B Rudy

Summary

Affiliation: New York University
Country: USA

Publications

  1. pmc DPP6 Localization in Brain Supports Function as a Kv4 Channel Associated Protein
    Brian D Clark
    Smilow Neuroscience Program, Department of Physiology and Neuroscience New York, USA
    Front Mol Neurosci 1:8. 2008
  2. pmc Dipeptidyl-peptidase-like-proteins confer high sensitivity to the scorpion toxin AmmTX3 to Kv4-mediated A-type K+ channels
    JON K MAFFIE
    Smilow Neuroscience Program, NYU School of Medicine, 522 First Avenue, New York, NY 10016, USA
    J Physiol 591:2419-27. 2013
  3. ncbi request reprint Kv3 channels: voltage-gated K+ channels designed for high-frequency repetitive firing
    B Rudy
    Dept of Physiology and Neuroscience, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    Trends Neurosci 24:517-26. 2001
  4. ncbi request reprint Molecular diversity of K+ channels
    W A Coetzee
    Department of Physiology, New York University School of Medicine, New York 10016, USA
    Ann N Y Acad Sci 868:233-85. 1999
  5. pmc A role for frequenin, a Ca2+-binding protein, as a regulator of Kv4 K+-currents
    T Y Nakamura
    Department of Pediatric Cardiology, New York University School of Medicine, New York, NY 10016, USA
    Proc Natl Acad Sci U S A 98:12808-13. 2001
  6. pmc Modulation of Kv3 potassium channels expressed in CHO cells by a nitric oxide-activated phosphatase
    H Moreno
    Department of Physiology and Neuroscience, New York University School of Medicine, NY 10016, USA
    J Physiol 530:345-58. 2001
  7. ncbi request reprint KT3.2 and KT3.3, two novel human two-pore K(+) channels closely related to TASK-1
    E Vega-Saenz de Miera
    Department of Physiology and Neuroscience, New York University School of Medicine, New York, New York 10016, USA
    J Neurophysiol 86:130-42. 2001
  8. ncbi request reprint Cloning of components of a novel subthreshold-activating K(+) channel with a unique pattern of expression in the cerebral cortex
    M J Saganich
    Department of Physiology, New York University School of Medicine, New York, New York, 10016, USA
    J Neurosci 19:10789-802. 1999
  9. pmc Evidence for the presence of a novel Kv4-mediated A-type K(+) channel-modifying factor
    M S Nadal
    Department of Physiology and Neuroscience, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    J Physiol 537:801-9. 2001
  10. ncbi request reprint Different effects of the Ca(2+)-binding protein, KChIP1, on two Kv4 subfamily members, Kv4.1 and Kv4.2
    T Y Nakamura
    Pediatric Cardiology, NYU School of Medicine, NY 10016, USA
    FEBS Lett 499:205-9. 2001

Collaborators

  • Jennifer Lanning
  • S Nandi
  • D Contreras
  • S Ueda
  • C J McBain
  • M E Martone
  • D J Pountney
  • A Hernandez-Cruz
  • E Vega-Saenz de Miera
  • A Ozaita
  • W A Coetzee
  • M S Nadal
  • H Moreno
  • JON K MAFFIE
  • A Chow
  • T Y Nakamura
  • M J Saganich
  • Y Amarillo
  • D Lau
  • Brian D Clark
  • E C Vega-Saenz de Miera
  • T McCormack
  • Marie France Martin-Eauclaire
  • Pierre Edouard Bougis
  • Elena Dvoretskova
  • Jon Maffie
  • R Hernandez-Pineda
  • M Saganich
  • Marcela Nadal
  • Pavel Strop
  • Elaine Kwon
  • Hyo Young Jeong
  • A Ponce
  • M H Ellisman
  • E Machado
  • M Artman
  • M Zhadina
  • D H Lau
  • J L Noebels
  • C S Leonard
  • M Harvey
  • R Paylor
  • J I Morgan
  • C Farb
  • J Chiu
  • M F Seldin
  • H Baker
  • A Erisir
  • E Welker
  • B Thornhill
  • M Sugimori
  • R Llinas
  • C Kentros

Detail Information

Publications20

  1. pmc DPP6 Localization in Brain Supports Function as a Kv4 Channel Associated Protein
    Brian D Clark
    Smilow Neuroscience Program, Department of Physiology and Neuroscience New York, USA
    Front Mol Neurosci 1:8. 2008
    ..However, we also found that DPP6 antibodies intensely labeled the hippocampal mossy fiber axons, which lack Kv4 proteins, suggesting that DPP6 proteins may have additional, Kv4-unrelated functions...
  2. pmc Dipeptidyl-peptidase-like-proteins confer high sensitivity to the scorpion toxin AmmTX3 to Kv4-mediated A-type K+ channels
    JON K MAFFIE
    Smilow Neuroscience Program, NYU School of Medicine, 522 First Avenue, New York, NY 10016, USA
    J Physiol 591:2419-27. 2013
    ..These studies validate the use of AmmTX3 as a blocker of the Kv4-mediated A-type K+ current in neurons...
  3. ncbi request reprint Kv3 channels: voltage-gated K+ channels designed for high-frequency repetitive firing
    B Rudy
    Dept of Physiology and Neuroscience, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    Trends Neurosci 24:517-26. 2001
    ....
  4. ncbi request reprint Molecular diversity of K+ channels
    W A Coetzee
    Department of Physiology, New York University School of Medicine, New York 10016, USA
    Ann N Y Acad Sci 868:233-85. 1999
    ....
  5. pmc A role for frequenin, a Ca2+-binding protein, as a regulator of Kv4 K+-currents
    T Y Nakamura
    Department of Pediatric Cardiology, New York University School of Medicine, New York, NY 10016, USA
    Proc Natl Acad Sci U S A 98:12808-13. 2001
    ..Together, our data provide strong support for the concept that frequenin may be an important Ca(2+)-sensitive regulatory component of native A-type K(+) currents...
  6. pmc Modulation of Kv3 potassium channels expressed in CHO cells by a nitric oxide-activated phosphatase
    H Moreno
    Department of Physiology and Neuroscience, New York University School of Medicine, NY 10016, USA
    J Physiol 530:345-58. 2001
    ..Activation of phosphatases via NO or other signals that increase cGMP might be a potent mechanism to regulate Kv3 channel activity in neurons...
  7. ncbi request reprint KT3.2 and KT3.3, two novel human two-pore K(+) channels closely related to TASK-1
    E Vega-Saenz de Miera
    Department of Physiology and Neuroscience, New York University School of Medicine, New York, New York 10016, USA
    J Neurophysiol 86:130-42. 2001
    ..Medium expression levels were found in neocortex. The KT3.2 gene is located at chromosome 8q24 1-3, and the KT3.3 gene maps to chromosome 20q13.1...
  8. ncbi request reprint Cloning of components of a novel subthreshold-activating K(+) channel with a unique pattern of expression in the cerebral cortex
    M J Saganich
    Department of Physiology, New York University School of Medicine, New York, New York, 10016, USA
    J Neurosci 19:10789-802. 1999
    ..Given their functional properties and specific distribution, Eag2 channels may play roles in the regulation of the behavioral state-dependent entry of sensory information to the cerebral cortex...
  9. pmc Evidence for the presence of a novel Kv4-mediated A-type K(+) channel-modifying factor
    M S Nadal
    Department of Physiology and Neuroscience, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    J Physiol 537:801-9. 2001
    ..4. The time course of the currents expressed by KAF-modified Kv4 channels resembles more closely the time course of the native I(SA) in cerebellar granule cells...
  10. ncbi request reprint Different effects of the Ca(2+)-binding protein, KChIP1, on two Kv4 subfamily members, Kv4.1 and Kv4.2
    T Y Nakamura
    Pediatric Cardiology, NYU School of Medicine, NY 10016, USA
    FEBS Lett 499:205-9. 2001
    ..2 and Kv4.1. These results reveal a novel interaction of KChIP1 with these two Kv4 members. This represents a mechanism to further increase the functional diversity of K(+) channels...
  11. ncbi request reprint Kv3.1-Kv3.2 channels underlie a high-voltage-activating component of the delayed rectifier K+ current in projecting neurons from the globus pallidus
    R Hernandez-Pineda
    Department of Physiology and Neuroscience and Department of Biochemistry, New York University School of Medicine, New York City, New York 10016, USA
    J Neurophysiol 82:1512-28. 1999
    ..Kv3.1-Kv3.2 voltage-gated K+ channels may play a role in helping maintain sustained high-frequency repetitive firing as they probably do in other neurons...
  12. ncbi request reprint K(+) channel expression distinguishes subpopulations of parvalbumin- and somatostatin-containing neocortical interneurons
    A Chow
    Departments of Physiology and Neuroscience and Biochemistry, New York University School of Medicine, New York, New York, 10016, USA
    J Neurosci 19:9332-45. 1999
    ..1 proteins are also prominent in a subset of seemingly non-fast-spiking, somatostatin- and calbindin-containing interneurons, suggesting that the Kv3.1-Kv3.2 current type can have functions other than facilitating high-frequency firing...
  13. ncbi request reprint Differential subcellular localization of the two alternatively spliced isoforms of the Kv3.1 potassium channel subunit in brain
    A Ozaita
    Department of Physiology and Neuroscience and Department of Biochemistry, New York University School of Medicine, New York, New York 10016, USA
    J Neurophysiol 88:394-408. 2002
    ..1a protein in dendritic and somatic membrane, respectively. The results support the hypothesis that the alternative spliced C-termini of Kv3 subunits regulate their subcellular targeting in neurons...
  14. ncbi request reprint Impaired fast-spiking, suppressed cortical inhibition, and increased susceptibility to seizures in mice lacking Kv3.2 K+ channel proteins
    D Lau
    Departments of Physiology and Neuroscience, and Biochemistry, New York University School of Medicine, New York, New York 10016, USA
    J Neurosci 20:9071-85. 2000
    ..2 channel elimination suppresses their activity. These data suggest that normal cortical operations depend on the ability of inhibitory interneurons to generate high-frequency firing...
  15. ncbi request reprint Differential expression of genes encoding subthreshold-operating voltage-gated K+ channels in brain
    M J Saganich
    Department of Physiology and Neuroscience and Department of Biochemistry, New York University School of Medicine, New York, New York 10016
    J Neurosci 21:4609-24. 2001
    ..This indicates that the subthreshold current in many neurons may be complex, containing different components mediated by a number of channels with distinct properties and neuromodulatory responses...
  16. ncbi request reprint Contributions of Kv3 channels to neuronal excitability
    B Rudy
    Department of Physiology and Neuroscience, New York University of Medicine, New York 10016, USA
    Ann N Y Acad Sci 868:304-43. 1999
    ..Experimental evidence has now become available showing that Kv3.1-Kv3.2 channels play critical roles in the generation of fast-spiking properties in cortical GABAergic interneurons...
  17. ncbi request reprint K+ channel subunit isoforms with divergent carboxy-terminal sequences carry distinct membrane targeting signals
    A Ponce
    Department of Physiology and Neuroscience, New York University Medical Center, 550 First Avenue, New York, NY 10016, USA
    J Membr Biol 159:149-59. 1997
    ....
  18. pmc Molecular characterization of the sodium channel subunits expressed in mammalian cerebellar Purkinje cells
    E C Vega-Saenz de Miera
    Department of Physiology and Neuroscience, New York University Medical Center, 550 First Avenue, New York, NY 10016, USA
    Proc Natl Acad Sci U S A 94:7059-64. 1997
    ..Conversely, jolting mice with a mutated Scn8a message demonstrates PC abnormalities in rapid, simple spike generation, linking CerIII to the persistent sodium current...
  19. ncbi request reprint Identification and cloning of TWIK-originated similarity sequence (TOSS): a novel human 2-pore K+ channel principal subunit
    D J Pountney
    Department of Pediatric Cardiology, New York University School of Medicine, NY 10016, USA
    FEBS Lett 450:191-6. 1999
    ....
  20. ncbi request reprint Chromosomal mapping of the potassium channel genes Kcnq2 and Kcnq3 in mouse
    T McCormack
    Department of Physiology, New York University Medical Center, New York, New York 10016, USA
    Genomics 56:360-1. 1999