N Schlesinger

Summary

Affiliation: New Jersey
Country: USA

Publications

  1. ncbi request reprint A survey of current evaluation and treatment of gout
    Naomi Schlesinger
    Department of Medicine, The School of Public Health, University of Medicine and Dentistry of New Jersey, New Brunswick, New Jersey 08903 0019, USA
    J Rheumatol 33:2050-2. 2006
  2. doi request reprint Canakinumab for acute gouty arthritis in patients with limited treatment options: results from two randomised, multicentre, active-controlled, double-blind trials and their initial extensions
    Naomi Schlesinger
    Division of Rheumatology, Department of Medicine, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick, NJ 08901, USA
    Ann Rheum Dis 71:1839-48. 2012
  3. doi request reprint Treatment of chronic gouty arthritis: it is not just about urate-lowering therapy
    Naomi Schlesinger
    Division of Rheumatology, Department of Medicine, UMDNJ RWJMS, New Brunswick, NJ, USA
    Semin Arthritis Rheum 42:155-65. 2012
  4. doi request reprint Canakinumab in gout
    Naomi Schlesinger
    Division of Rheumatology, Department of Medicine, UMDNJ RWJMS, MEB 468, PO Box 19, New Brunswick, NJ 08903 0019, USA
    Expert Opin Biol Ther 12:1265-75. 2012
  5. pmc Imaging of gout: findings and utility
    Fernando Perez-Ruiz
    Rheumatology Division, Hospital de Cruces, Baracaldo, Vizcaya, Spain
    Arthritis Res Ther 11:232. 2009
  6. ncbi request reprint Does acute synovitis (pseudogout) occur in patients with chronic pyrophosphate arthropathy (pseudo-osteoarthritis)?
    N Schlesinger
    Division of Rheumatology, Department of Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, NJ 08903 0019, USA
    Clin Exp Rheumatol 27:940-4. 2009
  7. doi request reprint Gout--what are the treatment options?
    Naomi Schlesinger
    Division of Rheumatology Department of Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, NJ 08903 0019, USA
    Expert Opin Pharmacother 10:1319-28. 2009
  8. doi request reprint Serum urate during acute gout
    Naomi Schlesinger
    Department of Medicine, Division of Rheumatology, UMDNJ Robert Wood Johnson Medical School, MEB 474 PO Box 19, New Brunswick, NJ 08903 0019, USA
    J Rheumatol 36:1287-9. 2009
  9. ncbi request reprint Overview of the management of acute gout and the role of adrenocorticotropic hormone
    Naomi Schlesinger
    Department of Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903 0019, USA
    Drugs 68:407-15. 2008
  10. ncbi request reprint Diagnosis of gout
    N Schlesinger
    Division of Rheumatology, Department of Medicine, UMDNJ Robert Wood Johnson Medical School, One Robert Wood Johnson Pl, New Brunswick, NJ 08903 0019, USA
    Minerva Med 98:759-67. 2007

Detail Information

Publications39

  1. ncbi request reprint A survey of current evaluation and treatment of gout
    Naomi Schlesinger
    Department of Medicine, The School of Public Health, University of Medicine and Dentistry of New Jersey, New Brunswick, New Jersey 08903 0019, USA
    J Rheumatol 33:2050-2. 2006
    ..To record diagnostic and treatment approaches to gouty arthritis among US rheumatologists...
  2. doi request reprint Canakinumab for acute gouty arthritis in patients with limited treatment options: results from two randomised, multicentre, active-controlled, double-blind trials and their initial extensions
    Naomi Schlesinger
    Division of Rheumatology, Department of Medicine, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick, NJ 08901, USA
    Ann Rheum Dis 71:1839-48. 2012
    ..Core study co-primary endpoints were pain intensity 72 h postdose (0-100 mm visual analogue scale and time to first new flare...
  3. doi request reprint Treatment of chronic gouty arthritis: it is not just about urate-lowering therapy
    Naomi Schlesinger
    Division of Rheumatology, Department of Medicine, UMDNJ RWJMS, New Brunswick, NJ, USA
    Semin Arthritis Rheum 42:155-65. 2012
    ....
  4. doi request reprint Canakinumab in gout
    Naomi Schlesinger
    Division of Rheumatology, Department of Medicine, UMDNJ RWJMS, MEB 468, PO Box 19, New Brunswick, NJ 08903 0019, USA
    Expert Opin Biol Ther 12:1265-75. 2012
    ..Additional treatment options are therefore needed for this population with difficult-to-treat gout...
  5. pmc Imaging of gout: findings and utility
    Fernando Perez-Ruiz
    Rheumatology Division, Hospital de Cruces, Baracaldo, Vizcaya, Spain
    Arthritis Res Ther 11:232. 2009
    ....
  6. ncbi request reprint Does acute synovitis (pseudogout) occur in patients with chronic pyrophosphate arthropathy (pseudo-osteoarthritis)?
    N Schlesinger
    Division of Rheumatology, Department of Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, NJ 08903 0019, USA
    Clin Exp Rheumatol 27:940-4. 2009
    ..The two most common are: acute synovitis (pseudogout) and chronic pyrophosphate arthropathy ("pseudo-osteoarthritis"). We have conducted a study to examine whether these are overlapping syndromes...
  7. doi request reprint Gout--what are the treatment options?
    Naomi Schlesinger
    Division of Rheumatology Department of Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, NJ 08903 0019, USA
    Expert Opin Pharmacother 10:1319-28. 2009
    ..It is important to note that inappropriate use of medications as opposed to an apparent refractoriness to available therapies is not uncommon...
  8. doi request reprint Serum urate during acute gout
    Naomi Schlesinger
    Department of Medicine, Division of Rheumatology, UMDNJ Robert Wood Johnson Medical School, MEB 474 PO Box 19, New Brunswick, NJ 08903 0019, USA
    J Rheumatol 36:1287-9. 2009
    ..To study the frequency of normal serum urate (SU) levels during acute gout in the largest studies of acute gout treatment to date...
  9. ncbi request reprint Overview of the management of acute gout and the role of adrenocorticotropic hormone
    Naomi Schlesinger
    Department of Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903 0019, USA
    Drugs 68:407-15. 2008
    ..Hopefully, this will lead to renewed interest in corticotropin as a treatment for acute gout...
  10. ncbi request reprint Diagnosis of gout
    N Schlesinger
    Division of Rheumatology, Department of Medicine, UMDNJ Robert Wood Johnson Medical School, One Robert Wood Johnson Pl, New Brunswick, NJ 08903 0019, USA
    Minerva Med 98:759-67. 2007
    ..This paper presents an overview of the various classification criteria, clinical presentations, laboratory and radiological studies needed to make the diagnosis of gout...
  11. doi request reprint Diagnosing and treating gout: a review to aid primary care physicians
    Naomi Schlesinger
    Department of Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA
    Postgrad Med 122:157-61. 2010
    ..The aim of this review is to aid generalist physicians in diagnosing and treating gout. A case report example is presented to highlight some of the problems in diagnosing and treating gout. Practical practice points are also highlighted...
  12. doi request reprint New agents for the treatment of gout and hyperuricemia: febuxostat, puricase, and beyond
    Naomi Schlesinger
    Division of Rheumatology, Department of Medicine, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, One Robert Wood Johnson Place, New Brunswick, NJ 08903, USA
    Curr Rheumatol Rep 12:130-4. 2010
    ..Several other pharmaceutical companies are also conducting clinical trials to test new drugs for acute and chronic gout. This article reviews new drugs and drugs in development in the management of acute and chronic gout...
  13. doi request reprint The pathogenesis of bone erosions in gouty arthritis
    Naomi Schlesinger
    Department of Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA
    Ann Rheum Dis 69:1907-12. 2010
    ..It is the tophus eroding the underlying bone that is pivotal for the development of bone erosions in gouty arthritis...
  14. ncbi request reprint Pegloticase
    Naomi Schlesinger
    Naomi Schlesinger is at the Department of Medicine, PO Box 19, Robert Wood Johnson University Hospital, New Brunswick, New Jersey 08903 0019, USA
    Nat Rev Drug Discov 10:17-8. 2011
    ....
  15. pmc Canakinumab relieves symptoms of acute flares and improves health-related quality of life in patients with difficult-to-treat Gouty Arthritis by suppressing inflammation: results of a randomized, dose-ranging study
    Naomi Schlesinger
    Division of Rheumatology, Department of Medicine, Robert Wood Johnson Medical School, 125 Patterson Street, New Brunswick, NJ 089010, USA
    Arthritis Res Ther 13:R53. 2011
    ..We report the impact of canakinumab, a fully human anti-interleukin-1β monoclonal antibody, on inflammation and health-related quality of life (HRQoL) in patients with difficult-to-treat Gouty Arthritis...
  16. pmc Canakinumab reduces the risk of acute gouty arthritis flares during initiation of allopurinol treatment: results of a double-blind, randomised study
    Naomi Schlesinger
    Division of Rheumatology, Department of Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, USA
    Ann Rheum Dis 70:1264-71. 2011
    ..This study assessed the efficacy and safety of canakinumab, a fully human anti-interleukin 1β monoclonal antibody, for prophylaxis against acute gouty arthritis flares in patients initiating urate-lowering treatment...
  17. pmc Can ultrasonography make identification of asymptomatic hyperuricemic individuals at risk for developing gouty arthritis more crystal clear?
    Naomi Schlesinger
    Arthritis Res Ther 13:107. 2011
    ..Ultrasonography may serve as a noninvasive means to diagnose gouty arthritis in hyperuricemic individuals who have yet to develop symptomatic gouty arthritis...
  18. doi request reprint Difficult-to-treat gouty arthritis: a disease warranting better management
    Naomi Schlesinger
    Division of Rheumatology, Department of Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, NJ, USA
    Drugs 71:1413-39. 2011
    ....
  19. ncbi request reprint Reassessing the safety of intravenous and compounded injectable colchicine in acute gout treatment
    Naomi Schlesinger
    Division of Rheumatology, UMDNJ Robert Wood Johnson Medical School, New Brunswick, NJ 08901 1977, USA
    Expert Opin Drug Saf 6:625-9. 2007
    ..v. colchicine the treatment of acute gout...
  20. ncbi request reprint Gout: can management be improved?
    N Schlesinger
    Section of Rheumatology, UMDNJ New Jersey Medical School, Newark, New Jersey 07103 2714, USA
    Curr Opin Rheumatol 13:240-4. 2001
    ..Treatment of gout in transplant recipients brings into focus some of the issues regarding management of gout, because gout is a common problem among transplant patients...
  21. ncbi request reprint Clues to pathogenesis of fibromyalgia in patients with sickle cell disease
    Naomi Schlesinger
    Department of Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903 0019, USA
    J Rheumatol 31:598-600. 2004
    ..To investigate the association between sickle cell disease (SCD) and fibromyalgia (FM)...
  22. ncbi request reprint Management of acute and chronic gouty arthritis: present state-of-the-art
    Naomi Schlesinger
    Department of Medicine, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903 0019, USA
    Drugs 64:2399-416. 2004
    ..The effectiveness of colchicine prophylaxis as an isolated therapy is still to be confirmed by placebo-controlled trials. Another issue is prophylaxis with NSAIDs. There are no comparative studies with colchicine...
  23. ncbi request reprint Seasonal variation of lupus nephritis: high prevalence of class V lupus nephritis during the winter and spring
    Naomi Schlesinger
    Department of Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903 0019, USA
    J Rheumatol 32:1053-7. 2005
    ..Systemic lupus erythematosus is a multisystem disease with many clinical variations, including renal involvement. Our aim was to determine whether lupus nephritis (LN) has a specific seasonality...
  24. ncbi request reprint Tuberculosis of the spine: experience in an inner city hospital
    Naomi Schlesinger
    Department of Medicine, Rheumatology Division, University of Medicine and Dentistry of New Jersey Robert Wood Johnson University Hospital, 1 Robert Wood Johnson Place, PO Box 19, New Brunswick, NJ 08903 0019, USA
    J Clin Rheumatol 11:17-20. 2005
    ..It is estimated that 10 to 15 million people are infected with Mycobacterium tuberculosis in the United States. Spinal involvement is said to occur in less than 1%...
  25. ncbi request reprint Response to application of ice may help differentiate between gouty arthritis and other inflammatory arthritides
    Naomi Schlesinger
    Clinical Rheumatology, Department of Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903 0019, USA
    J Clin Rheumatol 12:275-6. 2006
    ..The aim is to determine whether response to topical ice versus heat differentiates between patients with gout versus other arthritides...
  26. ncbi request reprint Dietary factors and hyperuricaemia
    Naomi Schlesinger
    Department of Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, NJ 08903 0019, USA
    Curr Pharm Des 11:4133-8. 2005
    ..In addition, fruits, such as cherries and high intakes of vegetable protein diet may reduce serum urate levels...
  27. ncbi request reprint Treatment of acute gout in hospitalized patients
    Danielle Petersel
    Rheumatology Division, Department of Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903 0019, USA
    J Rheumatol 34:1566-8. 2007
    ..To record practice patterns of treatment of acute gout in hospitalized patients...
  28. doi request reprint Ultrasonography shows disappearance of monosodium urate crystal deposition on hyaline cartilage after sustained normouricemia is achieved
    Ralf G Thiele
    Rheumatology Division, Department of Medicine, Cooper University Hospital, Camden, NJ, USA
    Rheumatol Int 30:495-503. 2010
    ..Sonographic changes of gout correlate with SU levels and may be a non-invasive means to track changes in the uric acid pool. Larger prospective studies are needed to further assess these potentially important findings...
  29. doi request reprint Gastrointestinal involvement in polyarteritis nodosa
    Ellen C Ebert
    Department of Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey 08901, USA
    Clin Gastroenterol Hepatol 6:960-6. 2008
    ..For PAN related to HBV, a 2-week course of corticosteroids is begun, with plasma exchanges and an antiviral agent. Corticosteroids and cyclophosphamide have improved patient outcome so that the 1-year survival rate is now about 85%...
  30. ncbi request reprint Diagnosis of gout by ultrasound
    R G Thiele
    Rheumatology Division, Department of Medicine Cooper University Hospital, Camden, NJ, USA
    Rheumatology (Oxford) 46:1116-21. 2007
    ..To establish the usefulness of ultrasonography (US) for diagnosing gout and to determine whether there are sonographic features that are characteristic for gout but not for other arthropathies...
  31. ncbi request reprint Local ice therapy during bouts of acute gouty arthritis
    Naomi Schlesinger
    Department of Medicine and New Jersey Medical School University of Medicine and Dentistry of New Jersey, Newark, USA
    J Rheumatol 29:331-4. 2002
    ..To evaluate the effect of local application of ice on duration and severity of acute gouty arthritis...
  32. ncbi request reprint Outcome evaluations in gout
    H Ralph Schumacher
    Division of Rheumatology, University of Pennsylvania School of Medicine, and Veterans Affairs Medical Center, Philadelphia, Pennsylvania 19104, USA
    J Rheumatol 34:1381-5. 2007
    ..Final validation of these outcomes has not yet been achieved. In summary, the unique problems of evaluating outcomes in gout are finally being addressed. While no measures are available for use yet, an agenda has been developed...
  33. ncbi request reprint Mycobacterium marinum arthritis mimicking rheumatoid arthritis
    Alex Lam
    Rheumatology Division, Department of Medicine, the University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903 0019, USA
    J Rheumatol 33:817-9. 2006
    ....
  34. ncbi request reprint Update on gout
    Naomi Schlesinger
    University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, NJ, USA
    Arthritis Rheum 47:563-5. 2002
  35. ncbi request reprint Diagnosis of gout: clinical, laboratory, and radiologic findings
    Naomi Schlesinger
    Am J Manag Care 11:S443-50; quiz S465-8. 2005
    ..This article presents an overview of the various classification criteria, clinical presentations, and laboratory and radiologic studies needed to make the diagnosis of gout...
  36. ncbi request reprint Purine-rich foods and the risk of gout in men
    Naomi Schlesinger
    N Engl J Med 350:2520-1; author reply 2520-1. 2004
  37. ncbi request reprint Outcome measures for acute and chronic gout
    H Ralph Schumacher
    University of Florida, Gainesville, Florida, USA
    J Rheumatol 32:2452-5. 2005
    ..Five domains for acute gout outcomes and 9 for chronic gout were identified along with proposed instruments for testing and validation. The unique problems of gout evaluation can and will be addressed...
  38. ncbi request reprint Re: Gout and risk of Parkinson disease: a prospective study
    Ilana Schlesinger
    Neurology 71:70; author reply 70. 2008
  39. ncbi request reprint Acute gouty arthritis is seasonal: possible clues to understanding the pathogenesis of gouty arthritis
    Naomi Schlesinger
    J Clin Rheumatol 11:240-2. 2005