Research Topics
| BARRY I WEINBERGERSummaryAffiliation: New Jersey Country: USA Publications
Research Grants
| Collaborators
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Detail Information
Publications
Sulfur mustard-induced pulmonary injury: therapeutic approaches to mitigating toxicityBarry Weinberger
Department of Pediatrics, Division of Neonatology, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, 1 Robert Wood Johnson Place, New Brunswick, NJ 08903, USA
Pulm Pharmacol Ther 24:92-9. 2011..g., doxycycline, aprotinin, ilomastat), surfactant replacement, and bronchodilators. Effective treatments may depend on the extent of lung injury and require a multi-faceted pharmacological approach...- Mechanisms mediating reduced responsiveness of neonatal neutrophils to lipoxin A4Barry Weinberger
Department of Pediatrics, UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey 08901, USA
Pediatr Res 64:393-8. 2008..This may contribute to diseases associated with chronic inflammation in neonates... 
Influence of labor on neonatal neutrophil apoptosis, and inflammatory activityBarry Weinberger
Department of Pediatrics Neonatology, UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903, USA
Pediatr Res 61:572-7. 2007..Although increased neutrophil longevity after labor is important for host defense in the immediate newborn period, it may contribute to inflammatory or oxidative injury in susceptible infants...- Inflammatory effects of phthalates in neonatal neutrophilsAnna M Vetrano
Department of Pediatrics, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick, New Jersey 08901, USA
Pediatr Res 68:134-9. 2010..These findings suggest that neonatal neutrophils are more sensitive to phthalate-mediated inhibition of PPAR-gamma, which may be related to decreased anti-inflammatory signaling... - Theophylline alters neutrophil function in preterm infantsRajeev Mehta
Department of Pediatrics Neonatology, UMDNJ Robert Wood Johnson Medical School, New Brunswick, NJ, USA
Biol Neonate 81:176-81. 2002..Altered neutrophil activity in newborns related to theophylline treatment may affect the infants' response to infection as well as the incidence of inflammatory diseases... - IFN-gamma-mediated inhibition of COX-2 expression in the placenta from term and preterm labor pregnanciesNazeeh Hanna
Division of Neonatology, Department of Pediatrics, UMDNJ Robert Wood, Johnson Medical School, New Brunswick, NJ 08903, USA
Am J Reprod Immunol 51:311-8. 2004..The aim of this study was to evaluate the effects of interferon (IFN)-gamma on the expression of Cyclooxygenase (COX)-2 and production of prostaglandin E(2) (PGE(2)) in the human placenta from term and preterm labor deliveries... - Cerebral vascular responses to changes in carbon dioxide tension in term and preterm infants with apneaAnne Koons
Division of Neonatology, Department of Pediatrics, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, St Peter s University Hospital, 254 Easton Avenue, New Brunswick, N J 08903, USA
Biol Neonate 84:115-8. 2003..We conclude that preterm, but not term, infants with apnea exhibit impaired vascular responses to hypercarbia... - Mechanisms underlying reduced apoptosis in neonatal neutrophilsNazeeh Hanna
Department of Pediatrics, UMDNJ-Robert Wood Johnson Medical School, 1 Robert Wood Johnson Place, New Brunswick, NJ 08903, USA
Pediatr Res 57:56-62. 2005..This may be related to decreased expression of both FasR and Bcl-2-family proteins that mediate neutrophil apoptosis... - Effects of ibuprofen and hypoxia on neutrophil apoptosis in neonatesNazeeh Hanna
Division of Neonatology, Department of Pediatrics, UMDNJ-Robert Wood Johnson Medical School, Rutgers University, New Brunswick, NJ 08903, USA
Biol Neonate 86:235-9. 2004..These data suggest that treatment of infants with ibuprofen, in the presence of infection and/or tissue hypoperfusion/hypoxia, may contribute to the development of inflammatory diseases... - Lipid peroxidation in cord blood and neonatal outcomeBarry Weinberger
Division of Neonatology, Department of Pediatrics, UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA
Pediatr Int 48:479-83. 2006..The aim of the present study was to determine whether fetal oxidant stress is associated with adverse effects in preterm infants... - Mechanisms mediating the biologic activity of synthetic proline, glycine, and hydroxyproline polypeptides in human neutrophilsBarry Weinberger
Division of Neonatology, Department of Pediatrics, UMDNJ Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA
Mediators Inflamm 2005:31-8. 2005..However, distinct calcium-independent signaling pathways appear to be involved in these activities... - Association of lipid peroxidation with hepatocellular injury in preterm infantsBarry Weinberger
University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick, NJ, USA
Crit Care 6:521-5. 2002.... - Oxygen toxicity in premature infantsBarry Weinberger
Department of Pediatrics/Neonatology, UMDNJ-Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903, USA
Toxicol Appl Pharmacol 181:60-7. 2002..These include limiting oxygen supplementation and light exposure, the use of antiinflammatory agents or antioxidants, and the use of room air in neonatal resuscitation... - Association of lipid peroxidation with antenatal betamethasone and oxygen radial disorders in preterm infantsBarry Weinberger
Division of Neonatology, Department of Pediatrics, UMDNJ Robert Wood Johnson Medical School, St Peter s University Hospital, New Brunswick, NJ 08901, USA
Biol Neonate 85:121-7. 2004..There is currently no effective way to quantify the risk for ORD. In this study, we analyzed the correlation of early urinary MDA and TBARS with prenatal betamethasone administration and with the development of ORD... - Evidence for interleukin-10-mediated inhibition of cyclo- oxygenase-2 expression and prostaglandin production in preterm human placentaNazeeh Hanna
Department of Pediatrics/Neonatology, UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ, USA
Am J Reprod Immunol 55:19-27. 2006..CONCLUSION: These results demonstrate the importance of IL-10 in countering inflammation associated with preterm labor, and suggest that term and preterm parturition may, in part, represent different conditions...
Research Grants
- ALTERED NEUTROPHIL APOPTOSIS /BRONCHOPULMONARY DYSPLASIABarry Weinberger; Fiscal Year: 2006..The identification of specific pathways mediating apoptosis that are altered in neonatal neutrophils may also suggest preventive therapeutic strategies. ..