Research Topics
| Carmen V Melendez-VasquezSummaryAffiliation: New York University Country: USA Publications
| Collaborators
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Detail Information
Publications
Rho kinase regulates schwann cell myelination and formation of associated axonal domainsCarmen V Melendez-Vasquez
Department of Cell Biology, Skirball Institute of Biomolecular Medicine, New York University School of Medicine, New York, New York 10016, USA
J Neurosci 24:3953-63. 2004..They also indicate that the molecular machinery that promotes the wrapping of the glial membrane sheath around the axon is distributed along the entire length of the internode...
Myosin II is a negative regulator of oligodendrocyte morphological differentiationHaibo Wang
Department of Biological Sciences, Hunter College, City University of New York, New York, New York 10065, USA
J Neurosci Res 90:1547-56. 2012..Taken together, our results demonstrate that Fyn kinase downregulates NMII activity, thus promoting oligodendrocyte morphological differentiation...
MLCK regulates Schwann cell cytoskeletal organization, differentiation and myelinationEllen M Leitman
Department of Biological Sciences, Hunter College, City University of New York, New York, NY 10065, USA
J Cell Sci 124:3784-96. 2011..Our data indicate that myosin II activity is differentially regulated at various stages during myelination and that in the absence of MLCK the processes of SC differentiation and compact myelin assembly are uncoupled...
Myosin II has distinct functions in PNS and CNS myelin sheath formationHaibo Wang
Department of Biological Sciences, Hunter College, City University of New York, New York, NY 10065, USA
J Cell Biol 182:1171-84. 2008..Our data indicate that the mechanisms regulating myelination in the peripheral and central nervous systems are distinct...
Interleukin-1beta induces a reactive astroglial phenotype via deactivation of the Rho GTPase-Rock axisGareth R John
Corinne Goldsmith Dickinson Center for Multiple Sclerosis, Department of Neurology, Mount Sinai School of Medicine, New York, New York 10029, USA
J Neurosci 24:2837-45. 2004....
Promoting myelin repair and return of function in multiple sclerosisJingya Zhang
Corinne Goldsmith Dickinson Center for MS, Mount Sinai School of Medicine, New York, NY 10029, USA
FEBS Lett 585:3813-20. 2011..Here, we review translational research targeting oligodendrocyte protection and myelin repair in models of autoimmune demyelination, and their potential relevance as therapies in MS...
