Maria A Curotto de Lafaille

Summary

Affiliation: New York University
Country: USA

Publications

  1. doi request reprint Adaptive Foxp3+ regulatory T cell-dependent and -independent control of allergic inflammation
    Maria A Curotto de Lafaille
    Program of Molecular Pathogenesis, The Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, NY 10016, USA
    Immunity 29:114-26. 2008
  2. ncbi request reprint CD4(+) regulatory T cells in autoimmunity and allergy
    Maria A Curotto de Lafaille
    Program of Molecular Pathogenesis, Skirball Institute of Biomolecular Medicine, and Department of Pathology New York University School of Medicine, New York, NY 10016, USA
    Curr Opin Immunol 14:771-8. 2002
  3. ncbi request reprint The role of regulatory T cells in allergy
    Maria A Curotto de Lafaille
    Program of Molecular Pathogenesis, Skirball Institute of Biomolecular Medicine and Department of Pathology, New York University School of Medicine, NY 10016, USA
    Springer Semin Immunopathol 25:295-310. 2004
  4. ncbi request reprint CD25- T cells generate CD25+Foxp3+ regulatory T cells by peripheral expansion
    Maria A Curotto de Lafaille
    Molecular Pathogenesis Program, Skirball Institute, and Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
    J Immunol 173:7259-68. 2004
  5. pmc Control of homeostatic proliferation by regulatory T cells
    Shiqian Shen
    Molecular Pathogenesis Program, Skirball Institute for Biomolecular Medicine, New York University School of Medicine, New York, New York 10016, USA
    J Clin Invest 115:3517-26. 2005
  6. pmc Diesel exhaust particle-exposed human bronchial epithelial cells induce dendritic cell maturation and polarization via thymic stromal lymphopoietin
    Bertram Bleck
    Department of Medicine, Division of Pulmonary and Critical Care Medicine, New York University School of Medicine, 550 1st Avenue, Room NB7N24, New York, NY, USA
    J Clin Immunol 28:147-56. 2008
  7. pmc Unique maturation program of the IgE response in vivo
    Agustin Erazo
    Program of Molecular Pathogenesis, Skirball Institute of Biomolecular Medicine, New York University School of Medicine, New York, NY 10016, USA
    Immunity 26:191-203. 2007
  8. pmc Oral tolerance in the absence of naturally occurring Tregs
    Daniel Mucida
    Program of Molecular Pathogenesis, Skirball Institute of Biomolecular Medicine, New York University School of Medicine, New York, NY 10016, USA
    J Clin Invest 115:1923-33. 2005
  9. pmc Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells
    Jonathan M Weiss
    Kimmel Center for Biology and Medicine at the Skirball Institute, New York University School of Medicine, New York, NY 10016, USA
    J Exp Med 209:1723-42, S1. 2012
  10. doi request reprint What is unique about the IgE response?
    Huizhong Xiong
    Kimmel Center for Biology and Medicine at the Skirball Institute, New York University School of Medicine, New York, USA
    Adv Immunol 116:113-41. 2012

Collaborators

Detail Information

Publications20

  1. doi request reprint Adaptive Foxp3+ regulatory T cell-dependent and -independent control of allergic inflammation
    Maria A Curotto de Lafaille
    Program of Molecular Pathogenesis, The Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, New York, NY 10016, USA
    Immunity 29:114-26. 2008
    ..Thus, whereas adaptive Foxp3(+) Treg cells regulate sensitization to allergens and the severity of chronic inflammation, IFN-gamma-producing cells can play a beneficial role in inflammatory conditions involving eosinophils...
  2. ncbi request reprint CD4(+) regulatory T cells in autoimmunity and allergy
    Maria A Curotto de Lafaille
    Program of Molecular Pathogenesis, Skirball Institute of Biomolecular Medicine, and Department of Pathology New York University School of Medicine, New York, NY 10016, USA
    Curr Opin Immunol 14:771-8. 2002
    ....
  3. ncbi request reprint The role of regulatory T cells in allergy
    Maria A Curotto de Lafaille
    Program of Molecular Pathogenesis, Skirball Institute of Biomolecular Medicine and Department of Pathology, New York University School of Medicine, NY 10016, USA
    Springer Semin Immunopathol 25:295-310. 2004
    ..This article reviews the recent progress on thymic-derived as well as peripherally induced regulatory T cells as they relate to atopy. The latter discussion also includes regulatory T cells that arise through immunotherapy...
  4. ncbi request reprint CD25- T cells generate CD25+Foxp3+ regulatory T cells by peripheral expansion
    Maria A Curotto de Lafaille
    Molecular Pathogenesis Program, Skirball Institute, and Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
    J Immunol 173:7259-68. 2004
    ..The maintenance of CD25 expression by CD4(+)CD25(+) cells depends on IL-2 secreted by cotransferred CD4(+)CD25(-) or by Ag-stimulated T cells in peripheral lymphoid organs...
  5. pmc Control of homeostatic proliferation by regulatory T cells
    Shiqian Shen
    Molecular Pathogenesis Program, Skirball Institute for Biomolecular Medicine, New York University School of Medicine, New York, New York 10016, USA
    J Clin Invest 115:3517-26. 2005
    ..The presence of Tregs resulted in a lower accumulation of T cells, enhanced apoptosis, and impaired differentiation to a cytokine-producing state. We conclude that Tregs play a major role in the control of homeostatic proliferation...
  6. pmc Diesel exhaust particle-exposed human bronchial epithelial cells induce dendritic cell maturation and polarization via thymic stromal lymphopoietin
    Bertram Bleck
    Department of Medicine, Division of Pulmonary and Critical Care Medicine, New York University School of Medicine, 550 1st Avenue, Room NB7N24, New York, NY, USA
    J Clin Immunol 28:147-56. 2008
    ..These findings provide new insight into the mechanisms by which diesel exhaust particles modify human lung mucosal immunity...
  7. pmc Unique maturation program of the IgE response in vivo
    Agustin Erazo
    Program of Molecular Pathogenesis, Skirball Institute of Biomolecular Medicine, New York University School of Medicine, New York, NY 10016, USA
    Immunity 26:191-203. 2007
    ..Our results have implications for the understanding of IgE memory responses in allergy...
  8. pmc Oral tolerance in the absence of naturally occurring Tregs
    Daniel Mucida
    Program of Molecular Pathogenesis, Skirball Institute of Biomolecular Medicine, New York University School of Medicine, New York, NY 10016, USA
    J Clin Invest 115:1923-33. 2005
    ..However, unlike oral administration of antigen, which induced Tregs but not effector T cells, i.p. immunization led to the simultaneous induction of Tregs and effector Th2 cells displaying the same antigen specificity...
  9. pmc Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells
    Jonathan M Weiss
    Kimmel Center for Biology and Medicine at the Skirball Institute, New York University School of Medicine, New York, NY 10016, USA
    J Exp Med 209:1723-42, S1. 2012
    ..In the same animals, iT reg cells in secondary lymphoid organs remain Nrp1(low). We also determined that, in spontaneous EAE, iT reg cells help to establish a chronic phase of the disease...
  10. doi request reprint What is unique about the IgE response?
    Huizhong Xiong
    Kimmel Center for Biology and Medicine at the Skirball Institute, New York University School of Medicine, New York, USA
    Adv Immunol 116:113-41. 2012
    ....
  11. doi request reprint Natural and adaptive foxp3+ regulatory T cells: more of the same or a division of labor?
    Maria A Curotto de Lafaille
    Molecular Pathogenesis Program, Kimmel Center for Biology and Medicine of the Skirball Institute, and Department of Pathology, New York University School of Medicine, 540 First Avenue, New York, NY 10016, USA
    Immunity 30:626-35. 2009
    ....
  12. pmc Interleukin 2 signaling is required for CD4(+) regulatory T cell function
    Glaucia C Furtado
    Program of Molecular Pathogenesis, Skirball Institute for Biomolecular Medicine, New York University School of Medicine, New York, NY 10016, USA
    J Exp Med 196:851-7. 2002
    ..However, IL-2 signaling in regulatory T cells is essential for their protective function. Altogether, our results favor a model whereby IL-2 induces regulatory T cell activity...
  13. doi request reprint Beta-catenin stabilization extends regulatory T cell survival and induces anergy in nonregulatory T cells
    Yi Ding
    Molecular Pathogenesis Program and Skirball Institute for Biomolecular Medicine, New York University School of Medicine, 540 First Avenue, New York, New York 10016, USA
    Nat Med 14:162-9. 2008
    ..Thus, through enhanced survival of existing regulatory T cells, and through induction of unresponsiveness in precursors of T effector cells, beta-catenin stabilization has a powerful effect on the prevention of inflammatory disease...
  14. pmc Immune regulatory mechanisms influence early pathology in spinal cord injury and in spontaneous autoimmune encephalomyelitis
    Maria Cecilia G Marcondes
    Program of Molecular Pathogenesis, Skirball Institute for Biomolecular Medicine, New York University School of Medicine, New York, USA
    Am J Pathol 166:1749-60. 2005
    ..Overall, our results suggest that common mechanisms regulate T-cell accumulation in CNS lesions of different causes, such as mechanic lesion or autoimmune-mediated damage...
  15. pmc Sequential class switching is required for the generation of high affinity IgE antibodies
    Huizhong Xiong
    Skirball Institute of Biomolecular Medicine, The Sackler Institute of Graduate Biomedical Sciences, New York University School of Medicine, New York, NY 10016, USA
    J Exp Med 209:353-64. 2012
    ..We demonstrate that a small amount of high affinity IgE can cause anaphylaxis and is pathogenic. Low affinity IgE competes with high affinity IgE for binding to Fcε receptors and prevents anaphylaxis and is thus beneficial...
  16. ncbi request reprint Do regulatory T cells play a role in the control of homeostatic proliferation?
    Maria A Curotto de Lafaille
    Molecular Pathogenesis Progam, Skirball Institute of Biomolecular Medicine, and Department of Pathology, New York University School of Medicine, New York 10016, USA
    Int Rev Immunol 24:269-84. 2005
    ..One of these relates to the stage at which regulatory T cells could play a role (i.e., T-cell proliferation vs. survival)...
  17. pmc Acquisition and presentation of follicular dendritic cell-bound antigen by lymph node-resident dendritic cells
    Megan L McCloskey
    Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
    J Exp Med 208:135-48. 2011
    ..These results significantly broaden the scope of FDC function and suggest new ways that the complement system and persistent antigen presentation might influence T cell activation and the maintenance of peripheral immune tolerance...
  18. ncbi request reprint Diesel exhaust particle-exposed human bronchial epithelial cells induce dendritic cell maturation
    Bertram Bleck
    Division of Pulmonary and Critical Care Medicine, New York University School of Medicine, NY 10016, USA
    J Immunol 176:7431-7. 2006
    ..Although additional signals may be required for polarization of DC, these data suggest a novel mechanism by which environmental pollutants alter airway immune responses...
  19. ncbi request reprint The B cell SH2/PH domain-containing adaptor Bam32/DAPP1 is required for T cell-independent II antigen responses
    Emanuel Fournier
    Department of Pharmacology, Skirball Institute of Biomolecular Medicine, New York University School of Medicine, New York 10016, USA
    Curr Biol 13:1858-66. 2003
    ..Bam32/DAPP1 is a B cell adaptor composed of both a PH and an SH2 domain. Previous studies in cell culture and chicken DT40 cells have indicated that Bam32 is critical for normal signaling downstream of the B cell receptor (BCR)...
  20. ncbi request reprint IL-4-secreting CD4+ T cells are crucial to the development of CD8+ T-cell responses against malaria liver stages
    Luzia H Carvalho
    Department of Medical and Molecular Parasitology, New York University School of Medicine, New York, New York, USA
    Nat Med 8:166-70. 2002
    ..This is the first demonstration that IL-4 is a mediator of CD4/CD8 cross-talk leading to the development of immunity against an infectious pathogen...