Research Topics
| David LivingstonSummaryAffiliation: New Jersey Country: USA Publications
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Publications
Obesity does not increase morbidity and mortality after laparotomy for traumaDavid H Livingston
New Jersey Trauma Center, Division of Trauma, Department of Surgery, New Jersey Medical School, Newark, New Jersey, USA
Am Surg 79:247-52. 2013..Although obese trauma patients do have increased infectious morbidity, wound dehiscence, and a prolonged length of stay, increased BMI is not an independent predictor of increased morbidity or mortality after trauma laparotomy...
Annual pediatric pedestrian education does not improve pedestrian behaviorDavid H Livingston
Department of Surgery, Division of Trauma, UMDNJ New Jersey Medical School, Newark, New Jersey, USA
J Trauma 71:1120-4; discussion 1124-5. 2011..We examined whether this program could create similar long-term cognitive and behavioral changes in our school-aged children...- A fate worse than death? Long-term outcome of trauma patients admitted to the surgical intensive care unitDavid H Livingston
Division of Trauma, Department of Surgery, UMDNJ New Jersey Medical School, Newark, New Jersey 07103 2406, USA
J Trauma 67:341-8; discussion 348-9. 2009..the reintegration of patients into the society to lead an active and a productive life is the ultimate goal of trauma center care, we questioned whether our "success" may condemn these patients to a fate worse than death?.. - CT diagnosis of Rib fractures and the prediction of acute respiratory failureDavid H Livingston
Division of Trauma, Department of Surgery, New Jersey Medical School, Newark, New Jersey, USA
J Trauma 64:905-11. 2008.... 
Bone marrow failure following severe injury in humansDavid H Livingston
Departments of Surgery, University Hospital E 245, 150 Bergen Street, Newark, NJ 07103, USA
Ann Surg 238:748-53. 2003....- Emergency department discharge of patients with a negative cranial computed tomography scan after minimal head injuryD H Livingston
Department of Surgery, Preventive Medicine and Community Health, New Jersey Medical School, Newark, New Jersey, USA
Ann Surg 232:126-32. 2000.... - Free fluid on abdominal computed tomography without solid organ injury after blunt abdominal injury does not mandate celiotomyD H Livingston
Department of Surgery, New Jersey Medical School, University Hospital E 245, 150 Bergen St, Newark, NJ 07103, USA
Am J Surg 182:6-9. 2001..This study examined the rate of intestinal injury in patients with free fluid on abdominal CT after blunt abdominal trauma... - Civilian craniocerebral gunshot wounds: an update in predicting outcomesTiffany Murano
Department of Surgery, Division of Emergency Medicine, UMDNJ-New Jersey Medical School, Newark, New Jersey 07103, USA
Am Surg 71:1009-14. 2005..This is not only important in determining treatment algorithms for physicians but also for appropriate counseling of family members to educate them with regard to patients' outcomes... - A prospective evaluation of the value of repeat cranial computed tomography in patients with minimal head injury and an intracranial bleedZiad C Sifri
Department of Surgery, New Jersey Medical School, Newark, NJ, USA
J Trauma 61:862-7. 2006..The goal of this study was to prospectively assess the value of a repeat cranial CT in patients with a MHI and an ICB who have a normal neurologic examination... - Spinal injuries in pedestrians struck by motor vehiclesMichael J Vives
Department of Orthopaedics, University of Medicine and Dentistry New Jersey Medical School, Newark, NJ, USA
J Spinal Disord Tech 21:281-7. 2008..Retrospective study of consecutive patients that were struck by motor vehicles and sustained spinal injuries over a 6-year period from 1997 to 2003... - Sex hormones affect bone marrow dysfunction after trauma and hemorrhagic shockZiad C Sifri
Division of Trauma, Department of Surgery, New Jersey Medical School, Newark, NJ, USA
Crit Care Med 35:864-9. 2007..Therefore, the present study examines the effects of sex hormones on post-T/HS BM dysfunction by measuring clonogenic growth of BM progenitors in castrated male rats and in ovariectomized and proestrus female rats... - Recovery at one year following isolated traumatic brain injury: a Western Trauma Association prospective multicenter trialDavid H Livingston
Department of Surgery, New Jersey Trauma Center, UMDNJ-New Jersey Medical School, Newark, New Jersey, USA
J Trauma 59:1298-304; discussion 1304. 2005..Age is an exceedingly important parameter affecting recovery from isolated TBI... - Value of repeat cranial computed axial tomography scanning in patients with minimal head injuryZiad C Sifri
Division of Trauma, Department of Surgery, University of Medicine and Dentistry of New Jersey-New Jersey Medical School, University Hospital M-243, 150 Bergen St, Newark, NJ 07103, USA
Am J Surg 187:338-42. 2004..CONCLUSIONS: A persistently normal or improving neurological examination in a patient with MHI appears to exclude the need for neurosurgical intervention and thus a repeat cranial CAT scan... - Bone marrow failure in male rats following trauma/hemorrhagic shock (T/HS) is mediated by mesenteric lymph and modulated by castrationZiad C Sifri
Division of Trauma, Department of Surgery, New Jersey Medical School, Newark, NJ 07103, USA
Shock 25:12-6. 2006..Further studies are needed to elucidate potential therapeutic effects of lymph manipulation in hematopoiesis after injury... - Hematopoietic progenitor cells mobilize to the site of injury after trauma and hemorrhagic shock in ratsChirag D Badami
Department of Surgery, New Jersey Medical School, Newark, NJ, USA
J Trauma 63:596-600; discussion 600-2. 2007..We investigated the hypothesis that HPC will specifically migrate to sites of tissue trauma and that this process is exacerbated by hemorrhagic shock (HS)... - Resistance of the female, as opposed to the male, intestine to I/R-mediated injury is associated with increased resistance to gut-induced distant organ injuryEdwin A Deitch
Department of Surgery, New Jersey Medical School, UMDNJ, Newark, NJ 07103, USA
Shock 29:78-83. 2008..These results indicate that the resistance of proestrus female rats to gut injury and gut-induced distant organ injury is greater than that observed in male rats... - Changing the culture around end-of-life care in the trauma intensive care unitAnne C Mosenthal
Division of Trauma Critical Care, Department of Surgery, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, USA
J Trauma 64:1587-93. 2008..Patients are young, prognosis uncertain, and conflict common around goals of care. We hypothesized that early, structured communication in the trauma ICU would improve end-of-life care practice... - The impact of obesity on the outcome of emergency intubation in trauma patientsZiad C Sifri
Department of Surgery, New Jersey Trauma Center, UMDNJ New Jersey Medical School, Newark, New Jersey, USA
J Trauma 65:396-400. 2008..We therefore hypothesize that obese trauma patients requiring emergency intubation are at increased risk for unsuccessful intubation and airway-related complications... - Hormonally active women tolerate shock-trauma better than do men: a prospective study of over 4000 trauma patientsEdwin A Deitch
Department of Surgery, New Jersey Medical School, Newark, New Jersey 07103, USA
Ann Surg 246:447-53; discussion 453-5. 2007..To test the hypothesis that comparably injured women, especially those in the hormonally active age groups, would manifest a better preserved hemodynamic response and tissue perfusion after major trauma than do men... - Gender differences in glucose variability after severe traumaAlicia M Mohr
Department of Surgery, UMDNJ New Jersey Medical School, Newark, New Jersey 07103, USA
Am Surg 76:896-902. 2010..In females, mortality cannot be predicted based on BG levels or BG variability. These data have significant implications for gender-related differences in postinjury management... - Isolated thoracolumbar transverse process fractures: call physical therapy, not spineAdena Homnick
Department of Surgery, Division of Trauma, UMDNJ New Jersey Medical School, Newark, New Jersey, USA
J Trauma 63:1292-5. 2007..Yet, where no associated spine injuries are found initially, such isolated TVPFx appear to be benign... - Sexual dimorphism in the activation of neutrophils by shock mesenteric lymphJohn M Adams
Department of Surgery, Division of Trauma, UMDNJ-New Jersey Medical School, Newark, New Jersey 07103, USA
Surg Infect (Larchmt) 4:37-44. 2003..The decrease in pathologic PMN activation seen after T/HS in proestrous female rats depends on soluble mediators present in plasma. The decreased PMN RB seen after T/HS in proestrous females is mediated by calcium-independent pathways... - Angiographic embolization for liver injuries: low mortality, high morbidityAlicia M Mohr
Department of Surgery, University of Medicine and Dentistry of New Jersey New Jersey Medcial School, Newark, 07103, USA
J Trauma 55:1077-81; discussion 1081-2. 2003..This study examines further the role of AE in both blunt and penetrating liver injuries and the outcomes of its use... - Isolated traumatic brain injury: age is an independent predictor of mortality and early outcomeAnne C Mosenthal
Department of Surgery, New Jersey Medical School, Newark, New Jersey 07103, USA
J Trauma 52:907-11. 2002..The purpose of this study was to investigate the role of age in the mortality and early outcome from isolated TBI... - The effect of age on functional outcome in mild traumatic brain injury: 6-month report of a prospective multicenter trialAnne C Mosenthal
Department of Surgery, New Jersey Trauma Center, University of Medicine and Dentistry of New Jersey New Jersey, Medical School, Newark, New Jersey, USA
J Trauma 56:1042-8. 2004..We hypothesized that surviving elderly patients would also have decreased functional outcome, and this study examined the functional outcome of patients with isolated TBI at discharge and at 6 months posthospitalization... - The role of lymph factors in lung injury, bone marrow suppression, and endothelial cell dysfunction in a primate model of trauma-hemorrhagic shockEdwin A Deitch
Department of Surgery, UMDNJ New Jersey Medical School, Newark, New Jersey 07103, USA
Shock 22:221-8. 2004..Thus, in a primate model of T/HS, gut-derived factors carried in the lymph potentiates lung injury and endothelial dysfunction, and suppresses bone marrow progenitor cell growth... - Use of aerosolized aminoglycosides in the treatment of Gram-negative ventilator-associated pneumoniaAlicia M Mohr
Division of Trauma Critical Care, Department of Surgery, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, New Jersey 07103, USA
Surg Infect (Larchmt) 8:349-57. 2007..This study examined the role of aerosolized aminoglycosides in the treatment of VAP in surgical ICU patients... - Management of trauma to the male external genitalia: the usefulness of American Association for the Surgery of Trauma organ injury scalesAlicia M Mohr
Department of Surgery, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark 07103, USA
J Urol 170:2311-5. 2003..To assist in defining the indications for nonoperative management the usefulness of the American Association for the Surgery of Trauma (AAST) organ injury scales for these injuries was examined... - Recurrent penetrating spinal cord injuryCarl J Hauser
Department of Surgery, UMDNJ-New Jersey Medical School, Newark, New Jersey 07103, USA
J Trauma 53:167. 2002 - Prospective validation of computed tomographic screening of the thoracolumbar spine in traumaCarl J Hauser
Department of Surgery, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, 07103, USA
J Trauma 55:228-34; discussion 234-5. 2003..We sought to evaluate whether helical truncal CT scanning performed to evaluate visceral trauma images the spine as well as dedicated XR/TLS... - Autopsies in trauma do not add to peer review or quality assuranceRaquel M Forsythe
Department of Surgery, New Jersey Medical School, Newark, New Jersey, USA
J Trauma 53:321-5. 2002..This was true even in cases where the final QA determination was held pending the results of the autopsy. Autopsy rates may not be a useful parameter in evaluating a trauma QA program... - Prospective study of neutrophil chemokine responses in trauma patients at risk for pneumoniaMichael H Tarlowe
Division of Trauma, UMD/New Jersey Medical School, Department of Surgery, MSB G-592, 185 South Orange Avenue, Newark, NJ 07103, USA
Am J Respir Crit Care Med 171:753-9. 2005..Suppression of high-affinity PMN receptors, like CXCR2, may predispose to pneumonia after trauma or other inflammatory conditions that lead to systemic inflammatory response syndrome... - Mobilization of bone marrow cells to the site of injury is necessary for wound healingSalil Shah
Division of Trauma, Department of Surgery, UMDNJ New Jersey Medical School, Newark, New Jersey, USA
J Trauma 67:315-21; discussion 321-2. 2009..Postinjury mesenteric lymph has been shown to cause early organ failure. Thus, we hypothesized that diversion of mesenteric lymph would improve early organ dysfunction through decreased mobilization of BM HPC to the lung... - Effect of an educational video on emergency department patient stroke knowledgeYu Feng Chan
Department of Surgery, Division of Emergency Medicine, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, USA
J Emerg Med 34:215-20. 2008..A stroke educational videotape improves the knowledge of this dangerous disease and may be a valuable and relatively low-cost tool for focused patient education in the Emergency Department waiting room... - Small volume albumin administration protects against hemorrhagic shock-induced bone marrow dysfunctionAdena J Osband
Division of Trauma, Department of Surgery, New Jersey Medical School, Newark, New Jersey 07103, USA
J Trauma 56:279-83. 2004..05). CONCLUSIONS: Small doses of albumin fully restore CFU-GM and BFU-E to sham values. We postulate that the binding of circulating toxic factors by albumin may play a role in this prevention of T/HS-induced BM suppression... - Attenuation of shock-induced acute lung injury by sphingosine kinase inhibitionCindy Lee
Department of Surgery, Division of Trauma, University of Medicine and Dentistry of New Jersey Medical School, Newark, New Jersey, USA
J Trauma 57:955-60. 2004..SK inhibition therefore appears to be an important novel candidate therapy for inflammatory organ injury after shock... - Store-operated calcium channel inhibition attenuates neutrophil function and postshock acute lung injuryCindy Lee
Department of Surgery, Division of Trauma, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, NJ 07103, USA
J Trauma 59:56-63; discussion 63. 2005..The relative specificity of SOCE channel blockade for "nonexcitable" cells such as PMNs may make it a valuable form of chemoprophylaxis for the inflammatory consequences of hemorrhagic shock in trauma patients... - Trauma from tire and rim explosions: A retrospective analysisRobert S Sheperd
University of Medicine and Dentistry of New Jersey, New Jersey Dental School, Newark, NJ, USA
J Oral Maxillofac Surg 62:36-8. 2004..Reductions in injuries have been seen since the implementation of physical safety measures by the Occupational Safety and Health Administration and the National Highway Transportation Safety Board... - Intrapancreatic bile duct injury: case reportSanjeev Kaul
Department of Surgery, Division of Trauma, University of Medicine and Dentistry of New Jersey, Newark, New Jersey, USA
J Trauma 52:786-8. 2002 - Hematopoietic progenitor cell mobilization is mediated through beta-2 and beta-3 receptors after injuryKeith A Beiermeister
Division of Trauma, Department of Surgery, UMDNJ New Jersey Medical School, Newark, New Jersey 07103, USA
J Trauma 69:338-43. 2010..Given the vast physiologic effects of nonselective BB, the aim of this study is to delineate the role of selective BB in HPC growth and mobilization... - Adrenergic modulation of erythropoiesis following severe injury is mediated through bone marrow stromaRodrigo B Fonseca
Department of Surgery, Division of Trauma, UMDNJ-New Jersey Medical School, Newark, NJ 07103, USA
Surg Infect (Larchmt) 5:385-93. 2004..Adrenergic agonists have a clear stimulatory effect on the growth of primitive erythroid precursors in normal BM. The adrenergic stimulus appears to be mediated via BM stroma... - Inflammatory chemoreceptor cross-talk suppresses leukotriene B4 receptor 1-mediated neutrophil calcium mobilization and chemotaxis after traumaMichael H Tarlowe
Department of Surgery, Division of Trauma, University of Medicine and Dentistry of New Jersey-New Jersey Medical School, Newark, NJ 07103, USA
J Immunol 171:2066-73. 2003..Diminished LT receptor activity due to cross-talk with CXC receptors can inhibit PMN recruitment to infective sites. This may predispose injured patients to septic complications... - Descending necrotizing mediastinitis: unique complication of central venous catheterizationFrancis J Caputo
Department of Surgery, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, New Jersey, USA
Surg Infect (Larchmt) 8:611-4. 2007..However, these devices are not without complications. We describe the first reported case of descending necrotizing mediastinitis secondary to central venous catheterization without evidence of associated vascular perforation... - Pregnancy is not a useful tissue expander in patients with an open abdomen: a case reportA Ylenia Giuffrida
Department of Surgery, Division of Trauma, University of Medicine and Dentistry of New Jersey Medical School, Newark, New Jersey 07103, USA
J Trauma 57:881-3. 2004 - Necrotizing fasciitis and sepsis caused by Aeromonas hydrophila after crush injury of the lower extremitySean F Monaghan
Section of Trauma and Critical Care, Department of Surgery, New Jersey Medical School, Newark, New Jersey, USA
Surg Infect (Larchmt) 9:459-67. 2008..There are sporadic reports of cases of sepsis or necrotizing fasciitis caused by A. hydrophila but no other cases of severe infection secondary to trauma. The mortality rate of septic shock caused by A. hydrophila approaches 100%... - Store-operated calcium entry in human neutrophils reflects multiple contributions from independently regulated pathwaysKiyoshi Itagaki
Department of Surgery, Division of Trauma, New Jersey Medical School, Newark, NJ 07103, USA
J Immunol 168:4063-9. 2002..They appear to reflect Ca(2+) transport through a variety of channels that are independently regulated to varying degrees by store depletion and by G protein-coupled receptor activation...
Research Grants
- TRAUMA-RELATED ERYTHROPOIETIC SUPPRESSIONDavid Livingston; Fiscal Year: 2003..Understanding the mechanisms behind post-trauma anemia will allow therapeutic interventions improving endogenous erythropoiesis to be targeted. ..