F L Delmonico
Affiliation: New England Organ Bank
- Exchanging kidneys--advances in living-donor transplantationFrancis L Delmonico
Department of Surgery, Harvard Medical School, and the New England Organ Bank, Boston, USA
N Engl J Med 350:1812-4. 2004
- Donor kidney exchangesFrancis L Delmonico
New England Organ Bank, Newton, MA, USA
Am J Transplant 4:1628-34. 2004..Thus, this approach also increases access to deceased donor kidneys for the remaining candidates on the list...
- Direction of the Organ Procurement and Transplantation Network and United Network for Organ Sharing regarding the oversight of live donor transplantation and solicitation for organsF L Delmonico
United Network for Organ Sharing and The Organ Procurement and Transplantation Network
Am J Transplant 6:37-40. 2006....
- The science and social necessity of deceased organ donationFrancis L Delmonico
Professor of Surgery, Harvard Medical School, Boston, USA President elect, The Transplantation Society, Montreal, Canada
Rambam Maimonides Med J 2:e0048. 2011..The social necessity of a scientifically and medically applied system of deceased organ donation is now evident so that a sufficient number of organs can be available for patients from within the country where they reside. ..
- The alternative Iranian model of living renal transplantationFrancis L Delmonico
Department of Surgery, Harvard University, Boston, MA, USA
Kidney Int 82:625-6. 2012..Iran is proceeding with an independent program of deceased organ donation in cities such as Shiraz. Mahdavi-Mazdeh's report is encouraging for the prospect of a revitalized expansion of deceased donation...
- Commentary: the WHO resolution on human organ and tissue transplantationFrancis L Delmonico
Department of Surgery, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA
Transplantation 79:639-40. 2005
- The Pakistani revelationFrancis L Delmonico
Transplantation Unit, Massachusetts General Hospital, 55 Fruit Street, Boston, Massachusetts 02114 2696, USA
Transpl Int 20:924-5. 2007
- Analysis of the wait list and deaths among candidates waiting for a kidney transplantFrancis L Delmonico
Department of Surgery, Transplantation Center, Massachusetts General Hospital, Boston, MA 02114 2696, USA
Transplantation 86:1678-83. 2008..Candidates designated as inactive on the kidney waiting list were examined to determine total length of time with inactive status and total time on the list...
- A Report of the Amsterdam Forum On the Care of the Live Kidney Donor: Data and Medical GuidelinesFrancis Delmonico
The Ethics Committee of the Transplantation Society, The Transplantation Society Central Business Office, 205 Viger Avenue West, Suite 201, Montreal, Quebec H2Z 1G2, Canada
Transplantation 79:S53-66. 2005....
- The implications of Istanbul Declaration on organ trafficking and transplant tourismFrancis L Delmonico
Harvard Medical School, Massachusetts General Hospital, Transplant Center Boston, Boston, Massachusetts 02114 2696, USA
Curr Opin Organ Transplant 14:116-9. 2009..Organ trafficking and transplant tourism should be prohibited because they violate the principles of equity, justice and respect for human dignity...
- The international realities of live donor kidney transplantationFrancis L Delmonico
Department of Surgery, Harvard University, Boston, Massachusetts 02114, USA
Kidney Int 75:1003-5. 2009..Assembling worldwide data on live-donor kidney transplants is a commendable accomplishment that serves the international transplant community well...
- A call for government accountability to achieve national self-sufficiency in organ donation and transplantationFrancis L Delmonico
New England Organ Bank, Waltham, MA 02451, USA
Lancet 378:1414-8. 2011..Each country or region should strive to provide a sufficient number of organs from within its own population, guided by WHO ethics principles...
- What is the system failure?F L Delmonico
Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Kidney Int 69:954-5. 2006..The "system failure" is not only at the doorstep of organ donation. The expansion of the waiting list for kidney transplants is heavily composed of the elderly who could have benefited by preventive medical care...
- KDIGO guideline for the care of kidney transplant recipients will be resource challengedFrancis L Delmonico
Department of Surgery, Massachusetts General Hospital, Harvard University, Cambridge, Massachusetts, USA
Kidney Int 77:271-2. 2010..This guideline will require careful attention for implementation in the context of available resources within each country, especially those with underdeveloped economies...
- Organ donation and utilization in the United States, 2004Francis L Delmonico
Massachusetts General Hospital, Boston, MA, USA
Am J Transplant 5:862-73. 2005..Non-traditional donor sources have experienced a large rate of increase; in 2003 the number of ECD kidney donors increased by 8% and the number of DCD donors increased by 43%, from 189 donors in year 2002 to 271 donors in 2003...
- Control of antidonor antibody production with tacrolimus and mycophenolate mofetil in renal allograft recipients with chronic rejectionT P Theruvath
Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
Transplantation 72:77-83. 2001..Limitation of antidonor antibody synthesis may be important for the treatment or the prevention of chronic rejection in organ transplantation...
- Determinants of discard of expanded criteria donor kidneys: impact of biopsy and machine perfusionR S Sung
Scientific Registry of Transplant Recipients, Division of Transplantation, Department of Surgery, University of Michigan, Ann Arbor, MI, USA
Am J Transplant 8:783-92. 2008..59, p < 0.0001) but not graft failure (RR = 0.9, p = 0.27). Biopsy findings and machine perfusion are important correlates of ECD kidney discard; corresponding associations with graft failure require further study...
- Impact of donor kidney recovery method on lymphatic complications in kidney transplantationR F Saidi
Transplant Center, Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts 02214, USA
Transplant Proc 40:1054-5. 2008..We evaluated the impact of kidney recovery methods (deceased donor vs laparoscopic nephrectomy) on the lymphatic complications of the kidney transplant recipients...
- Why we should not pay for human organsFrancis L Delmonico
Harvard Medical School, Boston, Massachusetts, USA
Natl Cathol Bioeth Q 2:381-9. 2002
- Dynamic challenges inhibiting optimal adoption of kidney paired donation: findings of a consensus conferenceM L Melcher
Department of Surgery, Stanford University, Stanford, CA, USA
Am J Transplant 13:851-60. 2013..Best practices, knowledge gaps and research goals were identified and summarized in this document...
- Ethical incentives--not payment--for organ donationFrancis L Delmonico
Massachusetts General Hospital, Boston, MA 02114, USA
N Engl J Med 346:2002-5. 2002
- The development of a successful multiregional kidney paired donation programRuthanne L Hanto
New England Organ Bank, New England Program for Kidney Exchange, One Gateway Center, Newton, MA, USA
Transplantation 86:1744-8. 2008..Two large regional programs, The New England Program for Kidney Exchange (NEPKE) and the Mid-Atlantic Paired Exchange Program (MAPEP) have developed a system of protocols to effectively increase the number of KPD transplants...
- Increasing the supply of kidneys for transplantationKevin J O'Connor
New England Organ Bank, Newton, Massachusetts 02492, USA
Semin Dial 18:460-2. 2005..Paired live donor kidney transplants provide yet another transplantation opportunity for ESRD patients with willing but incompatible (by ABO or direct antibody) living donors...
- Living donor kidney transplantation in a global environmentF L Delmonico
Harvard Medical School and Massachusetts General Hospital, The Transplantation Society, Boston, Massachusetts, USA
Kidney Int 71:608-14. 2007....
- Utilizing list exchange and nondirected donation through 'chain' paired kidney donationsA E Roth
Harvard University, Department of Economics, Cambridge, Massachusetts and Harvard Business School, Boston, Massachusetts, USA
Am J Transplant 6:2694-705. 2006..We recommend that both LE and ND donations be utilized through chain exchanges...
- The impact of variation in donation after cardiac death policies among donor hospitals: a regional analysisJ Y Rhee
Transplantation, Tufts Medical Center, Boston, MA, USA
Am J Transplant 11:1719-26. 2011..Our regional analysis highlights the high degree of variability of hospital DCD policies, which may contribute to misunderstanding and confusion among providers and patients that may influence acceptance of this mode of donation...
- Impact of the expanded criteria donor allocation system on the use of expanded criteria donor kidneysRandall S Sung
Scientific Registry of Transplant Recipients, Division of Transplantation, Department of Surgery, University of Michigan Health System, Taubman Center, Ann Arbor, MI 48109 0331, USA
Transplantation 79:1257-61. 2005..5 mg/dL, history of hypertension, or death by cerebrovascular accident. The impact of this policy on use of ECD kidneys is assessed...
- Increasing the opportunity of live kidney donation by matching for two- and three-way exchangesSusan L Saidman
Department of Pathology, Massachusetts General Hospital, Boston, MA, USA
Transplantation 81:773-82. 2006....
- The use of a minor as a live kidney donorFrancis L Delmonico
Department of Surgery, Harvard Medical School, Massachusets General Hospital, Boston, USA
Am J Transplant 2:333-6. 2002..Live organ donation from a minor should only be considered when there is no other living donor available and all other opportunities for transplantation have been exhausted...
- Managing the highly sensitized transplant recipient and B cell toleranceS Baid
Renal and Transplantation Units, and Histocompatibility Laboratory, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA
Curr Opin Immunol 13:577-81. 2001..Ultimately, the induction of mixed hematopoietic chimerism may allow us to overcome the problem of allosensitization and accept an allograft without chronic immunosuppression...
- Investigating geographic variation in mortality in the context of organ donationE Sheehy
New England Organ Bank, Waltham, MA, USA
Am J Transplant 12:1598-602. 2012..These deaths are correlated with eligible deaths for organ donation. Regional availability of organs is affected by deaths which should be accounted for in the organ allocation system...
- Outcome of kidney transplantation using expanded criteria donors and donation after cardiac death kidneys: realities and costsR F Saidi
Department of Surgery, Transplantation Unit, Massachusetts General Hospital, Boston, MA, USA
Am J Transplant 7:2769-74. 2007..Revised reimbursement guidelines will be required for centers that utilize these organs...
- Liver transplantation for primary hepatic cancerC E Haug
Department of Surgery, Massachusetts General Hospital, Boston 02114
Transplantation 53:376-82. 1992..These results emphasize that orthotopic liver transplantation can provide a long-term cure for approximately 50% of patients whose primary hepatic malignancy is unresectable by conventional procedures...
- Approach to the management of allograft recipients following the detection of hepatitis B virus in the prospective organ donorR T Chung
Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, USA
Am J Transplant 1:185-91. 2001....
- Is this live-organ donor your patient?Francis L Delmonico
Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA
Transplantation 76:1257-60. 2003..If equipoise is not affirmatively achieved in the risk-benefit calculation for the donor and the recipient, then sound medical judgment should override all other concerns...
- Report of the Crystal City meeting to maximize the use of organs recovered from the cadaver donorBruce R Rosengard
Harvard Medical School, Massachusetts General Hospital, Boston 02114, USA
Am J Transplant 2:701-11. 2002
- A prospective, randomized, clinical trial of intraoperative versus postoperative Thymoglobulin in adult cadaveric renal transplant recipientsWilliam C Goggins
Department of Surgery, Brigham and Women s Hospital, Boston, MA, USA
Transplantation 76:798-802. 2003..Previous retrospective or nonrandomized studies have suggested that intraoperative administration of polyclonal antithymocyte preparations may reduce the incidence of DGF, possibly by decreasing ischemia-reperfusion injury...
- Donation after cardiac death as a strategy to increase deceased donor liver availabilityRobert M Merion
Department of Surgery, University of Michigan Health System, Ann Arbor, MI, USA
Ann Surg 244:555-62. 2006..This study examines donation after cardiac death (DCD) practices and outcomes in liver transplantation...
- Solid organ procurement from burned childrenR L Sheridan
Shriners Burns Hospital, Boston, Massachusetts 02114, USA
J Trauma 47:1060-2. 1999....
- Summary report of a national conference: Evolving concepts in liver allocation in the MELD and PELD era. December 8, 2003, Washington, DC, USAKim M Olthoff
Department of Surgery, Division of Transplantation, University of Pennsylvania, Philadelphia, PA, USA
Liver Transpl 10:A6-22. 2004..Recommendations for the transplant community, based on the analysis of the MELD data, were discussed and are presented in the summary document...
- Morbidity and mortality after living kidney donation, 1999-2001: survey of United States transplant centersArthur J Matas
Department of Surgery, University of Minnesota, Minneapolis, MN, USA
Am J Transplant 3:830-4. 2003..Morbidity and mortality for living donor nephrectomy at transplant centers in the United States remain low. We provide current data from which comprehensive informed consent can be obtained from donors...
- Acute humoral rejection in kidney transplantation: II. Morphology, immunopathology, and pathologic classificationShamila Mauiyyedi
Pathology Service, Immunopathology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
J Am Soc Nephrol 13:779-87. 2002..Because AHR has a distinct therapy and prognosis, we propose that it should be classified separately from ACR, with further sub-classification into AHR 1 (neutrophilic capillary involvement) and AHR 2 (arterial fibrinoid necrosis)...
- The report of a national conference on the wait list for kidney transplantationRobert S Gaston
Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA
Am J Transplant 3:775-85. 2003..Each work group outlined problems and potential remedies within each area. This report summarized the issues and recommendations regarding the waiting list for kidney transplantation addressed in the Philadelphia meeting...
- Induction of kidney allograft tolerance after transient lymphohematopoietic chimerism in patients with multiple myeloma and end-stage renal diseaseLeo H Buhler
Department of Surgery, Massachusetts General Hospital, Boston, MA 02114, USA
Transplantation 74:1405-9. 2002....
- Acute humoral rejection in hepatitis C-infected renal transplant recipients receiving antiviral therapySeema Baid
Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
Am J Transplant 3:74-8. 2003..The recognition of IFN-associated acute humoral rejection in this series may explain the high rate of graft loss reported previously in renal recipients receiving IFN...
- Long-term outcome of a cuffed expanded PTFE graft for hemodialysis vascular accessGeorge Tsoulfas
Department of Surgery, Transplant Center, White 510, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
World J Surg 32:1827-31. 2008..In the present study, we retrospectively analyzed the long-term results of cuffed expanded polytetrafluoroethylene (ePTFE) and non-cuffed (standard) ePTFE grafts placed for hemodialysis access...
- Cardiovascular risk profile after conversion from cyclosporine A to tacrolimus in stable renal transplant recipientsSeema Baid-Agrawal
Renal Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA
Transplantation 77:1199-202. 2004..We investigated overall cardiovascular risk profile after conversion from CsA to TAC...
- Analysis of the cardiovascular risk profile in stable kidney transplant recipients after 50% cyclosporine reductionWaichi Wong
Transplantation Unit, Massachusetts General Hospital and Harvard Medical School, Boston, 02114, USA
Clin Transplant 18:341-8. 2004..Hence, a reduction in CsA dosage in kidney transplant recipients (KTR) may improve long-term outcomes. We analyzed the effects of 50% CsA dose reduction on the CVD risk profile in stable KTR...
- A prospective, randomized clinical trial of cyclosporine reduction in stable patients greater than 12 months after renal transplantationManuel Pascual
Renal and Transplantation Units, Massachusetts General Hospital, Boston, USA
Transplantation 75:1501-5. 2003..Complete CsA withdrawal has been associated with a significant incidence of acute rejection and, in some studies, chronic rejection as well...
- Living kidney donors in need of kidney transplants: a report from the organ procurement and transplantation networkMary D Ellison
United Network for Organ Sharing, Richmond, VA 23225, USA
Transplantation 74:1349-51. 2002..Our aim was to use the Organ Procurement and Transplantation Network (OPTN) database to determine the number of renal waitlist candidates who previously had been living donors...
- Financial incentives for cadaver organ donation: an ethical reappraisalRobert Arnold
Transplantation 73:1361-7. 2002..We suggest that a pilot project be conducted to determine whether this kind of a financial incentive would be acceptable to the public and successful in increasing organ donation...
- Regulated market for organs is unattainableFrancis L Delmonico
Minn Med 91:6. 2008
- The nondirected live-kidney donor: ethical considerations and practice guidelines: A National Conference ReportPatricia L Adams
Wake Forest University School of Medicine, USA
Transplantation 74:582-9. 2002..Other ethical issues such as the use of prisoners as an NDD, compensation for the NDD, media involvement, and communication between the NDD and recipient are discussed...
- Improving institutional fairness to live kidney donors: donor needs must be addressed by safeguarding donation risks and compensating donation costsAnnette Schulz-Baldes
Institute of Biomedical Ethics, Zurich University Centre for Ethics, Zurich, Switzerland
Transpl Int 20:940-6. 2007..They are essential for preserving institutional fairness in the health care of the live kidney donor...
- Living-donor kidney transplantation: a review of the current practices for the live donorConnie L Davis
Department of Medicine, University of Washington, Transplantation Services, Box 356174, 1959 NE Pacific Street, Seattle, WA, 98195, USA
J Am Soc Nephrol 16:2098-110. 2005..These and other medical risks bring additional responsibility in such circumstances to track the unknown consequences of a live-donor nephrectomy...
- Organ donation and utilization in the USAAkinlolu O Ojo
Scientific Registry of Transplant Recipients University of Michigan, Ann Arbor, MI, USA
Am J Transplant 4:27-37. 2004..The kidney is the organ most likely to be discarded after recovery. Over the past decade the discard rate of recovered kidneys has increased from 6% to 11%. Many of these are expanded criteria donor kidneys...
- Expanded criteria donors for kidney transplantationRobert A Metzger
TransLife Florida Hospital Medical Center, Orlando, FL, USA
Am J Transplant 3:114-25. 2003
- Transplantation in the diabetic patient with advanced chronic kidney disease: a task force reportRobert S Gaston
Division of Nephrology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
Am J Kidney Dis 44:529-42. 2004..This report summarizes the deliberations and recommendations of the task force...
- Managing the enlarging waiting listFrancis L Delmonico
Am J Transplant 2:889-90. 2002
- A report of the Vancouver Forum on the care of the live organ donor: lung, liver, pancreas, and intestine data and medical guidelinesMark L Barr
Transplantation 81:1373-85. 2006
- The ethics statement of the Vancouver Forum on the live lung, liver, pancreas, and intestine donorTimothy L Pruett
Stickler Family Professor of Transplantation Surgery, University of Virginia Health System, USA
Transplantation 81:1386-7. 2006
- A report of the Lisbon Conference on the care of the kidney transplant recipientMario Abbud-Filho
Instituto de Urologia e Nefrologia and Medical School FAMERP, Sao Jose do Rio Preto SP, Brazil
Transplantation 83:S1-22. 2007
- Vancouver forum on the live lung, liver, pancreas, and intestine donorFrancis L Delmonico
Transplantation 82:1245. 2006
- Transplant tumor registry: donors with central nervous system tumors1H Myron Kauffman
Research Department, United Network for Organ Sharing, Richmond, Virginia 23225, USA
Transplantation 73:579-82. 2002..Both the size of the candidate waiting list and the number of deaths on the waiting list are progressively increasing because of the donor shortage...
- Transmission of lymphocytic choriomeningitis virus by organ transplantationStaci A Fischer
Rhode Island Hospital and Brown Medical School, Providence, USA
N Engl J Med 354:2235-49. 2006..Each cluster was investigated because diagnostic evaluations were unrevealing, and in each a common donor was recognized...
- Prevalence and significance of anti-HLA and donor-specific antibodies long-term after renal transplantationFrancesca Cardarelli
Clinica Medica e Nefrologia, Universita degli Studi di Parma, Parma, Italy
Transpl Int 18:532-40. 2005..Anti-HLA antibodies were associated with a worse allograft function and in situ evidence of anti-donor humoral alloreactivity. Long-term RTR with an increase in creatinine could be screened for anti-HLA antibodies and C4d in biopsy...
- Assessing organ donation from the dead should not be done by reporting a census of the livingRichard S Luskin
Am J Transplant 3:1185-7. 2003
- The consequences of public policy to buy and sell organs for transplantationJeffrey P Kahn
Center for Bioethics, University of Minnesota, Minneapolis, MN, USA
Am J Transplant 4:178-80. 2004
- National conference to assess antibody-mediated rejection in solid organ transplantationSteven K Takemoto
Dumont Transplant Program and Immunogenetics Center, UCLA School of Medicine, UCLA, Los Angeles, CA, USA
Am J Transplant 4:1033-41. 2004..Immunologic barriers once considered insurmountable are now consistently overcome to enable more patients to undergo organ transplantation...
- When organ donors are still patients: is premortem use of heparin ethically acceptable?James M DuBois
Health Care Ethics, Saint Louis University, St Louis, Missouri 63103, USA
Am J Crit Care 16:396-400. 2007
- Hormonal resuscitation yields more transplanted hearts, with improved early functionJohn D Rosendale
Research Department, United Network for Organ Sharing, Richmond, VA 23219, USA
Transplantation 75:1336-41. 2003..The goal of this study was to examine the quality of hearts recovered from donors treated with hormonal resuscitation...
- Maximizing the success of transplantation with kidneys from older donorsFrancis L Delmonico
N Engl J Med 354:411-3. 2006
- Increased transplanted organs from the use of a standardized donor management protocolJohn D Rosendale
Research Department, United Network for Organ Sharing, Richmond, VA, USA
Am J Transplant 2:761-8. 2002..Use of a structured donor management algorithm results in significant increases in organs procured and organs transplanted without any reduction in the quality of the organs being transplanted...
- Research to practice: a national consensus conferenceRobert A Metzger
TransLife at Florida Hospital Medical Center, Orlando, Fla, USA
Prog Transplant 15:379-84. 2005..To gain consensus on aspects of the process of gaining consent for organ donation that should be mainstream daily practice...
- Aggressive pharmacologic donor management results in more transplanted organsJohn D Rosendale
Research Department, United Network for Organ Sharing, Richmond, VA 23218, USA
Transplantation 75:482-7. 2003..Hormonal resuscitation (HR) has been reported to stabilize and improve cardiac function in brain-dead donors. The goal of this study was to examine the effect of HR on the brain-dead donor on the number of organs transplanted per donor...
- Organ donation and dual advocacyRichard S Luskin
N Engl J Med 358:1297-8. 2008
- Donor characteristics associated with reduced graft survival: an approach to expanding the pool of kidney donorsFriedrich K Port
Scientific Registry of Transplant Recipients, University Renal Research and Education Association URREA, Ann Arbor, MI 48103, USA
Transplantation 74:1281-6. 2002..Availability of cadaveric kidneys for transplantation is far below the growing need, leading to longer waiting time and more deaths while waiting...
- Kidney transplantation as primary therapy for end-stage renal disease: a National Kidney Foundation/Kidney Disease Outcomes Quality Initiative (NKF/KDOQITM) conferenceMichael Abecassis
Division of Nephrology, University of Alabama at Birmingham, 625 THT, 1900 University Boulevard, Birmingham, AL 35294, USA
Clin J Am Soc Nephrol 3:471-80. 2008..5% of incident patients with end-stage renal disease undergo transplantation as their initial modality of treatment, a figure largely unchanged for at least a decade...