JEREMY DASEN

Summary

Affiliation: New York University School of Medicine
Country: USA

Publications

  1. pmc Genetic and functional modularity of Hox activities in the specification of limb-innervating motor neurons
    Julie LaCombe
    Smilow Neuroscience Program, Department of Physiology and Neuroscience, Howard Hughes Medical Institute, NYU School of Medicine, New York, New York, USA
    PLoS Genet 9:e1003184. 2013
  2. pmc Sustained Hox5 gene activity is required for respiratory motor neuron development
    Polyxeni Philippidou
    Howard Hughes Medical Institute, New York University School of Medicine, Smilow Neuroscience Program, Department of Physiology and Neuroscience, New York, New York, USA
    Nat Neurosci 15:1636-44. 2012
  3. ncbi request reprint Long noncoding RNAs in development: solidifying the Lncs to Hox gene regulation
    Jeremy S Dasen
    Howard Hughes Medical Institute, NYU Neuroscience Institute, Department of Neuroscience and Physiology, NYU School of Medicine, New York, NY 10016, USA Electronic address
    Cell Rep 5:1-2. 2013
  4. ncbi request reprint Hox repertoires for motor neuron diversity and connectivity gated by a single accessory factor, FoxP1
    Jeremy S Dasen
    Smilow Neuroscience Program, Department of Physiology and Neuroscience, New York University School of Medicine, New York, NY 10016, USA
    Cell 134:304-16. 2008
  5. pmc Global control of motor neuron topography mediated by the repressive actions of a single hox gene
    Heekyung Jung
    Howard Hughes Medical Institute, Smilow Neuroscience Program, Department of Physiology and Neuroscience, New York University School of Medicine, New York, NY 10016, USA
    Neuron 67:781-96. 2010
  6. ncbi request reprint Motor neuron columnar fate imposed by sequential phases of Hox-c activity
    Jeremy S Dasen
    Howard Hughes Medical Institute, Department of Biochemistry and Molecular Biophysics, Center for Neurobiology and Behavior, Columbia University, 701 West 168th Street, New York, New York 10032, USA
    Nature 425:926-33. 2003
  7. pmc Functional diversity of ESC-derived motor neuron subtypes revealed through intraspinal transplantation
    Mirza Peljto
    Department of Pathology and Cell Biology, Neurology, and Neuroscience, Center for Motor Neuron Biology and Disease, Columbia University Medical Center, New York, NY 10032, USA
    Cell Stem Cell 7:355-66. 2010
  8. ncbi request reprint Hox networks and the origins of motor neuron diversity
    Jeremy S Dasen
    Department of Physiology and Neuroscience, New York University School of Medicine, New York, NY, USA
    Curr Top Dev Biol 88:169-200. 2009
  9. doi request reprint Transcriptional networks in the early development of sensory-motor circuits
    Jeremy S Dasen
    Smilow Neuroscience Program, Department of Physiology, New York University School of Medicine, New York, New York, USA
    Curr Top Dev Biol 87:119-48. 2009
  10. ncbi request reprint Transcriptional mechanisms controlling motor neuron diversity and connectivity
    Simon A Dalla Torre di Sanguinetto
    Biozentrum, Department of Cell Biology, University of Basel, Basel, Switzerland
    Curr Opin Neurobiol 18:36-43. 2008

Collaborators

  • Jeh Ping Liu
  • Michael Rosenfeld
  • Silvia Arber
  • Lucie Jeannotte
  • Bin Wang
  • Polyxeni Philippidou
  • Julie LaCombe
  • Heekyung Jung
  • Jonathan Grinstein
  • Esteban O Mazzoni
  • Hynek Wichterle
  • Mirza Peljto
  • Simon A Dalla Torre di Sanguinetto
  • Lorin E Olson
  • Gülşen Sürmeli
  • Olivia Hanley
  • Carolyn M Walsh
  • Josée Aubin
  • Shaun Mahony
  • Debnath Mukhopadhyay
  • Karel F Liem
  • Richard A Young
  • David K Gifford
  • Kathryn V Anderson
  • Thomas M Jessell
  • Jessica Tollkuhn
  • Bong Gun Ju

Detail Information

Publications12

  1. pmc Genetic and functional modularity of Hox activities in the specification of limb-innervating motor neurons
    Julie LaCombe
    Smilow Neuroscience Program, Department of Physiology and Neuroscience, Howard Hughes Medical Institute, NYU School of Medicine, New York, New York, USA
    PLoS Genet 9:e1003184. 2013
    ....
  2. pmc Sustained Hox5 gene activity is required for respiratory motor neuron development
    Polyxeni Philippidou
    Howard Hughes Medical Institute, New York University School of Medicine, Smilow Neuroscience Program, Department of Physiology and Neuroscience, New York, New York, USA
    Nat Neurosci 15:1636-44. 2012
    ..These findings indicate that Hox5 genes orchestrate PMC development through deployment of temporally distinct wiring programs...
  3. ncbi request reprint Long noncoding RNAs in development: solidifying the Lncs to Hox gene regulation
    Jeremy S Dasen
    Howard Hughes Medical Institute, NYU Neuroscience Institute, Department of Neuroscience and Physiology, NYU School of Medicine, New York, NY 10016, USA Electronic address
    Cell Rep 5:1-2. 2013
    ..In this issue of Cell Reports, Delpretti et al. and Li et al. suggest essential roles for lncRNAs in coordinating Hox gene expression. ..
  4. ncbi request reprint Hox repertoires for motor neuron diversity and connectivity gated by a single accessory factor, FoxP1
    Jeremy S Dasen
    Smilow Neuroscience Program, Department of Physiology and Neuroscience, New York University School of Medicine, New York, NY 10016, USA
    Cell 134:304-16. 2008
    ..Our findings show that FoxP1 is a crucial determinant of motor neuron diversification and connectivity, and clarify how this Hox regulatory network controls the formation of a topographic neural map...
  5. pmc Global control of motor neuron topography mediated by the repressive actions of a single hox gene
    Heekyung Jung
    Howard Hughes Medical Institute, Smilow Neuroscience Program, Department of Physiology and Neuroscience, New York University School of Medicine, New York, NY 10016, USA
    Neuron 67:781-96. 2010
    ..Genome-wide analysis of Hoxc9 binding suggests that this mode of repression is mediated by direct interactions with Hox regulatory elements, independent of chromatin marks typically associated with repressed Hox genes...
  6. ncbi request reprint Motor neuron columnar fate imposed by sequential phases of Hox-c activity
    Jeremy S Dasen
    Howard Hughes Medical Institute, Department of Biochemistry and Molecular Biophysics, Center for Neurobiology and Behavior, Columbia University, 701 West 168th Street, New York, New York 10032, USA
    Nature 425:926-33. 2003
    ..Hox proteins also direct the expression of genes that establish motor topographic projections, thus implicating Hox proteins as critical determinants of spinal motor neuron identity and organization...
  7. pmc Functional diversity of ESC-derived motor neuron subtypes revealed through intraspinal transplantation
    Mirza Peljto
    Department of Pathology and Cell Biology, Neurology, and Neuroscience, Center for Motor Neuron Biology and Disease, Columbia University Medical Center, New York, NY 10032, USA
    Cell Stem Cell 7:355-66. 2010
    ..ESC-derived motor neurons can therefore be programmed in a predictive manner to acquire molecular and functional properties that characterize one of the many dozens of specialized motor neuron subtypes that exist in vivo...
  8. ncbi request reprint Hox networks and the origins of motor neuron diversity
    Jeremy S Dasen
    Department of Physiology and Neuroscience, New York University School of Medicine, New York, NY, USA
    Curr Top Dev Biol 88:169-200. 2009
    ..The emerging logic of Hox protein function in motor neuron specification may provide more general insights into the programs that determine synaptic specificity in other CNS regions...
  9. doi request reprint Transcriptional networks in the early development of sensory-motor circuits
    Jeremy S Dasen
    Smilow Neuroscience Program, Department of Physiology, New York University School of Medicine, New York, New York, USA
    Curr Top Dev Biol 87:119-48. 2009
    ....
  10. ncbi request reprint Transcriptional mechanisms controlling motor neuron diversity and connectivity
    Simon A Dalla Torre di Sanguinetto
    Biozentrum, Department of Cell Biology, University of Basel, Basel, Switzerland
    Curr Opin Neurobiol 18:36-43. 2008
    ..Similar principles using modular interaction of transcriptional programs to control neuronal diversification and circuit connectivity are likely to act in other CNS circuits...
  11. ncbi request reprint A Hox regulatory network establishes motor neuron pool identity and target-muscle connectivity
    Jeremy S Dasen
    Howard Hughes Medical Institute, Department of Biochemistry and Molecular Biophysics, NY 10032, USA
    Cell 123:477-91. 2005
    ..This Hox regulatory network directs the downstream transcriptional identity of motor neuron pools and defines the pattern of target-muscle connectivity...
  12. ncbi request reprint Paired-like repression/activation in pituitary development
    Lorin E Olson
    Howard Hughes Medical Institute, University of California, San Diego, School of Medicine, La Jolla, California 92093 0648, USA
    Recent Prog Horm Res 58:249-61. 2003
    ..The opposing actions of these factors provide one aspect of pituitary organogenesis...

Research Grants2

  1. Transcriptional Control of Motor Neuron Identity and Connectivity
    Jeremy S Dasen; Fiscal Year: 2010
    ..Understanding the steps that determine the intrinsic properties of motor neurons may be essential in designing treatment strategies after spinal cord injury. ..
  2. Transcriptional Control of Motor Neuron Identity and Connectivity
    JEREMY DASEN; Fiscal Year: 2009
    ..Understanding the steps that determine the intrinsic properties of motor neurons may be essential in designing treatment strategies after spinal cord injury. ..