Research Topics
| Elizabeth A RaetzSummaryAffiliation: New York University School of Medicine Country: USA Publications
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Detail Information
Publications
Where do we stand in the treatment of relapsed acute lymphoblastic leukemia?Elizabeth A Raetz
Division of Pediatric Hematology Oncology, New York University Langone Medical Center, New York, NY, USA
Hematology Am Soc Hematol Educ Program 2012:129-36. 2012..Recently, high-resolution genomic analyses of matched pairs of diagnostic and relapse bone marrow samples are emerging as a promising tool for identifying pathways that impart chemoresistance...
Tolerability and efficacy of L-asparaginase therapy in pediatric patients with acute lymphoblastic leukemiaElizabeth A Raetz
Division of Pediatric Hematology Oncology, Department of Pediatrics, New York University School of Medicine, New York, NY 10016, USA
J Pediatr Hematol Oncol 32:554-63. 2010..The spectrum of common toxicities and the efficacy of different formulations of L-ASNase are presented in this review...
Reinduction platform for children with first marrow relapse of acute lymphoblastic Leukemia: A Children's Oncology Group Study[corrected]Elizabeth A Raetz
New York University School of Medicine, Hassenfeld Children s Center for Cancer and Blood Disorders, 160 E 32nd St, New York, NY 10016, USA
J Clin Oncol 26:3971-8. 2008..The goal of the Children's Oncology Group (COG) AALL01P2 study was to develop a safe and active chemotherapy reinduction platform, which could be used to evaluate novel agents in future trials...
Chemoimmunotherapy reinduction with epratuzumab in children with acute lymphoblastic leukemia in marrow relapse: a Children's Oncology Group Pilot StudyElizabeth A Raetz
Department of Pediatrics, New York University, School of Medicine, Hassenfeld Children s Center for Cancer and Blood Disorders, New York, NY 10016, USA
J Clin Oncol 26:3756-62. 2008....
Biologic pathways associated with relapse in childhood acute lymphoblastic leukemia: a Children's Oncology Group studyDeepa Bhojwani
New York University (NYU) Cancer Institute and Division of Pediatric Hematology/Oncology, NY 10016, USA
Blood 108:711-7. 2006..These results suggest that early-relapse results from the emergence of a related clone, characterized by the up-regulation of genes mediating cell proliferation. In contrast, late relapse appears to be mediated by diverse pathways...
Potential of gene expression profiling in the management of childhood acute lymphoblastic leukemiaDeepa Bhojwani
NYU Cancer Institute, Division of Pediatric Hematology, New York University School of Medicine, New York, New York 10016, USA
Paediatr Drugs 9:149-56. 2007..These newer methods of genome analyses complemented by studies involving the proteome as well as host polymorphisms will have a profound impact on the diagnosis and management of childhood ALL...
Childhood acute lymphoblastic leukemia in the age of genomicsWilliam L Carroll
Division of Pediatric Hematology Oncology, New York University Cancer Institute, New York University School of Medicine, New York City, New York, USA
Pediatr Blood Cancer 46:570-8. 2006..New bioinformatics tools optimize data mining, but validation of findings is essential since "over-fitting" the data is a common danger. In the future, genomic analysis will be complemented by evaluation of the cancer proteome...
Gene expression signatures predictive of early response and outcome in high-risk childhood acute lymphoblastic leukemia: A Children's Oncology Group Study [corrected]Deepa Bhojwani
Division of Pediatric Hematology Oncology, New York University Cancer Institute, New York University School of Medicine, New York, NY 10016, USA
J Clin Oncol 26:4376-84. 2008..To identify children with acute lymphoblastic leukemia (ALL) at initial diagnosis who are at risk for inferior response to therapy by using molecular signatures...
Building better therapy for children with acute lymphoblastic leukemiaWilliam L Carroll
Stephen D Hassenfeld Children s Center for Cancer and Blood Diseases, New York University Cancer Institute, New York, New York 10016, USA
Cancer Cell 7:289-91. 2005..The goal is now to integrate these and other findings using gene expression technology into the care of children with the most common pediatric malignancy...
Epigenetic reprogramming reverses the relapse-specific gene expression signature and restores chemosensitivity in childhood B-lymphoblastic leukemiaTeena Bhatla
New York University Cancer Institute, New York University Langone Medical Center, New York, NY 10016, USA
Blood 119:5201-10. 2012..Incorporation of these targeted epigenetic agents to the standard chemotherapy backbone is a promising approach to the treatment of relapsed pediatric acute lymphoblastic leukemia...
Eliminating a gold standard in childhood acute lymphoblastic leukemia?Elizabeth A Raetz
Department of Pediatrics, Division of Pediatric Hematology Oncology, NYU Cancer Institute, NYU School of Medicine, New York, New York 10016, USA
Pediatr Blood Cancer 47:242-4. 2006
Identification of genes that are regulated transcriptionally by Myc in childhood tumorsElizabeth A Raetz
Mount Sinai School of Medicine, New York, New York, USA
Cancer 98:841-53. 2003....
Well-differentiated pancreatic neuroendocrine carcinoma in tuberous sclerosis--case report and review of the literatureNicoleta C Arva
Department of Pathology, New York University Langone Medical Center, New York, NY, USA
Am J Surg Pathol 36:149-53. 2012..We present a case of well-differentiated neuroendocrine carcinoma of the pancreas in a child with TSC and discuss the genetic aspects of this disease...
"When can I go home?"-seeking ways to lower the burden on patients and familiesWilliam L Carroll
Division of Pediatric Hematology Oncology, Department of Pediatrics, NYU Cancer Institute, NYU School of Medicine, New York 10016, USA
Pediatr Blood Cancer 51:318-9. 2008
Gene expression profiling reveals intrinsic differences between T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphomaElizabeth A Raetz
Division of Pediatric Hematology Oncology, Mount Sinai School of Medicine, New York, New York, USA
Pediatr Blood Cancer 47:130-40. 2006..However, despite these similarities, differences in the clinical behavior of T-ALL and T-LL are observed...
Identification of gene expression profiles that segregate patients with childhood leukemiaPhilip J Moos
Center for Children at the Huntsman Cancer Institute and Oncological Sciences, University of Utah School of Medicine, Salt Lake City, Utah 84112, USA
Clin Cancer Res 8:3118-30. 2002....
Impact of microarray technology in clinical oncologyElizabeth A Raetz
Division of Hematology-Oncology, Huntsman Cancer Institute, University of Utah School of Medicine, Primary Children's Medical Center, Salt Lake City, Utah, USA
Cancer Invest 22:312-20. 2004..The dynamic nature of this field ensures that new developments are missing from this review...
The nucleophosmin-anaplastic lymphoma kinase fusion protein induces c-Myc expression in pediatric anaplastic large cell lymphomasElizabeth A Raetz
Center for Children at the Huntsman Cancer Institute, Salt Lake City, Utah, USA
Am J Pathol 161:875-83. 2002..C-Myc may be a downstream target of ALK signaling and its expression a defining characteristic of ALK-positive ALCLs...
