Adrian Erlebacher

Summary

Affiliation: New York University
Country: USA

Publications

  1. pmc Constraints in antigen presentation severely restrict T cell recognition of the allogeneic fetus
    Adrian Erlebacher
    Department of Pathology, Experimental Pathology Program, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    J Clin Invest 117:1399-411. 2007
  2. pmc Chemokine gene silencing in decidual stromal cells limits T cell access to the maternal-fetal interface
    Patrice Nancy
    Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
    Science 336:1317-21. 2012
  3. pmc Coordinate regulation of tissue macrophage and dendritic cell population dynamics by CSF-1
    Elisa Tagliani
    Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
    J Exp Med 208:1901-16. 2011
  4. pmc Dendritic cell function at the maternal-fetal interface
    Elisa Tagliani
    Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
    Expert Rev Clin Immunol 7:593-602. 2011
  5. pmc Cis-acting pathways selectively enforce the non-immunogenicity of shed placental antigen for maternal CD8 T cells
    Chin Siean Tay
    Department of Pathology, NYU School of Medicine, New York, New York, United States of America
    PLoS ONE 8:e84064. 2013
  6. doi request reprint Mechanisms of T cell tolerance towards the allogeneic fetus
    Adrian Erlebacher
    Department of Pathology and NYU Cancer Institute, NYU School of Medicine, Langone Medical Center, 550 First Avenue, New York, New York 10016, USA
    Nat Rev Immunol 13:23-33. 2013
  7. pmc Acquisition and presentation of follicular dendritic cell-bound antigen by lymph node-resident dendritic cells
    Megan L McCloskey
    Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
    J Exp Med 208:135-48. 2011
  8. doi request reprint Immunology of the maternal-fetal interface
    Adrian Erlebacher
    Department of Pathology and NYU Cancer Institute, NYU School of Medicine, NYU Langone Medical Center, New York, NY 10016, USA
    Annu Rev Immunol 31:387-411. 2013
  9. pmc Immune surveillance of the maternal/fetal interface: controversies and implications
    Adrian Erlebacher
    New York University School of Medicine, New York, NY, USA
    Trends Endocrinol Metab 21:428-34. 2010
  10. pmc Dendritic cell entrapment within the pregnant uterus inhibits immune surveillance of the maternal/fetal interface in mice
    Mary K Collins
    Department of Pathology, New York University School of Medicine, 550 First Avenue, New York, New York, USA
    J Clin Invest 119:2062-73. 2009

Collaborators

Detail Information

Publications13

  1. pmc Constraints in antigen presentation severely restrict T cell recognition of the allogeneic fetus
    Adrian Erlebacher
    Department of Pathology, Experimental Pathology Program, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    J Clin Invest 117:1399-411. 2007
    ..The pronounced degree of T cell ignorance of the fetus also has implications for the pathophysiology of immune-mediated early pregnancy loss...
  2. pmc Chemokine gene silencing in decidual stromal cells limits T cell access to the maternal-fetal interface
    Patrice Nancy
    Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
    Science 336:1317-21. 2012
    ..These findings give insight into mechanisms of fetomaternal immune tolerance, as well as reveal the epigenetic modification of tissue stromal cells as a modality for limiting effector T cell trafficking...
  3. pmc Coordinate regulation of tissue macrophage and dendritic cell population dynamics by CSF-1
    Elisa Tagliani
    Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
    J Exp Med 208:1901-16. 2011
    ..Together, these data provide cellular and molecular insight into the regulation of Mφ tissue densities under noninflammatory conditions and reveal a central role for CSF-1 in the coordination of Mφ and DC homeostasis...
  4. pmc Dendritic cell function at the maternal-fetal interface
    Elisa Tagliani
    Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
    Expert Rev Clin Immunol 7:593-602. 2011
    ..Further research on the biology of uterine DCs promises to give insight into the pathogenesis of many clinically important disorders of pregnancy...
  5. pmc Cis-acting pathways selectively enforce the non-immunogenicity of shed placental antigen for maternal CD8 T cells
    Chin Siean Tay
    Department of Pathology, NYU School of Medicine, New York, New York, United States of America
    PLoS ONE 8:e84064. 2013
    ..Together, these results outline a major pathway governing the maternal immune response to the placenta, and suggest how tolerance to placental antigens can be maintained systemically without being detrimental to host defense. ..
  6. doi request reprint Mechanisms of T cell tolerance towards the allogeneic fetus
    Adrian Erlebacher
    Department of Pathology and NYU Cancer Institute, NYU School of Medicine, Langone Medical Center, 550 First Avenue, New York, New York 10016, USA
    Nat Rev Immunol 13:23-33. 2013
    ..The T cell response to antigens expressed by the conceptus serves as a paradigm for the study of tissue-specific immune tolerance and is relevant to the pathogenesis of immune-mediated pregnancy complications...
  7. pmc Acquisition and presentation of follicular dendritic cell-bound antigen by lymph node-resident dendritic cells
    Megan L McCloskey
    Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
    J Exp Med 208:135-48. 2011
    ..These results significantly broaden the scope of FDC function and suggest new ways that the complement system and persistent antigen presentation might influence T cell activation and the maintenance of peripheral immune tolerance...
  8. doi request reprint Immunology of the maternal-fetal interface
    Adrian Erlebacher
    Department of Pathology and NYU Cancer Institute, NYU School of Medicine, NYU Langone Medical Center, New York, NY 10016, USA
    Annu Rev Immunol 31:387-411. 2013
    ....
  9. pmc Immune surveillance of the maternal/fetal interface: controversies and implications
    Adrian Erlebacher
    New York University School of Medicine, New York, NY, USA
    Trends Endocrinol Metab 21:428-34. 2010
    ....
  10. pmc Dendritic cell entrapment within the pregnant uterus inhibits immune surveillance of the maternal/fetal interface in mice
    Mary K Collins
    Department of Pathology, New York University School of Medicine, 550 First Avenue, New York, New York, USA
    J Clin Invest 119:2062-73. 2009
    ....
  11. pmc miR-30b/30d regulation of GalNAc transferases enhances invasion and immunosuppression during metastasis
    Avital Gaziel-Sovran
    Department of Pathology, New York University Medical Center, NY 10016, USA
    Cancer Cell 20:104-18. 2011
    ..These data support a key role of miR-30b/30d and GalNAc transferases in metastasis, by simultaneously promoting cellular invasion and immunosuppression...
  12. ncbi request reprint Differential transcription of Eomes and T-bet during maturation of mouse uterine natural killer cells
    Chandrakant Tayade
    Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada N1G 2W1
    J Leukoc Biol 78:1347-55. 2005
    ..Thus, Eomes dominance to T-bet discriminates regulation of the uNK cell subset from that observed for peripheral NK cells...
  13. pmc Intrinsic susceptibility of mouse trophoblasts to natural killer cell-mediated attack in vivo
    Adrian Erlebacher
    Department of Immunology and Infectious Diseases, Harvard School of Public Health, and Department of Medicine, Harvard Medical School, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 99:16940-5. 2002
    ..The apparent intrinsic susceptibility of mouse trophoblasts to immune attack strongly suggests that it is instead some property of the pregnant uterus that is of primary importance in preventing rejection of the fetus...