Soohee Lee

Summary

Affiliation: New York Blood Center
Country: USA

Publications

  1. ncbi request reprint Mutations that diminish expression of Kell surface protein and lead to the Kmod RBC phenotype
    Soohee Lee
    Lindsley F Kimball Research Institute, New York Blood Center, New York, New York 10021, USA
    Transfusion 43:1121-5. 2003
  2. ncbi request reprint Proteolytic processing of big endothelin-3 by the kell blood group protein
    S Lee
    The Lindsley F Kimball Research Institute of the New York Blood Center, New York, NY, USA
    Blood 94:1440-50. 1999
  3. ncbi request reprint Point mutations in KEL exon 8 determine a high-incidence (RAZ) and a low-incidence (KEL25, VLAN) antigen of the Kell blood group system
    S Lee
    Lindsley F Kimball Research Institute of the New York Blood Center, 310 East 67th Street, New York, NY 10021, USA
    Vox Sang 81:259-63. 2001
  4. ncbi request reprint Endothelin-3-converting enzyme activity of the KEL1 and KEL6 phenotypes of the Kell blood group system
    Quan Sha
    Lindsley F Kimball Research Institute of the New York Blood Center, 310 East 67th Street, New York, NY 10021, USA
    J Biol Chem 281:7180-2. 2006
  5. pmc Insights into extensive deletions around the XK locus associated with McLeod phenotype and characterization of two novel cases
    Jianbin Peng
    New York Blood Center, New York, NY 10021, USA
    Gene 392:142-50. 2007
  6. ncbi request reprint Point mutations causing the McLeod phenotype
    David C W Russo
    Lindsley F Kimball Research Institute, The New York Blood Center, New York, New York 10021, USA
    Transfusion 42:287-93. 2002
  7. ncbi request reprint Changes in red cell ion transport, reduced intratumoral neovascularization, and some mild motor function abnormalities accompany targeted disruption of the Mouse Kell gene (Kel)
    Xiang Zhu
    Department of Pathology, New York Blood Center, New York, New York, USA
    Am J Hematol 84:492-8. 2009
  8. ncbi request reprint Expression profiles of mouse Kell, XK, and XPLAC mRNA
    Soohee Lee
    The New York Blood Center, 310 East 67th Street, New York, NY 10021, USA
    J Histochem Cytochem 55:365-74. 2007
  9. ncbi request reprint Identification of two new members, XPLAC and XTES, of the XK family
    Giulia Calenda
    The Lindsley F Kimball Research Institute of the New York Blood Center, 310 East 67th Street, New York, NY 10021, USA
    Gene 370:6-16. 2006
  10. ncbi request reprint Molecular basis of two novel high-prevalence antigens in the Kell blood group system, KALT and KTIM
    Soohee Lee
    New York Blood Center, New York, New York 10021, USA
    Transfusion 46:1323-7. 2006

Collaborators

Detail Information

Publications19

  1. ncbi request reprint Mutations that diminish expression of Kell surface protein and lead to the Kmod RBC phenotype
    Soohee Lee
    Lindsley F Kimball Research Institute, New York Blood Center, New York, New York 10021, USA
    Transfusion 43:1121-5. 2003
    ..Kmod is an inherited rare RBC phenotype characterized by weak but detectable expression of high-incidence Kell antigens...
  2. ncbi request reprint Proteolytic processing of big endothelin-3 by the kell blood group protein
    S Lee
    The Lindsley F Kimball Research Institute of the New York Blood Center, New York, NY, USA
    Blood 94:1440-50. 1999
    ..These data demonstrate that the Kell blood group protein is a proteolytic enzyme that processes big ET-3, generating ET-3, a potent bioactive peptide with multiple biological roles...
  3. ncbi request reprint Point mutations in KEL exon 8 determine a high-incidence (RAZ) and a low-incidence (KEL25, VLAN) antigen of the Kell blood group system
    S Lee
    Lindsley F Kimball Research Institute of the New York Blood Center, 310 East 67th Street, New York, NY 10021, USA
    Vox Sang 81:259-63. 2001
    ..The molecular basis of two Kell blood group antigens, RAZ (provisionally KEL27) and VLAN (KEL25), were determined...
  4. ncbi request reprint Endothelin-3-converting enzyme activity of the KEL1 and KEL6 phenotypes of the Kell blood group system
    Quan Sha
    Lindsley F Kimball Research Institute of the New York Blood Center, 310 East 67th Street, New York, NY 10021, USA
    J Biol Chem 281:7180-2. 2006
    ....
  5. pmc Insights into extensive deletions around the XK locus associated with McLeod phenotype and characterization of two novel cases
    Jianbin Peng
    New York Blood Center, New York, NY 10021, USA
    Gene 392:142-50. 2007
    ..The non-synonymous to synonymous nucleotide substitution rate ratio (omega=dN/dS) in these genes was examined. CYBB and RPGR show evidence of positive selection, whereas DMD, XK and OTC are subject to selective constraint...
  6. ncbi request reprint Point mutations causing the McLeod phenotype
    David C W Russo
    Lindsley F Kimball Research Institute, The New York Blood Center, New York, New York 10021, USA
    Transfusion 42:287-93. 2002
    ..The McLeod phenotype may also be caused by mutations at a different splice site and by a novel mutation encoding an amino acid substitution that prevents transport to the cell surface...
  7. ncbi request reprint Changes in red cell ion transport, reduced intratumoral neovascularization, and some mild motor function abnormalities accompany targeted disruption of the Mouse Kell gene (Kel)
    Xiang Zhu
    Department of Pathology, New York Blood Center, New York, New York, USA
    Am J Hematol 84:492-8. 2009
    ..In this regard, the Kell knockout mouse provides a good animal model for the study of normal and/or pathophysiological functions of Kell glycoprotein...
  8. ncbi request reprint Expression profiles of mouse Kell, XK, and XPLAC mRNA
    Soohee Lee
    The New York Blood Center, 310 East 67th Street, New York, NY 10021, USA
    J Histochem Cytochem 55:365-74. 2007
    ..Coexpression of Kell and XK in erythroid tissues and the different expressions in non-erythroid tissues suggest that XK may have a complementary hematological function with Kell and a separate role in other tissues...
  9. ncbi request reprint Identification of two new members, XPLAC and XTES, of the XK family
    Giulia Calenda
    The Lindsley F Kimball Research Institute of the New York Blood Center, 310 East 67th Street, New York, NY 10021, USA
    Gene 370:6-16. 2006
    ..1. Phylogenetic analysis shows that there are at least 5 additional vertebrate genes that are evolutionarily distantly related to the XK family. A domain with consensus sequences (ced-8 domain) for the extended family is described...
  10. ncbi request reprint Molecular basis of two novel high-prevalence antigens in the Kell blood group system, KALT and KTIM
    Soohee Lee
    New York Blood Center, New York, New York 10021, USA
    Transfusion 46:1323-7. 2006
    ..Two probands were studied whose serum samples contained antibodies to different high-prevalence Kell antigens...
  11. ncbi request reprint Active amino acids of the Kell blood group protein and model of the ectodomain based on the structure of neutral endopeptidase 24.11
    Soohee Lee
    Lindsley F Kimball Research Institute, New York Blood Center, 310 E 67th St, New York, NY 10021, USA
    Blood 102:3028-34. 2003
    ..However, Kell uses different amino acids than NEP in substrate binding and appears to have more flexibility in the composition of amino acids allowed in the active site...
  12. pmc Protein 4.1R-dependent multiprotein complex: new insights into the structural organization of the red blood cell membrane
    Marcela Salomao
    Red Cell Physiology Laboratory and Membrane Biochemistry Laboratory, New York Blood Center, New York, NY 10065, USA
    Proc Natl Acad Sci U S A 105:8026-31. 2008
    ....
  13. pmc Two McLeod patients with novel mutations in XK
    Patrycja M Dubielecka
    New York Blood Center, Lindsley F Kimball Research Institute, Cell Signaling Laboratory, 310E 67th street, New York, NY 10065, USA
    J Neurol Sci 305:160-4. 2011
    ..Patient 2 had a single base substitution in the 3' splice sequence of intron 2 (IVS2-2a>g). In both cases mutations resulted in the absence of XK protein...
  14. pmc Spontaneously arising red cells with a McLeod-like phenotype in normal donors
    David J Araten
    Division of Hematology, Department of Medicine, NYU School of Medicine, New York, NY, United States
    Mutat Res 671:1-5. 2009
    ..004). It may be possible to further investigate the relationship between aging, mutations, and cancer using this approach...
  15. ncbi request reprint The value of DNA analysis for antigens of the Kell and Kx blood group systems
    Soohee Lee
    New York Blood Center, New York, New York 10021, USA
    Transfusion 47:32S-9S. 2007
  16. ncbi request reprint Phenotypic variation among brothers with the McLeod neuroacanthocytosis syndrome
    Ruth H Walker
    Departments of Neurology, Veterans Affairs Medical Center, New York, New York 10468, USA
    Mov Disord 22:244-8. 2007
    ..This phenotypic variation, despite shared mutations, suggests the action of disease-modifying factors that may explain some of the difficulties with genotype-phenotype correlation in McLeod syndrome...
  17. ncbi request reprint Onset of expression of the components of the Kell blood group complex
    Jeffrey J Pu
    Lindsley F Kimball Research Institute of the New York Blood Center, New York, New York 10021, USA
    Transfusion 45:969-74. 2005
    ..Kell surface antigens are expressed early during erythropoiesis but the onset of expression of XK which carries the Kx antigen is unknown...
  18. pmc Molecular basis of two novel and related high-prevalence antigens in the Kell blood group system, KUCI and KANT, and their serologic and spatial association with K11 and KETI
    Randall W Velliquette
    Laboratory of Immunohematology and Genomics, New York Blood Center, Long Island City, New York Laboratory of Immunochemistry, New York Blood Center, New York, New York Laboratory of Molecular Modeling and Drug Design, New York Blood Center, New York, New York Laboratory of Membrane Biochemistry, New York Blood Center, New York, New York Memorial Blood Centers, St Paul, Minnesota Medcenter One, Bismarck, North Dakota National Reference Center for Blood Groups, National Institute of Blood Transfusion, Paris, France Department of Transfusion Medicine, University Hospital Ulm, Institute of Clinical Transfusion Medicine and Immunogenetics, Ulm and German Red Cross Blood Donor Service, Baden W├╝rttemberg Hessen, Institute Ulm, Ulm, Germany Laboratory Services Section, Department of Transfusion Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland American Red Cross, Southern California Region, Pomona, California
    Transfusion 53:2872-81. 2013
    ..Antibodies to antigens in this system can be clinically important. We describe six probands whose plasma contained antibodies to high-prevalence Kell antigens and discuss their relationship...
  19. ncbi request reprint McLeod phenotype without the McLeod syndrome
    Ruth H Walker
    Department of Neurology, James J Peters Veterans Affairs Medical Center, Bronx, NY 10468, USA
    Transfusion 47:299-305. 2007
    ..Here the clinical details of two additional cases are presented, of which the genetic details have previously been published...