Research Topics
Species | J B KostisSummaryAffiliation: New Jersey Country: USA Publications
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Publications
The pharmacokinetics and pharmacodynamics of irbesartan in heart failureJ B Kostis
University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, USA
J Clin Pharmacol 41:935-42. 2001..v. administration is not altered in patients with heart failure. Therefore, this indicates that no dosage adjustment is needed when prescribing irbesartan in heart failure patients...
From hypertension to heart failure: update on the management of systolic and diastolic dysfunctionJohn B Kostis
Department of Medicine, Robert Wood Johnson Medical School, One Robert Wood Johnson Place, Room MEB 491, New Brunswick, NJ 08903, USA
Am J Hypertens 16:18S-22S. 2003..Large-scale trials have shown that betaB significantly reduce risks for morbidity and mortality in patients with HF. Ongoing studies should help to clarify further the optimal cardioprotective therapies in patients with HF...
Efficacy of antithrombotic therapy in chronic heart failure: the HELAS studyDennis V Cokkinos
Cardiology Department, Hippokrateio Hospital, University of Athens, Athens, Greece
Eur J Heart Fail 8:428-32. 2006..8+/-5.3 at baseline, 30.7+/-10 at 2 years, p<0.05). CONCLUSIONS: (1) Overall embolic events are rare in heart failure regardless of treatment. (2) Treatment does not seem to affect outcome...
Erectile dysfunction and cardiac disease: recommendations of the Second Princeton ConferenceRaymond C Rosen
University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, 671 Hoes Lane, Piscataway, NJ 08854, USA
Curr Urol Rep 7:490-6. 2006..Other drug interactions and the cardiovascular safety of testosterone replacement therapy are considered...
Reduction of stroke risk factorsJohn B Kostis
J Clin Hypertens (Greenwich) 9:49-56. 2007..Also participating were Philip B. Gorelick, MD, MPH, Director, Center for Stroke Research, University of Illinois College of Medicine, Chicago, IL, and Franz H. Messerli, MD, St Luke's-Roosevelt Hospital Center, New York, NY...
Incidence and characteristics of angioedema associated with enalaprilJohn B Kostis
Department of Medicine, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick 08903 0019, USA
Arch Intern Med 165:1637-42. 2005..Angioedema is a rare but potentially serious adverse event of angiotensin-converting enzyme inhibitor therapy. However, no prospective, controlled studies have reported on its incidence and clinical characteristics...
Persistence of normotension after discontinuation of lifestyle intervention in the trial of TONE. Trial of Nonpharmacologic Interventions in the ElderlyJohn B Kostis
Department of Medicine, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick 08903 0019, USA
Am J Hypertens 15:732-4. 2002..Weight loss and sodium reduction programs are effective in treating hypertension, but there is little information about the persistence of the benefit after discontinuation of the intervention...
Association of angiotensin-converting enzyme DD genotype with blood pressure sensitivity to weight lossJohn B Kostis
UMDNJ Robert Wood Johnson Medical School, New Brunswick, NJ 08903 0019, USA
Am Heart J 144:625-9. 2002..Salt sensitivity--the degree of blood pressure change in response to a change in sodium load--has been extensively explored. However, the determinants of the extent of blood pressure change after weight reduction have not been evaluated...
Treatment of hypertension in older patients: an updated look at the role of calcium antagonistsJohn B Kostis
Department of Medicine, Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA
Am J Geriatr Cardiol 12:319-27. 2003..Antihypertensive agents with improved tolerability profiles offer the potential for improved blood pressure control...
The importance of managing hypertension and dyslipidemia to decrease cardiovascular diseaseJohn B Kostis
Department of Medicine, UMDNJ Robert Wood Johnson Medical School, Clinical Academic Building, Suite 5200, 125 Paterson Street, New Brunswick, NJ 08903 0019, USA
Cardiovasc Drugs Ther 21:297-309. 2007....
Omapatrilat and enalapril in patients with hypertension: the Omapatrilat Cardiovascular Treatment vs. Enalapril (OCTAVE) trialJohn B Kostis
Department of Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, One Robert Wood Johnson Place, PO Box 19, New Brunswick, NJ 08903 0019, USA
Am J Hypertens 17:103-11. 2004..We compared the efficacy and safety of omapatrilat to a representative angiotensin-converting enzyme (ACE) inhibitor, enalapril...
Sexual dysfunction and cardiac risk (the Second Princeton Consensus Conference)John B Kostis
University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick, NJ, USA
Am J Cardiol 96:313-21. 2005..Finally, further research on the role of PDE-5 inhibition in treating patients with other medical or cardiovascular disorders is recommended...
International medical graduates and the cardiology workforceJohn B Kostis
UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903 0019, USA
J Am Coll Cardiol 44:1172-4. 2004..S. Whether in the absence of a present crisis the projected shortage of cardiologists necessitates change in U.S. immigration policy is an open question...
Disputation on the use of age in determining the need for treatment of hypercholesterolemia and hypertensionJohn B Kostis
Department of Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, 08903-0019, USA
J Clin Hypertens (Greenwich) 8:519-20. 2006
Long-term effect of diuretic-based therapy on fatal outcomes in subjects with isolated systolic hypertension with and without diabetesJohn B Kostis
UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903 0019, USA
Am J Cardiol 95:29-35. 2005..Subjects who had diabetes associated with chlorthalidone had no significant increase in CV events and had a better prognosis than did those who had preexisting diabetes...
Sexual dysfunction and cardiac risk (the Second Princeton Consensus Conference)John B Kostis
University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA
Am J Cardiol 96:85M-93M. 2005..Finally, further research on the role of PDE-5 inhibition in treating patients with other medical or cardiovascular disorders is recommended...
The association of heart failure with insulin resistance and the development of type 2 diabetesJohn B Kostis
Department of Medicine, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903 0019, USA
Am J Hypertens 18:731-7. 2005..The use of vasodilating beta-blockers, on the other hand, has not produced these harmful metabolic effects...
Hypertension: definitions and guidelinesJohn B Kostis
University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA
J Clin Hypertens (Greenwich) 7:538-9. 2005
The benefits of intensive lipid lowering in patients with stable coronary heart disease with normal or high systolic blood pressure: an analysis of the Treating to New Targets (TNT) studyJohn B Kostis
University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, NJ 08903 0019, USA
J Clin Hypertens (Greenwich) 10:367-76. 2008..The effect of lower SBP on stroke was most pronounced in the lowest LDL-C tertile...
Design of the Omapatrilat in Persons with Enhanced Risk of Atherosclerotic events (OPERA) trialJohn B Kostis
University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick 08903 0019, USA
Am J Hypertens 15:193-8. 2002..Additional analyses will be conducted in men and women, in diabetic patients, in different risk classes and according to prior evidence of vascular disease...
Association of increased pulse pressure with the development of heart failure in SHEP. Systolic Hypertension in the Elderly (SHEP) Cooperative Research GroupJ B Kostis
University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick 08903 0019, USA
Am J Hypertens 14:798-803. 2001....
Does withdrawal of antihypertensive medication increase the risk of cardiovascular events? Trial of Nonpharmacologic Interventions in the Elderly (TONE) Cooperative Research GroupJ B Kostis
UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903 0019, USA
Am J Cardiol 82:1501-8. 1998....
Prevention of heart failure by antihypertensive drug treatment in older persons with isolated systolic hypertension. SHEP Cooperative Research GroupJ B Kostis
Department of Medicine, Center for Disease Management and Clinical Outcomes, UMDNJ Robert Wood Johnson Medical School, New Brunswick, NJ 08903 0019, USA
JAMA 278:212-6. 1997..Heart failure is often preceded by isolated systolic hypertension, but the effectiveness of antihypertensive treatment in preventing heart failure is not known...
Association of calcium channel blocker use with increased rate of acute myocardial infarction in patients with left ventricular dysfunctionJ B Kostis
Department of Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick 08903 0019, USA
Am Heart J 133:550-7. 1997..86). The adjusted risk ratio for all-cause mortality associated with CCB use was 1.14 (CI 1.00 to 1.28; p = 0.0454). In this analysis of patients with LVD, CCB use was associated with significantly increased risk of fatal or nonfatal MI...
Time trends in the occurrence and outcome of acute myocardial infarction and coronary heart disease death between 1986 and 1996 (a New Jersey statewide study)J B Kostis
Department of Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903 0019, USA
Am J Cardiol 88:837-41. 2001..Thus, the decrease in age-adjusted CHD mortality is not all due to treatment and true prevention of CHD, but the disease simply occurs at an older age...
Antihypertensive therapy with CCB/ARB combination in older individuals: focus on amlodipine/valsartan combinationJohn B Kostis
Department of Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, NJ 08903 0019, USA
Am J Ther 17:188-96. 2010..In conclusion, combination therapy, including single-pill combination therapy with amlodipine/valsartan, is particularly useful for the management of high-risk individuals such as the elderly...
Association between chlorthalidone treatment of systolic hypertension and long-term survivalJohn B Kostis
Cardiovascular Institute, UMDNJ Robert Wood Johnson Medical School, One Robert Wood Johnson Place, New Brunswick, NJ 08903 0019, USA
JAMA 306:2588-93. 2011....
Effect of atenolol and reserpine on selected events in the systolic hypertension in the elderly program (SHEP)J B Kostis
Department of Medicine, UMDNJ-Robert Wood Johnson Medical School, New Brunswick 08903-0019, USA
Am J Hypertens 8:1147-53. 1995..However, a greater number of patients might have been necessary to adequately evaluate potential differential effects of these drugs, especially for reserpine...
Temporal trends in incidence and long-term case fatality of stroke among children from 1994 to 2007S K Gandhi
Cardiovascular Institute, The Department of Medicine, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick, NJ, USA
Neurology 78:1923-9. 2012..To examine the trends in incidence and long-term case fatality of childhood stroke in New Jersey using a statewide administrative database for the years 1994-2007...
The cost and cardioprotective effects of enalapril in hypertensive patients with left ventricular dysfunctionJ R Cook
Merck and Co, Inc, Whitehouse Station, New Jersey, USA
Am J Hypertens 11:1433-41. 1998..From both the clinical and economic viewpoints, ACE inhibitors provide important clinical benefits and are cost-effective...
Delay in presentation and evaluation for acute stroke: Stroke Time Registry for Outcomes Knowledge and Epidemiology (S.T.R.O.K.E.)C R Lacy
Center for Disease Management and Clinical Outcomes, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick, NJ 08903 0019, USA
Stroke 32:63-9. 2001....
The effect of enalapril on mortal and morbid events in patients with hypertension and left ventricular dysfunctionJ B Kostis
University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903-0019, USA
Am J Hypertens 8:909-14. 1995..866, 0.729, 0.775 and 0.743) history of hypertension as well in those with elevated SBP (RR = 0.841, 0.806, 0.707, 0.867) or DBP (RR = 0.791, 0.889, 0.755, 0.872) at baseline.(ABSTRACT TRUNCATED AT 250 WORDS)..
Trends in incidence and mortality rates of ventricular septal rupture during acute myocardial infarctionAbel E Moreyra
UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA
Am J Cardiol 106:1095-100. 2010....
Aspirin use, dose, and clinical outcomes in postmenopausal women with stable cardiovascular disease: the Women's Health Initiative Observational StudyJeffrey S Berger
Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
Circ Cardiovasc Qual Outcomes 2:78-87. 2009..We sought to evaluate the relationship between aspirin use, dose (81 or 325 mg), and clinical outcomes among postmenopausal women with stable cardiovascular disease (CVD)...
Heart rate and blood pressure response in adult men and women during exercise and sexual activitySebastian T Palmeri
Department of Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA
Am J Cardiol 100:1795-801. 2007..026). In conclusion, sexual activity provides modest physical stress comparable with stage II of the standard multistage Bruce treadmill protocol for men and stage I for women...
Long-term fatal outcomes in subjects with stroke or transient ischemic attack: fourteen-year follow-up of the systolic hypertension in the elderly programAlpesh B Patel
Department of Medicine, UMDNJ Robert Wood Johnson Medical School, One Robert Wood Johnson Pl, PO Box 19, New Brunswick, NJ 08903 0019, USA
Stroke 39:1084-9. 2008..Incident stroke was significantly decreased by treatment in the Systolic Hypertension in Elderly Program (SHEP) Trial, but the reduction in fatal events was not statistically significant...
Lifestyle management of erectile dysfunction: the role of cardiovascular and concomitant risk factorsRaymond C Rosen
Department of Psychiatry, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA
Am J Cardiol 96:76M-79M. 2005..Taken together, these studies support the value of risk factor modification and lifestyle change in the clinical management in men with ED and concomitant cardiovascular illness...
Atrial fibrillation and isolated systolic hypertension: the systolic hypertension in the elderly program and systolic hypertension in the elderly program-extension studyTudor D Vagaonescu
Division of Cardiovascular Diseases and Hypertension, University of Medicine and Dentristy of New Jersey UMDNJ Robert Wood Johnson Medical School, New Brunswick, NJ 08903 0019, USA
Hypertension 51:1552-6. 2008..All-cause mortality and total cardiovascular mortality were significantly increased in hypertensives with atrial fibrillation at 4.7 and 14.3 years follow-up...
Questionable hospital chart documentation practices by physiciansRanita Sharma
UMDNJ Robert Wood Johnson Medical School, New Brunswick, NJ 08903 0019, USA
J Gen Intern Med 23:1865-70. 2008..Physicians, influenced by various pressures, may document information in patient records that they did not personally observe...
Overview of phosphodiesterase 5 inhibition in erectile dysfunctionRaymond C Rosen
Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway, New Jersey 08854, USA
Am J Cardiol 92:9M-18M. 2003..These agents have demonstrated improvement in erectile function and have been shown to be well tolerated in diverse populations comprising thousands of men worldwide. Profiles of these 3 PDE5 inhibitors are reviewed herein...
Permanent pacing is a risk factor for the development of heart failureRonald S Freudenberger
Department of Medicine, Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA
Am J Cardiol 95:671-4. 2005....
Impact of a targeted intervention on lipid-lowering therapy in patients with coronary artery disease in the hospital settingClifton R Lacy
Center for Disease Management and Clinical Outcomes, Division of Cardiovascular Diseases and Hypertension, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick, NJ 08903 0019, USA
Arch Intern Med 162:468-73. 2002..This study was designed to determine the impact of an intervention targeted at improving the use of lipid-lowering therapy in patients with CAD in the hospital setting...
Impact of presentation of research results on likelihood of prescribing medications to patients with left ventricular dysfunctionC R Lacy
Center for Disease Management and Clinical Outcomes, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, New Brunswick 08903-0019, USA
Am J Cardiol 87:203-7. 2001..The high numerical value of relative risk reduction and the concrete and tangible quality of increased life expectancy exert greater influence on health professionals than other standard outcome terms...
Pharmacodynamics and pharmacokinetics of omapatrilat in heart failureJ B Kostis
University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick 08903, USA
J Clin Pharmacol 41:1280-90. 2001..Omapatrilat was well tolerated; differences in systemic exposure and metabolism between CHF patients and controls did not appear to be clinically significant...
Impact of availability of hospital-based invasive cardiac services on racial differences in the use of these servicesP M Gregory
Health Services Research Program, Department of Family Medicine, Robert Wood Johnson Medical School, New Brunswick, NJ 08903 0019, USA
Am Heart J 138:507-17. 1999....
Association of hemostatic factors with peripheral vascular diseaseC S Philipp
Division of Hematology, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick 08904, USA
Am Heart J 134:978-84. 1997..PAI-1 levels were elevated in ADMIT participants, but multivariate analysis did not demonstrate an independent relationship between PAI-1 and ABI...
Meta-analysis, meta-regression, and meta-physicsJohn B Kostis
Robert Wood Johnson University Hospital, New Brunswick, NJ 08903, USA
J Clin Hypertens (Greenwich) 5:64-5,75. 2003
A new approach to primary prevention of cardiovascular diseaseJohn B Kostis
UMDNJ-Robert Wood Johnson Medical School, Division of Cardiology, New Brunswick, NJ, USA
Am J Med 120:746-7. 2007
Effect of anemia on 1-year mortality in patients with acute myocardial infarctionNezar Al Falluji
University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, New Brunswick, NJ 08903-0019, USA
Am Heart J 144:636-41. 2002..The higher unadjusted mortality observed among patients with acute MI and anemia is probably the result of older age, higher comorbidity, and more left ventricular dysfunction...
Comparison of hospital versus out of hospital coronary death rates in women and menYu Hsuan Shao
University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick, NJ, USA
Am J Cardiol 106:26-30. 2010..In conclusion, the greater in-hospital mortality of young women hospitalized for MI compared to young men could be explained in part by the finding that young men were more likely to have out-of-hospital CHD death...
Conjugated equine estrogens and coronary heart disease: the Women's Health InitiativeJudith Hsia
Department of Medicine, George Washington University, Washington, DC, USA
Arch Intern Med 166:357-65. 2006..These trials did not address the role of unopposed estrogen for coronary protection...
Triggering of transmural infarctions, but not nontransmural infarctions, by ambient fine particlesDavid Q Rich
School of Public Health, University of Medicine and Dentistry of New Jersey, Piscataway, New Jersey, USA
Environ Health Perspect 118:1229-34. 2010..Previous studies have reported increased risk of myocardial infarction (MI) after increases in ambient particulate matter (PM) air pollution concentrations in the hours and days before MI onset...
Comparison of rate versus rhythm control for atrial fibrillation in patients with left ventricular dysfunction (from the AFFIRM Study)Ronald S Freudenberger
Department of Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA
Am J Cardiol 100:247-52. 2007..When the data were analyzed by final rhythm status, we again found no significant benefit to patients in the rhythm control arm...
Immediate and 1-year survival of out-of-hospital cardiac arrest victims in southern New Jersey: 1995-2000Maya E Guglin
Cooper Hospital UMDNJ, Camden, New Jersey, USA
Pacing Clin Electrophysiol 27:1072-6. 2004..In southern New Jersey the survival rate did not improve over the 5-year study. Not only initial (prehospital) mortality, but also "delayed" (in-hospital mortality) increases with increase of response time...
The effectiveness of outpatient appointment reminder systems in reducing no-show ratesAmay Parikh
Department of Medicine, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick, NJ, USA
Am J Med 123:542-8. 2010..An automated telephone appointment reminder system may decrease the no-show rate. Understanding characteristics of patients who miss their appointments will aid in the formulation of interventions to reduce no-show rates...
Comparison of pharmacokinetics of lanoteplase and alteplase during acute myocardial infarctionJohn B Kostis
Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, New Brunswick, New Jersey, USA
Clin Pharmacokinet 41:445-52. 2002....
Treatment of octogenarians: should we and howRobert A Phillips
Lenox Hill Hospital and New York University School of Medicine, New York, NY, USA
J Clin Hypertens (Greenwich) 6:267-73; quiz 274-5. 2004
Expanding the definition and classification of hypertensionThomas D Giles
Louisiana State University School of Medicine, New Orleans, LA 70112, USA
J Clin Hypertens (Greenwich) 7:505-12. 2005..We believe it would be preferable to classify all individuals as either normal or hypertensive, based on their cardiovascular evaluation, using the four categories of normal and stages 1, 2, and 3 hypertension...
Treating hypertension in the very oldJohn B Kostis
N Engl J Med 358:1958-60. 2008
Cardiovascular protection using beta-blockers: a critical review of the evidenceSripal Bangalore
St Luke s Roosevelt Hospital and Columbia University, New York, New York 10019, USA
J Am Coll Cardiol 50:563-72. 2007..However, beta-blockers remain very efficacious agents for the treatment of heart failure, certain types of arrhythmia, hypertropic obstructive cardiomyopathy, and in patients with prior myocardial infarction...
Clinical outcomes in antihypertensive treatment of type 2 diabetes, impaired fasting glucose concentration, and normoglycemia: Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)Paul K Whelton
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA
Arch Intern Med 165:1401-9. 2005....
The second Princeton consensus on sexual dysfunction and cardiac risk: new guidelines for sexual medicineGraham Jackson
Cardiothoracic Center, St Thomas Hospital, London, UK
J Sex Med 3:28-36; discussion 36. 2006..The first Princeton Consensus Conference (Princeton I) in 1999 developed guidelines for safe management of cardiac patients regarding sexual activity and the treatment of ED...
Beyond hypertension toward guidelines for cardiovascular risk reductionMassimo Volpe
Department of Cardiology, II Faculty of Medicine, University of Rome La Sapienza Rome, Rome, Italy
Am J Hypertens 17:1068-74. 2004..We propose that global risk should be used as the main determinant of whom to treat, how to treat, and how much to treat...
Treating hypercholesterolemia and hypertension based on lifetime global riskJohn B Kostis
Am J Cardiol 100:138-42. 2007
Safety and efficacy of Atorvastatin-induced very low-density lipoprotein cholesterol levels in Patients with coronary heart disease (a post hoc analysis of the treating to new targets [TNT] study)John C LaRosa
State University of New York Health Science Center, New York, New York, USA
Am J Cardiol 100:747-52. 2007....
Celebrating 50 years of experience: an ECFMG perspectiveJames A Hallock
Educational Commission for Foreign Medical Graduates, Philadelphia, Pennsylvania, USA
Acad Med 81:S7-16. 2006..S. medical graduates. Passage of the USMLE is required for ECFMG Certification and licensure in all jurisdictions...
Erectile dysfunction and incidence of cardiovascular diseaseJohn B Kostis
JAMA 295:1999-2000; author reply 2000. 2006
Hypertension guidelines: criteria that might make them more clinically usefulMichael H Alderman
Department of Epidemiology and Social Medicine, Albert Einstein College of Medicine, Bronx, New York, USA
Am J Hypertens 15:917-23. 2002..Similarly, the benefit of therapy must be assessed by reduction in cardiovascular disease morbidity and mortality...
