Zhiheng Pei

Summary

Affiliation: New York University
Country: USA

Publications

  1. pmc Bacterial biota in the human distal esophagus
    Zhiheng Pei
    Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
    Proc Natl Acad Sci U S A 101:4250-5. 2004
  2. pmc Molecular analysis of human forearm superficial skin bacterial biota
    Zhan Gao
    Department of Medicine, New York University School of Medicine, New York, NY 10016, USA
    Proc Natl Acad Sci U S A 104:2927-32. 2007
  3. pmc Bacterial biota in reflux esophagitis and Barrett's esophagus
    Zhiheng Pei
    Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
    World J Gastroenterol 11:7277-83. 2005
  4. pmc Molecular pathways: pathogenesis and clinical implications of microbiome alteration in esophagitis and Barrett esophagus
    Liying Yang
    Department of Medicine and Pathology, New York University School of Medicine, New York, New York 10010, USA
    Clin Cancer Res 18:2138-44. 2012
  5. pmc Association between selected oral pathogens and gastric precancerous lesions
    Christian R Salazar
    Department of Epidemiology and Health Promotion, New York University College of Dentistry, New York, NY, USA
    PLoS ONE 8:e51604. 2013
  6. pmc Substantial alterations of the cutaneous bacterial biota in psoriatic lesions
    Zhan Gao
    Department of Medicine, New York University School of Medicine, New York, New York, United States of America
    PLoS ONE 3:e2719. 2008
  7. pmc The effect of H. pylori eradication on meal-associated changes in plasma ghrelin and leptin
    Fritz Francois
    New York University Langone Medical Center, New York, NY, USA
    BMC Gastroenterol 11:37. 2011
  8. pmc Diversity of 5S rRNA genes within individual prokaryotic genomes
    Anna Pei
    New York University College of Arts and Science, New York, NY, USA
    FEMS Microbiol Lett 335:11-8. 2012
  9. doi request reprint Human microbiome and HIV/AIDS
    Deepak Saxena
    Department of Basic Science and Craniofacial Biology, New York University College of Dentistry, New York, NY, USA
    Curr HIV/AIDS Rep 9:44-51. 2012
  10. pmc Association between oral health and gastric precancerous lesions
    Christian R Salazar
    Department of Epidemiology and Health Promotion, New York University College of Dentistry, New York, NY 10003, USA
    Carcinogenesis 33:399-403. 2012

Collaborators

Detail Information

Publications21

  1. pmc Bacterial biota in the human distal esophagus
    Zhiheng Pei
    Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
    Proc Natl Acad Sci U S A 101:4250-5. 2004
    ..These findings provide evidence for a complex but conserved bacterial population in the normal distal esophagus...
  2. pmc Molecular analysis of human forearm superficial skin bacterial biota
    Zhan Gao
    Department of Medicine, New York University School of Medicine, New York, NY 10016, USA
    Proc Natl Acad Sci U S A 104:2927-32. 2007
    ..4% of all clones. These results show that the bacterial biota in normal superficial skin is highly diverse, with few well conserved and well represented genera, but otherwise low-level interpersonal consensus...
  3. pmc Bacterial biota in reflux esophagitis and Barrett's esophagus
    Zhiheng Pei
    Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
    World J Gastroenterol 11:7277-83. 2005
    ..To identify the bacterial flora in conditions such as Barrettos esophagus and reflux esophagitis to determine if they are similar to normal esophageal flora...
  4. pmc Molecular pathways: pathogenesis and clinical implications of microbiome alteration in esophagitis and Barrett esophagus
    Liying Yang
    Department of Medicine and Pathology, New York University School of Medicine, New York, New York 10010, USA
    Clin Cancer Res 18:2138-44. 2012
    ....
  5. pmc Association between selected oral pathogens and gastric precancerous lesions
    Christian R Salazar
    Department of Epidemiology and Health Promotion, New York University College of Dentistry, New York, NY, USA
    PLoS ONE 8:e51604. 2013
    ..03-0.06). Among individuals with periodontal disease, high levels of colonization of periodontal pathogens are associated with an increased risk of gastric precancerous lesions...
  6. pmc Substantial alterations of the cutaneous bacterial biota in psoriatic lesions
    Zhan Gao
    Department of Medicine, New York University School of Medicine, New York, New York, United States of America
    PLoS ONE 3:e2719. 2008
    ..001), whereas normal skin from the psoriatic patients showed intermediate levels (12.3+/-21.6%). We conclude that psoriasis is associated with substantial alteration in the composition and representation of the cutaneous bacterial biota...
  7. pmc The effect of H. pylori eradication on meal-associated changes in plasma ghrelin and leptin
    Fritz Francois
    New York University Langone Medical Center, New York, NY, USA
    BMC Gastroenterol 11:37. 2011
    ..pylori colonization. We prospectively evaluated the effect of H. pylori eradication on meal-associated changes in serum ghrelin and leptin levels, and body weight...
  8. pmc Diversity of 5S rRNA genes within individual prokaryotic genomes
    Anna Pei
    New York University College of Arts and Science, New York, NY, USA
    FEMS Microbiol Lett 335:11-8. 2012
    ..In total, these findings indicated that there are tight ribosomal constraints on paralogous 5S rRNA genes in a genome despite of the high degree of diversity at the primary structure level...
  9. doi request reprint Human microbiome and HIV/AIDS
    Deepak Saxena
    Department of Basic Science and Craniofacial Biology, New York University College of Dentistry, New York, NY, USA
    Curr HIV/AIDS Rep 9:44-51. 2012
    ....
  10. pmc Association between oral health and gastric precancerous lesions
    Christian R Salazar
    Department of Epidemiology and Health Promotion, New York University College of Dentistry, New York, NY 10003, USA
    Carcinogenesis 33:399-403. 2012
    ..7%)], independent of potential confounders. Our findings demonstrate that specific oral health conditions and behaviors such as gingival bleeding and tooth flossing are associated with gastric precancerous lesions...
  11. pmc Design of 16S rRNA gene primers for 454 pyrosequencing of the human foregut microbiome
    Carlos W Nossa
    Department of Veterans Affairs New York Harbor Health System, 423 E 23rd Street, New York, NY 10010, USA
    World J Gastroenterol 16:4135-44. 2010
    ..To design and validate broad-range 16S rRNA primers for use in high throughput sequencing to classify bacteria isolated from the human foregut microbiome...
  12. pmc Inflammation and intestinal metaplasia of the distal esophagus are associated with alterations in the microbiome
    Liying Yang
    Department of Pathology, New York University School of Medicine, New York, New York, USA
    Gastroenterology 137:588-97. 2009
    ..This is the first comprehensive reported correlation between a change in the esophageal microbiome and esophageal diseases...
  13. pmc Leptin and ghrelin in relation to Helicobacter pylori status in adult males
    Jatin Roper
    New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    J Clin Endocrinol Metab 93:2350-7. 2008
    ..Leptin and ghrelin, hormones involved in human energy homeostasis, are both produced in the stomach...
  14. pmc Diversity of 16S rRNA genes within individual prokaryotic genomes
    Anna Y Pei
    New York University College of Arts and Science, New York, New York 10012, USA
    Appl Environ Microbiol 76:3886-97. 2010
    ..This phenomenon is especially seen in 7 bacterial species associated with the human microbiome or diseases...
  15. pmc Case report: Paenibacillus thiaminolyticus: a new cause of human infection, inducing bacteremia in a patient on hemodialysis
    Jie Ouyang
    Department of Pathology, State University of New York, Downstate Medical Center, Brooklyn, NY 11209, USA
    Ann Clin Lab Sci 38:393-400. 2008
    ..This constitutes the first report of a human infection caused by this organism...
  16. pmc Oral microbiome profiles: 16S rRNA pyrosequencing and microarray assay comparison
    Jiyoung Ahn
    Division of Epidemiology, Department of Environmental Medicine, New York University School of Medicine, New York, New York, United States of America
    PLoS ONE 6:e22788. 2011
    ..We compared two oral microbiome survey methods: broad-based microbiome identification by 16S rRNA gene sequencing and targeted characterization of microbes by custom DNA microarray...
  17. pmc Urethral adenocarcinoma associated with intestinal-type metaplasia, case report and literature review
    Christopher S Hale
    Department of Pathology, New York Harbor Healthcare System, New York University School of Medicine New York, NY, USA
    Int J Clin Exp Pathol 6:1665-70. 2013
    ..When intestinal-type mucosa is present within a urinary tract biopsy, associated malignancy may be present only focally. Thorough sampling and consideration of the differential diagnosis is imperative. ..
  18. ncbi request reprint Androgen receptor coactivator ARA70alpha and ARA70beta isoform-specific antibodies: new tools for studies of expression and immunohistochemical localization
    Yi Peng
    Departments of Pathology, New York University School of Medicine, New York, NY 10010, USA
    Appl Immunohistochem Mol Morphol 16:7-12. 2008
    ..ARA70beta localized to the cytosol, whereas ARA70alpha was found in the nucleus, supporting the notion of their dissimilar functions...
  19. ncbi request reprint Radiographic determination of tissue thickness in paraffin blocks: application to the construction of tissue microarrays
    Xiangtian Kong
    Department of Pathology, New York University School of Medicine, New York, 10016 NY, USA
    Appl Immunohistochem Mol Morphol 15:108-12. 2007
    ..Prior knowledge of tissue thickness in TMA construction can prompt compensatory steps that can enhance the yield of valuable samples and assure sufficient numbers of adequate cores for statistical analysis in biomarker evaluations...
  20. pmc Bacterial community in the crop of the hoatzin, a neotropical folivorous flying bird
    Filipa Godoy-Vitorino
    Department of Biology, University of Puerto Rico, San Juan, Puerto Rico 00931 3360
    Appl Environ Microbiol 74:5905-12. 2008
    ..1%). The novelty in this ecosystem is great; 94% of the phylotypes were unclassified at the "species" level and thus likely include novel cellulolytic lineages...
  21. pmc Molecular analysis of sarcoidosis tissues for mycobacterium species DNA
    Wonder Puryear Drake
    Vanderbilt University School of Medicine and Veteran Affairs Medical Center, Nashville, Tennessee 37232, USA
    Emerg Infect Dis 8:1334-41. 2002
    ..tuberculosis were negative for IS6110. We provide evidence that one of a variety of Mycobacterium species, especially organisms resembling M. tuberculosis, is found in most patients with sarcoidosis...

Research Grants9

  1. Etiology & pathogenesis of chronic tonsillar hypertrophy
    Zhiheng Pei; Fiscal Year: 2009
    ..Later, we will develop a simple ELISA capable of screening a large number of patients for tonsillar antibodies to the MC-species. Addressing the three aims will provide evidence to examine the hypothesis of a bacterial etiology of CTH. ..
  2. Bacterial flora in normal esophagus & reflux disorders
    Zhiheng Pei; Fiscal Year: 2005
    ..ii) While GERD initially results from chemical damage, bacterial overgrowth may promote intestinal metaplasia of the esophagus. The proposed study allows qualitative and quantitative examination of this hypothesis. ..
  3. Etiology & pathogenesis of chronic tonsillar hypertrophy
    Zhiheng Pei; Fiscal Year: 2007
    ..Later, we will develop a simple ELISA capable of screening a large number of patients for tonsillar antibodies to the MC-species. Addressing the three aims will provide evidence to examine the hypothesis of a bacterial etiology of CTH. ..