Affiliation: New Jersey
- 5'-end surveillance by Xrn2 acts as a shared mechanism for mammalian pre-rRNA maturation and decayMinshi Wang
Department of Cell Biology, University of Medicine and Dentistry of New Jersey, Stratford, NJ 08084, USA
Nucleic Acids Res 39:1811-22. 2011..We propose that probing of pre-rRNA maturation intermediates by exonucleases serves the dual function of generating mature rRNAs and suppressing suboptimal processing paths during ribosome assembly...
- Rapid cytoplasmic turnover of yeast ribosomes in response to rapamycin inhibition of TORDimitri G Pestov
Department of Cell Biology, University of Medicine and Dentistry of New Jersey, Stratford, New Jersey, USA
Mol Cell Biol 32:2135-44. 2012..We propose that ribosome content is regulated dynamically in eukaryotes by TOR through both ribosome synthesis and the cytoplasmic turnover of mature ribosomes...
- Mammalian DEAD box protein Ddx51 acts in 3' end maturation of 28S rRNA by promoting the release of U8 snoRNALeena Srivastava
Department of Cell Biology, University of Medicine and Dentistry of New Jersey, 2 Medical Center Drive, Stratford, NJ 08084, USA
Mol Cell Biol 30:2947-56. 2010..These data demonstrate the emergence of a novel factor that facilitates a pre-rRNA processing event specific for higher eukaryotes...