Elizabeth Nardin

Summary

Affiliation: New York University School of Medicine
Country: USA

Publications

  1. pmc Sporozoite neutralizing antibodies elicited in mice and rhesus macaques immunized with a Plasmodium falciparum repeat peptide conjugated to meningococcal outer membrane protein complex
    Craig Przysiecki
    Vaccines Research, Merck Research Laboratories, West Point PA, USA
    Front Cell Infect Microbiol 2:146. 2012
  2. ncbi request reprint The past decade in malaria synthetic peptide vaccine clinical trials
    Elizabeth Nardin
    Department of Medical Parasitology, New York University School of Medicine, New York, NY, USA
    Hum Vaccin 6:27-38. 2010
  3. pmc Protective humoral immunity elicited by a needle-free malaria vaccine comprised of a chimeric Plasmodium falciparum circumsporozoite protein and a Toll-like receptor 5 agonist, flagellin
    Daniel Carapau
    Department of Microbiology, Division of Medical Parasitology, New York University School of Medicine, New York, New York, USA
    Infect Immun 81:4350-62. 2013
  4. pmc Enhanced immunogenicity of Plasmodium falciparum peptide vaccines using a topical adjuvant containing a potent synthetic Toll-like receptor 7 agonist, imiquimod
    Caroline Othoro
    Department of Medical Parasitology, New York University Cancer Institute, School of Medicine, New York University, New York, New York 10010, USA
    Infect Immun 77:739-48. 2009
  5. pmc Imaging effector functions of human cytotoxic CD4+ T cells specific for Plasmodium falciparum circumsporozoite protein
    Ute Frevert
    Department of Medical Parasitology, New York University School of Medicine, 341 E 25 St, New York, NY 10010, USA
    Int J Parasitol 39:119-32. 2009
  6. ncbi request reprint Cutting edge: a new tool to evaluate human pre-erythrocytic malaria vaccines: rodent parasites bearing a hybrid Plasmodium falciparum circumsporozoite protein
    Cathrine Persson
    Michael Heidelberger Division of Immunology, Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
    J Immunol 169:6681-5. 2002
  7. ncbi request reprint Quantitative Plasmodium sporozoite neutralization assay (TSNA)
    Kota Arun Kumar
    Michael Heidelberger Division of Immunology, Department of Pathology, MSB, 131, New York University School of Medicine, 550, First Avenue, New York, NY 10016, USA
    J Immunol Methods 292:157-64. 2004
  8. ncbi request reprint Sporozoite antigens: biology and immunology of the circumsporozoite protein and thrombospondin-related anonymous protein
    Photini Sinnis
    Department of Medical and Molecular Parasitology, New York University School of Medicine, New York, N Y, USA
    Chem Immunol 80:70-96. 2002
  9. doi request reprint Cellular effector mechanisms against Plasmodium liver stages
    Ute Frevert
    Department of Medical Parasitology, New York University School of Medicine, 341 E 25 St, New York, NY 10010, USA
    Cell Microbiol 10:1956-67. 2008
  10. ncbi request reprint Arrest in the liver--a genetically defined malaria vaccine?
    Ute Frevert
    Department of Medical and Molecular Parasitology, New York University School of Medicine, New York, USA
    N Engl J Med 352:1600-2. 2005

Collaborators

Detail Information

Publications10

  1. pmc Sporozoite neutralizing antibodies elicited in mice and rhesus macaques immunized with a Plasmodium falciparum repeat peptide conjugated to meningococcal outer membrane protein complex
    Craig Przysiecki
    Vaccines Research, Merck Research Laboratories, West Point PA, USA
    Front Cell Infect Microbiol 2:146. 2012
    ..Potential pre-erythrocytic vaccines can be combined with sexual blood stage vaccines as a multi-antigen malaria vaccine to block invasion and transmission of Plasmodium parasites...
  2. ncbi request reprint The past decade in malaria synthetic peptide vaccine clinical trials
    Elizabeth Nardin
    Department of Medical Parasitology, New York University School of Medicine, New York, NY, USA
    Hum Vaccin 6:27-38. 2010
    ..Additional challenges include the need for potent adjuvants for the development of synthetic peptide vaccines that can effectively target multiple stages of the Plasmodium parasite...
  3. pmc Protective humoral immunity elicited by a needle-free malaria vaccine comprised of a chimeric Plasmodium falciparum circumsporozoite protein and a Toll-like receptor 5 agonist, flagellin
    Daniel Carapau
    Department of Microbiology, Division of Medical Parasitology, New York University School of Medicine, New York, New York, USA
    Infect Immun 81:4350-62. 2013
    ..n. immunization with a flagellin-modified P. falciparum CS protein and raise the potential of a scalable, safe, needle-free vaccine for the 40% of the world's population at risk of malaria. ..
  4. pmc Enhanced immunogenicity of Plasmodium falciparum peptide vaccines using a topical adjuvant containing a potent synthetic Toll-like receptor 7 agonist, imiquimod
    Caroline Othoro
    Department of Medical Parasitology, New York University Cancer Institute, School of Medicine, New York University, New York, New York 10010, USA
    Infect Immun 77:739-48. 2009
    ....
  5. pmc Imaging effector functions of human cytotoxic CD4+ T cells specific for Plasmodium falciparum circumsporozoite protein
    Ute Frevert
    Department of Medical Parasitology, New York University School of Medicine, 341 E 25 St, New York, NY 10010, USA
    Int J Parasitol 39:119-32. 2009
    ....
  6. ncbi request reprint Cutting edge: a new tool to evaluate human pre-erythrocytic malaria vaccines: rodent parasites bearing a hybrid Plasmodium falciparum circumsporozoite protein
    Cathrine Persson
    Michael Heidelberger Division of Immunology, Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
    J Immunol 169:6681-5. 2002
    ..Monoclonal and polyclonal Abs to P. falciparum repeats neutralize hybrid parasite infectivity, and mice immunized with a P. falciparum vaccine are protected against challenge with hybrid sporozoites...
  7. ncbi request reprint Quantitative Plasmodium sporozoite neutralization assay (TSNA)
    Kota Arun Kumar
    Michael Heidelberger Division of Immunology, Department of Pathology, MSB, 131, New York University School of Medicine, 550, First Avenue, New York, NY 10016, USA
    J Immunol Methods 292:157-64. 2004
    ..175) when analyzed by non-parametric Spearman correlation method. Ongoing human trials of CS-based vaccines should provide an opportunity to determine whether TSNAs will provide better correlates of protective immunity than ELISA assays...
  8. ncbi request reprint Sporozoite antigens: biology and immunology of the circumsporozoite protein and thrombospondin-related anonymous protein
    Photini Sinnis
    Department of Medical and Molecular Parasitology, New York University School of Medicine, New York, N Y, USA
    Chem Immunol 80:70-96. 2002
  9. doi request reprint Cellular effector mechanisms against Plasmodium liver stages
    Ute Frevert
    Department of Medical Parasitology, New York University School of Medicine, 341 E 25 St, New York, NY 10010, USA
    Cell Microbiol 10:1956-67. 2008
    ..Considering the unique immune properties of the liver, it is conceivable that these different hepatic antigen-presenting cells fulfil distinct but complementary roles during the effector phase against Plasmodium liver stages...
  10. ncbi request reprint Arrest in the liver--a genetically defined malaria vaccine?
    Ute Frevert
    Department of Medical and Molecular Parasitology, New York University School of Medicine, New York, USA
    N Engl J Med 352:1600-2. 2005