STEVE S ZALCMAN

Summary

Affiliation: New Jersey
Country: USA

Publications

  1. pmc Pharmacokinetics and modeling of immune cell trafficking: quantifying differential influences of target tissues versus lymphocytes in SJL and lipopolysaccharide-treated mice
    William A Banks
    GRECC, Veterans Affairs Puget Sound Health Care System, Seattle, WA, USA
    J Neuroinflammation 9:231. 2012
  2. ncbi request reprint Interleukin-6 increases sensitivity to the locomotor-stimulating effects of amphetamine in rats
    S Zalcman
    Center for Studies in Behavioral Neurobiology, Concordia University, Montreal, Quebec, Canada
    Brain Res 847:276-83. 1999
  3. ncbi request reprint Interleukin-2 potentiates novelty- and GBR 12909-induced exploratory activity
    S S Zalcman
    Department of Psychiatry and Rutgers UMDNJ Integrative Neuroscience Program, UMD New Jersey Medical School, Medical Science Building, E 503, 185 S Orange Ave, Newark, NJ 07103 2714, USA
    Brain Res 899:1-9. 2001
  4. ncbi request reprint Interleukin-2-induced increases in climbing behavior: inhibition by dopamine D-1 and D-2 receptor antagonists
    Steven S Zalcman
    UMD New Jersey Medical School, Department of Psychiatry and Rutgers UMDNJ Integrative Neuroscience Program, Newark, NJ 07103, USA
    Brain Res 944:157-64. 2002
  5. ncbi request reprint The neurobiology of aggression and rage: role of cytokines
    Steven S Zalcman
    Department of Psychiatry, UMDNJ New Jersey Medical School, Newark, NJ 07103, USA
    Brain Behav Immun 20:507-14. 2006
  6. ncbi request reprint Kainate-activated currents in the ventral tegmental area of neonatal rats are modulated by interleukin-2
    Jiang Hong Ye
    Department of Anesthesiology, New Jersey Medical School UMDNJ, Newark, NJ 07103 2714, USA
    Brain Res 1049:227-33. 2005
  7. pmc Role of IL-1 beta and 5-HT2 receptors in midbrain periaqueductal gray (PAG) in potentiating defensive rage behavior in cat
    Suresh Bhatt
    Department of Neurology and Neurosciences, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, 185 South Orange Avenue, Newark, NJ 07103, USA
    Brain Behav Immun 22:224-33. 2008
  8. ncbi request reprint Permeability of the mouse blood-brain barrier to murine interleukin-2: predominance of a saturable efflux system
    William A Banks
    Division of Geriatrics, Department of Internal Medicine, GRECC, Veterans Affairs Medical Center St Louis and Saint Louis University School of Medicine, 915 N Grand Blvd, St Louis, MO 63106, USA
    Brain Behav Immun 18:434-42. 2004

Research Grants

  1. IL2 Neuroimmunology and Behavior
    Steve Zalcman; Fiscal Year: 2009
  2. Psychoneuroimmunology of T Cell Activation
    Steve Zalcman; Fiscal Year: 2004
  3. IL2 Neuroimmunology and Behavior
    Steve Zalcman; Fiscal Year: 2007

Collaborators

Detail Information

Publications8

  1. pmc Pharmacokinetics and modeling of immune cell trafficking: quantifying differential influences of target tissues versus lymphocytes in SJL and lipopolysaccharide-treated mice
    William A Banks
    GRECC, Veterans Affairs Puget Sound Health Care System, Seattle, WA, USA
    J Neuroinflammation 9:231. 2012
    ..Immune cell trafficking into the CNS and other tissues plays important roles in health and disease. Rapid quantitative methods are not available that could be used to study many of the dynamic aspects of immune cell-tissue interactions...
  2. ncbi request reprint Interleukin-6 increases sensitivity to the locomotor-stimulating effects of amphetamine in rats
    S Zalcman
    Center for Studies in Behavioral Neurobiology, Concordia University, Montreal, Quebec, Canada
    Brain Res 847:276-83. 1999
    ..The fact that IL-6 caused a lasting change in responsiveness to amphetamine implies a mechanism by which immunogenic stimuli can alter brain circuitry, changing its sensitivity to seemingly unrelated subsequent stimuli or events...
  3. ncbi request reprint Interleukin-2 potentiates novelty- and GBR 12909-induced exploratory activity
    S S Zalcman
    Department of Psychiatry and Rutgers UMDNJ Integrative Neuroscience Program, UMD New Jersey Medical School, Medical Science Building, E 503, 185 S Orange Ave, Newark, NJ 07103 2714, USA
    Brain Res 899:1-9. 2001
    ..847 (1999) 276-283), it is suggested that cytokines can influence the development of behavioral abnormalities that are characteristic of aberrant mesolimbic dopamine activity via sensitization-like processes...
  4. ncbi request reprint Interleukin-2-induced increases in climbing behavior: inhibition by dopamine D-1 and D-2 receptor antagonists
    Steven S Zalcman
    UMD New Jersey Medical School, Department of Psychiatry and Rutgers UMDNJ Integrative Neuroscience Program, Newark, NJ 07103, USA
    Brain Res 944:157-64. 2002
    ..These findings could shed light on the mechanisms by which IL-2 increases vulnerability to psychiatric abnormalities associated with aberrations in central dopaminergic processes...
  5. ncbi request reprint The neurobiology of aggression and rage: role of cytokines
    Steven S Zalcman
    Department of Psychiatry, UMDNJ New Jersey Medical School, Newark, NJ 07103, USA
    Brain Behav Immun 20:507-14. 2006
    ..Present research is designed to further delineate the roles of cytokines in aggressive behavior and to begin to unravel the possible signaling pathways involved this process...
  6. ncbi request reprint Kainate-activated currents in the ventral tegmental area of neonatal rats are modulated by interleukin-2
    Jiang Hong Ye
    Department of Anesthesiology, New Jersey Medical School UMDNJ, Newark, NJ 07103 2714, USA
    Brain Res 1049:227-33. 2005
    ..IL-2 might thus be required for normal cell development in the mesolimbic and mesostriatal systems...
  7. pmc Role of IL-1 beta and 5-HT2 receptors in midbrain periaqueductal gray (PAG) in potentiating defensive rage behavior in cat
    Suresh Bhatt
    Department of Neurology and Neurosciences, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, 185 South Orange Avenue, Newark, NJ 07103, USA
    Brain Behav Immun 22:224-33. 2008
    ..The present study demonstrates that IL-beta in the dorsal PAG, similar to the medial hypothalamus, potentiates defensive rage behavior and is mediated through a 5-HT(2C) receptor mechanism...
  8. ncbi request reprint Permeability of the mouse blood-brain barrier to murine interleukin-2: predominance of a saturable efflux system
    William A Banks
    Division of Geriatrics, Department of Internal Medicine, GRECC, Veterans Affairs Medical Center St Louis and Saint Louis University School of Medicine, 915 N Grand Blvd, St Louis, MO 63106, USA
    Brain Behav Immun 18:434-42. 2004
    ..This is the first description of a saturable CNS-to-blood efflux system for a cytokine. We postulate that this efflux system may protect the brain from circulating IL-2...

Research Grants5

  1. IL2 Neuroimmunology and Behavior
    Steve Zalcman; Fiscal Year: 2009
    ....
  2. Psychoneuroimmunology of T Cell Activation
    Steve Zalcman; Fiscal Year: 2004
    ..abstract_text> ..
  3. IL2 Neuroimmunology and Behavior
    Steve Zalcman; Fiscal Year: 2007
    ....