Research Topics
| Eric A StoneSummaryAffiliation: New York University Country: USA Publications
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Detail Information
Publications
An anti-immobility effect of exogenous corticosterone in miceEric A Stone
Department of Psychiatry, New York University School of Medicine, 550 First Ave, New York, NY 10016, USA
Eur J Pharmacol 580:135-42. 2008..The hormone may act by suppression of neural activity in central stress circuits leading to a disinhibition of regions involved in active behavioral coping...
Evaluation of the repeated open-space swim model of depression in the mouseEric A Stone
Department of Psychiatry, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
Pharmacol Biochem Behav 91:190-5. 2008..It is concluded that repeated open-space swim represents a useful new model of depression in the mouse...- Central alpha1-adrenergic system in behavioral activity and depressionEric A Stone
New York University School of Medicine, Department of Psychiatry, NYU Medical Center, MHL HN510, 550 First Avenue, New York, NY 10016, USA
Biochem Pharmacol 73:1063-75. 2007.... - Role of locus coeruleus alpha1-adrenoceptors in motor activity in ratsEric A Stone
Department of Psychiatry, New York University School of Medicine, New York, New York 10016, USA
Synapse 54:164-72. 2004.... - Reduced evoked fos expression in activity-related brain regions in animal models of behavioral depressionEric A Stone
Department of Psychiatry, New York University School of Medicine, 550 First Ave, New York, NY 10016, United States
Prog Neuropsychopharmacol Biol Psychiatry 31:1196-207. 2007.... - Marked behavioral activation from inhibitory stimulation of locus coeruleus alpha1-adrenoceptors by a full agonistEric A Stone
Department of Psychiatry, New York University Langone School of Medicine, 550 First Ave, New York, NY 10016, USA
Brain Res 1291:21-31. 2009..It is hypothesized that the alpha(1)-receptors of the mouse LC are strongly activated by 6FNE and serve to potently inhibit its tonic or stress-induced activity which in turn disinhibits prepotent motivated behaviors... - Gross mapping of alpha1-adrenoceptors that regulate behavioral activation in the mouse brainEric A Stone
Department of Psychiatry, New York, NY 10016, USA
Behav Brain Res 152:167-75. 2004..It is hypothesized that brain motoric alpha1-receptors elicit behavioral activation by coordinately exciting several monoaminergic, motor and motivational systems... - Alpha(1)-adrenergic and alpha(2)-adrenergic balance in the dorsal pons and gross behavioral activity of mice in a novel environmentEric A Stone
Department of Psychiatry, New York University School of Medicine, 550 First Ave, New York, NY, 10016, USA
Psychopharmacology (Berl) 183:127-32. 2005..This condition may be relevant to inactive states seen after stress or during depressive illness... - A final common pathway for depression? Progress toward a general conceptual frameworkEric A Stone
Department of Psychiatry, New York University School of Medicine, New York, NY 10016, USA
Neurosci Biobehav Rev 32:508-24. 2008.... 
Antidepressant-like action of intracerebral 6-fluoronorepinephrine, a selective full α-adrenoceptor agonistEric A Stone
Department of Psychiatry, New York University Langone School of Medicine, New York, NY 10016, USA
Int J Neuropsychopharmacol 14:319-31. 2011..It is concluded that 6FNE elicits a rapid and effective antidepressant and anti-stress response that may compare favourably with available antidepressants...- Possible dopaminergic stimulation of locus coeruleus alpha1-adrenoceptors involved in behavioral activationYan Lin
Department of Psychiatry, New York University School of Medicine, New York, New York 10016, USA
Synapse 62:516-23. 2008..These results indicate that DA is a candidate as an endogenous agonist for behaviorally activating LC alpha(1)-receptors and may play a role in the activation of this nucleus by novel surroundings... - Further evidence for an immediate antidepressant action of intracerebral drug administration in a model of chronic depressionYan Lin
New York University Langone School of Medicine, Department of Psychiatry, 550 First Ave, New York, NY, USA
Int J Neuropsychopharmacol 14:691-6. 2011..The results suggest that stress-induced alterations of regional drug uptake or metabolism in the CNS may contribute to the therapeutic lag for antidepressants and other compounds in disorders with high distress... - Immobility from administration of the alpha1-adrenergic antagonist, terazosin, in the IVth ventricle in ratsEric A Stone
Department of Psychiatry, Psychiatry MHL HN510, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
Neurosci Lett 353:231-3. 2003..The results could not be explained by sedation. It is concluded that central alpha1-adrenoceptors are essential for behavioral activation in rats as in mice... - Depressive behavior in mice due to immune stimulation is accompanied by reduced neural activity in brain regions involved in positively motivated behaviorEric A Stone
Department of Psychiatry, New York University School of Medicine, New York, New York 10016, USA
Biol Psychiatry 60:803-11. 2006.... - Role of alpha(1)-adrenoceptors of the locus coeruleus in self-stimulation of the medial forebrain bundleYan Lin
Department of Psychiatry, New York University School of Medicine, New York University Medical Center, New York, NY 10016, USA
Neuropsychopharmacology 32:835-41. 2007..It is concluded that LC alpha(1)-adrenoceptors are involved both in reward/motivational processes and operant response elaboration which are postulated to work together to facilitate goal attainment... - Role of CNS alpha1-adrenoceptor activity in central fos responses to noveltyEric A Stone
Department of Psychiatry, New York University School of Medicine, New York, New York 10016, USA
Synapse 59:299-307. 2006.... - Evidence of roles of central alpha1-adrenoceptors and epinephrine in orexin A-induced hyperactivity in miceEric A Stone
Department of Psychiatry, New York University School of Medicine, MHL HN510, NYU Med Centre, 550 First Avenue, New York, NY 10016, USA
Neurosci Lett 381:325-8. 2005..It is concluded that central alpha1-adrenoceptor activity, presumably caused by epinephrine release, is necessary for the gross behavioral activation produced by orexin A... - The role of the central noradrenergic system in behavioral inhibitionEric A Stone
Department of Psychiatry, New York University Langone School of Medicine, 550 First Ave, New York, NY 10016, USA
Brain Res Rev 67:193-208. 2011..A similar mechanism may underlie the ability of the noradrenergic system to suppress seizure activity suggesting that inhibition of the spread of neural activation may be a unifying function... - Emerging evidence for a central epinephrine-innervated alpha 1-adrenergic system that regulates behavioral activation and is impaired in depressionEric A Stone
Departments of Psychiatry and Neurology, New York University School of Medicine, NYU Medical Center, 550 First Avenue, New York, NY 10016, USA
Neuropsychopharmacology 28:1387-99. 2003..This "EPI-alpha(1) system" may therefore represent a new target system for this disorder... - Participation of brainstem monoaminergic nuclei in behavioral depressionYan Lin
Department of Psychiatry, New York University Langone School of Medicine, 550 First Ave, New York, NY 10016, United States
Pharmacol Biochem Behav 100:330-9. 2011.... - Rate-dependent behavioral effects of stimulation of central motoric alpha(1)-adrenoceptors: hypothesized relation to depolarization blockadeEric A Stone
Department of Psychiatry MHL HN510, NYU Med Ctr, 550 First Ave, New York, NY 10016, USA
Psychopharmacology (Berl) 178:109-14. 2005..The purpose of this review is to clarify how central alpha(1)-adrenoceptors control behavioral activity under varying conditions of activity and stress... - Open-space forced swim model of depression for miceEric A Stone
Department of Psychiatry, New York University Langone School of Medicine, New York, New York, USA
Curr Protoc Neurosci . 2011..Moreover, since it utilizes a greater swimming area than the traditional (Porsolt) method it can be used to study interactions of depressive behavior with behavioral flexibility and perseveration... - Role of brain alpha 1B-adrenoceptors in modafinil-induced behavioral activityEric A Stone
New York University School of Medicine, New York, New York 10016, USA
Synapse 46:269-70. 2002..These studies show that either central pharmacological blockade or genetic ablation of alpha(1B)-adrenoceptors markedly attenuates the behavioral activation caused by modafinil, implicating these receptors in the drug's action... - Role of epinephrine stimulation of CNS alpha1-adrenoceptors in motor activity in miceEric A Stone
Department of Psychiatry, New York University School of Medicine, New York, New York 10016, USA
Synapse 49:67-76. 2003.... - Stress-induced subsensitivity to modafinil and its prevention by corticosteroidsEric A Stone
Department of Psychiatry, TH HN510, School of Medicine, New York University Medical Center, 550 First Avenue, New York, NY 10016, USA
Pharmacol Biochem Behav 73:971-8. 2002.... - A final common pathway for depression: implications for therapyEric A Stone
Psychiatry, MHL HN510, NYU Medical Centre, New York, NY 10016, USA
Expert Opin Ther Targets 11:1019-32. 2007.... - Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot projectEwan Birney
Nature 447:799-816. 2007..Together, these studies are defining a path for pursuit of a more comprehensive characterization of human genome function... - Visual analog scales for assessment of thermal perception in different environmentsGloria R Leon
Department of Psychology, Laboratory for Health and Human Performance in Extreme Environments, University of Minnesota, Elliott Hall, 75 E River Rd, Minneapolis, MN 55455, USA
Aviat Space Environ Med 79:784-6. 2008..At present, there is an increasing use of visual analog scales (VAS) to assess whole body and body region thermal perceptions in laboratory and other thermal environments...