Research Topics
Genomes and GenesSpecies | Vesna TodorovicSummaryAffiliation: New York University School of Medicine Country: USA Publications
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Detail Information
Publications
Long form of latent TGF-β binding protein 1 (Ltbp1L) regulates cardiac valve developmentVesna Todorovic
Department of Cell Biology, NYU Langone Medical Center, New York, New York 10016, USA
Dev Dyn 240:176-87. 2011..We demonstrate that Ltbp1L is a major regulator of Tgf-β activity during valvulogenesis since its absence results in a perturbed Tgf-β pathway that causes all Ltbp1L(-/-) valvular defects...
LTBPs, more than just an escort serviceVesna Todorovic
Department of Cell Biology, NYU Langone Medical Center, New York, New York 10016, USA
J Cell Biochem 113:410-8. 2012..In the present article, we review recent advancements in the field and relate the complex roles of LTBP in development and homeostasis...
Long form of latent TGF-beta binding protein 1 (Ltbp1L) is essential for cardiac outflow tract septation and remodelingVesna Todorovic
Cell Biology Department, NYU School of Medicine, New York, NY 10016, USA
Development 134:3723-32. 2007..This phenotype reveals a crucial role for Ltbp1L and matrix as extracellular regulators of Tgf-beta activity in heart organogenesis...
Specificity of latent TGF-β binding protein (LTBP) incorporation into matrix: role of fibrillins and fibronectinLior Zilberberg
Department of Cell Biology, New York University Langone School of Medicine, New York, New York 10016, USA
J Cell Physiol 227:3828-36. 2012..Together, these data indicate that LTBP-3 and LTBP-4 association with the matrix depends on fibrillin-1 microfibrils, whereas LTBP-1 association depends on a fibronectin network...
Control of lung development by latent TGF-β binding proteinsBranka Dabovic
Department of Cell Biology, New York University Medical Center, New York, New York 10016, USA
J Cell Physiol 226:1499-509. 2011..Together these data indicate that LTBP-3 and -4 perform partially overlapping functions only in the lungs...
Perturbation of transforming growth factor (TGF)-beta1 association with latent TGF-beta binding protein yields inflammation and tumorsKeiji Yoshinaga
Department of Cell Biology, New York University Langone School of Medicine, New York, NY 10016, USA
Proc Natl Acad Sci U S A 105:18758-63. 2008..Moreover, although mechanisms exist to activate latent TGF-beta1 in the absence of LTBP, these mechanisms are not as efficient as those that use the latent complex containing LTBP...
Amino acid requirements for formation of the TGF-beta-latent TGF-beta binding protein complexesYan Chen
Department of Cell Biology, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
J Mol Biol 345:175-86. 2005....
Bone matrix to growth factors: location, location, locationDaniel B Rifkin
Department of Cell Biology, New York University School of Medicine, New York, NY 10016, USA
J Cell Biol 190:949-51. 2010..In this issue, Nistala et al. (2010. J. Cell Biol. doi: 10.1083/jcb.201003089) advance this concept by demonstrating how fibrillin-1 and -2 regulate TGF-β and bone morphogenetic protein (BMP) action during osteoblast maturation...
