Alicia M Mohr

Summary

Affiliation: New Jersey
Country: USA

Publications

  1. ncbi request reprint The role of dead space ventilation in predicting outcome of successful weaning from mechanical ventilation
    A M Mohr
    Department of Surgery, Section of Critical Care, University of North Carolina, Chapel Hill, North Carolina, USA
    J Trauma 51:843-8. 2001
  2. pmc Recombinant activated factor VIIa and hemostasis in critical care: a focus on trauma
    Alicia M Mohr
    Department of Surgery, New Jersey Medical School, Newark, New Jersey, USA
    Crit Care 9:S37-42. 2005
  3. ncbi request reprint Use of aerosolized aminoglycosides in the treatment of Gram-negative ventilator-associated pneumonia
    Alicia M Mohr
    Division of Trauma Critical Care, Department of Surgery, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, New Jersey 07103, USA
    Surg Infect (Larchmt) 8:349-57. 2007
  4. ncbi request reprint Level systems: inpatient programming whose time has passed
    Wanda K Mohr
    Psychiatric Mental Health Nursing, University of Medicine and Dentistry, Newark, NJ, USA
    J Child Adolesc Psychiatr Nurs 17:113-25. 2004
  5. pmc Does beta blockade postinjury prevent bone marrow suppression?
    Alicia M Mohr
    Division of Trauma, Department of Surgery, UMDNJ New Jersey Medical School, Newark, New Jersey 07103, USA
    J Trauma 70:1043-9; discussion 1049-50. 2011
  6. ncbi request reprint Angiographic embolization for liver injuries: low mortality, high morbidity
    Alicia M Mohr
    Department of Surgery, University of Medicine and Dentistry of New Jersey New Jersey Medcial School, Newark, 07103, USA
    J Trauma 55:1077-81; discussion 1081-2. 2003
  7. ncbi request reprint Management of trauma to the male external genitalia: the usefulness of American Association for the Surgery of Trauma organ injury scales
    Alicia M Mohr
    Department of Surgery, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark 07103, USA
    J Urol 170:2311-5. 2003
  8. ncbi request reprint Gender differences in glucose variability after severe trauma
    Alicia M Mohr
    Department of Surgery, UMDNJ New Jersey Medical School, Newark, New Jersey 07103, USA
    Am Surg 76:896-902. 2010
  9. ncbi request reprint Sex hormones affect bone marrow dysfunction after trauma and hemorrhagic shock
    Ziad C Sifri
    Division of Trauma, Department of Surgery, New Jersey Medical School, Newark, NJ, USA
    Crit Care Med 35:864-9. 2007
  10. pmc β-blockade protection of bone marrow following trauma: the role of G-CSF
    Gregg M Baranski
    Department of Surgery, Division of Trauma, University of Medicine and Dentistry of New Jersey UMDNJ New Jersey Medical School, Newark, New Jersey 07103, USA
    J Surg Res 170:325-31. 2011

Research Grants

Collaborators

Detail Information

Publications36

  1. ncbi request reprint The role of dead space ventilation in predicting outcome of successful weaning from mechanical ventilation
    A M Mohr
    Department of Surgery, Section of Critical Care, University of North Carolina, Chapel Hill, North Carolina, USA
    J Trauma 51:843-8. 2001
    ..Theoretically, tracheostomy should reduce dead space ventilation and improve pulmonary mechanics, thereby facilitating weaning from mechanical ventilation...
  2. pmc Recombinant activated factor VIIa and hemostasis in critical care: a focus on trauma
    Alicia M Mohr
    Department of Surgery, New Jersey Medical School, Newark, New Jersey, USA
    Crit Care 9:S37-42. 2005
    ..Further prospective, randomized, and placebo-controlled clinical trials will yield more information on the role of rFVIIa in the management of traumatic bleeding...
  3. ncbi request reprint Use of aerosolized aminoglycosides in the treatment of Gram-negative ventilator-associated pneumonia
    Alicia M Mohr
    Division of Trauma Critical Care, Department of Surgery, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, New Jersey 07103, USA
    Surg Infect (Larchmt) 8:349-57. 2007
    ..This study examined the role of aerosolized aminoglycosides in the treatment of VAP in surgical ICU patients...
  4. ncbi request reprint Level systems: inpatient programming whose time has passed
    Wanda K Mohr
    Psychiatric Mental Health Nursing, University of Medicine and Dentistry, Newark, NJ, USA
    J Child Adolesc Psychiatr Nurs 17:113-25. 2004
    ..Structuring of inpatient behavioral programming in child-adolescent psychiatric, residential treatment, and juvenile justice settings...
  5. pmc Does beta blockade postinjury prevent bone marrow suppression?
    Alicia M Mohr
    Division of Trauma, Department of Surgery, UMDNJ New Jersey Medical School, Newark, New Jersey 07103, USA
    J Trauma 70:1043-9; discussion 1049-50. 2011
    ..In a clinically relevant model, this study examines the effect of BB given after both tissue injury and hemorrhagic shock (HS)...
  6. ncbi request reprint Angiographic embolization for liver injuries: low mortality, high morbidity
    Alicia M Mohr
    Department of Surgery, University of Medicine and Dentistry of New Jersey New Jersey Medcial School, Newark, 07103, USA
    J Trauma 55:1077-81; discussion 1081-2. 2003
    ..This study examines further the role of AE in both blunt and penetrating liver injuries and the outcomes of its use...
  7. ncbi request reprint Management of trauma to the male external genitalia: the usefulness of American Association for the Surgery of Trauma organ injury scales
    Alicia M Mohr
    Department of Surgery, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark 07103, USA
    J Urol 170:2311-5. 2003
    ..To assist in defining the indications for nonoperative management the usefulness of the American Association for the Surgery of Trauma (AAST) organ injury scales for these injuries was examined...
  8. ncbi request reprint Gender differences in glucose variability after severe trauma
    Alicia M Mohr
    Department of Surgery, UMDNJ New Jersey Medical School, Newark, New Jersey 07103, USA
    Am Surg 76:896-902. 2010
    ..In females, mortality cannot be predicted based on BG levels or BG variability. These data have significant implications for gender-related differences in postinjury management...
  9. ncbi request reprint Sex hormones affect bone marrow dysfunction after trauma and hemorrhagic shock
    Ziad C Sifri
    Division of Trauma, Department of Surgery, New Jersey Medical School, Newark, NJ, USA
    Crit Care Med 35:864-9. 2007
    ..Therefore, the present study examines the effects of sex hormones on post-T/HS BM dysfunction by measuring clonogenic growth of BM progenitors in castrated male rats and in ovariectomized and proestrus female rats...
  10. pmc β-blockade protection of bone marrow following trauma: the role of G-CSF
    Gregg M Baranski
    Department of Surgery, Division of Trauma, University of Medicine and Dentistry of New Jersey UMDNJ New Jersey Medical School, Newark, New Jersey 07103, USA
    J Surg Res 170:325-31. 2011
    ..When sustained, this depletion of BM cellularity may contribute to BM failure. This study seeks to determine if G-CSF plays a role in the βB protection of BM following trauma...
  11. ncbi request reprint Bone marrow failure in male rats following trauma/hemorrhagic shock (T/HS) is mediated by mesenteric lymph and modulated by castration
    Ziad C Sifri
    Division of Trauma, Department of Surgery, New Jersey Medical School, Newark, NJ 07103, USA
    Shock 25:12-6. 2006
    ..Further studies are needed to elucidate potential therapeutic effects of lymph manipulation in hematopoiesis after injury...
  12. ncbi request reprint Civilian craniocerebral gunshot wounds: an update in predicting outcomes
    Tiffany Murano
    Department of Surgery, Division of Emergency Medicine, UMDNJ New Jersey Medical School, Newark, New Jersey 07103, USA
    Am Surg 71:1009-14. 2005
    ..This is not only important in determining treatment algorithms for physicians but also for appropriate counseling of family members to educate them with regard to patients' outcomes...
  13. doi request reprint Hematopoietic progenitor cell mobilization is mediated through beta-2 and beta-3 receptors after injury
    Keith A Beiermeister
    Division of Trauma, Department of Surgery, UMDNJ New Jersey Medical School, Newark, New Jersey 07103, USA
    J Trauma 69:338-43. 2010
    ..Given the vast physiologic effects of nonselective BB, the aim of this study is to delineate the role of selective BB in HPC growth and mobilization...
  14. ncbi request reprint Do all β-blockers attenuate the excess hematopoietic progenitor cell mobilization from the bone marrow following trauma/hemorrhagic shock?
    Latha V Pasupuleti
    From the Division of Trauma, Department of Surgery, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey
    J Trauma Acute Care Surg 76:970-5. 2014
    ..This study will determine the role of selective β-adrenergic receptor blockade in HPC mobilization in a combined model of lung contusion (LC) and HS...
  15. ncbi request reprint Obesity does not increase morbidity and mortality after laparotomy for trauma
    David H Livingston
    New Jersey Trauma Center, Division of Trauma, Department of Surgery, New Jersey Medical School, Newark, New Jersey, USA
    Am Surg 79:247-52. 2013
    ..Although obese trauma patients do have increased infectious morbidity, wound dehiscence, and a prolonged length of stay, increased BMI is not an independent predictor of increased morbidity or mortality after trauma laparotomy...
  16. pmc The role of plasma granulocyte colony stimulating factor and bone marrow dysfunction after severe trauma
    Kristin M Cook
    Department of Surgery, Division of Trauma, New Jersey Medical School, Newark, NJ, USA
    J Am Coll Surg 216:57-64. 2013
    ..Granulocyte colony stimulating factor (G-CSF) is a potent stimulator of HPC mobilization. We hypothesized that plasma G-CSF levels are elevated after trauma and correlate with postinjury anemia and infection...
  17. doi request reprint Is the sympathetic system involved in shock-induced gut and lung injury?
    Gregg M Baranski
    Division of Trauma, Department of Surgery, New Jersey Medical School, University of Medicine and Dentistry, Newark, New Jersey 07103, USA
    J Trauma Acute Care Surg 73:343-50; discussion 350. 2012
    ..The impact of the sympathetic system and the role of BB on shock-induced distant organ injury is not known. This study will determine if BB has systemic effects and can diminish gut and lung injury after trauma and HS...
  18. pmc Beta-blockade prevents hematopoietic progenitor cell suppression after hemorrhagic shock
    Ihab O ElHassan
    Department of Surgery, Division of Trauma, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, New Jersey 07103, USA
    Surg Infect (Larchmt) 12:273-8. 2011
    ..This study examined the effect and timing of BB on BM function in a hemorrhagic shock (HS) model...
  19. ncbi request reprint The impact of a hypercatecholamine state on erythropoiesis following severe injury and the role of IL-6
    Rodrigo B Fonseca
    Department of Surgery, UMDNJ New Jersey Medical School, Newark, 07103, USA
    J Trauma 59:884-9; discussion 889-90. 2005
    ..The aim of this study was to investigate the severity of a hyper-adrenergic stimulus on pluripotent progenitors (GEMM-CFU) as well as erythroid progenitors (BFU-E and CFU-E) and the potential regulatory role of IL-6...
  20. doi request reprint Neurologic outcome of minimal head injury patients managed with or without a routine repeat head computed tomography
    Natasha V Nayak
    Division of Trauma and Critical Care, Department of Surgery, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, New Jersey 07103, USA
    J Trauma Acute Care Surg 75:273-8. 2013
    ..The goal of this study was to compare the neurologic outcomes of MHI patients with an intracranial bleed and a normal NE who were managed with or without a routine RHCT...
  21. doi request reprint Mobilization of bone marrow cells to the site of injury is necessary for wound healing
    Salil Shah
    Division of Trauma, Department of Surgery, UMDNJ New Jersey Medical School, Newark, New Jersey, USA
    J Trauma 67:315-21; discussion 321-2. 2009
    ..Postinjury mesenteric lymph has been shown to cause early organ failure. Thus, we hypothesized that diversion of mesenteric lymph would improve early organ dysfunction through decreased mobilization of BM HPC to the lung...
  22. ncbi request reprint Hematopoietic progenitor cells mobilize to the site of injury after trauma and hemorrhagic shock in rats
    Chirag D Badami
    Department of Surgery, New Jersey Medical School, Newark, NJ, USA
    J Trauma 63:596-600; discussion 600-2. 2007
    ..We investigated the hypothesis that HPC will specifically migrate to sites of tissue trauma and that this process is exacerbated by hemorrhagic shock (HS)...
  23. doi request reprint Transfusion begets anemia: the effect of aged blood on hematopoiesis
    Kimberly J Song
    From the Division of Trauma, Department of Surgery, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey
    J Trauma Acute Care Surg 75:984-9. 2013
    ..The effects of aged blood on bone marrow (BM) hematopoiesis have not been studied, and we hypothesized that stored blood suppresses BM function...
  24. pmc Does selective beta-1 blockade provide bone marrow protection after trauma/hemorrhagic shock?
    Latha V Pasupuleti
    Division of Trauma, Department of Surgery, UMDNJ New Jersey Medical School, Newark, NJ, USA
    Surgery 152:322-30. 2012
    ..Because selective beta-1 blockers are used commonly for their cardiac protection, the aim of this study was to more clearly define the role of specific beta adrenergic receptors in BM protection after trauma and HS...
  25. pmc Dose-response relationship between norepinephrine and erythropoiesis: evidence for a critical threshold
    Angela Penn
    Department of Surgery, Division of Trauma University of Medicine and Dentistry New Jersey UMDNJ New Jersey Medical School, Newark, New Jersey, USA
    J Surg Res 163:e85-90. 2010
    ..Our previous work suggests that norepinephrine (NE) influences the bone marrow (BM) erythropoietic response. However, the dose-response relationship between NE and erythropoiesis remains unclear...
  26. ncbi request reprint Small volume albumin administration protects against hemorrhagic shock-induced bone marrow dysfunction
    Adena J Osband
    Division of Trauma, Department of Surgery, New Jersey Medical School, Newark, New Jersey 07103, USA
    J Trauma 56:279-83. 2004
    ..Unexpected immunomodulatory effects of colloids and crystalloids prompted an investigation of albumin's ability to prevent bone marrow (BM) suppression following trauma/hemorrhagic shock (T/HS: laparotomy + MAP 30 for 90 mins)...
  27. ncbi request reprint Value of repeat cranial computed axial tomography scanning in patients with minimal head injury
    Ziad C Sifri
    Division of Trauma, Department of Surgery, University of Medicine and Dentistry of New Jersey New Jersey Medical School, University Hospital M 243, 150 Bergen St, Newark, NJ 07103, USA
    Am J Surg 187:338-42. 2004
    ..The value of this repeat cranial CAT scan is unclear in those patients who are neurologically normal or improving...
  28. ncbi request reprint Adrenergic modulation of erythropoiesis following severe injury is mediated through bone marrow stroma
    Rodrigo B Fonseca
    Department of Surgery, Division of Trauma, UMDNJ New Jersey Medical School, Newark, NJ 07103, USA
    Surg Infect (Larchmt) 5:385-93. 2004
    ..The aim of this study was to demonstrate the effects of adrenergic agonists and antagonists on erythropoiesis, both in normal bone marrow mononuclear cells (BMNC) and stroma-depleted BM...
  29. ncbi request reprint Impact of enhanced mobilization of bone marrow derived cells to site of injury
    Edward J Hannoush
    Division of Trauma, Department of Surgery, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, New Jersey, USA
    J Trauma 71:283-9; discussion 289-91. 2011
    ..We also postulated that increased homing of MSC alone to sites of injury would also improve tissue healing...
  30. ncbi request reprint Early propranolol administration to severely injured patients can improve bone marrow dysfunction
    Letitia E Bible
    From the Division of Trauma, Department of Surgery, Rutgers New Jersey Medical School, Newark, New Jersey
    J Trauma Acute Care Surg 77:54-60. 2014
    ..We have previously shown that propranolol (β-blocker [BB]) reduces HPC mobilization in a rodent model of injury and hemorrhagic shock. We hypothesize that BB would prevent BM dysfunction in humans following severe injury...
  31. doi request reprint Beyond point and level systems: moving toward child-centered programming
    Wanda K Mohr
    Child Adolescent Psychiatric Advanced Practice Nursing, University of Medicine and Dentistry, New Jersey, School of Nursing, Stratford, NJ 08084, USA
    Am J Orthopsychiatry 79:8-18. 2009
    ..Finally, the authors describe a different approach to providing treatment that is based on a collaborative problem-solving approach and upon which other successful models of treatment have been based...
  32. ncbi request reprint Bacteremia and ventilator-associated pneumonia: a marker for contemporaneous extra-pulmonic infection
    Anastasia Kunac
    1 Department of Surgery, Division of Trauma, Rutgers New Jersey Medical School, Newark, New Jersey
    Surg Infect (Larchmt) 15:77-83. 2014
    ..The goal of this study was to examine the incidence, predictors, and outcome of B-VAP in adult trauma patients...
  33. doi request reprint Haemorrhagic shock therapy
    Devashish J Anjaria
    UMDNJ New Jersey Medical School, Department of Surgery, Newark, NJ 07101, USA
    Expert Opin Pharmacother 9:901-11. 2008
    ..Care of the injured patient in shock involves an overlapping continuum of care beginning during the prehospital phase of care and extending through the interventional and critical care phases...
  34. ncbi request reprint Is extended antibiotic prophylaxis necessary after penetrating trauma to the thoracolumbar spine with concomitant intraperitoneal injuries?
    Latha V Pasupuleti
    Department of Surgery, Division of Trauma, Rutgers New Jersey Medical School, Newark, New Jersey
    Surg Infect (Larchmt) 15:8-13. 2014
    ..There is insufficient evidence to support the use of prolonged antibiotic prophylaxis to prevent spine infection in patients with penetrating abdominal trauma and TLS fracture. ..
  35. ncbi request reprint Delayed differentiation of HL-60 cells following exposure to hypoxia
    Xiaosong Song
    Department of Medicine, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, 07103, USA
    J Surg Res 108:243-9. 2002
    ..In this study, we examined if this defect is at the stage of terminal differentiation with the myelomonocytic cell line HL-60...
  36. doi request reprint Still shackled in the land of liberty: denying children the right to be safe from abusive "treatment"
    Wanda K Mohr
    University of Medicine and Dentistry, New Jersey School of Nursing, 40 East Laurel Rd, Stratford, NJ 08084, USA
    ANS Adv Nurs Sci 32:173-85. 2009
    ..Suggestions for action by nurses are proposed that could protect vulnerable children against this continuous cycle of institutionalized child abuse masquerading as therapy...

Research Grants2

  1. Neuroendocrine regulation of erythropoiesis following trauma
    Alicia Mohr; Fiscal Year: 2007
    ..This proposal is novel and understanding the neuroendocrine mechanism of erythropoiesis following trauma is a preliminary step towards potential therapeutic modalities for the treatment of anemia. ..