Leslie I Gold

Summary

Affiliation: New York University School of Medicine
Country: USA

Publications

  1. pmc Estrogen and progesterone regulate p27kip1 levels via the ubiquitin-proteasome system: pathogenic and therapeutic implications for endometrial cancer
    Kuang Tzu Huang
    Department of Medicine, New York University School of Medicine, New York, United States of America
    PLoS ONE 7:e46072. 2012
  2. pmc Inhibitors of SCF-Skp2/Cks1 E3 ligase block estrogen-induced growth stimulation and degradation of nuclear p27kip1: therapeutic potential for endometrial cancer
    Savvas C Pavlides
    PhD, Department of Medicine, Division of Translational Medicine, 550 First Avenue, NB17E4, New York, NY 10016
    Endocrinology 154:4030-45. 2013
  3. pmc Calreticulin: non-endoplasmic reticulum functions in physiology and disease
    Leslie I Gold
    Departments of Medicine and Pathology, New York, University School of Medicine, 550 First Ave, NB16S13 New York, NY 10016 USA
    FASEB J 24:665-83. 2010
  4. doi request reprint Exogenous calreticulin improves diabetic wound healing
    Matthew R Greives
    Department of Medicine and Pathology, New York University School of Medicine, New York, New York 10016, USA
    Wound Repair Regen 20:715-30. 2012
  5. ncbi request reprint Transforming growth factor-beta, estrogen, and progesterone converge on the regulation of p27Kip1 in the normal and malignant endometrium
    Jon Lecanda
    Departments of Pathology and Medicine, NYU Cancer Institute, New York University School of Medicine, New York, NY 10016, USA
    Cancer Res 67:1007-18. 2007
  6. ncbi request reprint Overview of the role for calreticulin in the enhancement of wound healing through multiple biological effects
    Leslie I Gold
    Department of Medicine, New York University School of Medicine, New York, New York 10016, USA
    J Investig Dermatol Symp Proc 11:57-65. 2006
  7. ncbi request reprint TGFbeta prevents proteasomal degradation of the cyclin-dependent kinase inhibitor p27kip1 for cell cycle arrest
    Jon Lecanda
    Department of Medicine and New York University Cancer Institute, New York University School of Medicine, New York, New York 10016, USA
    Cell Cycle 8:742-56. 2009
  8. ncbi request reprint Gene expression studies provide clues to the pathogenesis of uterine leiomyoma: new evidence and a systematic review
    Alan A Arslan
    Department of Obstetrics and Gynecology, Department of Environmental Medicine, Department of Pathology and Department of Medicine, New York University School of Medicine, New York, NY 10016, USA
    Hum Reprod 20:852-63. 2005
  9. ncbi request reprint Binding of polymeric IgG to fibronectin in extracellular matrices: an in vitro paradigm for immune-complex deposition
    Agueda A Rostagno
    Department of Pathology, New York University School of Medicine, 550 First Avenue NB16N28, New York, NY 10017, USA
    Mol Immunol 38:1101-11. 2002
  10. ncbi request reprint Transforming growth factor beta signaling is disabled early in human endometrial carcinogenesis concomitant with loss of growth inhibition
    Trilok V Parekh
    Department of Pathology, Kaplan Comprehensive Cancer Center, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    Cancer Res 62:2778-90. 2002

Collaborators

Detail Information

Publications10

  1. pmc Estrogen and progesterone regulate p27kip1 levels via the ubiquitin-proteasome system: pathogenic and therapeutic implications for endometrial cancer
    Kuang Tzu Huang
    Department of Medicine, New York University School of Medicine, New York, United States of America
    PLoS ONE 7:e46072. 2012
    ..The data implicates that preventing nuclear p27 degradation by blocking Skp2/Cks1-mediated degradation of p27 or increasing Cdh1 to mediate degradation of Skp2-Cks1 are potential strategies for the prevention and treatment of ECA...
  2. pmc Inhibitors of SCF-Skp2/Cks1 E3 ligase block estrogen-induced growth stimulation and degradation of nuclear p27kip1: therapeutic potential for endometrial cancer
    Savvas C Pavlides
    PhD, Department of Medicine, Division of Translational Medicine, 550 First Avenue, NB17E4, New York, NY 10016
    Endocrinology 154:4030-45. 2013
    ..These targeted inhibitors have the potential to be an important therapeutic advance over general proteasome inhibitors for cancers characterized by SCF-Skp2/Cks1-mediated destruction of nuclear p27. ..
  3. pmc Calreticulin: non-endoplasmic reticulum functions in physiology and disease
    Leslie I Gold
    Departments of Medicine and Pathology, New York, University School of Medicine, 550 First Ave, NB16S13 New York, NY 10016 USA
    FASEB J 24:665-83. 2010
    ..Gold, L. I., Eggleton, P., Sweetwyne, M. T., Van Duyn, L. B., Greives, M. R., Naylor, S.-M., Michalak, M., Murphy-Ullrich, J. E. Calreticulin: non-endoplamic reticulum functions in physiology and disease...
  4. doi request reprint Exogenous calreticulin improves diabetic wound healing
    Matthew R Greives
    Department of Medicine and Pathology, New York University School of Medicine, New York, New York 10016, USA
    Wound Repair Regen 20:715-30. 2012
    ..These studies implicate CRT as a potential powerful topical therapeutic agent for the treatment of diabetic and other chronic wounds...
  5. ncbi request reprint Transforming growth factor-beta, estrogen, and progesterone converge on the regulation of p27Kip1 in the normal and malignant endometrium
    Jon Lecanda
    Departments of Pathology and Medicine, NYU Cancer Institute, New York University School of Medicine, New York, NY 10016, USA
    Cancer Res 67:1007-18. 2007
    ..Thus, p27 may be a central target for growth regulation of normal endometrium and in the pathogenesis of ECA...
  6. ncbi request reprint Overview of the role for calreticulin in the enhancement of wound healing through multiple biological effects
    Leslie I Gold
    Department of Medicine, New York University School of Medicine, New York, New York 10016, USA
    J Investig Dermatol Symp Proc 11:57-65. 2006
    ..Thus, CRT profoundly affects the wound healing process by recruiting cells essential for repair into the wound, stimulating cell growth, and increasing extracellular matrix production...
  7. ncbi request reprint TGFbeta prevents proteasomal degradation of the cyclin-dependent kinase inhibitor p27kip1 for cell cycle arrest
    Jon Lecanda
    Department of Medicine and New York University Cancer Institute, New York University School of Medicine, New York, New York 10016, USA
    Cell Cycle 8:742-56. 2009
    ..The TGFbeta/p27 axis might provide novel therapeutic targets for cancer...
  8. ncbi request reprint Gene expression studies provide clues to the pathogenesis of uterine leiomyoma: new evidence and a systematic review
    Alan A Arslan
    Department of Obstetrics and Gynecology, Department of Environmental Medicine, Department of Pathology and Department of Medicine, New York University School of Medicine, New York, NY 10016, USA
    Hum Reprod 20:852-63. 2005
    ..Familial and epidemiological studies provide compelling evidence that genetic alterations play an important role in leiomyoma development...
  9. ncbi request reprint Binding of polymeric IgG to fibronectin in extracellular matrices: an in vitro paradigm for immune-complex deposition
    Agueda A Rostagno
    Department of Pathology, New York University School of Medicine, 550 First Avenue NB16N28, New York, NY 10017, USA
    Mol Immunol 38:1101-11. 2002
    ....
  10. ncbi request reprint Transforming growth factor beta signaling is disabled early in human endometrial carcinogenesis concomitant with loss of growth inhibition
    Trilok V Parekh
    Department of Pathology, Kaplan Comprehensive Cancer Center, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    Cancer Res 62:2778-90. 2002
    ....