Sunil Wimalawansa

Summary

Affiliation: New Jersey
Country: USA

Publications

  1. doi request reprint Vitamin D: an essential component for skeletal health
    Sunil J Wimalawansa
    Division of Endocrinology, Metabolism and Nutrition, Department of Medicine, and UMDNJ, Robert Wood Johnson Medical School, Physiology and Integrative Biology, Graduate School of Biomedical Sciences, New Brunswick, New Jersey 08903 0019, USA
    Ann N Y Acad Sci 1240:E1-12. 2011
  2. doi request reprint Vitamin D in the new millennium
    Sunil J Wimalawansa
    Physiology and Integrative Biology, Endocrinology, Metabolism and Nutrition, UMDNJ Robert Wood Johnson Medical School, New Brunswick, NJ, USA
    Curr Osteoporos Rep 10:4-15. 2012
  3. doi request reprint Nitric oxide and bone
    Sunil J Wimalawansa
    Department of Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, NJ, USA
    Ann N Y Acad Sci 1192:391-403. 2010
  4. pmc Transdermal nitroglycerin therapy may not prevent early postmenopausal bone loss
    Sunil J Wimalawansa
    Division of Endocrinology, Department of Medicine, Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903 0019, USA
    J Clin Endocrinol Metab 94:3356-64. 2009
  5. ncbi request reprint Bisphosphonate-associated osteomyelitis of the jaw: guidelines for practicing clinicians
    Sunil J Wimalawansa
    Division of Endocrinology, Metabolism and Nutrition, Department of Medicine, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, New Brunswick, New Jersey 08903 0019, USA
    Endocr Pract 14:1150-68. 2008
  6. ncbi request reprint Nitric oxide: novel therapy for osteoporosis
    Sunil J Wimalawansa
    Regional Osteoporosis Center, Division of Endocrinology, Metabolism and Nutrition, Department of Medicine, Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA
    Expert Opin Pharmacother 9:3025-44. 2008
  7. ncbi request reprint Nitric oxide: new evidence for novel therapeutic indications
    Sunil J Wimalawansa
    Robert Wood Johnson Medical School, Department of Medicine, New Brunswick, NJ 08903, USA
    Expert Opin Pharmacother 9:1935-54. 2008
  8. ncbi request reprint Insight into bisphosphonate-associated osteomyelitis of the jaw: pathophysiology, mechanisms and clinical management
    Sunil J Wimalawansa
    Department of Medicine, Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA
    Expert Opin Drug Saf 7:491-512. 2008
  9. ncbi request reprint Rationale for using nitric oxide donor therapy for prevention of bone loss and treatment of osteoporosis in humans
    Sunil J Wimalawansa
    Division of Endocrinology and Metabolism, Robert Wood Johnson Medical School, 372 MEB, New Brunswick, NJ 08903 0019, USA
    Ann N Y Acad Sci 1117:283-97. 2007
  10. ncbi request reprint Breastfeeding and postmenopausal osteoporosis
    Julia P Grimes
    Division of Endocrinology, Department of Medicine, UMDNJ Robert Wood Johnson Medical School, One Robert Wood Johnson Place 372 MEB, PO Box 19, New Brunswick, NJ 08903 0019, USA
    Curr Womens Health Rep 3:193-8. 2003

Research Grants

Collaborators

Detail Information

Publications17

  1. doi request reprint Vitamin D: an essential component for skeletal health
    Sunil J Wimalawansa
    Division of Endocrinology, Metabolism and Nutrition, Department of Medicine, and UMDNJ, Robert Wood Johnson Medical School, Physiology and Integrative Biology, Graduate School of Biomedical Sciences, New Brunswick, New Jersey 08903 0019, USA
    Ann N Y Acad Sci 1240:E1-12. 2011
    ..Additional research is needed to clarify the relationship between vitamin D and the nonskeletal systems, nonclassic functions, and targets of vitamin D...
  2. doi request reprint Vitamin D in the new millennium
    Sunil J Wimalawansa
    Physiology and Integrative Biology, Endocrinology, Metabolism and Nutrition, UMDNJ Robert Wood Johnson Medical School, New Brunswick, NJ, USA
    Curr Osteoporos Rep 10:4-15. 2012
    ..Other vulnerable patients, such as the obese, those who have undergone bariatric surgery, and those with gastrointestinal malabsorption syndromes, may require higher doses of vitamin D to maintain normal serum levels and be healthy...
  3. doi request reprint Nitric oxide and bone
    Sunil J Wimalawansa
    Department of Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, NJ, USA
    Ann N Y Acad Sci 1192:391-403. 2010
    ..Large numbers of animal studies and human pilot studies support the concept of using NO donors for preventing bone loss. Administration of exogenous NO or prolonging endogenous NO activity are practical ways to supplement NO...
  4. pmc Transdermal nitroglycerin therapy may not prevent early postmenopausal bone loss
    Sunil J Wimalawansa
    Division of Endocrinology, Department of Medicine, Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903 0019, USA
    J Clin Endocrinol Metab 94:3356-64. 2009
    ..Osteoporosis is common among postmenopausal women; animal studies and human pilot studies support the concept of nitric oxide (NO) donors reducing bone mineral density loss...
  5. ncbi request reprint Bisphosphonate-associated osteomyelitis of the jaw: guidelines for practicing clinicians
    Sunil J Wimalawansa
    Division of Endocrinology, Metabolism and Nutrition, Department of Medicine, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, New Brunswick, New Jersey 08903 0019, USA
    Endocr Pract 14:1150-68. 2008
    ..To evaluate the literature and discuss the risk factors, mechanisms, pathophysiologic aspects, and recommended management of bisphosphonate-associated osteomyelitis of the jaw (BAOMJ)...
  6. ncbi request reprint Nitric oxide: novel therapy for osteoporosis
    Sunil J Wimalawansa
    Regional Osteoporosis Center, Division of Endocrinology, Metabolism and Nutrition, Department of Medicine, Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA
    Expert Opin Pharmacother 9:3025-44. 2008
    ..Excess or inappropriate local production of NO aggravates bone destruction in some diseases such as septic shock, rheumatoid and other inflammatory arthropathies...
  7. ncbi request reprint Nitric oxide: new evidence for novel therapeutic indications
    Sunil J Wimalawansa
    Robert Wood Johnson Medical School, Department of Medicine, New Brunswick, NJ 08903, USA
    Expert Opin Pharmacother 9:1935-54. 2008
    ..NO donor therapies are indicated in these conditions...
  8. ncbi request reprint Insight into bisphosphonate-associated osteomyelitis of the jaw: pathophysiology, mechanisms and clinical management
    Sunil J Wimalawansa
    Department of Medicine, Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA
    Expert Opin Drug Saf 7:491-512. 2008
    ..Bisphosphonate-associated osteomyelitis of the jaw (BAOMJ) affects 1 per 100,000 patients-treated years for non-cancer bone diseases and approximately 1 - 2% of cancer patients treated with bisphosphonates...
  9. ncbi request reprint Rationale for using nitric oxide donor therapy for prevention of bone loss and treatment of osteoporosis in humans
    Sunil J Wimalawansa
    Division of Endocrinology and Metabolism, Robert Wood Johnson Medical School, 372 MEB, New Brunswick, NJ 08903 0019, USA
    Ann N Y Acad Sci 1117:283-97. 2007
    ..If results of this study confirm our hypothesis, it is plausible that nitroglycerine therapy may supplant estrogen replacement and SERMs in preventing and treating postmenopausal osteoporosis...
  10. ncbi request reprint Breastfeeding and postmenopausal osteoporosis
    Julia P Grimes
    Division of Endocrinology, Department of Medicine, UMDNJ Robert Wood Johnson Medical School, One Robert Wood Johnson Place 372 MEB, PO Box 19, New Brunswick, NJ 08903 0019, USA
    Curr Womens Health Rep 3:193-8. 2003
    ..Better understanding of this relationship will provide new opportunities for early intervention and ultimately help in the prevention of bone loss in postmenopausal women...
  11. ncbi request reprint Bones and nutrition: common sense supplementation for osteoporosis
    Sonoo Advani
    Division of Endocrinology, Department of Medicine, UMDNJ Robert Wood Johnson Medical School, One Robert Wood Johnson Place 372 MEB, PO Box 19, New Brunswick, NJ 08903 0019, USA
    Curr Womens Health Rep 3:187-92. 2003
    ..In this article, the roles of diet and nutritional supplementation in preventing and treating osteoporosis are reviewed...
  12. ncbi request reprint The efficacy of acute administration of pamidronate on the conservation of bone mass following severe burn injury in children: a double-blind, randomized, controlled study
    Gordon L Klein
    Children s Hospital, University of Texas Medical Branch, 301 University Boulevard, Galveston, Texas, TX 77555 0352, USA
    Osteoporos Int 16:631-5. 2005
    ..In summary, acute intravenous pamidronate administration following burns may help to preserve bone mass, perhaps by inhibiting the glucocorticoid-induced apoptosis of osteoblasts and osteocytes...
  13. ncbi request reprint Model for bone strength and osteoporotic fractures
    Gemunu H Gunaratne
    Department of Physics, University of Houston, Houston, Texas 77204, USA
    Phys Rev Lett 88:068101. 2002
    ..The "stress backbones" and histograms of stress distributions for healthy and weak networks are shown to be qualitatively different. A hereto untested relationship between bone density and bone strength is presented...
  14. pmc Testing two predictions for fracture load using computer models of trabecular bone
    Michael A K Liebschner
    Department of Bioengineering, Rice University, Houston, Texas, USA
    Biophys J 89:759-67. 2005
    ..Since Gamma can be computed from a vibrational assessment of bone, we argue that the latter can be used to introduce new surrogates for bone strength and hence diagnostic tools for osteoporosis...
  15. ncbi request reprint Adrenomedullin antagonist treatment during early gestation in rats causes fetoplacental growth restriction through apoptosis
    Josthna Penchalaneni
    Department of Obstetrics and Gynecology, University of Texas Medical Branch, 301 University Blvd, Galveston, Texas 77555, USA
    Biol Reprod 71:1475-83. 2004
    ..In conclusion, these findings show that antagonism of AM in rats during early pregnancy caused fetoplacental growth restriction through the activation of mitochondrial apoptotic pathways...
  16. ncbi request reprint An expression relating breaking stress and density of trabecular bone
    Chamith S Rajapakse
    Department of Physics, University of Houston, Houston, TX 77204, USA
    J Biomech 37:1241-9. 2004
    ..In addition, changes caused by trabecular thinning and anisotropy can be modeled by the expression...
  17. ncbi request reprint Adrenomedullin requires an intact nitric oxide system to function as an endogenous vasodilator in rat gestation
    Andrea G Witlin
    Obstetrics and Gynecology Department, The University of Texas Medical Branch at Galveston, Galveston, TX 77555 1066, USA
    Hypertens Pregnancy 22:9-24. 2003
    ....

Research Grants9

  1. Prevention of Postmenopausal Bone Loss with Nitric Oxide
    Sunil Wimalawansa; Fiscal Year: 2006
    ..The study will also pave the way for the future for providing more acceptable affordable and cost-effective therapies for the prevention of postmenopausal osteoporosis. ..
  2. Prevention of Postmenopausal Bone Loss with Nitric Oxide
    Sunil Wimalawansa; Fiscal Year: 2007
    ..The study will also pave the way for the future, for providing more acceptable, affordable and cost- effective therapies for the prevention of postmenopausalosteoporosis. ..