W G Johnson

Summary

Affiliation: New Jersey
Country: USA

Publications

  1. ncbi Teratogenic alleles and neurodevelopmental disorders
    William G Johnson
    Department of Neurology, UMDNJ Robert Wood Johnson Medical School, 671 Hoes Lane, Piscataway, NJ 08854, USA
    Bioessays 25:464-77. 2003
  2. ncbi New 19 bp deletion polymorphism in intron-1 of dihydrofolate reductase (DHFR): a risk factor for spina bifida acting in mothers during pregnancy?
    William G Johnson
    Division of Neurogenetics, Department of Neurology, UMDNJ Robert Wood Johnson Medical School, 671 Hoes Lane, Piscataway, NJ 08854, USA
    Am J Med Genet A 124:339-45. 2004
  3. pmc Analysis of case-parent trios at a locus with a deletion allele: association of GSTM1 with autism
    Steven Buyske
    Departments of Statistics and Genetics, 110 Frelinghuysen Rd, Rutgers University, Piscataway, NJ 08854, USA
    BMC Genet 7:8. 2006
  4. doi HLA-DR4 as a risk allele for autism acting in mothers of probands possibly during pregnancy
    William G Johnson
    Department of Neurology, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, 675 Hoes Lane, Piscataway, NJ 08854, USA
    Arch Pediatr Adolesc Med 163:542-6. 2009
  5. ncbi Common dihydrofolate reductase 19-base pair deletion allele: a novel risk factor for preterm delivery
    William G Johnson
    Department of Neurology, University of Medicine and Dentistry New Jersey, Robert Wood Johnson Medical School, Piscataway, NJ, USA
    Am J Clin Nutr 81:664-8. 2005
  6. ncbi DNA polymorphism-diet-cofactor-development hypothesis and the gene-teratogen model for schizophrenia and other developmental disorders
    W G Johnson
    Division of Neurogenetics, Department of Neurology, UMDNJ Robert Wood Johnson Medical School, Piscataway, New Jersey, USA
    Am J Med Genet 88:311-23. 1999
  7. ncbi Folic acid: influence on the outcome of pregnancy
    T O Scholl
    Department of Obstetrics and Gynecology, University of Medicine and Dentistry of New Jersey School of Osteopathic Medicine, Stratford 08084, USA
    Am J Clin Nutr 71:1295S-303S. 2000
  8. ncbi Increased excretion of a lipid peroxidation biomarker in autism
    X Ming
    Department of Neurosciences, UMDNJ New Jersey Medical School, Newark, 07103, USA
    Prostaglandins Leukot Essent Fatty Acids 73:379-84. 2005
  9. doi Genetic variant of glutathione peroxidase 1 in autism
    Xue Ming
    Department of Neurosciences and Neurology, UMDNJ New Jersey Medical School, Newark, 07103, USA
    Brain Dev 32:105-9. 2010
  10. ncbi Short tandem repeat polymorphism linkage studies in a new family with X-linked mental retardation (MRX20)
    A Lazzarini
    Department of Neurology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick 08903, USA
    Am J Med Genet 57:552-7. 1995

Research Grants

Collaborators

Detail Information

Publications17

  1. ncbi Teratogenic alleles and neurodevelopmental disorders
    William G Johnson
    Department of Neurology, UMDNJ Robert Wood Johnson Medical School, 671 Hoes Lane, Piscataway, NJ 08854, USA
    Bioessays 25:464-77. 2003
    ..However, using the special methods required to identify teratogenic alleles is important because this could lead to new approaches to prevention and improved therapy of these disorders...
  2. ncbi New 19 bp deletion polymorphism in intron-1 of dihydrofolate reductase (DHFR): a risk factor for spina bifida acting in mothers during pregnancy?
    William G Johnson
    Division of Neurogenetics, Department of Neurology, UMDNJ Robert Wood Johnson Medical School, 671 Hoes Lane, Piscataway, NJ 08854, USA
    Am J Med Genet A 124:339-45. 2004
    ..About half of dietary folates and all of folic acid supplements must be reduced by DHFR to be available for mother and fetus. Reduced folates could be preferable for supplements during pregnancy to prevent SB...
  3. pmc Analysis of case-parent trios at a locus with a deletion allele: association of GSTM1 with autism
    Steven Buyske
    Departments of Statistics and Genetics, 110 Frelinghuysen Rd, Rutgers University, Piscataway, NJ 08854, USA
    BMC Genet 7:8. 2006
    ..When subjects have already been ascertained in a case-parent design however, the question arises as to whether the data can still be used to test disease association at such a locus...
  4. doi HLA-DR4 as a risk allele for autism acting in mothers of probands possibly during pregnancy
    William G Johnson
    Department of Neurology, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, 675 Hoes Lane, Piscataway, NJ 08854, USA
    Arch Pediatr Adolesc Med 163:542-6. 2009
    ..To test whether HLA-DR4 acts in the mother, possibly during pregnancy, to contribute to the phenotype of autistic disorder in her fetus...
  5. ncbi Common dihydrofolate reductase 19-base pair deletion allele: a novel risk factor for preterm delivery
    William G Johnson
    Department of Neurology, University of Medicine and Dentistry New Jersey, Robert Wood Johnson Medical School, Piscataway, NJ, USA
    Am J Clin Nutr 81:664-8. 2005
    ..Dihydrofolate reductase (DHFR) is required to convert the folic acid used in supplements and for food fortification and the dihydrofolate produced by thymidylate synthase during DNA synthesis to the reduced folate forms used by the cell...
  6. ncbi DNA polymorphism-diet-cofactor-development hypothesis and the gene-teratogen model for schizophrenia and other developmental disorders
    W G Johnson
    Division of Neurogenetics, Department of Neurology, UMDNJ Robert Wood Johnson Medical School, Piscataway, New Jersey, USA
    Am J Med Genet 88:311-23. 1999
    ..A new study design is suggested for identifying teratogenic loci...
  7. ncbi Folic acid: influence on the outcome of pregnancy
    T O Scholl
    Department of Obstetrics and Gynecology, University of Medicine and Dentistry of New Jersey School of Osteopathic Medicine, Stratford 08084, USA
    Am J Clin Nutr 71:1295S-303S. 2000
    ....
  8. ncbi Increased excretion of a lipid peroxidation biomarker in autism
    X Ming
    Department of Neurosciences, UMDNJ New Jersey Medical School, Newark, 07103, USA
    Prostaglandins Leukot Essent Fatty Acids 73:379-84. 2005
    ..These results suggest that the lipid peroxidation biomarker is increased in this cohort of autistic children, especially in the subgroup of autistic children...
  9. doi Genetic variant of glutathione peroxidase 1 in autism
    Xue Ming
    Department of Neurosciences and Neurology, UMDNJ New Jersey Medical School, Newark, 07103, USA
    Brain Dev 32:105-9. 2010
    ....
  10. ncbi Short tandem repeat polymorphism linkage studies in a new family with X-linked mental retardation (MRX20)
    A Lazzarini
    Department of Neurology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick 08903, USA
    Am J Med Genet 57:552-7. 1995
    ..A multipoint lod score of 4.25 was obtained with peak at DXS1003. Recombination events identify a 55.6 cM interval between DXS1068 and DXS454, while a one unit support interval identifies 40 cM between MAOA and DXS458...
  11. ncbi The tau A0 allele in Parkinson's disease
    L I Golbe
    Department of Neurology, UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey 08901, USA
    Mov Disord 16:442-7. 2001
    ..We conclude that the tau protein may play a small role in the pathogenesis of PD and that biochemical characterization of this role may suggest opportunities for PD prophylaxis...
  12. ncbi Risk of autistic disorder in affected offspring of mothers with a glutathione S-transferase P1 haplotype
    Tanishia A Williams
    Department of Neurology, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, Piscataway, NJ 08854, USA
    Arch Pediatr Adolesc Med 161:356-61. 2007
    ..To test whether polymorphisms of the glutathione S-transferase P1 gene (GSTP1) act in the mother during pregnancy to contribute to the phenotype of autistic disorder (AD) in her fetus...
  13. ncbi Possible association of NTDs with a polyhistidine tract polymorphism in the ZIC2 gene
    Lucia Y Brown
    Department of Obstetrics and Gynecology, Columbia University, New York, New York 10032, USA
    Am J Med Genet 108:128-31. 2002
    ..Our sample was too small to reach definitive conclusions, but the evidence is sufficiently intriguing to encourage further research. If this association is confirmed, subtle alterations in ZIC2 activity may confer a risk of NTD...
  14. ncbi Restless legs syndrome: confirmation of linkage to chromosome 12q, genetic heterogeneity, and evidence of complexity
    Alex Desautels
    Centre d Etude du Sommeil, Hopital du Sacre Coeur de Montreal, Canada
    Arch Neurol 62:591-6. 2005
    ..Genes are involved in the etiology of restless legs syndrome, a common sensorimotor disorder...
  15. ncbi Early patterns of care for occupational back pain
    Pierre Cote
    Institute for Work and Health and Department of Public Health Sciences, University of Toronto, Toronto, Ontario, Canada
    Spine (Phila Pa 1976) 30:581-7. 2005
    ..Cross-sectional analysis...
  16. ncbi Timing makes a difference: early nurse case management intervention and low back pain
    Richard J Butler
    Brigham Young University, USA
    Prof Case Manag 12:316-27; quiz 328-9. 2007
    ..To examine whether early nurse contacts influenced self-reported measures of back pain and returns to work...
  17. pmc Patterns of sick-leave and health outcomes in injured workers with back pain
    Pierre Cote
    Centre of Research Expertise in Improved Disability Outcomes, University Health Network Rehabilitation Solutions, Toronto Western Hospital, Toronto, ON, Canada
    Eur Spine J 17:484-93. 2008
    ..Almost a third of workers with an incident episode of back pain experience recurrent spells of work absenteeism during the following year. Our data suggest that stable patterns of sick-leave are associated with better health...

Research Grants1

  1. New DHFR Deletion Polymorphism - A Risk Factor for SB?
    William Johnson; Fiscal Year: 2003
    ..Forms of foliate that are already reduced could be preferable as foliate supplements during pregnancy for prevention of SB. ..