T F Franke

Summary

Affiliation: New York University School of Medicine
Country: USA

Publications

  1. ncbi PI3K/Akt: getting it right matters
    T F Franke
    Department of Psychiatry, New York University School of Medicine, New York, NY 10016, USA
    Oncogene 27:6473-88. 2008
  2. ncbi Astrocyte elevated gene-1 activates cell survival pathways through PI3K-Akt signaling
    S G Lee
    Department of Urology, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, College of Physicians and Surgeons, New York, NY 10032, USA
    Oncogene 27:1114-21. 2008
  3. ncbi Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1
    A H Kim
    Molecular Neurobiology Program, Skirball Institute for Biomolecular Medicine, New York University School of Medicine, New York, New York 10016, USA
    Mol Cell Biol 21:893-901. 2001
  4. ncbi Characterization of a novel isoform of caspase-9 that inhibits apoptosis
    J M Angelastro
    Department of Pathology, Center for Neurobiology and Behavior, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    J Biol Chem 276:12190-200. 2001

Collaborators

Detail Information

Publications4

  1. ncbi PI3K/Akt: getting it right matters
    T F Franke
    Department of Psychiatry, New York University School of Medicine, New York, NY 10016, USA
    Oncogene 27:6473-88. 2008
    ..An emphasis is placed on the involvement of Akt in human diseases ranging from cancer to metabolic dysfunction and mental disease...
  2. ncbi Astrocyte elevated gene-1 activates cell survival pathways through PI3K-Akt signaling
    S G Lee
    Department of Urology, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, College of Physicians and Surgeons, New York, NY 10032, USA
    Oncogene 27:1114-21. 2008
    ..Activation of survival pathways may be one mechanism by which AEG-1 exerts its oncogenic properties...
  3. ncbi Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1
    A H Kim
    Molecular Neurobiology Program, Skirball Institute for Biomolecular Medicine, New York University School of Medicine, New York, New York 10016, USA
    Mol Cell Biol 21:893-901. 2001
    ..These results provide the first direct link between Akt and the family of stress-activated kinases...
  4. ncbi Characterization of a novel isoform of caspase-9 that inhibits apoptosis
    J M Angelastro
    Department of Pathology, Center for Neurobiology and Behavior, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    J Biol Chem 276:12190-200. 2001
    ..Taken together, our observations indicate that casp-9-CTD acts as a dominant-negative variant. Its expression in various tissues indicates a physiological role in regulating cell death...