Farbod Darvishian

Summary

Affiliation: New York University School of Medicine
Country: USA

Publications

  1. pmc Assessing the clinical utility of measuring Insulin-like Growth Factor Binding Proteins in tissues and sera of melanoma patients
    Jessie Z Yu
    Department of Dermatology, New York University School of Medicine, New York, NY, USA
    J Transl Med 6:70. 2008
  2. ncbi request reprint Atypia on breast core needle biopsies: reproducibility and significance
    Farbod Darvishian
    Department of Pathology, New York University Medical Center, 530 First Avenue SK7N, New York, NY 10016, USA
    Ann Clin Lab Sci 39:270-6. 2009
  3. pmc Histology-specific microRNA alterations in melanoma
    Laura Poliseno
    The Ronald O Perelman Department of Dermatology, New York University School of Medicine, New York, New York, USA
    J Invest Dermatol 132:1860-8. 2012
  4. pmc Mitotic rate in melanoma: prognostic value of immunostaining and computer-assisted image analysis
    Christopher S Hale
    Department of Pathology, New York University Cancer Institute, New York University School of Medicine, New York, NY 10016, USA
    Am J Surg Pathol 37:882-9. 2013
  5. pmc Clinical variables and primary tumor characteristics predictive of the development of melanoma brain metastases and post-brain metastases survival
    Jan Zakrzewski
    The New York University Interdisciplinary Melanoma Cooperative Group, New York University School of Medicine and New York University Cancer Institute, New York, New York, USA
    Cancer 117:1711-20. 2011
  6. pmc Challenging the current paradigm of melanoma progression: brain metastasis as isolated first visceral site
    Michelle W Ma
    Ronald O Perelman Department of Dermatology, New York University School of Medicine, New York, NY 10016, USA
    Neuro Oncol 14:849-58. 2012
  7. pmc Immune response in melanoma: an in-depth analysis of the primary tumor and corresponding sentinel lymph node
    Michelle W Ma
    Ronald O Perelman Department of Dermatology, New York University School of Medicine, New York, NY, USA
    Mod Pathol 25:1000-10. 2012
  8. pmc Clinical relevance of detection of lymphovascular invasion in primary melanoma using endothelial markers D2-40 and CD34
    Amy E Rose
    Department of Dermatology, New York University School of Medicine, New York, NY, USA
    Am J Surg Pathol 35:1441-9. 2011
  9. pmc A high proliferative index of recurrent melanoma is associated with worse survival
    Ting J Tu
    The New York University Interdisciplinary Melanoma Cooperative Group, New York University School of Medicine, New York, NY 10016, USA
    Oncology 80:181-7. 2011
  10. doi request reprint Single versus multiple primary melanomas: old questions and new answers
    Charlotte Hwa
    Ronald O Perelman Department of Dermatology, New York University School of Medicine, New York, New York, USA
    Cancer 118:4184-92. 2012

Collaborators

Detail Information

Publications32

  1. pmc Assessing the clinical utility of measuring Insulin-like Growth Factor Binding Proteins in tissues and sera of melanoma patients
    Jessie Z Yu
    Department of Dermatology, New York University School of Medicine, New York, NY, USA
    J Transl Med 6:70. 2008
    ..In this study, we examined both IGFBP-3 and -4 levels in tissues and sera of melanoma patients representing different stages of melanoma progression...
  2. ncbi request reprint Atypia on breast core needle biopsies: reproducibility and significance
    Farbod Darvishian
    Department of Pathology, New York University Medical Center, 530 First Avenue SK7N, New York, NY 10016, USA
    Ann Clin Lab Sci 39:270-6. 2009
    ..Strict adherence to the diagnostic criteria and tutorial sessions can help pathologists to achieve substantial agreement in interpreting atypia on breast core needle biopsies...
  3. pmc Histology-specific microRNA alterations in melanoma
    Laura Poliseno
    The Ronald O Perelman Department of Dermatology, New York University School of Medicine, New York, New York, USA
    J Invest Dermatol 132:1860-8. 2012
    ..Our data support a molecular classification in which SSM and NM are two molecularly distinct phenotypes. Therapeutic strategies that take into account subtype-specific alterations might improve the outcome of melanoma patients...
  4. pmc Mitotic rate in melanoma: prognostic value of immunostaining and computer-assisted image analysis
    Christopher S Hale
    Department of Pathology, New York University Cancer Institute, New York University School of Medicine, New York, NY 10016, USA
    Am J Surg Pathol 37:882-9. 2013
    ..02). Regardless of the detection method, neither MPM-2 nor PHH3 offered significant advantage over conventional H&E determination of mitotic rate...
  5. pmc Clinical variables and primary tumor characteristics predictive of the development of melanoma brain metastases and post-brain metastases survival
    Jan Zakrzewski
    The New York University Interdisciplinary Melanoma Cooperative Group, New York University School of Medicine and New York University Cancer Institute, New York, New York, USA
    Cancer 117:1711-20. 2011
    ..In the current study, the authors attempted to identify primary tumor characteristics and clinical features predictive of B-Met development and post-B-Met survival...
  6. pmc Challenging the current paradigm of melanoma progression: brain metastasis as isolated first visceral site
    Michelle W Ma
    Ronald O Perelman Department of Dermatology, New York University School of Medicine, New York, NY 10016, USA
    Neuro Oncol 14:849-58. 2012
    ..Studies are needed to better understand the biological factors driving this phenotype at the time of primary melanoma diagnosis and to determine its clinical implications...
  7. pmc Immune response in melanoma: an in-depth analysis of the primary tumor and corresponding sentinel lymph node
    Michelle W Ma
    Ronald O Perelman Department of Dermatology, New York University School of Medicine, New York, NY, USA
    Mod Pathol 25:1000-10. 2012
    ..025) and melanoma-specific (P=0.014) survival. Our results support an assessment of local immune profiles in both the primary tumor and sentinel lymph node to help guide therapeutic decisions...
  8. pmc Clinical relevance of detection of lymphovascular invasion in primary melanoma using endothelial markers D2-40 and CD34
    Amy E Rose
    Department of Dermatology, New York University School of Medicine, New York, NY, USA
    Am J Surg Pathol 35:1441-9. 2011
    ..27-3.18; P=0.003] and OS (HR, 2.08; 95% CI: 1.25-3.46; P=0.005). Results show that D2-40 and CD34 increase the detection of LVI in primary melanoma and that cases missed by routine histology have prognostic relevance...
  9. pmc A high proliferative index of recurrent melanoma is associated with worse survival
    Ting J Tu
    The New York University Interdisciplinary Melanoma Cooperative Group, New York University School of Medicine, New York, NY 10016, USA
    Oncology 80:181-7. 2011
    ..We examined the prognostic relevance of recurrent tumor proliferation...
  10. doi request reprint Single versus multiple primary melanomas: old questions and new answers
    Charlotte Hwa
    Ronald O Perelman Department of Dermatology, New York University School of Medicine, New York, New York, USA
    Cancer 118:4184-92. 2012
    ....
  11. pmc Integrative genomics identifies molecular alterations that challenge the linear model of melanoma progression
    Amy E Rose
    Department of Dermatology, New York University School of Medicine, New York, New York, USA
    Cancer Res 71:2561-71. 2011
    ..Furthermore, our data suggest a role for altered regulation of metabolism-related genes as a possible cause of the different clinical behavior of SSM and NM...
  12. pmc Clinical relevance of SKP2 alterations in metastatic melanoma
    Amy E Rose
    Ronald O Perelman Department of Dermatology, New York University School of Medicine, New York, NY, USA
    Pigment Cell Melanoma Res 24:197-206. 2011
    ..Copy number gain is a major contributing mechanism of SKP2 overexpression in metastatic melanoma. Results may have implications for the development of therapeutics that target SKP2...
  13. doi request reprint Melanoma MicroRNA signature predicts post-recurrence survival
    Miguel F Segura
    Department of Pathology, New York University School of Medicine, New York, New York, USA
    Clin Cancer Res 16:1577-86. 2010
    ..To identify a melanoma microRNA (miRNA) expression signature that is predictive of outcome and then evaluate its potential to improve risk stratification when added to the standard-of-care staging criteria...
  14. pmc Immune profile and mitotic index of metastatic melanoma lesions enhance clinical staging in predicting patient survival
    Dusan Bogunovic
    Cancer Institute and Department of Pathology, New York University Langone Medical Center, New York, NY 10016, USA
    Proc Natl Acad Sci U S A 106:20429-34. 2009
    ....
  15. pmc Impact of age on the management of primary melanoma patients
    Nathaniel H Fleming
    Interdisciplinary Melanoma Cooperative Group, New York University School of Medicine, New York, N Y, USA
    Oncology 85:173-81. 2013
    ..Age is an understudied factor when considering treatment options for melanoma. Here, we examine the impact of age on primary melanoma treatment in a prospective cohort of patients...
  16. pmc The novel gamma secretase inhibitor RO4929097 reduces the tumor initiating potential of melanoma
    Chanh Huynh
    Department of Medicine, New York University School of Medicine, New York, New York, United States of America
    PLoS ONE 6:e25264. 2011
    ..Finally, increased gene expression of NOTCH signaling components correlated with shorter post recurrence survival in metastatic melanoma cases. Our data support NOTCH inhibition as a promising therapeutic strategy against melanoma...
  17. pmc Intra- and inter-tumor heterogeneity of BRAF(V600E))mutations in primary and metastatic melanoma
    Molly Yancovitz
    Department of Dermatology, New York University Langone Medical Center, New York, New York, United States of America
    PLoS ONE 7:e29336. 2012
    ....
  18. pmc miR-30b/30d regulation of GalNAc transferases enhances invasion and immunosuppression during metastasis
    Avital Gaziel-Sovran
    Department of Pathology, New York University Medical Center, NY 10016, USA
    Cancer Cell 20:104-18. 2011
    ..These data support a key role of miR-30b/30d and GalNAc transferases in metastasis, by simultaneously promoting cellular invasion and immunosuppression...
  19. doi request reprint Microinvasive breast cancer and the role of sentinel node biopsy: an institutional experience and review of the literature
    Amber A Guth
    Department of Surgery, NYU School of Medicine, New York City, New York, USA
    Breast J 14:335-9. 2008
    ..In this series, 7% of patients had macrometastatic disease, and two patients (5%) had itc only. Axillary staging is indicated, and SNB is appropriate for the identification of axillary metastatic disease...
  20. doi request reprint Is surgical excision necessary for the management of atypical lobular hyperplasia and lobular carcinoma in situ diagnosed on core needle biopsy?: a report of 38 cases and review of the literature
    Joan Cangiarella
    Department of Pathology, New York University School of Medicine, New York, USA
    Arch Pathol Lab Med 132:979-83. 2008
    ..Due to the debate over the significance of these lesions and the small number of cases reported in the literature, the treatment for lobular neoplasia diagnosed by percutaneous core biopsy (PCB) remains controversial...
  21. pmc T-cell receptor affinity and avidity defines antitumor response and autoimmunity in T-cell immunotherapy
    Shi Zhong
    New York University Cancer Institute, New York University School of Medicine, New York, NY 10016, USA
    Proc Natl Acad Sci U S A 110:6973-8. 2013
    ..The low threshold, in turn, indicates that adoptive T-cell therapy treatment strategies using in vitro-generated high-affinity TCRs do not necessarily improve efficacy...
  22. doi request reprint Essential role for eIF4GI overexpression in the pathogenesis of inflammatory breast cancer
    Deborah Silvera
    Department of Microbiology, New York University School of Medicine, New York, 10016, USA
    Nat Cell Biol 11:903-8. 2009
    ..Overexpression of eIF4GI promotes formation of IBC tumour emboli by enhancing translation of IRES-containing p120 mRNAs. These findings provide a new understanding of translational control in the development of advanced breast cancer...
  23. doi request reprint Chromophobe renal cell carcinoma: a clinicopathologic study of 203 tumors in 200 patients with primary resection at a single institution
    Christopher G Przybycin
    Department of Pathology, Urology Service, Memorial Sloan Kettering Cancer Center New York, NY 10065, USA
    Am J Surg Pathol 35:962-70. 2011
    ..On the basis of this long follow-up on a large number of cases, chromophobes seem to have better clinical outcomes than those reported for clear cell and papillary RCCs...
  24. pmc Changes in the presentation of nodular and superficial spreading melanomas over 35 years
    Melanie A Warycha
    Department of Dermatology, New York University School of Medicine, New York, NY 10016, USA
    Cancer 113:3341-8. 2008
    ..To better define the clinical behavior of NMs, the authors compared their clinical and histopathologic features to those of SSMs at their institution, a tertiary referral center, over 3 decades...
  25. ncbi request reprint Intraparenchymal leiomyoma of the breast: a case report and review of the literature
    Lauren Ende
    Dept of Pathology, NYU School of Medicine, New York, NY 10016, USA
    Ann Clin Lab Sci 37:268-73. 2007
    ..In addition, we review the literature on this uncommon breast neoplasm...
  26. ncbi request reprint Invasive lobular carcinoma of the breast: role of endothelial lymphatic marker D2-40
    Jordan Laser
    New York University School of Medicine, New York, NY 10016, USA
    Ann Clin Lab Sci 38:99-104. 2008
    ..In conclusion, D2-40 antibody staining may be useful as an adjunct in detecting LVI in invasive lobular carcinoma, especially in node-negative patients with the classic variant of invasive lobular carcinoma...
  27. ncbi request reprint Myoepithelial cell-rich neoplasms: cytologic features of benign and malignant lesions
    Farbod Darvishian
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Cancer 102:355-61. 2004
    ..The authors characterized the cytologic features of myoepithelial cell-rich lesions in an attempt to define the criteria that facilitate distinction between benign and malignant tumors...
  28. pmc Association of MDM2 SNP309, age of onset, and gender in cutaneous melanoma
    Elnaz F Firoz
    Department of Dermatology, New York University School of Medicine, New York, New York, USA
    Clin Cancer Res 15:2573-80. 2009
    ..To investigate this difference, we examined the association among MDM2 SNP309, age at diagnosis, and gender among melanoma patients...
  29. ncbi request reprint Serous endometrial cancers that mimic endometrioid adenocarcinomas: a clinicopathologic and immunohistochemical study of a group of problematic cases
    Farbod Darvishian
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Am J Surg Pathol 28:1568-78. 2004
    ..We sought an immunohistochemical panel to minimize subjectivity in the distinction of USC from EEC...
  30. ncbi request reprint Immunoreactivity of p16 in anal cytology specimens: histologic correlation
    Farbod Darvishian
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Cancer 108:66-71. 2006
    ..Due to potential diagnostic pitfalls in anal cytology, p16 overexpression in these specimens was studied...
  31. ncbi request reprint Extramedullary hematopoiesis in breast after neoadjuvant chemotherapy for breast carcinoma
    Jun Wang
    Department of Pathology, New York University Medical Center, New York, NY 10016, USA
    Ann Clin Lab Sci 36:475-8. 2006
    ..To our knowledge, the association of EMH and neoadjuvant chemotherapy has not been previously reported...
  32. ncbi request reprint Carcinosarcoma of the pancreas: a case report and review of the literature
    Farbod Darvishian
    Department of Pathology, North Shore University Hospital, Manhasset, NY 11030, USA
    Arch Pathol Lab Med 126:1114-7. 2002
    ..To our knowledge, this carcinosarcoma is the seventh reported case of a primary pancreatic neoplasm with mixed carcinomatous and sarcomatous elements...