Affiliation: New York University
- Tinkering with translation: protein synthesis in virus-infected cellsDerek Walsh
Department of Microbiology, New York University School of Medicine, New York, NY 10016, USA
Cold Spring Harb Perspect Biol 5:a012351. 2013..These demands have resulted in complex interactions between virus and host that exploit ostensibly virus-specific mechanisms and, at the same time, illuminate the functioning of the cellular protein synthesis apparatus...
- Activation of host translational control pathways by a viral developmental switchCarolina Arias
Department of Microbiology and NYU Cancer Institute, New York University School of Medicine, New York, New York, USA
PLoS Pathog 5:e1000334. 2009..Thus, herpesvirus reactivation from latency activates the host cap-dependent translation machinery, illustrating the importance of translational regulation in implementing new developmental instructions that drastically alter cell fate...
- Eukaryotic translation initiation factor 4F architectural alterations accompany translation initiation factor redistribution in poxvirus-infected cellsDerek Walsh
Department of Microbiology MSB214, NYU School of Medicine, 550 First Avenue, New York, NY 10016, USA
Mol Cell Biol 28:2648-58. 2008..Furthermore, it suggests that the subcellular distribution of eIF4F components may potentiate the complex assembly...
- Coupling 40S ribosome recruitment to modification of a cap-binding initiation factor by eIF3 subunit eDerek Walsh
Department of Microbiology, New York University School of Medicine, New York, New York 10016, USA
Genes Dev 28:835-40. 2014..This establishes a mechanism by which 40S ribosome loading imparts a phosphorylation mark on the cap-binding eIF4F complex that regulates selective mRNA translation and is synchronized by a specific eIF3 subunit. ..
- Assembly of an active translation initiation factor complex by a viral proteinDerek Walsh
Department of Microbiology and New York University Cancer Institute, New York University School of Medicine, New York, New York 10016, USA
Genes Dev 20:461-72. 2006....
- Regulation of the translation initiation factor eIF4F by multiple mechanisms in human cytomegalovirus-infected cellsDerek Walsh
Department of Microbiology, NYU Cancer Institute, New York, New York 10016, USA
J Virol 79:8057-64. 2005....