Diagnostic value of clinical examination and radiographic imaging in identification of intraocular foreign bodies in open globe injury
    Shriji N Patel
    The Institute of Ophthalmology and Visual Science, New Jersey Medical School, Newark, New Jersey 07103, USA
    Eur J Ophthalmol 22:259-68. 2012
    ..To evaluate the diagnostic accuracy of clinical eye examination and radiographic imaging in the identification of intraocular foreign bodies (IOFBs) in open-globe traumatic injuries...
  23. pmc Pars plana Baerveldt tube insertion with pars plana vitrectomy for refractory glaucoma
    Anton M Kolomeyer
    The Institute of Ophthalmology and Visual Science, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, USA
    Oman J Ophthalmol 5:19-27. 2012
    ..This approach may lead to complications such as corneal decompensation, and so a pars plana approach is used in at risk eyes...
  24. ncbi request reprint Nanomedicine in ophthalmology: the new frontier
    Marco A Zarbin
    Institute of Ophthalmology and Visual Science, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, 90 Bergen Street, Newark, NJ, USA
    Am J Ophthalmol 150:144-162.e2. 2010
    ..To review the fields of nanotechnology and nanomedicine as they relate to the development of treatments for vision-threatening disorders...
  25. doi request reprint Nanotechnology in ophthalmology
    Marco A Zarbin
    Institute of Ophthalmology and Visual Science, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, NJ 07103, USA
    Can J Ophthalmol 45:457-76. 2010
    ..These obstacles are not insurmountable, and revolutionary treatments for ophthalmic diseases are expected to result from this burgeoning field...
  26. doi request reprint Ophthalmic evaluations in clinical studies of fingolimod (FTY720) in multiple sclerosis
    Marco A Zarbin
    Institute of Ophthalmology and Visual Science, New Jersey Medical School, Newark, New Jersey 07103, USA
    Ophthalmology 120:1432-9. 2013
    ..To report outcomes of ophthalmic evaluations in clinical studies of patients receiving fingolimod (Gilenya; Novartis Pharma AG, Basel, Switzerland) for multiple sclerosis (MS)...
  27. doi request reprint Regenerative nanomedicine and the treatment of degenerative retinal diseases
    Marco A Zarbin
    Institute of Ophthalmology and Visual Science, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ, USA
    Wiley Interdiscip Rev Nanomed Nanobiotechnol 4:113-37. 2012
    ....
  28. ncbi request reprint Penetrating trauma associated with findings of multiple evanescent white dot syndrome in the second eye: coincidence or an atypical case of sympathetic ophthalmia?
    Michael Landolfi
    Institute of Ophthalmology and Visual Science, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ 07101, USA
    Retina 24:637-45. 2004
    ..To report a case of sympathetic ophthalmia (SO) resembling multiple evanescent white dot syndrome (MEWDS)...
  29. ncbi request reprint 23-Gauge pars plana vitrectomy with pars plana Baerveldt tube placement for refractory glaucoma
    Anton M Kolomeyer
    The Institute of Ophthalmology and Visual Science, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey USA
    Eur J Ophthalmol 22:87-91. 2012
    ..Conclusions. A combined 23-gauge vitrectomy and pars plana Baerveldt tube insertion could be considered a useful procedure in reducing IOP and the number of glaucoma medications in eyes with refractory glaucoma...
  30. ncbi request reprint Clinical results with the use of a temporary keratoprosthesis in combined penetrating keratoplasty and vitreoretinal surgery
    Albert S Khouri
    Institute of Ophthalmology and Visual Science, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, NJ 07103, USA
    Eur J Ophthalmol 20:885-91. 2010
    ..To evaluate surgical outcomes using a temporary intraoperative keratoprosthesis (KP) in patients undergoing combined pars plana vitrectomy (PPV) and penetrating keratoplasty (PKP)...
  31. doi request reprint Diabetic macular edema: pathogenesis and treatment
    Neelakshi Bhagat
    The Institute of Ophthalmology and Visual Science, New Jersey Medical School, Newark, New Jersey, USA
    Surv Ophthalmol 54:1-32. 2009
    ..It seems that combined pharmacologic and surgical therapy may be the best approach for the management of macular edema in diabetic patients...
  32. ncbi request reprint Adeno-associated virus encoding green fluorescent protein as a label for retinal pigment epithelium
    Kathleen A Hansen
    Institute of Ophthalmology and Visual Science, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey 01701, USA
    Invest Ophthalmol Vis Sci 44:772-80. 2003
    ..To determine whether transduction with adeno-associated virus encoding green fluorescent protein (AAV-GFP) is useful for labeling transplanted retinal pigment epithelial cells (RPE)...
  33. ncbi request reprint Age-related macular degeneration: clinical findings, histopathology and imaging techniques
    Marco A Zarbin
    Rutgers New Jersey Medical School, Newark, N J, USA
    Dev Ophthalmol 53:1-32. 2014
    ..As a result, these imaging technologies may be valuable in assessing the effects of cell-based therapy for patients with AMD. © 2014 S. Karger AG, Basel. ..
  34. pmc Ranibizumab in patients with dense cataract and proliferative diabetic retinopathy with rubeosis
    Yufei Tu
    The Institute of Ophthalmology and Visual Science, New Jersey Medical School, 90 Bergen Street Suite 6100, Newark, New Jersey, USA
    Oman J Ophthalmol 5:161-5. 2012
    ....
  35. pmc Complications in resident-performed phacoemulsification cataract surgery at New Jersey Medical School
    Neelakshi Bhagat
    The Institute of Ophthalmology and Visual Science, New Jersey Medical School, Doctors Office Center, Suite 6168, 90 Bergen Street, Newark, NJ 07103, USA
    Br J Ophthalmol 91:1315-7. 2007
    ....
  36. ncbi request reprint Ultrastructural analysis of hydraulic and abrasive retinal pigment epithelial cell debridements
    Debra S Leonard
    Department of Ophthalmology, Institute of Ophthalmology and Visual Science, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, 90 Bergen Street, DOC 6th floor, P O Box 1709, Newark, NJ 07101 1709, USA
    Exp Eye Res 76:473-91. 2003
    ..This finding may mean that retinal pigment epithelial cells are not able to resurface completely and permanently areas showing geographic atrophy of the choriocapillaris...
  37. ncbi request reprint Synaptic plasticity in mammalian photoreceptors prepared as sheets for retinal transplantation
    Mohamad A Khodair
    Department of Neurosciences, Graduate School of Biomedical Sciences, University of Medicine and Dentistry of New Jersey, Newark, New Jersey 07103, USA
    Invest Ophthalmol Vis Sci 44:4976-88. 2003
    ..To investigate systematically the early morphologic changes in axon terminals of adult mammalian rod and cone photoreceptors prepared as a sheet for subretinal transplantation...
  38. ncbi request reprint BDNF reduces the retinal toxicity of verteporfin photodynamic therapy
    Daniel M Paskowitz
    Department of Ophthalmology, University of California, San Francisco, 94143 0730, USA
    Invest Ophthalmol Vis Sci 45:4190-6. 2004
    ..In the current study, it was found that the neuroprotective agent brain-derived neurotrophic factor (BDNF) reduces this retinal damage...
  39. ncbi request reprint Neurotrophic factors minimize the retinal toxicity of verteporfin photodynamic therapy
    Daniel M Paskowitz
    Department of Ophthalmology, University of California, San Francisco, California 94143, USA
    Invest Ophthalmol Vis Sci 48:430-7. 2007
    ..Also investigated was whether protection would be observed after a second round of PDT with adjunctive BDNF treatment...
  40. ncbi request reprint Functionalizing cell-based therapy for age-related macular degeneration
    Marco A Zarbin
    Am J Ophthalmol 143:681-2. 2007
  41. ncbi request reprint Perimetric sensitivity and retinal thickness in eyes with macular edema resulting from branch retinal vein occlusion
    Neelakshi Bhagat
    Am J Ophthalmol 133:428-9. 2002
  42. pmc Analysis of retinal pigment epithelium integrin expression and adhesion to aged submacular human Bruch's membrane
    Marco A Zarbin
    Trans Am Ophthalmol Soc 101:499-520. 2003
    ..Uncultured aged retinal pigment epithelium (RPE) does not resurface aged Bruch's membrane after 24 hours in organ culture. These experiments assess whether culturing alters RPE integrin expression and resurfacing of Bruch's membrane...
  43. ncbi request reprint Photodynamic therapy and high-dose intravitreal triamcinolone to treat exudative age-related macular degeneration: 1-year outcome
    José María Ruiz-Moreno
    Department of Ophthalmology, Miguel Hernandez University School of Medicine, Alicante, Spain
    Retina 26:602-12. 2006
    ..To evaluate the efficacy of photodynamic therapy with verteporfin (PDT) and high-dose intravitreous triamcinolone acetonide to treat choroidal new vessels (CNVs) associated with age-related macular degeneration (AMD)...
  44. ncbi request reprint Macular atrophy after photocoagulation of soft drusen
    José Ruiz-Moreno
    Department of Ophthalmology, Miguel Hernandez University School of Medicine, and Instituto Oftalmológico de Alicante, Spain
    Retina 23:315-21. 2003
    ..To analyze the appearance and characteristics of macular atrophy after photocoagulation of soft drusen...
  45. ncbi request reprint Photodynamic therapy and high-dose intravitreal triamcinolone to treat exudative age-related macular degeneration: 2-year outcome
    Jose M Ruiz-Moreno
    Department of Ophthalmology, Miguel Hernandez University School of Medicine, Alicante, Spain
    Retina 27:458-61. 2007
    ....
  46. ncbi request reprint Retinal damage caused by photodynamic therapy can be reduced using BDNF
    Jacque L Duncan
    University of California, San Francisco, California 94143, USA
    Adv Exp Med Biol 572:297-302. 2006