Connie M Westhoff

Summary

Affiliation: New York Blood Center
Country: USA

Publications

  1. doi request reprint Nucleotide deletion in RHCE*cE (907delC) is responsible for a D- - haplotype in Hispanics
    Connie M Westhoff
    National Molecular Blood Group and Platelet Testing Laboratory and NRLBGS, National Reference Laboratory for Blood Group Serology, American Red Cross, Philadelphia, Pennsylvania, USA
    Transfusion 51:2142-7. 2011
  2. pmc RHCE*ceMO is frequently in cis to RHD*DAU0 and encodes a hr(S) -, hr(B) -, RH:-61 phenotype in black persons: clinical significance
    Connie M Westhoff
    Laboratory of Immunohematology and Genomics, New York Blood Center Laboratory of Immunochemistry, New York Blood Center, New York, New York National Molecular Testing Laboratory, American Red Cross, Philadelphia, Pennsylvania
    Transfusion 53:2983-9. 2013
  3. pmc RHCE*ceTI encodes partial c and partial e and is often in cis to RHD*DIVa
    Connie M Westhoff
    Laboratory of Immunohematology and Genomics, New York Blood Center, Long Island City, New York 10065, USA
    Transfusion 53:741-6. 2013
  4. pmc The JAL antigen (RH48) is the result of a change in RHCE that encodes Arg114Trp
    Connie M Westhoff
    Molecular Blood Group and Platelet Testing Laboratory, American Red Cross, Penn Jersey Region, Philadelphia, PA 19130, USA
    Transfusion 49:725-32. 2009
  5. doi request reprint High prevalence of red blood cell alloimmunization in sickle cell disease despite transfusion from Rh-matched minority donors
    Stella T Chou
    Division of Hematology, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Blood 122:1062-71. 2013
  6. pmc DIIIa and DIII Type 5 are encoded by the same allele and are associated with altered RHCE*ce alleles: clinical implications
    Connie M Westhoff
    National Molecular Blood Group and Platelet Testing Laboratory, American Red Cross, Philadelphia, Pennsylvania, USA
    Transfusion 50:1303-11. 2010
  7. ncbi request reprint Characterization of ammonia transport by the kidney Rh glycoproteins RhBG and RhCG
    Don On Daniel Mak
    American Red Cross, 700 Spring Garden St, Philadelphia, PA 19123, USA
    Am J Physiol Renal Physiol 290:F297-305. 2006
  8. ncbi request reprint Molecular testing for transfusion medicine
    Connie M Westhoff
    American Red Cross, Philadelphia, Pennsylvania 19130, USA
    Curr Opin Hematol 13:471-5. 2006
  9. ncbi request reprint Rh complexities: serology and DNA genotyping
    Connie M Westhoff
    American Red Cross, and Division of Transfusion Medicine, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19123, USA
    Transfusion 47:17S-22S. 2007
  10. doi request reprint A novel JKA allele, nt561C>A, associated with silencing of Kidd expression
    Trina Horn
    National Molecular Blood Group and Platelet Antigen Testing Laboratory, American Red Cross, Philadelphia, PA, USA
    Transfusion 52:1092-6. 2012

Collaborators

Detail Information

Publications14

  1. doi request reprint Nucleotide deletion in RHCE*cE (907delC) is responsible for a D- - haplotype in Hispanics
    Connie M Westhoff
    National Molecular Blood Group and Platelet Testing Laboratory and NRLBGS, National Reference Laboratory for Blood Group Serology, American Red Cross, Philadelphia, Pennsylvania, USA
    Transfusion 51:2142-7. 2011
    ..We investigated RH in eight samples, three presenting as D- -, whose c-E- red blood cell (RBC) typing was discordant with the RHCE genotype that predicted c+E+...
  2. pmc RHCE*ceMO is frequently in cis to RHD*DAU0 and encodes a hr(S) -, hr(B) -, RH:-61 phenotype in black persons: clinical significance
    Connie M Westhoff
    Laboratory of Immunohematology and Genomics, New York Blood Center Laboratory of Immunochemistry, New York Blood Center, New York, New York National Molecular Testing Laboratory, American Red Cross, Philadelphia, Pennsylvania
    Transfusion 53:2983-9. 2013
    ..We compiled serologic and DNA testing data on samples with RHCE*ceMO to determine the red blood cell (RBC) antigen expression, antibody specificity, RHD association, and the prevalence in African-American persons...
  3. pmc RHCE*ceTI encodes partial c and partial e and is often in cis to RHD*DIVa
    Connie M Westhoff
    Laboratory of Immunohematology and Genomics, New York Blood Center, Long Island City, New York 10065, USA
    Transfusion 53:741-6. 2013
    ..In the Rh blood group system, variant RhD and RhCE express several partial antigens. We investigated RH in samples with partial DIVa that demonstrated weak and variable reactivity with anti-C...
  4. pmc The JAL antigen (RH48) is the result of a change in RHCE that encodes Arg114Trp
    Connie M Westhoff
    Molecular Blood Group and Platelet Testing Laboratory, American Red Cross, Penn Jersey Region, Philadelphia, PA 19130, USA
    Transfusion 49:725-32. 2009
    ..This study was undertaken to investigate the RH gene(s) responsible for expression of JAL and to determine the structural relationship between JAL and other Rh antigens...
  5. doi request reprint High prevalence of red blood cell alloimmunization in sickle cell disease despite transfusion from Rh-matched minority donors
    Stella T Chou
    Division of Hematology, The Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Blood 122:1062-71. 2013
    ..Whether RH genotyping of patients and minority donors will reduce Rh alloimmunization in SCD needs to be examined. ..
  6. pmc DIIIa and DIII Type 5 are encoded by the same allele and are associated with altered RHCE*ce alleles: clinical implications
    Connie M Westhoff
    National Molecular Blood Group and Platelet Testing Laboratory, American Red Cross, Philadelphia, Pennsylvania, USA
    Transfusion 50:1303-11. 2010
    ..We also studied additional DIIIa samples to clarify the RHD background and establish the associated RHCE...
  7. ncbi request reprint Characterization of ammonia transport by the kidney Rh glycoproteins RhBG and RhCG
    Don On Daniel Mak
    American Red Cross, 700 Spring Garden St, Philadelphia, PA 19123, USA
    Am J Physiol Renal Physiol 290:F297-305. 2006
    ....
  8. ncbi request reprint Molecular testing for transfusion medicine
    Connie M Westhoff
    American Red Cross, Philadelphia, Pennsylvania 19130, USA
    Curr Opin Hematol 13:471-5. 2006
    ..This review summarizes the progress made in the last decade in applying genotyping to prenatal practice and clinical transfusion medicine...
  9. ncbi request reprint Rh complexities: serology and DNA genotyping
    Connie M Westhoff
    American Red Cross, and Division of Transfusion Medicine, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19123, USA
    Transfusion 47:17S-22S. 2007
  10. doi request reprint A novel JKA allele, nt561C>A, associated with silencing of Kidd expression
    Trina Horn
    National Molecular Blood Group and Platelet Antigen Testing Laboratory, American Red Cross, Philadelphia, PA, USA
    Transfusion 52:1092-6. 2012
    ..We determined the molecular basis for Jk(a-b-) in an African American family. DNA testing of samples from random African American, Caucasian, and Brazilian blacks was done to estimate the allele frequency...
  11. ncbi request reprint Deciphering the function of the Rh family of proteins
    Connie M Westhoff
    American Red Cross and the Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Transfusion 45:117S-21S. 2005
  12. pmc The structure and function of the Rh antigen complex
    Connie M Westhoff
    American Red Cross and Department of Pathology and Laboratory Medicine, Division of Transfusion Medicine, University of Pennsylvania, Philadelphia, PA 19123, USA
    Semin Hematol 44:42-50. 2007
    ..The Rh family of proteins now includes non-erythroid homologs present in many other tissues, and comparative genomics reveal Rh homologs in all domains of life...
  13. ncbi request reprint The Rh blood group system in review: a new face for the next decade
    Connie M Westhoff
    American Red Cross, Philadelphia, Pennsylvania 19130, USA
    Transfusion 44:1663-73. 2004
  14. ncbi request reprint A new hybrid RHCE gene (CeNR) is responsible for expression of a novel antigen
    Connie M Westhoff
    Department of Pathology and Laboratory Medicine, University of Pennsylvania and the American Red Cross, Philadelphia, Pennsylvania, USA
    Transfusion 44:1047-51. 2004
    ..The purpose of this study was to determine the molecular basis of the Rh phenotype...