S Formenti

Summary

Affiliation: New York University
Country: USA

Publications

  1. ncbi request reprint T1 stage breast cancer: adjuvant hypofractionated conformal radiation therapy to tumor bed in selected postmenopausal breast cancer patients--pilot feasibility study
    Silvia C Formenti
    Department of Radiation Oncology, New York University School of Medicine, 566 First Ave, New York, NY 10016, USA
    Radiology 222:171-8. 2002
  2. ncbi request reprint Expression of metastases-associated genes in cervical cancers resected in the proliferative and secretory phases of the menstrual cycle
    S Formenti
    Department of Radiation Oncology, New York University School of Medicine, New York 10016, USA
    Clin Cancer Res 6:4653-7. 2000
  3. pmc Local control by radiotherapy: is that all there is?
    Silvia C Formenti
    Department of Radiation Oncology, New York University School of Medicine and NYU Cancer Institute, 160 East 34th Street, New York, NY 10016, USA
    Breast Cancer Res 10:215. 2008
  4. ncbi request reprint Phase I-II trial of prone accelerated intensity modulated radiation therapy to the breast to optimally spare normal tissue
    Silvia C Formenti
    Department of Radiation Oncology, Division of Biostatistics, New York University Cancer Institute and New York University School of Medicine, New York, NY 10016, USA
    J Clin Oncol 25:2236-42. 2007
  5. pmc Systemic effects of local radiotherapy
    Silvia C Formenti
    Department of Radiation Oncology, NYU Langone Medical Center and NYU Cancer Institute, New York University School of Medicine, New York, NY 10016, USA
    Lancet Oncol 10:718-26. 2009
  6. ncbi request reprint External-beam partial-breast irradiation
    Silvia C Formenti
    Departmetn of Radiation Oncology, New York University School of Medicine, New York, NY, USA
    Semin Radiat Oncol 15:92-9. 2005
  7. ncbi request reprint Prone accelerated partial breast irradiation after breast-conserving surgery: preliminary clinical results and dose-volume histogram analysis
    Silvia C Formenti
    Department of Radiation Oncology, New York University School of Medicine, New York, New York, USA
    Int J Radiat Oncol Biol Phys 60:493-504. 2004
  8. ncbi request reprint Low HER2/neu gene expression is associated with pathological response to concurrent paclitaxel and radiation therapy in locally advanced breast cancer
    Silvia C Formenti
    Radiation Oncology and Medicine, New York University School of Medicine, New York, NY 10016, USA
    Int J Radiat Oncol Biol Phys 52:397-405. 2002
  9. ncbi request reprint Preoperative twice-weekly paclitaxel with concurrent radiation therapy followed by surgery and postoperative doxorubicin-based chemotherapy in locally advanced breast cancer: a phase I/II trial
    Silvia C Formenti
    Kaplan Comprehensive Cancer Center, New York University School of Medicine, New York, NY, USA
    J Clin Oncol 21:864-70. 2003
  10. ncbi request reprint Novel approaches to postoperative radiation therapy as part of breast-conserving therapy for early-stage breast cancer
    Minh Tam Truong
    Department of Radiation Oncology, New York University School of Medicine, New York, NY 10013, USA
    Clin Breast Cancer 4:253-63. 2003

Collaborators

Detail Information

Publications40

  1. ncbi request reprint T1 stage breast cancer: adjuvant hypofractionated conformal radiation therapy to tumor bed in selected postmenopausal breast cancer patients--pilot feasibility study
    Silvia C Formenti
    Department of Radiation Oncology, New York University School of Medicine, 566 First Ave, New York, NY 10016, USA
    Radiology 222:171-8. 2002
    ..To explore the feasibility of a short course of hypofractionated conformal radiation therapy to the tumor bed as part of a breast preservation protocol in postmenopausal patients with nonpalpable pT1N0 stage breast cancer...
  2. ncbi request reprint Expression of metastases-associated genes in cervical cancers resected in the proliferative and secretory phases of the menstrual cycle
    S Formenti
    Department of Radiation Oncology, New York University School of Medicine, New York 10016, USA
    Clin Cancer Res 6:4653-7. 2000
    ..These findings need to be replicated, and their implications for tumor angiogenesis, invasion, and metastatic propensity need to be explored both in human studies and in experimental models...
  3. pmc Local control by radiotherapy: is that all there is?
    Silvia C Formenti
    Department of Radiation Oncology, New York University School of Medicine and NYU Cancer Institute, 160 East 34th Street, New York, NY 10016, USA
    Breast Cancer Res 10:215. 2008
    ....
  4. ncbi request reprint Phase I-II trial of prone accelerated intensity modulated radiation therapy to the breast to optimally spare normal tissue
    Silvia C Formenti
    Department of Radiation Oncology, Division of Biostatistics, New York University Cancer Institute and New York University School of Medicine, New York, NY 10016, USA
    J Clin Oncol 25:2236-42. 2007
    ..To report the clinical feasibility of a trial of accelerated whole-breast intensity modulated radiotherapy, with the patient in prone position, optimally to spare the heart and lung...
  5. pmc Systemic effects of local radiotherapy
    Silvia C Formenti
    Department of Radiation Oncology, NYU Langone Medical Center and NYU Cancer Institute, New York University School of Medicine, New York, NY 10016, USA
    Lancet Oncol 10:718-26. 2009
    ..Local radiation also triggers systemic effects that can be used in combination with immunotherapy to induce responses outside the radiation field...
  6. ncbi request reprint External-beam partial-breast irradiation
    Silvia C Formenti
    Departmetn of Radiation Oncology, New York University School of Medicine, New York, NY, USA
    Semin Radiat Oncol 15:92-9. 2005
    ..This review focuses on the rationale and the reported studies of external-beam partial-breast radiation and identifies some specific issues and remaining problems associated with this approach...
  7. ncbi request reprint Prone accelerated partial breast irradiation after breast-conserving surgery: preliminary clinical results and dose-volume histogram analysis
    Silvia C Formenti
    Department of Radiation Oncology, New York University School of Medicine, New York, New York, USA
    Int J Radiat Oncol Biol Phys 60:493-504. 2004
    ..Patients were treated in the prone position with three-dimensional conformal radiotherapy after breast-conserving surgery...
  8. ncbi request reprint Low HER2/neu gene expression is associated with pathological response to concurrent paclitaxel and radiation therapy in locally advanced breast cancer
    Silvia C Formenti
    Radiation Oncology and Medicine, New York University School of Medicine, New York, NY 10016, USA
    Int J Radiat Oncol Biol Phys 52:397-405. 2002
    ....
  9. ncbi request reprint Preoperative twice-weekly paclitaxel with concurrent radiation therapy followed by surgery and postoperative doxorubicin-based chemotherapy in locally advanced breast cancer: a phase I/II trial
    Silvia C Formenti
    Kaplan Comprehensive Cancer Center, New York University School of Medicine, New York, NY, USA
    J Clin Oncol 21:864-70. 2003
    ..We investigated the safety and efficacy of primary twice-weekly paclitaxel and concurrent radiation (RT) before modified radical mastectomy followed by adjuvant doxorubicin-based chemotherapy...
  10. ncbi request reprint Novel approaches to postoperative radiation therapy as part of breast-conserving therapy for early-stage breast cancer
    Minh Tam Truong
    Department of Radiation Oncology, New York University School of Medicine, New York, NY 10013, USA
    Clin Breast Cancer 4:253-63. 2003
    ..This article reviews the available data and the current ongoing research on novel RT techniques and fractionation schedules in BCT for early-stage breast cancer...
  11. ncbi request reprint Ethical, legal, and social issues related to genomics and cancer research: the impending crisis
    Bruce E Ellerin
    Department of Radiation Oncology, New York University School of Medicine, New York, NY 10016 6497, USA
    J Am Coll Radiol 2:919-26. 2005
    ....
  12. ncbi request reprint Possession of ATM sequence variants as predictor for late normal tissue responses in breast cancer patients treated with radiotherapy
    Alice Y Ho
    Department of Radiation Oncology, Mount Sinai School of Medicine, New York, NY 10029, USA
    Int J Radiat Oncol Biol Phys 69:677-84. 2007
    ..The ATM gene product is a central component of cell cycle regulation and genomic surveillance. We hypothesized that DNA sequence alterations in ATM predict for adverse effects after external beam radiotherapy for early breast cancer...
  13. ncbi request reprint External-beam-based partial breast irradiation
    Silvia C Formenti
    Department of Radiation Oncology, New York University School of Medicine, New York, NY 10016, USA
    Nat Clin Pract Oncol 4:326-7. 2007
  14. ncbi request reprint Accelerated intensity-modulated radiotherapy to breast in prone position: dosimetric results
    J Keith Dewyngaert
    Department of Radiation Oncology, New York University School of Medicine, 160 E 34th Street, New York, NY 10016, USA
    Int J Radiat Oncol Biol Phys 68:1251-9. 2007
    ..To report the physics and dosimetry results of a trial of accelerated intensity-modulated radiotherapy to the whole breast with a concomitant boost to the tumor bed in patients treated in the prone position...
  15. pmc Inhibition of integrin alpha(v)beta6, an activator of latent transforming growth factor-beta, prevents radiation-induced lung fibrosis
    Khalid Puthawala
    New York University School of Medicine, Department of Medicine, New York, NY 10282, USA
    Am J Respir Crit Care Med 177:82-90. 2008
    ..Because the integrin alpha(v)beta6 is a major TGF-beta activator in the lung, inhibition of alpha(v)beta6-mediated TGF-beta activation is a logical strategy to treat lung fibrosis...
  16. ncbi request reprint A hypoxia-controlled cap-dependent to cap-independent translation switch in breast cancer
    Steve Braunstein
    Department of Microbiology, New York University School of Medicine, New York, NY 10016, USA
    Mol Cell 28:501-12. 2007
    ..The switch from cap-dependent to cap-independent mRNA translation facilitates tumor angiogenesis and hypoxia responses in animal models...
  17. doi request reprint Acquisition of stable inducible up-regulation of nuclear factor-kappaB by tumor necrosis factor exposure confers increased radiation resistance without increased transformation in breast cancer cells
    Steve Braunstein
    Department of Microbiology, New York University School of Medicine, New York, NY 10016, USA
    Mol Cancer Res 6:78-88. 2008
    ..Greater cell survival despite increased genomic injury may permit increased acquisition of malignant genetic alterations as well as resistance to chemoradiation therapy...
  18. doi request reprint Phase I/II study of biweekly paclitaxel and radiation in androgen-ablated locally advanced prostate cancer
    Nicholas J Sanfilippo
    Department of Radiation Oncology, New York University School of Medicine, New York, NY, USA
    J Clin Oncol 26:2973-8. 2008
    ..To determine the maximum-tolerated dose (MTD) of concurrent paclitaxel and radiation therapy (RT) in patients with locally advanced prostate cancer...
  19. pmc Antiangiogenic effects of noscapine enhance radioresponse for GL261 tumors
    Elizabeth W Newcomb
    Department of Pathology, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    Int J Radiat Oncol Biol Phys 71:1477-84. 2008
    ..To assess the effects of noscapine, a tubulin-binding drug, in combination with radiation in a murine glioma model...
  20. pmc Radiation-induced CXCL16 release by breast cancer cells attracts effector T cells
    Satoko Matsumura
    Department of Pathology, New York University School of Medicine, New York, USA
    J Immunol 181:3099-107. 2008
    ..The ability of IR to convert tumors into "inflamed" peripheral tissues could be exploited to overcome obstacles at the effector phase of the antitumor immune response and improve the therapeutic efficacy of immunotherapy...
  21. doi request reprint Prone-breast radiotherapy: too early for conclusions: in regard to Chino et Al. (Int j radiat oncol biol phys 2008;70:916-920)
    Stella C Lymberis
    Int J Radiat Oncol Biol Phys 72:301-2; author reply 302. 2008
  22. ncbi request reprint External beam partial-breast radiotherapy: crucial differences between NYU 00-23 and RTOG 0319: in regard to Vicini et al. (Int J Radiat Oncol Biol Phys 2005;63:1531-1537)
    Silvia C Formenti
    Int J Radiat Oncol Biol Phys 66:630; author reply 630-1. 2006
  23. ncbi request reprint The combination of ionizing radiation and peripheral vaccination produces long-term survival of mice bearing established invasive GL261 gliomas
    Elizabeth W Newcomb
    Department of Pathology, New York University School of Medicine, New York, New York 10016, USA
    Clin Cancer Res 12:4730-7. 2006
    ..Here, we tested the hypothesis that whole-brain radiotherapy (WBRT) up-regulates MHC-I expression on GL261 tumors and enhances the effectiveness of immunotherapy...
  24. ncbi request reprint Immune-mediated inhibition of metastases after treatment with local radiation and CTLA-4 blockade in a mouse model of breast cancer
    Sandra Demaria
    Department of Pathology, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    Clin Cancer Res 11:728-34. 2005
    ..Here we tested the hypothesis that the combination of RT to the primary tumor with CTLA-4 blockade can elicit antitumor immunity inhibiting the metastases...
  25. ncbi request reprint Select forms of tumor cell apoptosis induce dendritic cell maturation
    Sandra Demaria
    MSB 563, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    J Leukoc Biol 77:361-8. 2005
    ..These data have important implications for the effects of chemotherapy on antitumor immunity in solid and hematologic malignancies...
  26. ncbi request reprint Ionizing radiation inhibition of distant untreated tumors (abscopal effect) is immune mediated
    Sandra Demaria
    Department of Pathology, New York University School of Medicine, New York, New York, USA
    Int J Radiat Oncol Biol Phys 58:862-70. 2004
    ..We therefore tested the hypothesis that the abscopal effect elicited by radiation is immune mediated. This was directly tested by enhancing the number of available dendritic cells using the growth factor Flt3-Ligand (Flt3-L)...
  27. pmc Combining radiotherapy and immunotherapy: a revived partnership
    Sandra Demaria
    Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
    Int J Radiat Oncol Biol Phys 63:655-66. 2005
    ..In addition, the experimental evidence supporting the contention that RT can be used as a tool to induce antitumor immunity is discussed, and a new approach to radioimmunotherapy of cancer is proposed...
  28. ncbi request reprint In regard to Kao et al.: concomitant radiation therapy and paclitaxel for unresectable locally advanced breast cancer: results from two consecutive phase I/II trials (Int J Radiat Oncol Biol Phys 2005;61:1045-1053)
    Silvia C Formenti
    Int J Radiat Oncol Biol Phys 63:1275-6. 2005
  29. ncbi request reprint Radiation sensitivity of GL261 murine glioma model and enhanced radiation response by flavopiridol
    Elizabeth W Newcomb
    Department of Pathology, New York University Cancer Institute, New York University School of Medicine, New York, New York, USA
    Cell Cycle 5:93-9. 2006
    ....
  30. ncbi request reprint ATM sequence variants and risk of radiation-induced subcutaneous fibrosis after postmastectomy radiotherapy
    Christian N Andreassen
    Department of Experimental Clinical Oncology, Aarhus University Hospital, Aarhus, Denmark
    Int J Radiat Oncol Biol Phys 64:776-83. 2006
    ....
  31. ncbi request reprint The vitamin-like dietary supplement para-aminobenzoic acid enhances the antitumor activity of ionizing radiation
    Sandhya Xavier
    Department of Radiation Oncology and Cell Biology, The NYU Cancer Institute, New York University School of Medicine, New York, NY 10016, USA
    Int J Radiat Oncol Biol Phys 65:517-27. 2006
    ..To determine whether para-aminobenzoic acid (PABA) alters the sensitivity of tumor cells to ionizing radiation in vitro and in vivo...
  32. ncbi request reprint Genetic predictors of adverse radiotherapy effects: the Gene-PARE project
    Alice Y Ho
    Department of Radiation Oncology, Mount Sinai School of Medicine, New York, NY, USA
    Int J Radiat Oncol Biol Phys 65:646-55. 2006
    ..The purpose of the Genetic Predictors of Adverse Radiotherapy Effects (Gene-PARE) project is to help achieve this goal...
  33. ncbi request reprint Ionizing radiation modulates the exposure of the HUIV26 cryptic epitope within collagen type IV during angiogenesis
    Peter C Brooks
    Departments of Radiation Oncology and Cell Biology, The Kaplan Cancer Center, New York University School of Medicine, Rusk Building Room 806, 400 East 34th Street, New York, NY 10016, USA
    Int J Radiat Oncol Biol Phys 54:1194-201. 2002
    ..We have hypothesized that ionizing radiation might affect the process of angiogenesis through a direct effect on the extracellular matrix and specifically on collagen Type IV...
  34. ncbi request reprint Biologic comparison of partial breast irradiation protocols
    Barry S Rosenstein
    Department of Radiation Oncology, Mount Sinai School of Medicine, New York, NY 10029, USA
    Int J Radiat Oncol Biol Phys 60:1393-404. 2004
    ....
  35. ncbi request reprint Pharmacogenomics and breast cancer
    Stella C Lymberis
    Department of Radiation Oncology and NYU Cancer Institute, New York University School of Medicine, New York, NY, USA
    Pharmacogenomics 5:31-55. 2004
    ..As a result, pharmacogenomics is rapidly evolving to affect the entire spectrum of breast cancer management, influencing both prevention and treatment choices...
  36. doi request reprint Feasibility of accelerated whole-breast radiation in the treatment of patients with ductal carcinoma in situ of the breast
    Claire Constantine
    Department of Radiation Oncology, New York University School of Medicine, New York, New York 10016, USA
    Clin Breast Cancer 8:269-74. 2008
    ..We report the results of a prospective trial investigating the use of accelerated, hypofractionated whole-breast radiation therapy after breast-conservation surgery for ductal carcinoma in situ (DCIS)...
  37. pmc eIF4GI links nutrient sensing by mTOR to cell proliferation and inhibition of autophagy
    Francisco Ramírez-Valle
    Department of Microbiology, New York University School of Medicine, New York, NY 10016, USA
    J Cell Biol 181:293-307. 2008
    ..These results suggest that the high levels of eIF4GI observed in many breast cancers might act to specifically increase proliferation, prevent autophagy, and release tumor cells from control by nutrient sensing...
  38. doi request reprint Effects of chemoradiation on tumor-host interactions: the immunologic side
    Silvia C Formenti
    J Clin Oncol 26:1562-3; author reply 1563. 2008
  39. ncbi request reprint P7 antigen expression in human breast cancer
    Xiaowei Yang
    Department of Preventive Medicine, University of Southern California School of Medicine, Los Angeles, California 90033, USA
    Clin Cancer Res 9:201-6. 2003
    ..Evaluate p7 expression in human breast cancer and determine whether chemotherapy and radiation therapy effect a change in p7 expression...
  40. ncbi request reprint Results of surgical resection for progression of brain metastases previously treated by gamma knife radiosurgery
    Minh T Truong
    Department of Radiation Oncology, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Neurosurgery 59:86-97; discussion 86-97. 2006
    ....