Tatsuya Sato

Summary

Affiliation: New York University
Country: USA

Publications

  1. ncbi How does Fgf signaling from the isthmic organizer induce midbrain and cerebellum development?
    Tatsuya Sato
    Howard Hughes Medical Institute and Developmental Genetics Program, Skirball Institute of Biomolecular Medicine, Department of Cell Biology, New York University School of Medicine, New York, NY 10016, USA
    Dev Growth Differ 46:487-94. 2004
  2. ncbi The duration of Fgf8 isthmic organizer expression is key to patterning different tectal-isthmo-cerebellum structures
    Tatsuya Sato
    Developmental Biology Program, Sloan Kettering Institute, 1275 York Avenue, Box 511, New York, NY 10021, USA
    Development 136:3617-26. 2009
  3. ncbi Regulation of isthmic Fgf8 signal by sprouty2
    Asuka Suzuki-Hirano
    Department of Molecular Neurobiology, Institute of Development, Aging and Cancer, Tohoku University, Seiryo machi 4 1, Aobaku, Sendai 980 8575, Japan
    Development 132:257-65. 2005
  4. ncbi Isthmus organizer for mesencephalon and metencephalon
    Harukazu Nakamura
    Department of Molecular Neurobiology, Graduate School of Life Sciences, and Institute of Development, Aging and Cancer, Tohoku University, Seiryo machi 4 1, Aoba ku, Sendai 980 8575, Japan
    Dev Growth Differ 50:S113-8. 2008
  5. ncbi The Fgf8 signal causes cerebellar differentiation by activating the Ras-ERK signaling pathway
    Tatsuya Sato
    Department of Molecular Neurobiology, Graduate School of Life Sciences, Tohoku University, Seiryo machi 4 1, Aoba ku, Sendai 980 8575, Japan
    Development 131:4275-85. 2004
  6. ncbi Isthmus organizer for midbrain and hindbrain development
    Harukazu Nakamura
    Department of Molecular Neurobiology, Graduate School of Life Sciences and Institute of Development, Aging and Cancer, Tohoku University, Seiryo machi 4 1, Aoba ku, Sendai 980 8575, Japan
    Brain Res Brain Res Rev 49:120-6. 2005

Collaborators

Detail Information

Publications6

  1. ncbi How does Fgf signaling from the isthmic organizer induce midbrain and cerebellum development?
    Tatsuya Sato
    Howard Hughes Medical Institute and Developmental Genetics Program, Skirball Institute of Biomolecular Medicine, Department of Cell Biology, New York University School of Medicine, New York, NY 10016, USA
    Dev Growth Differ 46:487-94. 2004
    ..A lower level of signaling transduced by Fgf8a, Fgf17 and Fgf18 induce midbrain development. Numerous feedback loops then maintain appropriate mesencephalon/rhombomere1 and organizer gene expression...
  2. ncbi The duration of Fgf8 isthmic organizer expression is key to patterning different tectal-isthmo-cerebellum structures
    Tatsuya Sato
    Developmental Biology Program, Sloan Kettering Institute, 1275 York Avenue, Box 511, New York, NY 10021, USA
    Development 136:3617-26. 2009
    ..Thus, the duration as well as the strength of Fgf8 signaling is key to patterning of the mid/hindbrain region. By extrapolation, the length of Fgf8 expression could be crucial to Fgf8 function in other embryonic organizers...
  3. ncbi Regulation of isthmic Fgf8 signal by sprouty2
    Asuka Suzuki-Hirano
    Department of Molecular Neurobiology, Institute of Development, Aging and Cancer, Tohoku University, Seiryo machi 4 1, Aobaku, Sendai 980 8575, Japan
    Development 132:257-65. 2005
    ..Sprouty2 may regulate the Fgf8-Ras-ERK signaling pathway for the proper regionalization of the metencephalon and mesencephalon...
  4. ncbi Isthmus organizer for mesencephalon and metencephalon
    Harukazu Nakamura
    Department of Molecular Neurobiology, Graduate School of Life Sciences, and Institute of Development, Aging and Cancer, Tohoku University, Seiryo machi 4 1, Aoba ku, Sendai 980 8575, Japan
    Dev Growth Differ 50:S113-8. 2008
    ..In this review, the historical background of the means of identifying the isthmus organizer and the molecular mechanisms of signal transduction for tectum and cerebellum differentiation is reviewed...
  5. ncbi The Fgf8 signal causes cerebellar differentiation by activating the Ras-ERK signaling pathway
    Tatsuya Sato
    Department of Molecular Neurobiology, Graduate School of Life Sciences, Tohoku University, Seiryo machi 4 1, Aoba ku, Sendai 980 8575, Japan
    Development 131:4275-85. 2004
    ..Our results indicate that the presumptive metencephalon receives a strong Fgf8 signal that activates the Ras-ERK pathway and differentiates into the cerebellum...
  6. ncbi Isthmus organizer for midbrain and hindbrain development
    Harukazu Nakamura
    Department of Molecular Neurobiology, Graduate School of Life Sciences and Institute of Development, Aging and Cancer, Tohoku University, Seiryo machi 4 1, Aoba ku, Sendai 980 8575, Japan
    Brain Res Brain Res Rev 49:120-6. 2005
    ..A strong Fgf8 signal activates the Ras-ERK signaling pathway, which in turn activates Irx2 in a rostrodorsal part of the hindbrain, and forces this tissue to differentiate into cerebellum...