Research Topics
| N SouayahSummaryAffiliation: New Jersey Country: USA Publications
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Publications
Guillain-Barré syndrome after influenza vaccination in the United States, a report from the CDC/FDA vaccine adverse event reporting system (1990-2009)Nizar Souayah
Department of Neurology, University of Medicine and Dentistry of New Jersey, Newark, USA
J Clin Neuromuscul Dis 14:66-71. 2012..To determine the rate of Guillain-Barré syndrome (GBS) after administration of influenza vaccine in the United States and to provide further information about the characteristics and temporal profile of these incidents...
Analysis of data from the CDC/FDA vaccine adverse event reporting system (1990-2009) on Guillain-Barre syndrome after hepatitis vaccination in the USANizar Souayah
Department of Neurology, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103, USA
J Clin Neurosci 19:1089-92. 2012..Nonetheless, the low incidence of hepatitis vaccine-associated GBS, and the dramatic incidence reduction of hepatitis and its complications after vaccination, support the current guidelines for vaccination...
Trends in outcome and hospitalization charges of adult patients admitted with botulism in the United StatesNizar Souayah
Department of Neurology, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103, USA
Neuroepidemiology 38:233-6. 2012..To assess the impact of new therapeutic strategies on outcomes and hospitalization charges among adult patients with botulism in the United States...
Guillain-Barré syndrome after H1N1 vaccination in the United States: a report using the CDC/FDA Vaccine Adverse Event Reporting System (2009)Nizar Souayah
Department of Neurology, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103, USA
Neuroepidemiology 38:227-32. 2012..The objective of this report is to study the occurrence and characteristics of GBS after H1N1 vaccine administration in the United States in 2009...
The safety profile of home infusion of intravenous immunoglobulin in patients with neuroimmunologic disordersNizar Souayah
Department of Neurology, University of Medicine and Dentistry of New Jersey, Newark, NJ, USA
J Clin Neuromuscul Dis 12:S1-10. 2011..To assess the overall safety of high-dose intravenous immunoglobulin (IG) products used to treat patients with neuroimmunological disorders in a supervised home-based setting...
Defective neuromuscular transmission in the SOD1 G93A transgenic mouse improves after administration of human umbilical cord blood cellsNizar Souayah
Department of Neurology and Neurosciences, New Jersey Medical School UMDNJ, 185 South Orange Avenue, Newark, NJ 07103 2714, USA
Stem Cell Rev 8:224-8. 2012..Testing PNMT in the SOD1(G93A) mouse model could be used as a simple in vitro protocol to detect a positive cellular response to therapeutic interventions in ALS...
Increased expression and local accumulation of the prion protein, Alzheimer Aβ peptides, superoxide dismutase 1, and nitric oxide synthases 1 & 2 in muscle in a rabbit model of diabetesClaudine L Bitel
Department of Pharmacology and Physiology, UMDNJ New Jersey Medical School, 185 S, Orange Ave, Newark, NJ 07103, USA
BMC Physiol 10:18. 2010..This wild-type rabbit model includes systemic physiological expression of human-like Alzheimer precursor proteins and Aβ peptides that are considered key in Alzheimer protein studies...
Guillain-Barré syndrome after Gardasil vaccination: data from Vaccine Adverse Event Reporting System 2006-2009Nizar Souayah
Department of Neurology, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103, USA
Vaccine 29:886-9. 2011..Further prospective active surveillance for accurate ascertainment and identification of high-risk groups of GBS after Gardasil vaccination is warranted...
Neurosarcoidosis presenting as an anterior horn syndromeNizar Souayah
Department of Neurosciences, UMDNJ New Jersey Medical School, Newark, NJ 07101 1709, USA
J Neuroimmunol 225:132-6. 2010..We hypothesize that meningeal granulomatous inflammation compressed the exiting anterior roots which resulted in motor dysfunction with preservation of peripheral sensory fibers...
A prospective double-blind, placebo-controlled study of thalidomide sensory symptoms in an elderly population with age-related macular degenerationNizar Souayah
Department of Neurology, New Jersey Medical School, 90 Bergen Street, DOC 8100, Newark, New Jersey 07101, USA
J Clin Neurosci 17:571-3. 2010..The SS occurred shortly after thalidomide was introduced and we concluded that older patients with macular degeneration should be carefully screened for risk factors of peripheral neuropathy before thalidomide is used in their treatment...
Asymmetric phenotype associated with rare myelin protein zero mutationNizar Souayah
Department of Neurology and Neurosciences, University of Medicine and Dentistry of New Jersey, Newark, NJ, USA
J Clin Neuromuscul Dis 11:110-3. 2010..The patient's paternal grandfather had high-arched feet and hearing loss. We conclude that ARG98HIS MPZ mutation may cause hereditary and relatively mild and asymmetric demyelinating sensorimotor polyneuropathy...
Small fiber neuropathy following vaccination for rabies, varicella or Lyme diseaseNizar Souayah
Department of Neurology, New Jersey Medical School, 90 Bergen Street, DOC 8100, Newark, NJ 07103, United States
Vaccine 27:7322-5. 2009..All patients' symptoms have improved, but persist. We conclude that an acute or subacute, post-vaccination small fiber neuropathy may occur and follow a chronic course...
Guillain-Barré syndrome after vaccination in United States: data from the Centers for Disease Control and Prevention/Food and Drug Administration Vaccine Adverse Event Reporting System (1990-2005)Nizar Souayah
Epidemiological and Outcomes Research Division, Zeenat Qureshi Stroke Research Center, Department of Neurology, University of Medicine and Dentistry of New Jersey, Newark, NJ, USA
J Clin Neuromuscul Dis 11:1-6. 2009..There are isolated reports of Guillain-Barré syndrome (GBS) after receiving vaccination...
Motor unit number estimate as a predictor of motor dysfunction in an animal model of type 1 diabetesNizar Souayah
Departments of Neuroscience, New Jersey Medical School University of Medicine and Dentistry of New Jersey, Newark, NJ 07101 1709, USA
Am J Physiol Endocrinol Metab 297:E602-8. 2009..Therefore, trials of interventions to prevent motor axon dysfunction in diabetic neuropathy should be administered at early stages of the disorder...
Effect of intravenous immunoglobulin on cerebellar ataxia and neuropathic pain associated with celiac diseaseN Souayah
Department of Neurology, New Jersey Medical School, Newark, NJ, USA
Eur J Neurol 15:1300-3. 2008..Cerebellar syndrome and small fiber neuropathy may complicate celiac disease (CD) and may be resistant to a strict gluten-free diet...
Reductions in motor unit number estimates (MUNE) precede motor neuron loss in the plasma membrane calcium ATPase 2 (PMCA2)-heterozygous miceNizar Souayah
Department of Neurology and Neuroscience, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103, USA
Exp Neurol 214:341-6. 2008....
National trends in hospital outcomes among patients with Guillain-Barré syndrome requiring mechanical ventilationNizar Souayah
Department of Neurology, University of Medicine and Dentistry of New Jersey, Newark, NJ, USA
J Clin Neuromuscul Dis 10:24-8. 2008..This outcome may be more reflective of changing patterns of hospitalization rather than relatively futility of new treatments...
Isolated severe vasculitic neuropathy revealing sarcoidosisNizar Souayah
Department of Neurosciences, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ, USA
Lancet Neurol 7:756-60. 2008
Relapsing Guillain Barré Syndrome and nephrotic syndrome secondary to focal segmental glomerulosclerosisNizar Souayah
Department of Neurology and Neurosciences, University of Medicine and Dentistry of New Jersey, Newark, NJ, USA
J Neurol Sci 270:184-8. 2008..Renal biopsy revealed focal segmental glomerulosclerosis (FSGS). He responded to plasmapheresis and corticosteroids with simultaneous recovery of his GBS and NS, suggesting a common pathogenesis of the two conditions...
Myotonic dystrophy type 1 presenting with ventilatory failureNizar Souayah
Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA
J Clin Neuromuscul Dis 9:252-5. 2007..To report a series of patients with adult onset myotonic dystrophy type 1 (DM1) in whom the presenting symptom was ventilatory failure...
Elevated anti-sulfatide antibodies in Guillain-Barré syndrome in T cell depleted at end-stage AIDSNizar Souayah
Department of Neurology and Neuroscience, UMDNJ New Jersey Medical School, Newark, NJ 07103, United States
J Neuroimmunol 188:143-5. 2007..The data suggest that elevated levels of anti-sulfatide antibodies may play a role in the pathogenesis of GBS in this patient, although a direct neurotropic effect of HIV virus cannot be excluded...
Insights into neurologic localization by Rhazes, a medieval Islamic physicianNizar Souayah
Multiple Sclerosis Institute, Philadelphia, PA, USA
Neurology 65:125-8. 2005..Rhazes was a pioneer in applied neuroanatomy. He combined a knowledge of cranial and spinal cord nerve anatomy with an insightful use of clinical information to localize lesions in the nervous system...
Acute sensory neuronopathy as the presenting symptom of Sjögren's syndromeNizar Souayah
Neurology Department, New Jersey Medical School, Newark, NJ 07101, USA
J Clin Neurosci 13:862-5. 2006..Lip biopsy showed findings consistent with SS. Sural nerve biopsy showed severe axonal loss. The patient showed modest improvement with immunosuppressive therapies...
Severe botulism after focal injection of botulinum toxinN Souayah
Departments of Neurology, New Jersey Medical School of the University of Medicine and Dentistry of New Jersey, Newark, NJ 07101, USA
Neurology 67:1855-6. 2006..Electrophysiologic findings demonstrated complete denervation with complete electrical silence. She had a lengthy recovery but was able to ambulate by discharge...
Guillain-Barre syndrome after vaccination in United States a report from the CDC/FDA Vaccine Adverse Event Reporting SystemNizar Souayah
Epidemiological and Outcomes Research Division, Zeenat Qureshi Stroke Research Center, Department of Medicine, University of Medicine and Dentistry of New Jersey, 90 Bergen Street, DOC 8100, Newark, NJ 07103, United States
Vaccine 25:5253-5. 2007..We conclude that vaccines other than influenza vaccine can be associated with GBS...
Guillain-Barré syndrome triggered by influenza vaccination in a recipient of liver transplant on FK506Joon-Shik Moon
Department of Neurology, UMDNJ-New Jersey Medical School, Newark, NJ 07101, USA
Liver Transpl 12:1537-9. 2006..Despite treatment with intravenous immunoglobulin, the patient expired. GBS occurred despite downregulation of T cells by FK506, suggesting that humoral dysfunction might be the predominant mechanism of GBS in this report...
Lumbosacral magnetic root stimulation in lumbar plexopathyNizar Souayah
Department of Neurology and Neurosciences, New Jersey Medical School, Newark, New Jersey, USA
Am J Phys Med Rehabil 85:858-61. 2006..To our knowledge, this is the first report of magnetic root stimulation in assessment of lumbosacral plexus dysfunction in retroperitoneal hematoma...
Rare myelin protein zero sequence variant in late onset CMT1BNizar Souayah
Department of Neurology, Department, New Jersey Medical School, 90 Bergen Street DOC 8128, Newark, NJ 071011, USA
J Neurol Sci 263:177-9. 2007..In patients tested for possible CMT, the frequency of MPZ His-Pro codon 10 substitutions was 0.11% (27 of 24,076 alleles)...
Systemic treatment of cerebral cortex lesions in rats with a new secreted phospholipase A2 inhibitorTimothy J Cunningham
Department of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, Pennsylvania 19129, USA
J Neurotrauma 21:1683-91. 2004....
