M J Ruiz-Echevarria

Summary

Affiliation: New Jersey
Country: USA

Publications

  1. ncbi request reprint The RNA binding protein Pub1 modulates the stability of transcripts containing upstream open reading frames
    M J Ruiz-Echevarria
    Department of Molecular Genetics and Microbiology, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway 08854, USA
    Cell 101:741-51. 2000
  2. pmc The surveillance complex interacts with the translation release factors to enhance termination and degrade aberrant mRNAs
    K Czaplinski
    Department of Molecular Genetics and Microbiology, Robert Wood Johnson Medical School UMDNJ, USA
    Genes Dev 12:1665-77. 1998
  3. ncbi request reprint The yeast hnRNP-like protein Hrp1/Nab4 marks a transcript for nonsense-mediated mRNA decay
    C I Gonzalez
    Department of Molecular Genetics and Microbiology, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway 08854, USA
    Mol Cell 5:489-99. 2000
  4. pmc Identifying the right stop: determining how the surveillance complex recognizes and degrades an aberrant mRNA
    M J Ruiz-Echevarria
    Department of Molecular Genetics and Microbiology, Robert Wood Johnson Medical School UMDNJ, Piscataway, NJ 08854, USA
    EMBO J 17:575-89. 1998
  5. pmc Peptidyl-transferase inhibitors have antiviral properties by altering programmed -1 ribosomal frameshifting efficiencies: development of model systems
    J D Dinman
    Department of Molecular Genetics and Microbiology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, 675 Hoes Lane, Piscataway, NJ 08854, USA
    Proc Natl Acad Sci U S A 94:6606-11. 1997

Collaborators

  • J D Dinman
  • C I Gonzalez
  • S W Peltz
  • K Czaplinski
  • S Vasudevan
  • M F Henry
  • Y Weng
  • S V Paushkin
  • M D Ter-Avanesyan
  • X Han
  • H A Perlick
  • H C Dietz

Detail Information

Publications5

  1. ncbi request reprint The RNA binding protein Pub1 modulates the stability of transcripts containing upstream open reading frames
    M J Ruiz-Echevarria
    Department of Molecular Genetics and Microbiology, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway 08854, USA
    Cell 101:741-51. 2000
    ..These results indicate that uORFs can play a pivotal role regulating both translation and turnover and that the Pub1p is a critical factor that modulates the stability of uORF-containing transcripts...
  2. pmc The surveillance complex interacts with the translation release factors to enhance termination and degrade aberrant mRNAs
    K Czaplinski
    Department of Molecular Genetics and Microbiology, Robert Wood Johnson Medical School UMDNJ, USA
    Genes Dev 12:1665-77. 1998
    ....
  3. ncbi request reprint The yeast hnRNP-like protein Hrp1/Nab4 marks a transcript for nonsense-mediated mRNA decay
    C I Gonzalez
    Department of Molecular Genetics and Microbiology, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway 08854, USA
    Mol Cell 5:489-99. 2000
    ..A mutation in HRP1 that stabilizes nonsense-containing mRNAs abolishes its affinity for the DSE and fails to interact with Upf1p. We present a model describing how Hrp1p marks a transcript for rapid decay...
  4. pmc Identifying the right stop: determining how the surveillance complex recognizes and degrades an aberrant mRNA
    M J Ruiz-Echevarria
    Department of Molecular Genetics and Microbiology, Robert Wood Johnson Medical School UMDNJ, Piscataway, NJ 08854, USA
    EMBO J 17:575-89. 1998
    ..Further, the results indicate that the STE functions in the context of the GCN4 transcript to inactivate the NMD pathway...
  5. pmc Peptidyl-transferase inhibitors have antiviral properties by altering programmed -1 ribosomal frameshifting efficiencies: development of model systems
    J D Dinman
    Department of Molecular Genetics and Microbiology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, 675 Hoes Lane, Piscataway, NJ 08854, USA
    Proc Natl Acad Sci U S A 94:6606-11. 1997
    ..Our results offer a new set of antiviral agents that may potentially have a broad range of applications in the clinical, veterinary, and agricultural fields...