Genomes and Genes
Affiliation: New York University
- Activation of Trk neurotrophin receptors by glucocorticoids provides a neuroprotective effectFreddy Jeanneteau
Molecular Neurobiology Program, Department of Cell Biology, Physiology, Kimmel Center for Biology and Medicine of the Skirball Institute of Biomolecular Medicine, New York University School of Medicine, New York, NY 10016, USA
Proc Natl Acad Sci U S A 105:4862-7. 2008..The ability of GCs to promote Trk receptor activity represents a molecular mechanism that integrates the actions of GCs and neurotrophins...
- Circadian glucocorticoid oscillations promote learning-dependent synapse formation and maintenanceConor Liston
Molecular Neurobiology Program, Skirball Institute, Department of Physiology and Neuroscience, New York University School of Medicine, New York, New York, USA
Nat Neurosci 16:698-705. 2013..They also delineate a new signaling mechanism underlying these effects...
- The MAP kinase phosphatase MKP-1 regulates BDNF-induced axon branchingFreddy Jeanneteau
Molecular Neurobiology Program, Skirball Institute of Biomolecular Medicine, New York, New York, USA
Nat Neurosci 13:1373-9. 2010..Our results identify a signaling mechanism that regulates axonal branching and provide a framework for studying the molecular mechanisms of innervation and axonal remodeling under normal and pathological conditions...
- Promoting neurotrophic effects by GPCR ligandsFreddy Jeanneteau
Molecular Neurobiology Program, Skirball Institute of Biomolecular Medicine, Department of Cell Biology, New York University School of Medicine, NY 10016, USA
Novartis Found Symp 276:181-9; discussion 189-92, 233-7, 275-81. 2006..If small-molecule GPCR ligands can ameliorate neuronal cell loss through Trk, transactivation may offer a new strategy for promoting trophic effects during neurodegeneration...
- CLIC6, a member of the intracellular chloride channel family, interacts with dopamine D(2)-like receptorsNathalie Griffon
Unité de Neurobiologie et Pharmacologie Moléculaire, INSERM U 573, Centre Paul Broca, 2ter rue d Alesia, 75014, Paris, France
Brain Res Mol Brain Res 117:47-57. 2003....
- Glyceraldehyde-3-phosphate dehydrogenase is a GABAA receptor kinase linking glycolysis to neuronal inhibitionJacques J Laschet
Laboratory of Molecular Neurobiology and Pharmacology, Institut National de la Santé et de la Recherche Médicale Unité 573, F 75014 Paris, France
J Neurosci 24:7614-22. 2004..Our results provide a molecular mechanism for the direct involvement of glycolysis in neurotransmission...
- GIPC recruits GAIP (RGS19) to attenuate dopamine D2 receptor signalingFreddy Jeanneteau
Unité de Neurobiologie et Pharmacologie Moléculaire, Institut National de la Sante et de la Recherche Medicale, U 573, Centre Paul Broca, 75104 Paris, France
Mol Biol Cell 15:4926-37. 2004..Since GIPC exclusively interacted with GAIP and selectively with subsets of GPCR, this mechanism may serve to sort GPCR signaling in cells that usually express a large repertoire of GPCRs, G proteins, and RGS...