Dorothy A Frenz

Summary

Affiliation: New York Medical College
Country: USA

Publications

  1. pmc Retinoid signaling in inner ear development: A "Goldilocks" phenomenon
    Dorothy A Frenz
    Department of Otorhinolaryngology Head and Neck Surgery, Albert Einstein College of Medicine, Bronx, New York, USA
    Am J Med Genet A 152:2947-61. 2010
  2. doi request reprint Retinoic acid-induced inner ear teratogenesis caused by defective Fgf3/Fgf10-dependent Dlx5 signaling
    Wei Liu
    Department of Otorhinolaryngology Head and Neck Surgery, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Birth Defects Res B Dev Reprod Toxicol 83:134-44. 2008
  3. doi request reprint Coordinated molecular control of otic capsule differentiation: functional role of Wnt5a signaling and opposition by sfrp3 activity
    Wei Liu
    Department of Otorhinolaryngology Head and Neck Surgery, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Growth Factors 26:343-54. 2008
  4. ncbi request reprint Transforming growth factor-beta1 signaling participates in the physiological and pathological regulation of mouse inner ear development by all-trans retinoic acid
    Sydney C Butts
    Department of Otolaryngology, Albert Einstein College of Medicine, 1410 Pelham Parkway South, Bronx, NY 10461, USA
    Birth Defects Res A Clin Mol Teratol 73:218-28. 2005
  5. ncbi request reprint Negative regulation of otic capsule chondrogenesis: it can make you Smad
    Wei Liu
    Department of Otorhinolaryngology, Head, and Neck Surgery, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Ann N Y Acad Sci 1116:141-8. 2007
  6. ncbi request reprint Bone morphogenetic protein 4 (BMP4): a regulator of capsule chondrogenesis in the developing mouse inner ear
    Wei Liu
    Department of Otolaryngology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Dev Dyn 226:427-38. 2003
  7. ncbi request reprint Oral ethanol potentiates the loss of outer hair cells in cisplatin-exposed rats
    Dilip Madnani
    Department of Otorhinolaryngology Head and Neck Surgery, Albert Einstein College of Medicine, Bronx, NY, USA
    Otolaryngol Head Neck Surg 137:327-31. 2007

Collaborators

Detail Information

Publications7

  1. pmc Retinoid signaling in inner ear development: A "Goldilocks" phenomenon
    Dorothy A Frenz
    Department of Otorhinolaryngology Head and Neck Surgery, Albert Einstein College of Medicine, Bronx, New York, USA
    Am J Med Genet A 152:2947-61. 2010
    ..We conclude that RA coordinates inner ear morphogenesis by controlling an FGF/Dlx signaling cascade, whose perturbation by deviations in local retinoid concentrations can lead to inner ear dysmorphogenesis...
  2. doi request reprint Retinoic acid-induced inner ear teratogenesis caused by defective Fgf3/Fgf10-dependent Dlx5 signaling
    Wei Liu
    Department of Otorhinolaryngology Head and Neck Surgery, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Birth Defects Res B Dev Reprod Toxicol 83:134-44. 2008
    ..Retinoic acid (RA) is essential for inner ear development. However, exposure to excess RA at a critical period leads to inner ear defects. These defects are associated with disruption in epithelial-mesenchymal interactions...
  3. doi request reprint Coordinated molecular control of otic capsule differentiation: functional role of Wnt5a signaling and opposition by sfrp3 activity
    Wei Liu
    Department of Otorhinolaryngology Head and Neck Surgery, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Growth Factors 26:343-54. 2008
    ..Our findings support Wnt5a and sfrp3 as regulators of otic capsule formation in the developing mouse inner ear...
  4. ncbi request reprint Transforming growth factor-beta1 signaling participates in the physiological and pathological regulation of mouse inner ear development by all-trans retinoic acid
    Sydney C Butts
    Department of Otolaryngology, Albert Einstein College of Medicine, 1410 Pelham Parkway South, Bronx, NY 10461, USA
    Birth Defects Res A Clin Mol Teratol 73:218-28. 2005
    ....
  5. ncbi request reprint Negative regulation of otic capsule chondrogenesis: it can make you Smad
    Wei Liu
    Department of Otorhinolaryngology, Head, and Neck Surgery, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Ann N Y Acad Sci 1116:141-8. 2007
    ..The importance of otic capsule chondrogenic control and implications of Smad signaling for otosclerosis, a disease affecting the endochondral bony labyrinth, are indicated...
  6. ncbi request reprint Bone morphogenetic protein 4 (BMP4): a regulator of capsule chondrogenesis in the developing mouse inner ear
    Wei Liu
    Department of Otolaryngology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    Dev Dyn 226:427-38. 2003
    ..Our findings support BMP4 as an essential mediator of chondrogenesis in the developing otic capsule in situ...
  7. ncbi request reprint Oral ethanol potentiates the loss of outer hair cells in cisplatin-exposed rats
    Dilip Madnani
    Department of Otorhinolaryngology Head and Neck Surgery, Albert Einstein College of Medicine, Bronx, NY, USA
    Otolaryngol Head Neck Surg 137:327-31. 2007
    ..The aim of this study was to examine the effect of oral ethanol on cisplatin ototoxicity...