Research Topics
| Ute FrevertSummaryAffiliation: New York University Country: USA Publications
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Detail Information
Publications
Exoerythrocytic development of Plasmodium gallinaceum in the White Leghorn chickenUte Frevert
Department of Medical Parasitology, New York University School of Medicine, New York, NY 10010, USA
Int J Parasitol 38:655-72. 2008....
Plasmodium sporozoite passage across the sinusoidal cell layerUte Frevert
NYU School of Medicine, Department of Medical Parasitology, 341 E 25 Street, New York, New York 10010, USA
Subcell Biochem 47:182-97. 2008..Recent cell biological, microscopic, and genetic approaches have considerably enhanced our understanding of the initial events leading to the establishment of a malaria infection in the liver...- Sneaking in through the back entrance: the biology of malaria liver stagesUte Frevert
Department of Medical and Molecular Parasitology, New York University School of Medicine, 341 E 25 Street, New York, NY 10010, USA
Trends Parasitol 20:417-24. 2004..By choosing the liver as their initial site of replication, Plasmodium sporozoites can exploit the tolerogenic properties of this unique immune organ to evade the host's immune response... - Nomadic or sessile: can Kupffer cells function as portals for malaria sporozoites to the liver?Ute Frevert
Department of Medical Parasitology, New York University School of Medicine, New York, NY 10010, USA
Cell Microbiol 8:1537-46. 2006.... - Intravital observation of Plasmodium berghei sporozoite infection of the liverUte Frevert
Department of Medical and Molecular Parasitology, New York University School of Medicine, New York, New York, USA
PLoS Biol 3:e192. 2005..In summary, malaria sporozoites bind tightly to the sinusoidal cell layer, cross Kupffer cells, and leave behind a trail of dead hepatocytes when migrating to their final destination in the liver... - Malaria circumsporozoite protein inhibits the respiratory burst in Kupffer cellsIvan Usynin
Department of Medical Parasitology, New York University School of Medicine, 341 E 25 St, New York, NY 10010, USA
Cell Microbiol 9:2610-28. 2007..This allows the sporozoites to safely pass through these professional phagocytes and to develop inside neighbouring hepatocytes... - Plasmodium yoelii sporozoites modulate cytokine profile and induce apoptosis in murine Kupffer cellsChristian Klotz
Department of Medical Parasitology, New York University School of Medicine, 341 E 25 Street, New York, NY 10010, USA
Int J Parasitol 38:1639-50. 2008..Together, the in vitro data indicate that Plasmodium possesses mechanisms to render Kupffer cells insensitive to pro-inflammatory stimuli and eventually eliminates these macrophages by forcing them into programmed cell death... - Imaging effector functions of human cytotoxic CD4+ T cells specific for Plasmodium falciparum circumsporozoite proteinUte Frevert
Department of Medical Parasitology, New York University School of Medicine, 341 E 25 St, New York, NY 10010, USA
Int J Parasitol 39:119-32. 2009.... - Release of hepatic Plasmodium yoelii merozoites into the pulmonary microvasculatureKerstin Baer
Department of Medical Parasitology, New York University School of Medicine, New York, New York, United States of America
PLoS Pathog 3:e171. 2007..We believe this previously unknown part of the plasmodial life cycle ensures an effective transition from the liver to the blood phase of the malaria infection... - Intravital microscopy demonstrating antibody-mediated immobilisation of Plasmodium berghei sporozoites injected into skin by mosquitoesJerome P Vanderberg
Department of Medical and Molecular Parasitology, New York University School of Medicine, 341 East 25th Street, New York, NY 10010, USA
Int J Parasitol 34:991-6. 2004.... - Kupffer cells are obligatory for Plasmodium yoelii sporozoite infection of the liverKerstin Baer
Department of Medical Parasitology, New York University School of Medicine, 341 E 25 St, New York, NY 10010, USA
Cell Microbiol 9:397-412. 2007..Together these data provide strong support for the hypothesis that Kupffer cells are the portal for sporozoites to hepatocytes and critical for the onset of a malaria infection... - Arrest in the liver--a genetically defined malaria vaccine?Ute Frevert
Department of Medical and Molecular Parasitology, New York University School of Medicine, New York, USA
N Engl J Med 352:1600-2. 2005 
Cellular effector mechanisms against Plasmodium liver stagesUte Frevert
Department of Medical Parasitology, New York University School of Medicine, 341 E 25 St, New York, NY 10010, USA
Cell Microbiol 10:1956-67. 2008..Considering the unique immune properties of the liver, it is conceivable that these different hepatic antigen-presenting cells fulfil distinct but complementary roles during the effector phase against Plasmodium liver stages...- Compounds of the upper gastrointestinal tract induce rapid and efficient excystation of Entamoeba invadensBiswa Nath Mitra
Department of Medical Parasitology, New York University School of Medicine, NY 10010, USA
Int J Parasitol 40:751-60. 2010.... - Neuroimmunological blood brain barrier opening in experimental cerebral malariaAdéla Nacer
Division of Medical Parasitology, Department of Microbiology, New York University School of Medicine, New York, New York, United States of America
PLoS Pathog 8:e1002982. 2012..Thus, it appears that neurological signs and coma in ECM are due to regulated opening of paracellular-junctional and transcellular-vesicular fluid transport pathways at the neuroimmunological BBB... - Defective sorting of the thrombospondin-related anonymous protein (TRAP) inhibits Plasmodium infectivityPurnima Bhanot
Michael Heidelberger Division of Immunology, Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
Mol Biochem Parasitol 126:263-73. 2003..However, there is no significant difference in the amounts of TRAP secreted into the culture medium by wild type and mutant parasites, suggesting that TRAP destined for secretion bypasses micronemal localization... - Proteoglycans mediate malaria sporozoite targeting to the liverGabriele Pradel
Department of Medical and Molecular Parasitology, New York University School of Medicine, New York 10010, USA
Mol Microbiol 45:637-51. 2002.... - Quantitative isolation and in vivo imaging of malaria parasite liver stagesAlice S Tarun
Seattle Biomedical Research Institute, Seattle, WA 98109, USA
Int J Parasitol 36:1283-93. 2006..Intravital imaging thus reveals new, important information on the malaria parasite's transition from tissue to blood stage... - Plasmodium liver stage developmental arrest by depletion of a protein at the parasite-host interfaceAnn-Kristin Mueller
Department of Parasitology, Heidelberg University School of Medicine, 69120 Heidelberg, Germany
Proc Natl Acad Sci U S A 102:3022-7. 2005..Genetically attenuated liver stages may thus induce immune responses, which inhibit subsequent infection of the liver with WT parasites... - A mosquito-specific protein family includes candidate receptors for malaria sporozoite invasion of salivary glandsSvetlana Korochkina
Center for Microbial and Plant Genomics, and Department of Microbiology, University of Minnesota, St Paul, MN 55108, USA
Cell Microbiol 8:163-75. 2006..Phylogenomic analysis suggests that an SGS ancestor was involved in a lateral gene transfer...