Ellen Shapiro

Summary

Affiliation: New York University School of Medicine
Country: USA

Publications

  1. doi request reprint Clinical implications of genitourinary embryology
    Ellen Shapiro
    Department of Urology, New York University School of Medicine, New York, New York 10016, USA
    Curr Opin Urol 19:427-33. 2009
  2. pmc Bmp7 functions via a polarity mechanism to promote cloacal septation
    Kun Xu
    Department of Urology, School of Medicine, New York University, New York, New York, United States of America
    PLoS ONE 7:e29372. 2012
  3. pmc Differentiation of the ductal epithelium and smooth muscle in the prostate gland are regulated by the Notch/PTEN-dependent mechanism
    Xinyu Wu
    Department of Urology, New York University School of Medicine, 423 East 23rd Street, New York, NY 10010, USA
    Dev Biol 356:337-49. 2011
  4. pmc The Stress-response protein prostate-associated gene 4, interacts with c-Jun and potentiates its transactivation
    Krithika Rajagopalan
    Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Biochim Biophys Acta 1842:154-63. 2014
  5. pmc LEF1 identifies androgen-independent epithelium in the developing prostate
    Xinyu Wu
    Department of Urology, New York University School of Medicine, 423 East 23rd Street, New York, New York 10010, USA
    Mol Endocrinol 25:1018-26. 2011
  6. pmc Urothelial tumor initiation requires deregulation of multiple signaling pathways: implications in target-based therapies
    Haiping Zhou
    Department of Urology, NYU Cancer Institute, New York University School of Medicine, New York, NY 10016, USA
    Carcinogenesis 33:770-80. 2012
  7. pmc Bmp7 expression and null phenotype in the urogenital system suggest a role in re-organization of the urethral epithelium
    Xinyu Wu
    Department of Urology, New York University School of Medicine, 423 East 23rd Street 18064 South, New York, NY 10010, USA
    Gene Expr Patterns 9:224-30. 2009

Collaborators

Detail Information

Publications7

  1. doi request reprint Clinical implications of genitourinary embryology
    Ellen Shapiro
    Department of Urology, New York University School of Medicine, New York, New York 10016, USA
    Curr Opin Urol 19:427-33. 2009
    ..This review focuses on recent advances in molecular embryology of the upper and lower urinary tract with an emphasis on clinical correlation in order to gain a better understanding for the mechanism of congenital anomalies...
  2. pmc Bmp7 functions via a polarity mechanism to promote cloacal septation
    Kun Xu
    Department of Urology, School of Medicine, New York University, New York, New York, United States of America
    PLoS ONE 7:e29372. 2012
    ..Defects in cloacal development are very common and present clinically as a rectourethral fistula in about 1 in 5,000 live human births. Yet, the cellular mechanisms of cloacal septation remain poorly understood...
  3. pmc Differentiation of the ductal epithelium and smooth muscle in the prostate gland are regulated by the Notch/PTEN-dependent mechanism
    Xinyu Wu
    Department of Urology, New York University School of Medicine, 423 East 23rd Street, New York, NY 10010, USA
    Dev Biol 356:337-49. 2011
    ..In addition, we found that both positive and negative modulation of Notch signaling results in abnormal organization of the prostate tissue, and can contribute to prostate disease in the adult organ...
  4. pmc The Stress-response protein prostate-associated gene 4, interacts with c-Jun and potentiates its transactivation
    Krithika Rajagopalan
    Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Biochim Biophys Acta 1842:154-63. 2014
    ..To our knowledge, this is the first report demonstrating crosstalk between a CTA and a proto-oncogene. Disrupting PAGE4/c-Jun interactions using small molecules may represent a novel therapeutic strategy for PCa. ..
  5. pmc LEF1 identifies androgen-independent epithelium in the developing prostate
    Xinyu Wu
    Department of Urology, New York University School of Medicine, 423 East 23rd Street, New York, New York 10010, USA
    Mol Endocrinol 25:1018-26. 2011
    ..We conclude that Wnt/Lef1 activity identifies an androgen-independent population of prostate progenitors, which is important for embryonic development and organ maintenance and regeneration in the adult...
  6. pmc Urothelial tumor initiation requires deregulation of multiple signaling pathways: implications in target-based therapies
    Haiping Zhou
    Department of Urology, NYU Cancer Institute, New York University School of Medicine, New York, NY 10016, USA
    Carcinogenesis 33:770-80. 2012
    ....
  7. pmc Bmp7 expression and null phenotype in the urogenital system suggest a role in re-organization of the urethral epithelium
    Xinyu Wu
    Department of Urology, New York University School of Medicine, 423 East 23rd Street 18064 South, New York, NY 10010, USA
    Gene Expr Patterns 9:224-30. 2009
    ..Together, our analysis of Bmp7 expression and the null phenotype, indicates that Bmp7 may play an important role in re-organization of the epithelium during cloacal septation and morphogenesis of the genital tubercle...