Research Topics
Species | COLIN K PHOONSummaryAffiliation: New York University Country: USA Publications
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Publications
Finding the "PR-fect" solution: what is the best tool to measure fetal cardiac PR intervals for the detection and possible treatment of early conduction disease?Colin K L Phoon
Division of Pediatric Cardiology, Department of Pediatrics, New York University School of Medicine, New York, NY, USA
Congenit Heart Dis 7:349-60. 2012..Of concern, despite anecdotal evidence, there is currently no conclusive proof that a prolonged PR interval predicts complete heart block...
Imaging tools for the developmental biologist: ultrasound biomicroscopy of mouse embryonic developmentColin Kit Lun Phoon
Pediatric Cardiology Program, New York University School of Medicine, New York 10016, USA
Pediatr Res 60:14-21. 2006..Broad, long-term research objectives are to define living structure-function relationships during critical periods of mammalian morphogenesis...
Finding balanceColin K L Phoon
Pediatric and Fetal Echocardiography Laboratory, New York University School of Medicine, New York, NY 10016, USA
Pharos Alpha Omega Alpha Honor Med Soc 69:38-9. 2006
Embryonic heart failure in NFATc1-/- mice: novel mechanistic insights from in utero ultrasound biomicroscopyColin K L Phoon
Pediatric Cardiology Program, New York University School of Medicine, New York, NY, USA
Circ Res 95:92-9. 2004..This study is among the first linking a specific physiological phenotype with a defined genotype, and demonstrates that NFATc1-/- embryonic heart failure is a complex phenomenon not simply attributable to contractile dysfunction...
Spatial velocity profile in mouse embryonic aorta and Doppler-derived volumetric flow: a preliminary modelColin K L Phoon
Pediatric Cardiology Program, New York University School of Medicine, New York, New York 10016, USA
Am J Physiol Heart Circ Physiol 283:H908-16. 2002..As a first approximation, these results are an important step toward precise in utero ultrasound characterization of blood flow within the developing mammalian circulation...
Circulatory physiology in the developing embryoC K Phoon
Pediatric Cardiology Program, New York University School of Medicine, New York, New York 10016, USA
Curr Opin Pediatr 13:456-64. 2001..The next major challenges include understanding the mechanisms regulating cardiovascular hemodynamics, normal physiologic adaptation of the growing embryo, and the physiology of abnormal cardiovascular development...
Estimation of pressure gradients by auscultation: an innovative and accurate physical examination techniqueC K Phoon
New York University School of Medicine, Pediatric Cardiology Program, NYU Medical Center, 540 First Ave, New York, NY 10016, USA
Am Heart J 141:500-6. 2001..Knowledge of pressure gradients across valves, arteries, and ventricular septal defects (VSD) is important in patient management. It was determined how well such gradients can be estimated by auscultation of a murmur's frequencies...
40 MHz Doppler characterization of umbilical and dorsal aortic blood flow in the early mouse embryoC K Phoon
Pediatric Cardiology Program, New York University School of Medicine, New York, New York, USA
Ultrasound Med Biol 26:1275-83. 2000..High-frequency PW Doppler is a powerful tool for the quantitative, noninvasive investigation of early mouse circulatory development...
Onset of cardiac function during early mouse embryogenesis coincides with entry of primitive erythroblasts into the embryo properRui Ping Ji
Skirball Institute of Biomolecular Medicine, New York University School of Medicine, New York, NY, USA
Circ Res 92:133-5. 2003..In situ hybridization revealed an onset of the heartbeat coincident with the appearance of yolk sac-derived erythroblasts in the embryo proper at 5 S. Early maturation of the circulation follows a tightly coordinated program...
Noninvasive localization of nuclear factor of activated T cells c1-/- mouse embryos by ultrasound biomicroscopy-Doppler allows genotype-phenotype correlationRui Ping Ji
Pediatric Cardiology Program, New York University School of Medicine, New York, New York, USA
J Am Soc Echocardiogr 18:1415-21. 2005..Noninvasive localization and UBM-Doppler analysis of in situ mouse embryos can provide accurate genotype-phenotype correlation, along with nontraumatic serial imaging of embryos...
Expression of a sorcin missense mutation in the heart modulates excitation-contraction couplingLeon P Collis
Division of Pediatric Cardiology, New York University School of Medicine, New York, NY 10016, USA
FASEB J 21:475-87. 2007..Our results also suggest that additional factors may be responsible for the development of cardiac hypertrophy and hypertension in humans expressing the L112-sorcin sequence variant...
Research Grants
- Doppler characterization of embryonic mouse circulationColin Phoon; Fiscal Year: 2005..abstract_text> ..
