Khush R Mittal

Summary

Affiliation: New York University
Country: USA

Publications

  1. doi request reprint Molecular and immunohistochemical evidence for the origin of uterine leiomyosarcomas from associated leiomyoma and symplastic leiomyoma-like areas
    Khush R Mittal
    Department of Pathology, New York University School of Medicine, 462 First Avenue, New York, NY 10016, USA
    Mod Pathol 22:1303-11. 2009
  2. doi request reprint Presence of endometrial adenocarcinoma in situ in complex atypical endometrial hyperplasia is associated with increased incidence of endometrial carcinoma in subsequent hysterectomy
    Khush Mittal
    Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
    Mod Pathol 22:37-42. 2009
  3. doi request reprint Application of immunohistochemistry to gynecologic pathology
    Khush Mittal
    Department of Pathology, NYU School of Medicine and Surgical and Ob Gyn Pathology, Bellevue Hospital, Room 4 west 1, 462 First Ave, New York, NY 10016, USA
    Arch Pathol Lab Med 132:402-23. 2008
  4. ncbi request reprint Areas with benign morphologic and immunohistochemical features are associated with some uterine leiomyosarcomas
    Khush Mittal
    Department of Pathology, New York University School of Medicine, Bellevue Hospital Center, 462 First Avenue, Room 4W35, New York, NY 10016, USA
    Gynecol Oncol 104:362-5. 2007
  5. ncbi request reprint Spatial differences in biologic activity of large uterine leiomyomata
    Jian Jun Wei
    Department of Pathology, Bellevue Hospital, New York, New York, USA
    Fertil Steril 85:179-87. 2006
  6. ncbi request reprint Multiplex short tandem repeat DNA analysis confirms the accuracy of p57(KIP2) immunostaining in the diagnosis of complete hydatidiform mole
    Dorota A Popiolek
    Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
    Hum Pathol 37:1426-34. 2006
  7. ncbi request reprint Images in pathology. Invasive squamous cell carcinoma of vulva that wanted to be a puppy
    Khush Mittal
    Surgical and Ob Gyn Pathology, Bellevue Hospital, New York, NY 10016, USA
    Int J Surg Pathol 14:335. 2006
  8. ncbi request reprint Precursor lesions for uterine leiomyosarcoma
    Khush Mittal
    Hum Pathol 38:1289. 2007
  9. ncbi request reprint Endometrial hyperplasia and carcinoma in endometrial polyps: clinicopathologic and follow-up findings
    Khush Mittal
    Department of Pathology, New York University School of Medicine, New York, NY, USA
    Int J Gynecol Pathol 27:45-8. 2008
  10. doi request reprint Antiproliferative effects by Let-7 repression of high-mobility group A2 in uterine leiomyoma
    Yi Peng
    Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
    Mol Cancer Res 6:663-73. 2008

Collaborators

Detail Information

Publications31

  1. doi request reprint Molecular and immunohistochemical evidence for the origin of uterine leiomyosarcomas from associated leiomyoma and symplastic leiomyoma-like areas
    Khush R Mittal
    Department of Pathology, New York University School of Medicine, 462 First Avenue, New York, NY 10016, USA
    Mod Pathol 22:1303-11. 2009
    ..The immunohistochemical profiles and genetic aberrations of the examined cases suggest that uterine leiomyosarcoma could arise from the preexisting leiomyoma-like areas that often have a symplastic or cellular morphology...
  2. doi request reprint Presence of endometrial adenocarcinoma in situ in complex atypical endometrial hyperplasia is associated with increased incidence of endometrial carcinoma in subsequent hysterectomy
    Khush Mittal
    Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
    Mod Pathol 22:37-42. 2009
    ..Use of adenocarcinoma in situ terminology could lead to improved management of patients with complex atypical endometrial hyperplasia...
  3. doi request reprint Application of immunohistochemistry to gynecologic pathology
    Khush Mittal
    Department of Pathology, NYU School of Medicine and Surgical and Ob Gyn Pathology, Bellevue Hospital, Room 4 west 1, 462 First Ave, New York, NY 10016, USA
    Arch Pathol Lab Med 132:402-23. 2008
    ..Immunohistochemical stains are extremely useful in resolving many of these problematic cases. As the knowledge in this area is constantly expanding, it is useful to have this updated information in a review form for easy access...
  4. ncbi request reprint Areas with benign morphologic and immunohistochemical features are associated with some uterine leiomyosarcomas
    Khush Mittal
    Department of Pathology, New York University School of Medicine, Bellevue Hospital Center, 462 First Avenue, Room 4W35, New York, NY 10016, USA
    Gynecol Oncol 104:362-5. 2007
    ..The benign and malignant areas merged in all cases. Morphologic and immunohistochemical spectrum of changes from benign to malignant is seen in 50% of LMS. This raises the possibility of progression of some leiomyomata to LMS...
  5. ncbi request reprint Spatial differences in biologic activity of large uterine leiomyomata
    Jian Jun Wei
    Department of Pathology, Bellevue Hospital, New York, New York, USA
    Fertil Steril 85:179-87. 2006
    ..To evaluate the growth pattern of the large uterine leiomyomata (ULM), we examined the spatial gene distributions, vessel density, proliferative activity, and hyaline degeneration...
  6. ncbi request reprint Multiplex short tandem repeat DNA analysis confirms the accuracy of p57(KIP2) immunostaining in the diagnosis of complete hydatidiform mole
    Dorota A Popiolek
    Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
    Hum Pathol 37:1426-34. 2006
    ..p57(KIP2) immunohistochemistry is a time- and cost-effective means of distinguishing CHM from its mimics in challenging cases...
  7. ncbi request reprint Images in pathology. Invasive squamous cell carcinoma of vulva that wanted to be a puppy
    Khush Mittal
    Surgical and Ob Gyn Pathology, Bellevue Hospital, New York, NY 10016, USA
    Int J Surg Pathol 14:335. 2006
  8. ncbi request reprint Precursor lesions for uterine leiomyosarcoma
    Khush Mittal
    Hum Pathol 38:1289. 2007
  9. ncbi request reprint Endometrial hyperplasia and carcinoma in endometrial polyps: clinicopathologic and follow-up findings
    Khush Mittal
    Department of Pathology, New York University School of Medicine, New York, NY, USA
    Int J Gynecol Pathol 27:45-8. 2008
    ..The above findings reinforce the need for hysterectomy especially in postmenopausal women with atypical complex hyperplasia or carcinoma in endometrial polyps even if these changes appear confined to the polyp in initial sampling...
  10. doi request reprint Antiproliferative effects by Let-7 repression of high-mobility group A2 in uterine leiomyoma
    Yi Peng
    Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
    Mol Cancer Res 6:663-73. 2008
    ..Our findings suggest that the Let-7-mediated repression of HMGA2 mechanism can be an important molecular event in leiomyoma growth...
  11. ncbi request reprint Ethnic differences in expression of the dysregulated proteins in uterine leiomyomata
    Jian Jun Wei
    Department of Pathology, New York University School of Medicine, Bellevue Hospital, 560 First Avenue, New York, NY 10016, USA
    Hum Reprod 21:57-67. 2006
    ..Black ethnicity is one of the risk factors for uterine leiomyomata (ULM). Little is known about the ethnic differences in leiomyoma-associated gene products in women with uterine leiomyomata...
  12. ncbi request reprint Large cell variant of small cell carcinoma, hypercalcemic type, of primary peritoneal origin
    Dorota A Popiolek
    Department of Pathology, 4W35B, New York University School of Medicine, Belluvue Hospital, 462 First Avenue, New York, NY 10016, USA
    Gynecol Oncol 96:249-53. 2005
    ..All reported cases involved an ovary, and one with primary peritoneal origin has not been described. Also, convincing neuroendocrine granules have not been illustrated...
  13. ncbi request reprint MIB-1 expression in cervical Papanicolaou tests correlates with dysplasia in subsequent cervical biopsies
    Zhuowen Zeng
    Department of Cytopathology, Albert Einstein College of Medicine Montefiore Medical Center, Bronx, New York, USA
    Appl Immunohistochem Mol Morphol 10:15-9. 2002
    ..It is able to identify cervical disease overlooked by cytologic screening; therefore, it may serve as an adjunct and complimentary tool to cervical cytology...
  14. ncbi request reprint Comparison of morphologic and immunohistochemical features of cervical microglandular hyperplasia with low-grade mucinous adenocarcinoma of the endometrium
    Wansong Qiu
    Department of Pathalogy, New York University School of Medicine and Medical Center, New York, New York 10016, USA
    Int J Gynecol Pathol 22:261-5. 2003
    ....
  15. ncbi request reprint Incidental findings in uterine prolapse specimen: frequency and implications
    Hong Yin
    Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
    Int J Gynecol Pathol 23:26-8. 2004
    ..As long as all grossly visible lesions are sampled, two routine sections were found to be sufficient to identify all significant lesions...
  16. ncbi request reprint Stromal reaction is a feature of diffusely infiltrating endometrial adenocarcinoma
    Khush Mittal
    Int J Gynecol Pathol 23:91; author reply 91. 2004
  17. ncbi request reprint Distinction of low-grade squamous intraepithelial lesions from high-grade squamous intraepithelial lesions based on quantitative analysis of proliferative activity
    Dorota Popiolek
    Department of Pathology, New York University School of Medicine, New Bellevue Hospital, New York, NY 10016, USA
    Oncol Rep 11:687-91. 2004
    ..MI and ME (percentage) appear helpful in grading equivocal SIL cases...
  18. ncbi request reprint False-positive squamous cell carcinoma in cervical smears: cytologic-histologic correlation in 19 cases
    Pascale Hummel Levine
    Department of Pathology, New York University School of Medicine, New York, New York 10016 6497, USA
    Diagn Cytopathol 28:23-7. 2003
    ..Pleomorphic and/or keratinizing dysplasia involving endocervical glands may exhibit the cytologic features of squamous-cell carcinoma on cervical Pap smears...
  19. ncbi request reprint Endometrial adenocarcinoma in situ in complex atypical hyperplasia: correlation with findings in subsequent hysterectomy specimen
    Karyna C Ventura
    New York University School of Medicine, New York, NY 10016, USA
    Int J Surg Pathol 12:225-30. 2004
    ..Identification of AIS in CAH cases provides useful prognostic information...
  20. ncbi request reprint Expression profile of tuberin and some potential tumorigenic factors in 60 patients with uterine leiomyomata
    Jianjun Wei
    Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
    Mod Pathol 18:179-88. 2005
    ..One group is associated with an alteration of tuberin and glucocorticoid receptor. The other group is associated with upregulation of human mobility group gene A2 and steroid receptor cofactors...
  21. ncbi request reprint Rhabdoid epithelioid leiomyosarcoma of the uterine corpus: a case report and literature review
    Pascale Hummel Levine
    New York University School of Medicine and Kaplan Comprehensive Cancer Center, New York, New York 10016 6497, USA
    Int J Surg Pathol 10:231-6. 2002
    ..The recognition of a rhabdoid phenotype is of clinical importance since these tumors are prone to be aggressive...
  22. ncbi request reprint Significance of the cytologic diagnosis of endocervical glandular involvement in high-grade squamous intraepithelial lesions
    Pascale Hummel Levine
    Department of Pathology, New York University School of Medicine and Kaplan Comprehensive Cancer Center, New York, New York 10016, USA
    Diagn Cytopathol 26:217-21. 2002
    ..In our experience, the cytologic diagnosis of EGI on Pap smears did not identify a group of patients with increased frequency of EGI on subsequent cone biopsies...
  23. ncbi request reprint Pleomorphic liposarcoma of the uterus: case report and literature review
    Pascale Hummel Levine
    Department of Pathology, New York University Medical Center, New York, NY 10016, USA
    Int J Gynecol Pathol 22:407-11. 2003
    ..The tumor recurred 9 months postoperatively. Although a variety of uterine tumors have been associated with tamoxifen treatment, this appears to be the first example of tamoxifen-associated uterine liposarcoma...
  24. ncbi request reprint Malignant mixed mullerian tumor of the vagina: case report with review of the literature, immunohistochemical study, and evaluation for human papilloma virus
    Matjaz Sebenik
    North Broward Medical Center, Deerfield Beach, FL 33064, USA
    Hum Pathol 38:1282-8. 2007
    ..In situ hybridization detected high-risk human papillomavirus DNA in both the carcinoma and the sarcoma components...
  25. ncbi request reprint Differential expression of selected gene products in uterine leiomyomata and adenomyosis
    Mary Levy
    Department of Pathology, New York University School of Medicine, New York, New York 10016, USA
    Fertil Steril 88:220-3. 2007
    ..With appropriate internal controls, there were significant differences in gene expression between adenomyosis and leiomyomata...
  26. ncbi request reprint Transforming growth factor-beta, estrogen, and progesterone converge on the regulation of p27Kip1 in the normal and malignant endometrium
    Jon Lecanda
    Departments of Pathology and Medicine, NYU Cancer Institute, New York University School of Medicine, New York, NY 10016, USA
    Cancer Res 67:1007-18. 2007
    ..Thus, p27 may be a central target for growth regulation of normal endometrium and in the pathogenesis of ECA...
  27. ncbi request reprint A micro-RNA signature associated with race, tumor size, and target gene activity in human uterine leiomyomas
    Tongsheng Wang
    Center for Applied Genomics, Public Health Research Institute, Newark, NJ, USA
    Genes Chromosomes Cancer 46:336-47. 2007
    ..This article contains Supplementary material available at http://www.interscience.wiley.com/jpages/1045-2257/suppmat...
  28. pmc Differences in mitotic activity may explain observed differences in HIF-1alpha response in cancers and stroma
    Khush Mittal
    PLoS Med 3:e370. 2006
  29. ncbi request reprint Expression profile of the tumorigenic factors associated with tumor size and sex steroid hormone status in uterine leiomyomata
    Jian Jun Wei
    Department of Pathology, New York University School of Medicine, New York, New York, USA
    Fertil Steril 84:474-84. 2005
    ..To use tissue microarray in combination with dendrogram cluster analysis to characterize some potential tumorigenic factors in association with tumor size and sex steroid hormone status in uterine leiomyomata...
  30. ncbi request reprint Localization of the ABCG2 mitoxantrone resistance-associated protein in normal tissues
    Patricia A Fetsch
    Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Cancer Lett 235:84-92. 2006
    ..These data suggest a dual function for ABCG2 in some tissues: the excretion of toxins and xenobiotics including anti-cancer agents and a potential, as-yet undefined role in the secretion of endogenous substrates...
  31. ncbi request reprint Malignant mixed Mullerian tumor of the fimbriated end of the fallopian tube: origin as an intraepithelial carcinoma
    Jean Pierre Gagner
    Department of Pathology, Bellevue Hospital Center, New York University School of Medicine, 462 First Avenue, Room 4W35, New York, NY 10016, USA
    Gynecol Oncol 97:219-22. 2005
    ..A paucity of examples of malignant mixed Mullerian tumors (MMMT) of the fimbriated end of the fallopian tube has been reported...