Catherine B Poole

Summary

Affiliation: New England Biolabs
Country: USA

Publications

  1. ncbi Subtilisin-like proteases in nematodes
    Catherine B Poole
    New England Biolabs, 240 County Road, Ipswich, MA 01938, USA
    Mol Biochem Parasitol 155:1-8. 2007
  2. doi Cloning and bioinformatic identification of small RNAs in the filarial nematode, Brugia malayi
    Catherine B Poole
    New England Biolabs, 240 County Rd, Ipswich, MA 01938, USA
    Mol Biochem Parasitol 169:87-94. 2010
  3. doi Protein mediated miRNA detection and siRNA enrichment using p19
    Jingmin Jin
    New England Biolabs, Ipswich, MA 01938, USA
    Biotechniques 48:xvii-xxiii. 2010
  4. pmc Diversity and expression of microRNAs in the filarial parasite, Brugia malayi
    Catherine B Poole
    Division of RNA Biology, New England Biolabs, Ipswich, Massachusetts, United States of America Division of Parasitology, New England Biolabs, Ipswich, Massachusetts, United States of America
    PLoS ONE 9:e96498. 2014
  5. doi Expanding the MDx toolbox for filarial diagnosis and surveillance
    Andy Alhassan
    Division of Genome Biology, New England Biolabs, Ipswich, MA 01938, USA
    Trends Parasitol 31:391-400. 2015
  6. ncbi Cloning and biochemical characterization of blisterase, a subtilisin-like convertase from the filarial parasite, Onchocerca volvulus
    Catherine B Poole
    Molecular Parasitology Division, New England Biolabs, Beverly, Massachusetts 01915, USA
    J Biol Chem 278:36183-90. 2003
  7. pmc A target repurposing approach identifies N-myristoyltransferase as a new candidate drug target in filarial nematodes
    Brendan D Galvin
    New England Biolabs, Division of Genome Biology, Ipswich, Massachusetts, United States of America
    PLoS Negl Trop Dis 8:e3145. 2014
  8. pmc Diagnosis of brugian filariasis by loop-mediated isothermal amplification
    Catherine B Poole
    New England Biolabs, Ipswich, Massachusetts, United States of America
    PLoS Negl Trop Dis 6:e1948. 2012

Collaborators

Detail Information

Publications8

  1. ncbi Subtilisin-like proteases in nematodes
    Catherine B Poole
    New England Biolabs, 240 County Road, Ipswich, MA 01938, USA
    Mol Biochem Parasitol 155:1-8. 2007
    ....
  2. doi Cloning and bioinformatic identification of small RNAs in the filarial nematode, Brugia malayi
    Catherine B Poole
    New England Biolabs, 240 County Rd, Ipswich, MA 01938, USA
    Mol Biochem Parasitol 169:87-94. 2010
    ..malayi uses an RNAi mechanism to maintain genome integrity. Analysis of these data provides a first glimpse into how small RNA-mediated silencing pathways regulate the parasitic life cycle of B. malayi...
  3. doi Protein mediated miRNA detection and siRNA enrichment using p19
    Jingmin Jin
    New England Biolabs, Ipswich, MA 01938, USA
    Biotechniques 48:xvii-xxiii. 2010
    ..These studies demonstrate the potential of p19 fusion protein to detect miRNAs and isolate endogenous siRNAs...
  4. pmc Diversity and expression of microRNAs in the filarial parasite, Brugia malayi
    Catherine B Poole
    Division of RNA Biology, New England Biolabs, Ipswich, Massachusetts, United States of America Division of Parasitology, New England Biolabs, Ipswich, Massachusetts, United States of America
    PLoS ONE 9:e96498. 2014
    ..Characterization of B. malayi miRNAs and their targets will enhance our understanding of their regulatory pathways in filariads and aid in the search for novel therapeutics...
  5. doi Expanding the MDx toolbox for filarial diagnosis and surveillance
    Andy Alhassan
    Division of Genome Biology, New England Biolabs, Ipswich, MA 01938, USA
    Trends Parasitol 31:391-400. 2015
    ..We briefly describe recent developments in isothermal nucleic acid amplification and detection, and focus on emerging technologies that are field-deployable or suitable for low-resource settings. ..
  6. ncbi Cloning and biochemical characterization of blisterase, a subtilisin-like convertase from the filarial parasite, Onchocerca volvulus
    Catherine B Poole
    Molecular Parasitology Division, New England Biolabs, Beverly, Massachusetts 01915, USA
    J Biol Chem 278:36183-90. 2003
    ..This report describes the first biochemical characterization of the nematode specific protease, blisterase...
  7. pmc A target repurposing approach identifies N-myristoyltransferase as a new candidate drug target in filarial nematodes
    Brendan D Galvin
    New England Biolabs, Division of Genome Biology, Ipswich, Massachusetts, United States of America
    PLoS Negl Trop Dis 8:e3145. 2014
    ..These results suggest that targeting NMT could be a valid approach for the development of chemotherapeutic agents against nematode diseases including filariasis. ..
  8. pmc Diagnosis of brugian filariasis by loop-mediated isothermal amplification
    Catherine B Poole
    New England Biolabs, Ipswich, Massachusetts, United States of America
    PLoS Negl Trop Dis 6:e1948. 2012
    ..The results indicate that the Brugia Hha I repeat LAMP assay is rapid, sensitive and Brugia-specific with the potential to be developed further as a field tool for diagnosis and mapping of brugian filariasis...