Oak Z Chi
Affiliation: New Jersey
Chi O, Hunter C, Liu X, Weiss H. Effects of anti-VEGF antibody on blood-brain barrier disruption in focal cerebral ischemia. Exp Neurol. 2007;204:283-7 pubmed
Chi O, Hunter C, Liu X, Chokshi S, Weiss H. Effects of fentanyl pretreatment on regional cerebral blood flow in focal cerebral ischemia in rats. Pharmacology. 2010;85:153-7 pubmed publisher
Chi O, Hunter C, Liu X, Weiss H. Effects of erythropoietin on blood-brain barrier disruption in focal cerebral ischemia. Pharmacology. 2008;82:38-42 pubmed publisher
..003) than that of the control animals. Our data suggest that MCA occlusion increased BBB disruption, and the disruption was attenuated with EPO pretreatment. ..
Chi O, Hunter C, Liu X, Weiss H. Effects of exogenous excitatory amino acid neurotransmitters on blood-brain barrier disruption in focal cerebral ischemia. Neurochem Res. 2009;34:1249-54 pubmed publisher
..Any insult increasing the release of excitatory neurotransmitters could further aggravate BBB disruption and brain edema during the ischemic period. ..
Chi O, Liu X, Weiss H. Effects of mild hypothermia on blood-brain barrier disruption during isoflurane or pentobarbital anesthesia. Anesthesiology. 2001;95:933-8 pubmed
Chi O, Barsoum S, Wen Y, Liu X, Weiss H. 17beta-estradiol prevents blood-brain barrier disruption induced by VEGF. Horm Metab Res. 2004;36:272-6 pubmed
..05). In conclusion, our study demonstrated that chronic 17beta-estradiol treatment prevented BBB disruption induced by the VEGF in the ovariectomized rats. ..
Chi O, Hunter C, Liu X, Tan T, Weiss H. Effects of VEGF on the blood-brain barrier disruption caused by hyperosmolarity. Pharmacology. 2008;82:187-92 pubmed publisher
..However, upregulation of VEGF with CPX did not alter the degree of hyperosmolar BBB disruption with or without anti-VEGF antibody treatment. This study suggests that the contribution of VEGF in hyperosmolar BBB disruption is limited...
Chi O, Hunter C, Liu X, Weiss H. The effects of isoflurane pretreatment on cerebral blood flow, capillary permeability, and oxygen consumption in focal cerebral ischemia in rats. Anesth Analg. 2010;110:1412-8 pubmed publisher
..Because inducible nitric oxide synthase (iNOS) was implicated as one of the mechanisms of isoflurane preconditioning, the effect of iNOS inhibition on rCBF was also studied...