Haiyan Qi

Summary

Affiliation: New Jersey
Country: USA

Publications

  1. ncbi request reprint Inactivation of Cdc13p triggers MEC1-dependent apoptotic signals in yeast
    Haiyan Qi
    Department of Pharmacology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA
    J Biol Chem 278:15136-41. 2003
  2. ncbi request reprint G-quadruplexes induce apoptosis in tumor cells
    Haiyan Qi
    Department of Pharmacology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA
    Cancer Res 66:11808-16. 2006
  3. pmc TOR regulates cell death induced by telomere dysfunction in budding yeast
    Haiyan Qi
    Department of Pharmacology, UMDNJ Robert Wood Johnson Medical School, Piscataway, NJ, USA
    PLoS ONE 3:e3520. 2008
  4. pmc Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation
    Xuan Fu
    Department of Pharmacology, UMDNJ Robert Wood Johnson Medical School, Piscataway, New Jersey, United States of America
    PLoS ONE 3:e2009. 2008
  5. pmc A G-quadruplex stabilizer induces M-phase cell cycle arrest
    Yuan Chin Tsai
    Department of Pharmacology, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, Piscataway, New Jersey 08854 5635, USA
    J Biol Chem 284:22535-43. 2009
  6. ncbi request reprint Protection of DNA ends by telomeric 3' G-tail sequences
    Yuan Chin Tsai
    Department of Pharmacology, University of Medicine and Dentistry of New Jersey UMDNJ Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA
    J Biol Chem 282:18786-92. 2007
  7. ncbi request reprint Single-stranded DNA induces ataxia telangiectasia mutant (ATM)/p53-dependent DNA damage and apoptotic signals
    Alam Nur-E-Kamal
    Department of Pharmacology, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway, New Jersey 08854, USA
    J Biol Chem 278:12475-81. 2003
  8. ncbi request reprint The role of autophagy in mitochondria maintenance: characterization of mitochondrial functions in autophagy-deficient S. cerevisiae strains
    Yong Zhang
    Pharmacology Department and the Cancer Institute of New Jersey, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA
    Autophagy 3:337-46. 2007
  9. ncbi request reprint Autophagy regulates ageing in C. elegans
    Eszter S Hars
    Department of Pharmacology, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA
    Autophagy 3:93-5. 2007
  10. pmc Schizosaccharomyces pombe pfh1+ encodes an essential 5' to 3' DNA helicase that is a member of the PIF1 subfamily of DNA helicases
    Jin Qiu Zhou
    Princeton University, Department of Molecular Biology, Princeton, New Jersey 08544, USA
    Mol Biol Cell 13:2180-91. 2002

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Inactivation of Cdc13p triggers MEC1-dependent apoptotic signals in yeast
    Haiyan Qi
    Department of Pharmacology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA
    J Biol Chem 278:15136-41. 2003
    ..Our results are consistent with a model in which single-stranded G-tails in the cdc13-1 mutant trigger MEC1-dependent apoptotic signaling in yeast...
  2. ncbi request reprint G-quadruplexes induce apoptosis in tumor cells
    Haiyan Qi
    Department of Pharmacology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA
    Cancer Res 66:11808-16. 2006
    ..Interestingly, a number of G-quadruplex ODNs (GQ-ODN) derived from nontelomeric sequences also induced ATM/JNK-dependent apoptosis, suggesting a possible common mechanism of tumor cell killing by GQ-ODNs...
  3. pmc TOR regulates cell death induced by telomere dysfunction in budding yeast
    Haiyan Qi
    Department of Pharmacology, UMDNJ Robert Wood Johnson Medical School, Piscataway, NJ, USA
    PLoS ONE 3:e3520. 2008
    ..In the aggregate, our results suggest that the TOR signaling pathway is specifically involved in the regulation of cell death initiated by telomere dysfunction...
  4. pmc Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation
    Xuan Fu
    Department of Pharmacology, UMDNJ Robert Wood Johnson Medical School, Piscataway, New Jersey, United States of America
    PLoS ONE 3:e2009. 2008
    ..Here we provide evidence for a novel role of ATM in mitochondrial biogenesis through AMPK activation in response to etoposide-induced DNA damage...
  5. pmc A G-quadruplex stabilizer induces M-phase cell cycle arrest
    Yuan Chin Tsai
    Department of Pharmacology, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, Piscataway, New Jersey 08854 5635, USA
    J Biol Chem 284:22535-43. 2009
    ..In the aggregate, our results suggest that HXDV, which exhibits anti-proliferative and apoptotic activities, is also a novel M-phase blocker, with a mode of action dependent on its G-quadruplex binding activity...
  6. ncbi request reprint Protection of DNA ends by telomeric 3' G-tail sequences
    Yuan Chin Tsai
    Department of Pharmacology, University of Medicine and Dentistry of New Jersey UMDNJ Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA
    J Biol Chem 282:18786-92. 2007
    ..These results suggest that the ability of telomeric 3' G-tails to adopt the endprotecting G-quadruplex conformation may be one of the reasons for the existence of the evolutionarily conserved G-stretch motifs in telomeric DNA sequences...
  7. ncbi request reprint Single-stranded DNA induces ataxia telangiectasia mutant (ATM)/p53-dependent DNA damage and apoptotic signals
    Alam Nur-E-Kamal
    Department of Pharmacology, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway, New Jersey 08854, USA
    J Biol Chem 278:12475-81. 2003
    ..These results suggest that single-stranded DNA may act upstream of ATM/p53 in DNA damage signaling...
  8. ncbi request reprint The role of autophagy in mitochondria maintenance: characterization of mitochondrial functions in autophagy-deficient S. cerevisiae strains
    Yong Zhang
    Pharmacology Department and the Cancer Institute of New Jersey, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA
    Autophagy 3:337-46. 2007
    ..This study clearly indicates that an autophagy defect has a functional impact on various aspects of mitochondrial functions and suggests a critical role of autophagy in mitochondria maintenance...
  9. ncbi request reprint Autophagy regulates ageing in C. elegans
    Eszter S Hars
    Department of Pharmacology, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA
    Autophagy 3:93-5. 2007
    ..elegans using RNAi. We showed that RNAi shortened the lifespan of both wild type and daf-2 mutant C. elegans, providing strong support for a role of autophagy in ageing regulation...
  10. pmc Schizosaccharomyces pombe pfh1+ encodes an essential 5' to 3' DNA helicase that is a member of the PIF1 subfamily of DNA helicases
    Jin Qiu Zhou
    Princeton University, Department of Molecular Biology, Princeton, New Jersey 08544, USA
    Mol Biol Cell 13:2180-91. 2002
    ..Telomeric DNA was modestly shortened in the absence of Pfh1p. However, genetic analysis demonstrated that maintenance of telomeric DNA was not the sole essential function of S. pombe Pfh1p...