Affiliation: New York University School of Medicine
- Synaptic autoregulation by metalloproteases and γ-secretaseSophie Restituito
Department of Biochemistry, New York University Langone Medical Center, New York, New York 10016, USA
J Neurosci 31:12083-93. 2011..Our results suggest that activity-dependent substrate cleavage by synaptic metalloproteases and γ-secretase modifies synaptic transmission, providing a novel form of synaptic autoregulation...
- Regulation of synaptic structure and function by palmitoylated AMPA receptor binding proteinCharu Misra
Department of Biochemistry, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
Mol Cell Neurosci 43:341-52. 2010..Thus postsynaptic pABP-L induces pre and postsynaptic changes that are dependent on palmitoylation and likely achieved through ABP association with a multi-molecular cell surface signaling complex...
- Synaptic anchorage of AMPA receptors by cadherins through neural plakophilin-related arm protein AMPA receptor-binding protein complexesJoshua B Silverman
Department of Biochemistry, New York University School of Medicine, New York, New York 10016, USA
J Neurosci 27:8505-16. 2007..Thus, the interaction of scaffolding proteins with cadherin-NPRAP complexes may anchor diverse signaling and adhesion molecules at cadherins...
- A role for huntington disease protein in dendritic RNA granulesJeffrey N Savas
Department of Microbiology, New York University School of Medicine, New York, New York 10016, USA
J Biol Chem 285:13142-53. 2010..When tethered to a reporter construct, Htt down-regulated reporter gene expression in a manner dependent on Ago2, suggesting that Htt may function to repress translation of mRNAs during transport in neuronal granules...