Genomes and Genes
Jeffrey Zheng Sheng Ye
Affiliation: New York University
- POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complexJeffrey Zheng Sheng Ye
Laboratory for Cell Biology and Genetics and Laboratory for Mass Spectrometry and Gaseous Ion Chemistry, The Rockefeller University, New York, New York 10021, USA
Genes Dev 18:1649-54. 2004..Reduction of PIP1 or POT1 levels with shRNAs led to telomere elongation, indicating that PIP1 contributes to telomere length control through recruitment of POT1...
- TIN2 binds TRF1 and TRF2 simultaneously and stabilizes the TRF2 complex on telomeresJeffrey Zheng Sheng Ye
Laboratory for Cell Biology and Genetics, The Rockefeller University, New York, New York 10021, USA
J Biol Chem 279:47264-71. 2004..The TIN2-mediated cooperative binding of TRF1 and TRF2 to telomeres has important implications for the mechanism of telomere length regulation and protection...
- TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complexJeffrey Zheng Sheng Ye
The Rockefeller University, 1230 York Avenue, New York, New York 10021, USA
Nat Genet 36:618-23. 2004..These data identify TIN2 as a PARP modulator in the TRF1 complex and can explain how TIN2 contributes to the regulation of telomere length...