Dolores Malaspina

Summary

Affiliation: New York University School of Medicine
Country: USA

Publications

  1. ncbi request reprint Negative symptoms, past and present: a historical perspective and moving to DSM-5
    Dolores Malaspina
    Institute for Social and Psychiatric Initiatives InSPIRES, Department of Psychiatry, New York University School of Medicine, NY, USA Creedmoor Psychiatric Center, NY State Office of Mental Health, NY, USA Electronic address
    Eur Neuropsychopharmacol 24:710-24. 2014
  2. ncbi request reprint Schizoaffective Disorder in the DSM-5
    Dolores Malaspina
    Department of Psychiatry, New York University, New York, NY, USA Creedmoor Psychiatric Center, New York State Office of Mental Health, USA Electronic address
    Schizophr Res 150:21-5. 2013
  3. doi request reprint Olfaction and cognition in schizophrenia: sex matters
    Dolores Malaspina
    Institute for Social and Psychiatric Initiatives, New York University School of Medicine, 500 1st Ave, NBV 22N14, New York, NY 10016, USA
    J Neuropsychiatry Clin Neurosci 24:165-75. 2012
  4. pmc Olfactory processing, sex effects and heterogeneity in schizophrenia
    Dolores Malaspina
    New York University School of Medicine, Institute for Social and Psychiatric Initiatives, 500 1st Avenue, NBV 22N10, New York, NY 10016, USA
    Schizophr Res 135:144-51. 2012
  5. pmc Incidence of schizophrenia among second-generation immigrants in the jerusalem perinatal cohort
    Cheryl Corcoran
    New York State Psychiatric Institute, Unit 2, 1051 Riverside Drive, New York, NY 10032, USA
    Schizophr Bull 35:596-602. 2009
  6. pmc Sleep duration as a risk factor for diabetes incidence in a large U.S. sample
    James E Gangwisch
    Columbia University, College of Physicians and Surgeons, Department of Psychiatry, Division of Medical Genetics, 1051 Riverside Drive, Mailbox 2, New York, NY 10032, USA
    Sleep 30:1667-73. 2007
  7. pmc Sleep duration associated with mortality in elderly, but not middle-aged, adults in a large US sample
    James E Gangwisch
    Columbia University, College of Physicians and Surgeons, Department of Psychiatry, Division of Medical Genetics, New York, NY 10032, USA
    Sleep 31:1087-96. 2008
  8. pmc Temporal association of cannabis use with symptoms in individuals at clinical high risk for psychosis
    Cheryl M Corcoran
    Columbia University, Department of Psychiatry, New York, NY, United States
    Schizophr Res 106:286-93. 2008
  9. pmc Paternal age related schizophrenia (PARS): Latent subgroups detected by k-means clustering analysis
    Hyejoo Lee
    Department of Applied Mathematics and Statistics, Stony Brook University, Stony Brook, NY, USA
    Schizophr Res 128:143-9. 2011
  10. pmc Later paternal age and sex differences in schizophrenia symptoms
    Paul J Rosenfield
    Columbia University, College of Physicians and Surgeons, Department of Psychiatry, New York, NY 10019, USA
    Schizophr Res 116:191-5. 2010

Research Grants

  1. JERUSALEM PERINATAL COHORT SCHIZOPHRENIA STUDY
    Dolores Malaspina; Fiscal Year: 1999
  2. Jerusalem Perinatal Cohort Schizophrenia Study II
    Dolores Malaspina; Fiscal Year: 2010
  3. Jerusalem Perinatal Cohort Schizophrenia Study II
    Dolores Malaspina; Fiscal Year: 2009
  4. Olfactory and Social Function in Schizophrenia
    Dolores Malaspina; Fiscal Year: 2006
  5. Mentoring Translational Schizophrenia Researchers
    Dolores Malaspina; Fiscal Year: 2006
  6. JERUSALEM PERINATAL COHORT SCHIZOPHRENIA STUDY
    Dolores Malaspina; Fiscal Year: 2006
  7. Jerusalem Perinatal Cohort Schizophrenia Study II
    Dolores Malaspina; Fiscal Year: 2007
  8. Olfactory and Social Function in Schizophrenia
    Dolores Malaspina; Fiscal Year: 2007
  9. Olfactory and Social Function in Schizophrenia
    Dolores Malaspina; Fiscal Year: 2006
  10. Olfactory and Social Function in Schizophrenia
    Dolores Malaspina; Fiscal Year: 2005

Detail Information

Publications78

  1. ncbi request reprint Negative symptoms, past and present: a historical perspective and moving to DSM-5
    Dolores Malaspina
    Institute for Social and Psychiatric Initiatives InSPIRES, Department of Psychiatry, New York University School of Medicine, NY, USA Creedmoor Psychiatric Center, NY State Office of Mental Health, NY, USA Electronic address
    Eur Neuropsychopharmacol 24:710-24. 2014
    ..Finally, this paper includes descriptions of the negative symptom items from over a dozen different scales. ..
  2. ncbi request reprint Schizoaffective Disorder in the DSM-5
    Dolores Malaspina
    Department of Psychiatry, New York University, New York, NY, USA Creedmoor Psychiatric Center, New York State Office of Mental Health, USA Electronic address
    Schizophr Res 150:21-5. 2013
    ....
  3. doi request reprint Olfaction and cognition in schizophrenia: sex matters
    Dolores Malaspina
    Institute for Social and Psychiatric Initiatives, New York University School of Medicine, 500 1st Ave, NBV 22N14, New York, NY 10016, USA
    J Neuropsychiatry Clin Neurosci 24:165-75. 2012
    ..These findings indicate significant sex differences in olfactory processing in schizophrenia. Combining the sexes in research analyses may obscure important differences...
  4. pmc Olfactory processing, sex effects and heterogeneity in schizophrenia
    Dolores Malaspina
    New York University School of Medicine, Institute for Social and Psychiatric Initiatives, 500 1st Avenue, NBV 22N10, New York, NY 10016, USA
    Schizophr Res 135:144-51. 2012
    ....
  5. pmc Incidence of schizophrenia among second-generation immigrants in the jerusalem perinatal cohort
    Cheryl Corcoran
    New York State Psychiatric Institute, Unit 2, 1051 Riverside Drive, New York, NY 10032, USA
    Schizophr Bull 35:596-602. 2009
    ..Few contemporary studies have evaluated the risk of schizophrenia among second-generation immigrants in other parts of the world...
  6. pmc Sleep duration as a risk factor for diabetes incidence in a large U.S. sample
    James E Gangwisch
    Columbia University, College of Physicians and Surgeons, Department of Psychiatry, Division of Medical Genetics, 1051 Riverside Drive, Mailbox 2, New York, NY 10032, USA
    Sleep 30:1667-73. 2007
    ..No plausible mechanism has been identified by which long sleep duration could lead to diabetes...
  7. pmc Sleep duration associated with mortality in elderly, but not middle-aged, adults in a large US sample
    James E Gangwisch
    Columbia University, College of Physicians and Surgeons, Department of Psychiatry, Division of Medical Genetics, New York, NY 10032, USA
    Sleep 31:1087-96. 2008
    ..No epidemiologic studies have published multivariate analyses stratified by age, even though life expectancy is 75 years and the majority of deaths occur in the elderly...
  8. pmc Temporal association of cannabis use with symptoms in individuals at clinical high risk for psychosis
    Cheryl M Corcoran
    Columbia University, Department of Psychiatry, New York, NY, United States
    Schizophr Res 106:286-93. 2008
    ..Cannabis use is reported to increase the risk for psychosis, but no prospective study has longitudinally examined drug use and symptoms concurrently in clinical high risk cases...
  9. pmc Paternal age related schizophrenia (PARS): Latent subgroups detected by k-means clustering analysis
    Hyejoo Lee
    Department of Applied Mathematics and Statistics, Stony Brook University, Stony Brook, NY, USA
    Schizophr Res 128:143-9. 2011
    ..This study uses a k-means clustering analysis approach to generate hypotheses about differences between PARS and other cases of schizophrenia...
  10. pmc Later paternal age and sex differences in schizophrenia symptoms
    Paul J Rosenfield
    Columbia University, College of Physicians and Surgeons, Department of Psychiatry, New York, NY 10019, USA
    Schizophr Res 116:191-5. 2010
    ..This study examined if PARS exhibits the symptom profile and sex differences that are consistently observed for schizophrenia in general, wherein males have an earlier onset age and more severe negative symptoms than females...
  11. pmc Earlier parental set bedtimes as a protective factor against depression and suicidal ideation
    James E Gangwisch
    Columbia University, College of Physicians and Surgeons, Department of Psychiatry, New York, NY 10032, USA
    Sleep 33:97-106. 2010
    ..Depression in an adolescent can affect his/her chosen bedtime, but it is less likely to affect a parent's chosen set bedtime which can establish a relatively stable upper limit that can directly affect sleep duration...
  12. pmc Effect of socioeconomic status and parents' education at birth on risk of schizophrenia in offspring
    Cheryl Corcoran
    Dept of Psychiatry, New York State Psychiatric Institute, Columbia University, 1051 Riverside Drive, Unit 2, New York, NY 10032, USA
    Soc Psychiatry Psychiatr Epidemiol 44:265-71. 2009
    ..Instead, a modest increase in risk for schizophrenia was observed only for those born at the bottom of the social ladder...
  13. doi request reprint Prenatal stress and affective disorders in a population birth cohort
    Karine Kleinhaus
    Departments of Psychiatry, New York University School of Medicine, New York, NY, USA
    Bipolar Disord 15:92-9. 2013
    ..We examined the relationship of the timing of an acute psychosocial threat during pregnancy to the incidence of affective disorders in offspring using data from a large birth cohort...
  14. ncbi request reprint The reliability and clinical correlates of figure-ground perception in schizophrenia
    Dolores Malaspina
    New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
    J Neuropsychiatry Clin Neurosci 16:277-83. 2004
    ....
  15. pmc Catatonic schizophrenia: a cohort prospective study
    Karine Kleinhaus
    Department of Psychiatry, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    Schizophr Bull 38:331-7. 2012
    ..This study is the first to describe catatonia using prospectively collected data and to examine how catatonic schizophrenia differs from, or resembles, other types of schizophrenia...
  16. pmc Olfactory acuity is associated with mood and function in a pilot study of stable bipolar disorder patients
    Caitlin Hardy
    Department of Psychiatry, New York University NYU School of Medicine, New York, NY, USA
    Bipolar Disord 14:109-17. 2012
    ..Olfactory dysfunction is described in several neuropsychiatric disorders but there is little research on olfactory processing in bipolar disorder...
  17. pmc Theory of Mind in patients at clinical high risk for psychosis
    Arielle D Stanford
    Division of Brain Stimulation and Therapeutic Modulation, New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
    Schizophr Res 131:11-7. 2011
    ..As capacity for ToM normally advances with brain maturation, research on ToM in individuals at heightened clinical risk for psychosis may reveal developmental differences independent of disease based differences...
  18. pmc Short sleep duration as a risk factor for hypercholesterolemia: analyses of the National Longitudinal Study of Adolescent Health
    James E Gangwisch
    Columbia University, College of Physicians and Surgeons, Department of Psychiatry, Division of Cognitive Neuroscience, 1051 Riverside Drive, Unit 74, New York, NY 10032, USA
    Sleep 33:956-61. 2010
    ..No previous published population studies have examined the longitudinal relationship between sleep duration and high cholesterol...
  19. pmc The factorial structure of the schedule for the deficit syndrome in schizophrenia
    David Kimhy
    Department of Psychiatry, Box 2, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    Schizophr Bull 32:274-8. 2006
    ..The mean severity of symptoms was 2.25 (S.D. = 1.06). We discuss possible links between the obtained factors and putative neurobiological mechanisms, as well as directions for future research...
  20. ncbi request reprint Definition and description of schizophrenia in the DSM-5
    Rajiv Tandon
    Department of Psychiatry, University of Florida Medical School, Gainesville, FL, USA Electronic address
    Schizophr Res 150:3-10. 2013
    ....
  21. doi request reprint Insomnia and sleep duration as mediators of the relationship between depression and hypertension incidence
    James E Gangwisch
    Division of Cognitive Neuroscience, Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Am J Hypertens 23:62-9. 2010
    ..No previous published population studies have examined whether insomnia and sleep duration mediate the relationship between depression and hypertension incidence...
  22. pmc Trajectory to a first episode of psychosis: a qualitative research study with families
    Cheryl Corcoran
    Department of Psychiatry New York State Psychiatric Institute, Columbia University, New York, NY 10032, USA
    Early Interv Psychiatry 1:308-15. 2007
    ..Qualitative research methods can be used to begin to elucidate the temporal unfolding of symptoms leading to a first episode of psychosis, and its impact on families...
  23. pmc Maternal household crowding during pregnancy and the offspring's risk of schizophrenia
    David Kimhy
    Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Schizophr Res 86:23-9. 2006
    ..We tested the hypothesis that a similar link is present in humans...
  24. ncbi request reprint Etiological heterogeneity and intelligence test scores in patients with schizophrenia
    Rachel Wolitzky
    Department of Medical Genetics, New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
    J Clin Exp Neuropsychol 28:167-77. 2006
    ..Overall, the results suggest that sporadic patients have better perceptual-organizational skills and faster speed of processing...
  25. ncbi request reprint Structure of the psychotic disorders classification in DSM-5
    Stephan Heckers
    Department of Psychiatry, Vanderbilt University, Nashville, TN, USA Electronic address
    Schizophr Res 150:11-4. 2013
    ..The structure of psychosis as outlined in the DSM-5 may serve as a stepping-stone towards a more valid classification system, as we await new data to redefine psychotic disorders...
  26. ncbi request reprint Familiarity preference in schizophrenia is associated with ambivalent attitudes towards others
    Daniel Antonius
    University at Buffalo, State University of New York, Buffalo, NY, USA Erie County Forensic Mental Health Services, Buffalo, NY, USA New York University School of Medicine, New York, NY, USA Electronic address
    Schizophr Res 150:229-34. 2013
    ..In schizophrenia, little is known about the effect of familiarity preference on judgments and attitudes toward others...
  27. ncbi request reprint Catatonia in DSM-5
    Rajiv Tandon
    Department of Psychiatry, University of Florida Medical School, Gainesville, FL, USA
    Schizophr Res 150:26-30. 2013
    ..These changes should improve the consistent recognition of catatonia across the range of psychiatric disorders and facilitate its specific treatment...
  28. pmc Time-to-pregnancy and risk of schizophrenia
    Mark G A Opler
    InSPIRES Department of Psychiatry, New York University School of Medicine, New York, NY, United States
    Schizophr Res 118:76-80. 2010
    ..010). These findings suggest that factors associated with fecundability, either male or female, may contribute to the risk of schizophrenia...
  29. doi request reprint Older paternal age strongly increases the morbidity for schizophrenia in sisters of affected females
    Mary Perrin
    Department of Psychiatry, New York University School of Medicine, New York, New York, USA
    Am J Med Genet B Neuropsychiatr Genet 153:1329-35. 2010
    ..The authors speculate that the hypothesized paternally expressed genes on the X chromosome might play some role in these observations...
  30. pmc Tetrachloroethylene exposure and risk of schizophrenia: offspring of dry cleaners in a population birth cohort, preliminary findings
    Mary C Perrin
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, 10032, USA
    Schizophr Res 90:251-4. 2007
    ..We observed an increased incidence of schizophrenia in offspring of parents who were dry cleaners (RR=3.4, 95% CI, 1.3-9.2, p=0.01). Tetrachloroethylene exposure warrants further investigation as a risk factor for schizophrenia...
  31. ncbi request reprint Does unwantedness of pregnancy predict schizophrenia in the offspring? Findings from a prospective birth cohort study
    Daniel B Herman
    New York State Psychiatric Institute, New York, NY, USA
    Soc Psychiatry Psychiatr Epidemiol 41:605-10. 2006
    ..We sought to replicate (or refute) a previous report of an association between unwantedness of a pregnancy and the risk of schizophrenia in the offspring...
  32. ncbi request reprint Olfactory identification and WAIS-R performance in deficit and nondeficit schizophrenia
    Regine Anna Seckinger
    New York State Psychiatric Institute, Columbia University, New York, NY 10032, USA
    Schizophr Res 69:55-65. 2004
    ..If so, then the relationship of University of Pennsylvania Smell Identification Test (UPSIT) scores with other neurocognitive measures in DS patients may point to the neural substrate of the deficit syndrome...
  33. pmc Neuronal generator patterns of olfactory event-related brain potentials in schizophrenia
    Jürgen Kayser
    Division of Cognitive Neuroscience, New York State Psychiatric Institute, New York, New York 10032, USA
    Psychophysiology 47:1075-86. 2010
    ..N1 sink and P2 source were markedly reduced in patients for high intensity stimuli, providing further neurophysiological evidence of olfactory dysfunction in schizophrenia...
  34. pmc Olfactory deficits, cognition and negative symptoms in early onset psychosis
    Cheryl Corcoran
    New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
    Schizophr Res 80:283-93. 2005
    ..However, smell identification has not been examined in adolescents with early onset psychosis, wherein diagnosis is often obscure, and there are few prognostic predictors...
  35. pmc Childhood trauma and prodromal symptoms among individuals at clinical high risk for psychosis
    Judy L Thompson
    Columbia University, Department of Psychiatry, 1051 Riverside Drive, New York, NY 10032, USA
    Schizophr Res 108:176-81. 2009
    ..However, little is known about the prevalence of childhood trauma and its relationship to attenuated positive and other symptoms in individuals at heightened clinical risk for psychosis...
  36. pmc Resting neural activity distinguishes subgroups of schizophrenia patients
    Dolores Malaspina
    New York State Psychiatric Institute, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    Biol Psychiatry 56:931-7. 2004
    ..We previously demonstrated symptom and physiologic differences between familial and sporadic schizophrenia patients and hypothesized that the groups would show different resting regional cerebral blood flow (rCBF) patterns...
  37. pmc Avolition and expressive deficits capture negative symptom phenomenology: implications for DSM-5 and schizophrenia research
    Julie W Messinger
    Institute for Social and Psychiatric Initiatives InSPIRES, Department of Psychiatry, New York University School of Medicine, New York, NY 10016, USA
    Clin Psychol Rev 31:161-8. 2011
    ..We recommend that these two domains should be assessed as separate dimensions in the DSM-5 criteria...
  38. ncbi request reprint A brief smell identification test discriminates between deficit and non-deficit schizophrenia
    Nora Goudsmit
    New York State Psychiatric Institute and Columbia University Departments of Psychiatry and the College of Physicians and Surgeons, 1051 Riverside Drive, New York, NY 10032, USA
    Psychiatry Res 120:155-64. 2003
    ..The results of this study support the utility of the B-SIT for schizophrenia research and highlight the robustness of the relationship between SID and social dysfunction in schizophrenia...
  39. pmc Schizophrenia comorbid with panic disorder: evidence for distinct cognitive profiles
    Erica Kirsten Rapp
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
    Psychiatry Res 197:206-11. 2012
    ..These data offer further support for a definable panic-psychosis subtype and suggest new etiological pathways for future research...
  40. ncbi request reprint Paternal age and intelligence: implications for age-related genomic changes in male germ cells
    Dolores Malaspina
    New York State Psychiatric Institute and Columbia University, New York, NY 10032, USA
    Psychiatr Genet 15:117-25. 2005
    ..There are also substantial genetic influences on intelligence, so de novo genetic events in male germ cells, which accompany advancing paternal age, may plausibly influence offspring intelligence...
  41. pmc Emotion awareness and regulation in individuals with schizophrenia: Implications for social functioning
    David Kimhy
    Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Psychiatry Res 200:193-201. 2012
    ..The present study highlights the importance of emotion awareness and regulation in schizophrenia, pointing to their substantial influence on social functioning above and beyond the impact of neurocognitive functioning...
  42. ncbi request reprint Olfaction and social drive in schizophrenia
    Dolores Malaspina
    New York State Psychiatric Institute, Columbia University, New York, USA
    Arch Gen Psychiatry 60:578-84. 2003
    ..We examined whether SIDs in schizophrenia were related broadly to negative symptoms, as are a number of other neuropsychological measures, or whether they might show a more specific relationship with social drive...
  43. ncbi request reprint Trail making and olfaction in schizophrenia: implications for processing speed
    Nora Goudsmit
    Department of Medical Genetics, New York State Psychiatric Institute, New York, NY 10032, USA
    CNS Spectr 9:344-9, 356. 2004
    ..Previous research has established a relationship between smell identification deficits (SID) and particular aspects of cognitive function among patients with schizophrenia...
  44. ncbi request reprint A model of verbal memory impairments in schizophrenia: two systems and their associations with underlying cognitive processes and clinical symptoms
    Gildas Brébion
    Schizophrenia Research Unit, New York State Psychiatric Institute, New York, NY, USA
    Psychol Med 35:133-42. 2005
    ..The results have been reported in previous papers. In this paper we show how all these data could be integrated into a consistent pattern of associations...
  45. ncbi request reprint Advancing paternal age and autism
    Abraham Reichenberg
    Department of Psychiatry and Seaver Center for Autism Research, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    Arch Gen Psychiatry 63:1026-32. 2006
    ..Maternal and paternal ages are associated with neurodevelopmental disorders...
  46. pmc Stigma in families of individuals in early stages of psychotic illness: family stigma and early psychosis
    Celine Wong
    Department of Psychiatry, Columbia University, New York, New York, USA
    Early Interv Psychiatry 3:108-15. 2009
    ..These forms of stigma may present a barrier to help seeking. However, little is known about stigma in the early stages of evolving psychotic disorder...
  47. pmc Computerized experience sampling method (ESMc): assessing feasibility and validity among individuals with schizophrenia
    David Kimhy
    Department of Psychiatry, Unit 2, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    J Psychiatr Res 40:221-30. 2006
    ..The authors discuss the potential applications of combining ESMc with ambulatory physiological measures...
  48. pmc Concurrent measurement of "real-world" stress and arousal in individuals with psychosis: assessing the feasibility and validity of a novel methodology
    David Kimhy
    Department of Psychiatry, Box 55, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    Schizophr Bull 36:1131-9. 2010
    ..Our aim is to the test the feasibility and validity of a novel methodology designed to measure concurrent stress and arousal in individuals with psychosis during "real-world" daily functioning...
  49. ncbi request reprint Assessing the heterogeneity of aggressive behavior traits: exploratory and confirmatory analyses of the reactive and instrumental aggression Personality Assessment Inventory (PAI) scales
    Daniel Antonius
    New York University School of Medicine, New York, NY, USA
    Violence Vict 28:587-601. 2013
    ..Overall, the exploratory and confirmatory analyses supported the existence of two latent PAI factor structures, which delineate personality traits related to reactive and instrumental aggression...
  50. ncbi request reprint Racial and ethnic effects on psychotic psychiatric diagnostic changes from admission to discharge: a retrospective chart review
    Deidre M Anglin
    Department of Psychiatry, Columbia University, New York State Psychiatric Institute, New York 10032, USA
    J Clin Psychiatry 69:464-9. 2008
    ..We examined the frequency upon admission and at discharge and further explored the pattern of diagnostic changes that occurred by racial/ethnic group...
  51. pmc Paternal age and risk of schizophrenia in adult offspring
    Alan S Brown
    Department of Psychiatry, College of Physicians and Surgeons of Columbia University, USA
    Am J Psychiatry 159:1528-33. 2002
    ..The study examined the relation between paternal age at the time of birth and risk of schizophrenia in the adult offspring...
  52. pmc Sleep duration and risk for hypertension in women: results from the nurses' health study
    James E Gangwisch
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Am J Hypertens 26:903-11. 2013
    ..Acute sleep restriction has been shown to increase blood pressure and sympathetic nervous system activity...
  53. pmc Odor identification, eye tracking and deficit syndrome schizophrenia
    Dolores Malaspina
    New York State Psychiatric Institute, Columbia University Department of Psychiatry, 1051 Riverside Drive, New York, NY 10032, USA
    Biol Psychiatry 51:809-15. 2002
    ..Deficit syndrome (DS) schizophrenia patients have smooth pursuit eye movement (SPEM) dysfunction. We examined if they also had smell identification deficits, since social affiliation is related to olfaction in other mammals...
  54. pmc White matter integrity and lack of insight in schizophrenia and schizoaffective disorder
    Daniel Antonius
    Department of Psychiatry, New York University School of Medicine, New York, NY 10016, USA
    Schizophr Res 128:76-82. 2011
    ..Despite the importance of this issue, the neural correlates of insight deficits in schizophrenia remain poorly understood...
  55. pmc Differential targeting of the CA1 subfield of the hippocampal formation by schizophrenia and related psychotic disorders
    Scott A Schobel
    Department of Psychiatry, Columbia University, College of Physicians and Surgeons, New York, New York, USA
    Arch Gen Psychiatry 66:938-46. 2009
    ..Because schizophrenia and related disorders have a chronic time course and subtle histopathology, it is difficult to identify which brain regions are differentially targeted...
  56. pmc Comparable family burden in families of clinical high-risk and recent-onset psychosis patients
    Celine Wong
    Department of Psychiatry, Columbia University, New York, USA
    Early Interv Psychiatry 2:256-61. 2008
    ..In this exploratory study, we examined the extent of burden reported by families of patients during a putative prodromal period and in the after-math of psychosis onset...
  57. ncbi request reprint Suicide attempts in schizophrenia: the role of command auditory hallucinations for suicide
    Jill M Harkavy-Friedman
    New York State Psychiatric Institute, New York, N Y, USA
    J Clin Psychiatry 64:871-4. 2003
    ..We examined the relationship between CAHS and demographic and clinical variables. We also investigated the relationship between CAHS and suicide attempts...
  58. pmc Aberrant epigenetic regulation could explain the relationship of paternal age to schizophrenia
    Mary C Perrin
    Department of Psychiatry, School of Medicine, New York University, New York, NY, USA
    Schizophr Bull 33:1270-3. 2007
    ..This article will discuss parental imprinting on the autosomal and X chromosomes and the alterations in epigenetic regulation that may lead to such errors...
  59. pmc Delusions in individuals with schizophrenia: factor structure, clinical correlates, and putative neurobiology
    David Kimhy
    Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Psychopathology 38:338-44. 2005
    ..Our goal is to examine the factor structure of delusions in antipsychotic-free individuals with diagnoses of schizophrenia/schizoaffective disorder...
  60. doi request reprint Critical periods and the developmental origins of disease: an epigenetic perspective of schizophrenia
    Mary Perrin
    New York University School of Medicine, Social and Psychiatric Initiatives InSPIRES, New York, New York 10016, USA
    Ann N Y Acad Sci 1204:E8-13. 2010
    ..This introduction considers the possibility that epigenetic change that may occur as paternal age advances or during fetal adversity may be causally related to the susceptibility for schizophrenia...
  61. pmc In vivo 7 Tesla imaging of the dentate granule cell layer in schizophrenia
    Ivan I Kirov
    Department of Radiology, New York University School of Medicine, 660 First Avenue, New York, NY 10016, USA
    Schizophr Res 147:362-7. 2013
    ..We used ultra high field magnetic resonance imaging (MRI) to compare DGCL morphology of schizophrenic patients to matched controls...
  62. ncbi request reprint The stress cascade and schizophrenia: etiology and onset
    Cheryl Corcoran
    New York State Psychiatric Institute Columbia University, New York, NY 10032, USA
    Schizophr Bull 29:671-92. 2003
    ....
  63. pmc A qualitative research study of the evolution of symptoms in individuals identified as prodromal to psychosis
    Cheryl Corcoran
    New York State Psychiatric Institute Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    Psychiatr Q 74:313-32. 2003
    ..Although preliminary, these results suggest that a trajectory of change in personality, relationships, and behavior from an essentially normal baseline may be consistent with increased risk for psychosis among prodromal adolescents...
  64. pmc Self-reported coping strategies in families of patients in early stages of psychotic disorder: an exploratory study
    Ruth Gerson
    Department of Psychiatry, New York University, New York, New York, USA
    Early Interv Psychiatry 5:76-80. 2011
    ..g. reinterpretation) and potentially maladaptive 'avoidant' strategies (denial/disengagement, use of alcohol and drugs). Little is known about coping strategies used by families of individuals with incipient or emergent psychosis...
  65. pmc Effects of excessive glucocorticoid receptor stimulation during early gestation on psychomotor and social behavior in the rat
    Karine Kleinhaus
    Department of Psychiatry New York University Medical Center, New York, NY, USA
    Dev Psychobiol 52:121-32. 2010
    ..Moreover, some of these deficits may be mediated by alterations in postnatal maternal behavior and physiology produced by early gestational exposure to excess glucocorticoids...
  66. pmc rTMS strategies for the study and treatment of schizophrenia: a review
    Arielle D Stanford
    Division of Brain Stimulation and Therapeutic Modulation, Department of Psychiatry, Columbia University New York State Psychiatric Institute, Cabrini Hospital, Mt Sinai Medical Center, New York, NY 10032, USA
    Int J Neuropsychopharmacol 11:563-76. 2008
    ..Consideration of these factors among others may broaden the scope of utility of TMS for schizophrenia as well as enhance its efficacy...
  67. pmc Paternal age and sporadic schizophrenia: evidence for de novo mutations
    Dolores Malaspina
    Columbia University Department of Psychiatry New York State Psychiatric Institute, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    Am J Med Genet 114:299-303. 2002
    ..7 years) than familial patients; so later childbirth was not attributable to parental psychiatric illness. These findings support the hypothesis that de novo mutations contribute to the risk for sporadic schizophrenia...
  68. pmc Multivoxel proton MR spectroscopy used to distinguish anterior cingulate metabolic abnormalities in patients with schizophrenia
    Caitlin J Hardy
    Department of Radiology, New York University School of Medicine, 660 First Ave, 4th Floor, New York, NY 10016, USA
    Radiology 261:542-50. 2011
    ..To test the hypothesis that anterior cingulate cortex (ACC) subregions in patients with schizophrenia are metabolically different from those in healthy control subjects...
  69. pmc High-frequency prefrontal repetitive transcranial magnetic stimulation for the negative symptoms of schizophrenia: a case series
    Arielle D Stanford
    Division of Brain Stimulation and Therapeutic Modulation, New York State Psychiatric Institute, New York, NY, USA
    J ECT 27:11-7. 2011
    ..This pilot study assessed higher doses of rTMS and assessed particular demographic factors that may influence treatment response...
  70. pmc Human hippocampal subfields in young adults at 7.0 T: feasibility of imaging
    Vasthie Prudent
    Departments of Radiology and Psychiatry, New York University School of Medicine, 660 First Ave, 4th Floor, New York, NY 10016, USA
    Radiology 254:900-6. 2010
    ..This imaging technique might be used to detect cellular disarray and degenerative changes in this sensitive circuit earlier than at 1.5 T or even 3.0 T. (c) RSNA, 2010...
  71. doi request reprint Psychiatric assessment of aggressive patients: a violent attack on a resident
    Daniel Antonius
    New York University School of Medicine, New York, NY 10016, USA
    Am J Psychiatry 167:253-9. 2010
    ..This report illustrates common deficiencies in the prevention of violence on inpatient psychiatric units and in the reporting and response to an assault, and has implications for residency and clinician training...
  72. ncbi request reprint Ethnicity effects on clinical diagnoses compared to best-estimate research diagnoses in patients with psychosis: a retrospective medical chart review
    Deidre M Anglin
    Department of Psychiatry, Columbia University, New York State Psychiatric Institute, New York, NY, USA
    J Clin Psychiatry 69:941-5. 2008
    ..Ethnicity effects on diagnoses are frequently reported and have variably been attributed to diagnostic biases versus ethnic differences in environmental exposures, and other factors...
  73. ncbi request reprint Schizophrenia: a neurodevelopmental or a neurodegenerative disorder
    Dolores Malaspina
    Department of Psychiatry and New York State Psychiatric Institute, Columbia University, New York, USA
    J Clin Psychiatry 67:e07. 2006
    ....
  74. pmc Revisiting the backward masking deficit in schizophrenia: individual differences in performance and modeling with transcranial magnetic stimulation
    Bruce Luber
    Brain Stimulation and Therapeutic Modulation Division, New York State Psychiatric Institute, New York, New York 10032, USA
    Biol Psychiatry 62:793-9. 2007
    ..In addition, increased knowledge of the visual system has opened the door for new techniques such as transcranial magnetic stimulation (TMS) to explore these deficits physiologically...
  75. ncbi request reprint Paternal age and preeclampsia
    Susan Harlap
    Department of Obstetrics and Gynecology and Kaplan Cancer Center, New York University School of Medicine, New York, NY 10016, USA
    Epidemiology 13:660-7. 2002
    ..Paternal aging is associated with premeiotic damage to spermatogonia, a mechanism by which new point mutations are introduced into the gene pool. We hypothesized that paternal age might contribute to preeclampsia...
  76. ncbi request reprint Preventing clinical deterioration in the course of schizophrenia: the potential for neuroprotection
    Jeffrey A Lieberman
    Columbia University College of Physicians and Surgeons and New York State Psychiatric Institute, New York, USA
    J Clin Psychiatry 67:983-90. 2006
  77. doi request reprint Developing patient-centered treatment protocols in brain stimulation: a rationale for combining quantitative and qualitative approaches in persons with HIV
    Mary Rosedale
    New York University College of Nursing, 246 Greene St, NY 10003, USA
    J Am Psychiatr Nurses Assoc 18:166-74. 2012
    ..The authors conclude that the complexity of studying novel treatments in complex and new patient populations requires complex research designs to capture the richness of data that inform translational research...
  78. doi request reprint Behavioral validation of avolition in schizophrenia
    Fabien Tremeau
    Nathan S Kline Institute for Psychiatric Research, Orangeburg, NY, United States
    Schizophr Res 138:255-61. 2012
    ..However, the concurrent validity of commonly-used avolition measures has not been studied, and direct observation may offer a more objective way to measure avolition...

Research Grants19

  1. JERUSALEM PERINATAL COHORT SCHIZOPHRENIA STUDY
    Dolores Malaspina; Fiscal Year: 1999
    ..We will lay the groundwork to add military induction neuropsychological data on these subjects and establish the feasibility of future brain imaging studies. ..
  2. Jerusalem Perinatal Cohort Schizophrenia Study II
    Dolores Malaspina; Fiscal Year: 2010
    ..This project may establish paternal age related SCZ as a separate and common variant, explaining a quarter or more of cases, with known genetic causes, setting the stage for specific interventions. ..
  3. Jerusalem Perinatal Cohort Schizophrenia Study II
    Dolores Malaspina; Fiscal Year: 2009
    ..This project may establish paternal age related SCZ as a separate and common variant, explaining a quarter or more of cases, with known genetic causes, setting the stage for specific interventions. ..
  4. Olfactory and Social Function in Schizophrenia
    Dolores Malaspina; Fiscal Year: 2006
    ..Not all schizophrenia patients have olfactory dysfunction or social deficits and we also expect to discern homogeneous subgroups within the broader diagnosis of schizophrenia. ..
  5. Mentoring Translational Schizophrenia Researchers
    Dolores Malaspina; Fiscal Year: 2006
    ....
  6. JERUSALEM PERINATAL COHORT SCHIZOPHRENIA STUDY
    Dolores Malaspina; Fiscal Year: 2006
    ..We will lay the groundwork to add military induction neuropsychological data on these subjects and establish the feasibility of future brain imaging studies. ..
  7. Jerusalem Perinatal Cohort Schizophrenia Study II
    Dolores Malaspina; Fiscal Year: 2007
    ..This project may establish paternal age related SCZ as a separate and common variant, explaining a quarter or more of cases, with known genetic causes, setting the stage for specific interventions. ..
  8. Olfactory and Social Function in Schizophrenia
    Dolores Malaspina; Fiscal Year: 2007
    ..Not all schizophrenia patients have olfactory dysfunction or social deficits and we also expect to discern homogeneous subgroups within the broader diagnosis of schizophrenia. ..
  9. Olfactory and Social Function in Schizophrenia
    Dolores Malaspina; Fiscal Year: 2006
    ..Not all schizophrenia patients have olfactory dysfunction or social deficits and we also expect to discern homogeneous subgroups within the broader diagnosis of schizophrenia. ..
  10. Olfactory and Social Function in Schizophrenia
    Dolores Malaspina; Fiscal Year: 2005
    ..Not all schizophrenia patients have olfactory dysfunction or social deficits and we also expect to discern homogeneous subgroups within the broader diagnosis of schizophrenia. ..
  11. Olfactory and Social Function in Schizophrenia
    Dolores Malaspina; Fiscal Year: 2004
    ..Not all schizophrenia patients have olfactory dysfunction or social deficits and we also expect to discern homogeneous subgroups within the broader diagnosis of schizophrenia. ..
  12. JERUSALEM PERINATAL COHORT SCHIZOPHRENIA STUDY
    Dolores Malaspina; Fiscal Year: 2003
    ..We will lay the groundwork to add military induction neuropsychological data on these subjects and establish the feasibility of future brain imaging studies. ..
  13. JERUSALEM PERINATAL COHORT SCHIZOPHRENIA STUDY
    Dolores Malaspina; Fiscal Year: 2002
    ..We will lay the groundwork to add military induction neuropsychological data on these subjects and establish the feasibility of future brain imaging studies. ..
  14. JERUSALEM PERINATAL COHORT SCHIZOPHRENIA STUDY
    Dolores Malaspina; Fiscal Year: 2001
    ..We will lay the groundwork to add military induction neuropsychological data on these subjects and establish the feasibility of future brain imaging studies. ..
  15. JERUSALEM PERINATAL COHORT SCHIZOPHRENIA STUDY
    Dolores Malaspina; Fiscal Year: 2001
    ..We will lay the groundwork to add military induction neuropsychological data on these subjects and establish the feasibility of future brain imaging studies. ..
  16. JERUSALEM PERINATAL COHORT SCHIZOPHRENIA STUDY
    Dolores Malaspina; Fiscal Year: 2000
    ..We will lay the groundwork to add military induction neuropsychological data on these subjects and establish the feasibility of future brain imaging studies. ..
  17. Jerusalem Perinatal Cohort Schizophrenia Study II
    Dolores Malaspina; Fiscal Year: 2010
    ..This project may establish paternal age related SCZ as a separate and common variant, explaining a quarter or more of cases, with known genetic causes, setting the stage for specific interventions. ..