Research Topics
Genomes and GenesSpecies | D B SeiferSummaryAffiliation: New Jersey Country: USA Publications
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Publications
Women with declining ovarian reserve may demonstrate a decrease in day 3 serum inhibin B before a rise in day 3 follicle-stimulating hormoneD B Seifer
Center for Reproduction, Endocrinology and Fertility, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick 08902, USA
Fertil Steril 72:63-5. 1999..To test the hypothesis that women with declining ovarian reserve may demonstrate a decrease in day 3 serum inhibin B levels before a rise in day 3 serum FSH levels...
Immunocytochemical evidence for the presence and location of the neurotrophin-Trk receptor family in adult human preovulatory ovarian folliclesDavid B Seifer
Division of Reproductive Endocrinology and Infertility, Department of Obstetrics, Gynecology and Reproductive Sciences, UMDNJ Robert Wood Johnson Medical School, New Brunswick, NJ, USA
Am J Obstet Gynecol 194:1129-34; discussion 1134-6. 2006..This study was undertaken to evaluate the presence or absence of neurotrophins and their respective receptors within adult human preovulatory follicles...
Ovarian brain-derived neurotrophic factor is present in follicular fluid from normally cycling womenDavid B Seifer
Department of Obstetrics, Gynecology and Reproductive Sciences, Division of Reproductive Endocrinology and Infertility, UMDNJ-Robert Wood Johnson Medical School, New Brunswick, New Jersey 08901, USA
Fertil Steril 79:451-2. 2003
Mitochondrial deletions in luteinized granulosa cells as a function of age in women undergoing in vitro fertilizationDavid B Seifer
Department of Obstetrics, Gynecology and Reproductive Sciences, Division of Reproductive Endocrinology and Infertility, UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey 08901, USA
Fertil Steril 78:1046-8. 2002..To test the hypothesis that mitochondrial DNA (mtDNA) deletions are more prevalent in granulosa cells from women of advanced reproductive age than from younger women undergoing IVF...
Neurotrophin-4/5 and neurotrophin-3 are present within the human ovarian follicle but appear to have different paracrine/autocrine functionsDavid B Seifer
Department of Obstetrics, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick, New Jersey 08901, USA
J Clin Endocrinol Metab 87:4569-71. 2002..These data suggest that NT-4/5, like BDNF, promotes oocyte nuclear maturation. In contrast, NT-3 does not promote oocyte maturation but may contribute to follicle-oocyte maturation by mechanisms not yet identified...
Do women with unexplained recurrent pregnancy loss have higher day 3 serum FSH and estradiol values?S W Trout
Division of Reproductive Endocrinology and Infertility, UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA
Fertil Steril 74:335-7. 2000..To determine the potential role of diminished ovarian reserve in unexplained habitual abortion...
Contribution of diminished ovarian reserve to hypofertility associated with endometriosisD L Hock
Department of Obstetrics, Gynecology and Reproductive Sciences, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA
J Reprod Med 46:7-10. 2001..This observation is consistent with progressive loss of ovarian reserve in women with increasing stages of endometriosis independent of age...
Practice patterns among board-certified reproductive endocrinologists regarding high-order multiple gestations: a united states national surveyDoreen L Hock
Reproductive Medicine Associates of New Jersey, Somerset, USA
Obstet Gynecol 99:763-70. 2002..Given the inconsistent practice patterns, a multifaceted educational approach may provide an opportunity to reduce the incidence of high-order multiple gestations and their sequelae...
Biologic markers of ovarian reserve and reproductive aging: application in a cohort study of HIV infection in womenDavid B Seifer
Maimonides Medical Center, Department of Obstetrics and Gynecology, Brooklyn, New York, USA
Fertil Steril 88:1645-52. 2007..To determine whether HIV infection influences early follicular MIS levels, an early marker of ovarian aging...
Serum müllerian-inhibiting substance in Down's syndrome pregnanciesDavid B Seifer
Maimonides Medical Center, Brooklyn, New York, NY, USA
Hum Reprod 22:1017-20. 2007..To examine whether maternal serum levels of müllerian-inhibiting substance (MIS) differ in Down's syndrome and unaffected pregnancies...
Metformin reduces serum mullerian-inhibiting substance levels in women with polycystic ovary syndrome after protracted treatmentRichard Fleming
University Department of Obstetrics and Gynaecology, Royal Infirmary, Glasgow, United Kingdom
Fertil Steril 83:130-6. 2005..Assessment of ovarian responses to metformin treatment in obese women with polycystic ovary syndrome (PCOS)...
Serum antimüllerian hormone/müllerian-inhibiting substance appears to be a more discriminatory marker of assisted reproductive technology outcome than follicle-stimulating hormone, inhibin B, or estradiolAndré Hazout
ART Unit Eylau la Muette, Clinic La Muette, Paris, France
Fertil Steril 82:1323-9. 2004..To test the hypothesis that the concentration of early follicular phase serum antimullerian hormone (AMH) or mullerian-inhibiting substance (MIS) is a useful marker of ovarian response and assisted reproductive technology (ART) outcome...
Effect of gonadotropins on brain-derived neurotrophic factor secretion by human follicular cumulus cellsBo Feng
Fertil Steril 80:658-9. 2003
In vitro fertilization in the older patientSeth G Derman
Division of Reproductive Endocrinology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick, NJ 08901, USA
Curr Womens Health Rep 3:375-83. 2003....
Brain-derived neurotrophic factor: a novel human ovarian follicular proteinDavid B Seifer
Department of Obstetrics, Gynecology and Reproductive Sciences, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick, New Jersey 08901, USA
J Clin Endocrinol Metab 87:655-9. 2002..These experiments demonstrate for the first time the presence and secretion of BDNF from follicular cells in the human ovary and suggest a possible role for BDNF in the regulation and modulation of oocyte maturation...
Early follicular serum müllerian-inhibiting substance levels are associated with ovarian response during assisted reproductive technology cyclesDavid B Seifer
Department of Obstetrics, Gynecology and Reproductive Sciences, Division of Reproductive Endocrinology and Infertility, UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey 08901, USA
Fertil Steril 77:468-71. 2002....
DNA microarray analysis of the expression profiles of luteinized granulosa cells as a function of ovarian reserveKhew Voon Chin
The Cancer Institute of New Jersey, UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey 08901, USA
Fertil Steril 77:1214-8. 2002..To examine the expression profiles of luteinized granulosa cells isolated from women with normal or diminished ovarian reserve undergoing in vitro fertilization...
Mullerian Inhibiting Substance is an ovarian growth factor of emerging clinical significanceDavid B Seifer
Department of Obstetrics and Gynecology, Maimonides Medical Center, Brooklyn, New York 11228, USA
Fertil Steril 88:539-46. 2007..To examine Mullerian Inhibiting Substance (MIS) as an emerging diagnostic marker of ovarian function...
Social concerns of women undergoing infertility treatmentPeter S Finamore
Department of Obstetrics, Gynecology and Reproductive Sciences, UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA
Fertil Steril 88:817-21. 2007..We hypothesize that, in certain women, disclosure may lower stress, and therefore increase success rate of in vitro fertilization...
