Research Topics
| P RiggsSummaryAffiliation: New England Biolabs Country: USA Publications
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Detail Information
Publications
Mutations in maltose-binding protein that alter affinity and solubility propertiesIris H Walker
New England Biolabs, 240 County Rd, Ipswich, MA 01938 2723, USA
Appl Microbiol Biotechnol 88:187-97. 2010..Some of the mutations we obtained can be rationalized based on the previous work, while others indicate new ways in which the function of MBP can be modified...
Expression and purification of recombinant proteins by fusion to maltose-binding proteinP Riggs
New England Biolabs, Beverly, MA, USA
Mol Biotechnol 15:51-63. 2000..Vectors with or without the malE signal sequence can be used, to express the protein cytoplasmically for the highest level of production or periplasmically to help in proper folding of disulfide-bonded proteins...
Expression and purification of maltose-binding protein fusionsP Riggs
New England Biolabs, Beverly, Massachusetts, USA
Curr Protoc Mol Biol . 2001..Additional support protocols detail two different chromatographic methods for separating the protein of interest from MBP after factor Xa cleavage...
Introduction to expression by fusion protein vectorsP Riggs
New England Biolabs, Beverly, Massachusetts, USA
Curr Protoc Mol Biol . 2001..g., heat stability) can be exploited to allow selective purification of the fusion protein. Often, proteins fused to these carriers can be separated from the bulk of intracellular contaminants by taking advantage of special attributes...
