Research Topics
Genomes and Genes
| Yu ChenSummaryAffiliation: New York University School of Medicine Country: USA Publications
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Publications
Arsenic exposure from drinking water and QT-interval prolongation: results from the health effects of arsenic longitudinal studyYu Chen
Department of Population Health, New York University School of Medicine, New York University, New York, New York 10016 USA
Environ Health Perspect 121:427-32, 432e1-7. 2013..Arsenic exposure from drinking water has been associated with heart disease; however, underlying mechanisms are uncertain...- Association between gastric Helicobacter pylori colonization and glycated hemoglobin levelsYu Chen
Department of Environmental Medicine, New York University School of Medicine, New York, NY, USA
J Infect Dis 205:1195-202. 2012..Few studies have evaluated the potential influence of Helicobacter pylori on biomarkers for diabetes... - Association between arsenic exposure from drinking water and proteinuria: results from the Health Effects of Arsenic Longitudinal StudyYu Chen
Department of Environmental Medicine, New York University School of Medicine, New York, NY, USA
Int J Epidemiol 40:828-35. 2011..Proteinuria has been recognized as a marker for an increased risk of chronic renal disease. It is unclear whether arsenic (As) exposure from drinking water is associated with proteinuria... 
Endogenous hormones and coronary heart disease in postmenopausal womenYu Chen
Division of Epidemiology, Department of Environmental Medicine, New York University School of Medicine, New York, NY 10016 3240, United States
Atherosclerosis 216:414-9. 2011..These findings suggest that circulating estradiol and SHBG are not associated with CHD risk in postmenopausal women beyond what can be explained by the variation in hypertension status, BMI, and cholesterol...- Arsenic exposure at low-to-moderate levels and skin lesions, arsenic metabolism, neurological functions, and biomarkers for respiratory and cardiovascular diseases: review of recent findings from the Health Effects of Arsenic Longitudinal Study (HEALS) inYu Chen
Departments of Environmental Medicine and Medicine and New York University Cancer Institute, New York University School of Medicine, New York, NY, USA
Toxicol Appl Pharmacol 239:184-92. 2009.... - Association between arsenic exposure from drinking water and plasma levels of cardiovascular markersFen Wu
Department of Environmental Medicine, New York University School of Medicine, New York, USA
Am J Epidemiol 175:1252-61. 2012.... 
Arsenic exposure from drinking water, dietary intakes of B vitamins and folate, and risk of high blood pressure in Bangladesh: a population-based, cross-sectional studyYu Chen
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA
Am J Epidemiol 165:541-52. 2007..Future research is needed to evaluate the effect of low-level arsenic exposure on specific cardiovascular outcomes...- Consumption of folate-related nutrients and metabolism of arsenic in BangladeshJulia E Heck
Department of Epidemiology, Mailman School of Public Health and Institute for Social and Economic Research and Policy, Columbia University, New York, NY, USA
Am J Clin Nutr 85:1367-74. 2007..Previous studies suggest that persons with more complete methylation, characterized as greater proportions of DMA and lesser proportions of MMA and InAs in urine, have a lower risk of adverse arsenic-related health outcomes... - A prospective study of blood selenium levels and the risk of arsenic-related premalignant skin lesionsYu Chen
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA
Cancer Epidemiol Biomarkers Prev 16:207-13. 2007..The findings support the hypothesis that dietary selenium intake may reduce the incidence of arsenic-related premalignant skin lesions among populations exposed to arsenic exposure from drinking water... - Nutritional influence on risk of high blood pressure in Bangladesh: a population-based cross-sectional studyYu Chen
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA
Am J Clin Nutr 84:1224-32. 2006..The nutritional determinants of hypertension in Bangladesh and other low-income countries are largely unknown... - Modification of risk of arsenic-induced skin lesions by sunlight exposure, smoking, and occupational exposures in BangladeshYu Chen
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
Epidemiology 17:459-67. 2006..Because most arsenic-induced skin cancers arise from these skin lesions, treatment and remediation plans should take into consideration these etiologic cofactors... - Association between arsenic exposure from drinking water and plasma levels of soluble cell adhesion moleculesYu Chen
Departments of Environmental Medicine and Medicine, and New York University Cancer Institute, New York University School of Medicine, New York, New York 10016, USA
Environ Health Perspect 115:1415-20. 2007..Epidemiologic studies of cardiovascular disease risk factors and appropriate biomarkers in populations exposed to a wide range of arsenic levels are a public health research priority... - Estrogen-biosynthesis gene CYP17 and its interactions with reproductive, hormonal and lifestyle factors in breast cancer risk: results from the Long Island Breast Cancer Study ProjectYu Chen
Department of Environmental Medicine and New York University Cancer Institute, New York University School of Medicine, New York, NY 10016, USA
Carcinogenesis 29:766-71. 2008..In conclusion, the findings suggest that the CYP17 variant C allele may increase breast cancer risk in conjunction with long-term HRT use and high BMI in postmenopausal women... - Dietary intake of methionine, cysteine, and protein and urinary arsenic excretion in BangladeshJulia E Heck
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA
Environ Health Perspect 117:99-104. 2009..Once ingested, arsenic is metabolized via methylation and excreted in urine. Knowledge about nutritional factors affecting individual variation in methylation is limited... - Arsenic exposure from drinking water and mortality from cardiovascular disease in Bangladesh: prospective cohort studyYu Chen
Department of Environmental Medicine, New York University School of Medicine, New York, NY 10016, USA
BMJ 342:d2431. 2011..To evaluate the association between arsenic exposure and mortality from cardiovascular disease and to assess whether cigarette smoking influences the association... - Protective effects of B vitamins and antioxidants on the risk of arsenic-related skin lesions in BangladeshLydia B Zablotska
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA
Environ Health Perspect 116:1056-62. 2008..The mitigating effects of diet on arsenic-related premalignant skin lesions are largely unknown... - Socioeconomic status and risk for arsenic-related skin lesions in BangladeshMaria Argos
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA
Am J Public Health 97:825-31. 2007..In this study, we explored the association between socioeconomic status and arsenic toxicity... - Blood arsenic as a biomarker of arsenic exposure: results from a prospective studyMarni Hall
Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University Medical Center, 60 Haven Avenue B1, New York, NY 10032, USA
Toxicology 225:225-33. 2006..This prospective study confirms the increased risk of skin lesions in relation to As concentrations in blood, urine and water and also establishes that BAs is a useful biomarker of As exposure in this study population... - ARN-509: a novel antiandrogen for prostate cancer treatmentNicola J Clegg
Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Cancer Res 72:1494-503. 2012..Our findings offer preclinical proof of principle for ARN-509 as a promising therapeutic in both castration-sensitive and castration-resistant forms of prostate cancer... - A CYP19 (aromatase) polymorphism is associated with increased premenopausal breast cancer riskKathryn E Talbott
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, 10032, USA
Breast Cancer Res Treat 111:481-7. 2008..The finding supports the potential role of variation in estrogen biosynthesis genes in premenopausal breast cancer risk... - Variants in estrogen metabolism and biosynthesis genes and urinary estrogen metabolites in women with a family history of breast cancerHeather Greenlee
Department of Epidemiology, Mailman School of Public Health, Columbia University, 722 West 168th Street, 7th Floor, New York, NY 10032, USA
Breast Cancer Res Treat 102:111-7. 2007.... - Arsenic exposure from drinking water and risk of premalignant skin lesions in Bangladesh: baseline results from the Health Effects of Arsenic Longitudinal StudyHabibul Ahsan
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
Am J Epidemiol 163:1138-48. 2006..53, 5.44), and 5.39 (95% CI: 3.69, 7.86), respectively. The effect seemed to be influenced by gender, age, and body mass index. These findings provide information that should be considered in future research and policy decisions... - Reduction in urinary arsenic levels in response to arsenic mitigation efforts in Araihazar, BangladeshYu Chen
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA
Environ Health Perspect 115:917-23. 2007..There is a need to identify and evaluate an effective mitigation program for arsenic exposure from drinking water in Bangladesh... - Arsenic exposure and anemia in Bangladesh: a population-based studyJulia E Heck
Department of Epidemiology, Mailman School of Public Health, College of Physicians and Surgeons, Columbia University, New York, NY, USA
J Occup Environ Med 50:80-7. 2008..The purpose of this study was to examine the association between arsenic exposure and anemia, based on blood hemoglobin concentration... - Prevalence of arsenic exposure from drinking water and awareness of its health risks in a Bangladeshi population: results from a large population-based studyFaruque Parvez
Mailman School of Public Health, Columbia University, New York, New York 10032, USA
Environ Health Perspect 114:355-9. 2006..Increasing knowledge of the health consequences of As may be an important element in facilitating remediation... - Aflatoxin B1 and polycyclic aromatic hydrocarbon adducts, p53 mutations and p16 methylation in liver tissue and plasma of hepatocellular carcinoma patientsYu Jing Zhang
Department of Environmental Health Science, Mailman School of Public Health of Columbia University, New York, NY 10032, USA
Int J Cancer 119:985-91. 2006..These data suggest that genetic, epigenetic and environmental exposure biomarkers in plasma may help in estimating the risk for the development of HCC... - A prospective study of respiratory symptoms associated with chronic arsenic exposure in Bangladesh: findings from the Health Effects of Arsenic Longitudinal Study (HEALS)Faruque Parvez
Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York, USA
Thorax 65:528-33. 2010..A total of 7.31, 9.95 and 2.03% of the 11 746 participants completing 4 years of active follow-up reported having a chronic cough, breathing problem or blood in their sputum, respectively, as assessed by trained physicians... - Variants in estrogen-biosynthesis genes CYP17 and CYP19 and breast cancer risk: a family-based genetic association studyHabibul Ahsan
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA
Breast Cancer Res 7:R71-81. 2005.... - Arsenic exposure from drinking water and dyspnoea risk in Araihazar, Bangladesh: a population-based studyGene R Pesola
Division of Pulmonary and Critical Care Medicine, Dept of Medicine, Harlem Hospital, Columbia University, New York, NY 10037, USA
Eur Respir J 39:1076-83. 2012..This study suggests that mandated well water testing for arsenic with reduction in exposure may significantly reduce diseases that manifest as dyspnoea, usually cardiac or pulmonary... - Protein and amino acid intakes in a rural area of BangladeshJulia E Heck
Department of Epidemiology, Columbia University, New York, USA
Food Nutr Bull 31:206-13. 2010..Few studies have described protein and amino acid intakes in rural Bangladesh, a country with considerable undernutrition... - Folate and arsenic metabolism: a double-blind, placebo-controlled folic acid-supplementation trial in BangladeshMary V Gamble
Departments of Environmental Health Sciences, Columbia University, New York, NY, USA
Am J Clin Nutr 84:1093-101. 2006..Consequently, folate nutritional status may influence arsenic methylation and toxicity... - Arsenic exposure from drinking-water and carotid artery intima-medial thickness in healthy young adults in BangladeshYu Chen
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, 10032, USA
J Health Popul Nutr 24:253-7. 2006.... - A randomized, double-blind placebo-controlled trial evaluating the effects of vitamin E and selenium on arsenic-induced skin lesions in BangladeshWendy J Verret
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
J Occup Environ Med 47:1026-35. 2005..CONCLUSIONS: Supplementation with vitamin E and selenium, either alone or in combination, slightly improved skin lesion status, although the improvement was not statistically significant... - No association between arsenic exposure from drinking water and diabetes mellitus: a cross-sectional study in BangladeshYu Chen
Department of Environmental Medicine, New York University School of Medicine, New York, New York, USA
Environ Health Perspect 118:1299-305. 2010..The long-term effects of arsenic exposure from drinking water at levels < 300 microg/L and the risk of diabetes mellitus remains a controversial topic... - Nonmalignant respiratory effects of chronic arsenic exposure from drinking water among never-smokers in BangladeshFaruque Parvez
Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA
Environ Health Perspect 116:190-5. 2008..The association with nonmalignant respiratory illnesses has not been well established because the assessments of respiratory symptoms may be influenced by recall bias or interviewer bias because participants had visible skin lesions... - Body mass index and diabetes in Asia: a cross-sectional pooled analysis of 900,000 individuals in the Asia cohort consortiumPaolo Boffetta
Mount Sinai School of Medicine, The Tisch Cancer Institute, New York, New York, United States of America
PLoS ONE 6:e19930. 2011..The shape of the association of overweight and obesity with diabetes risk and its overall impact have not been adequately studied in Asia... - Do placental genes affect maternal breast cancer? Association between offspring's CGB5 and CSH1 gene variants and maternal breast cancer riskYu Chen
Department of Environmental Medicine, New York University Cancer Institute, New York University School of Medicine, New York, NY, USA
Cancer Res 68:9729-34. 2008..90; 95% CI, 0.53-1.51; P for interaction=0.04). The findings suggest that placental CGB5 genotype may be predictive of maternal post-pregnancy breast cancer risk among women who give birth early in life... - Arsenic exposure in Latin America: biomarkers, risk assessments and related health effectsTyler R McClintock
New York University School of Medicine, New York University, New York, NY, USA
Sci Total Environ 429:76-91. 2012..Targeted future studies will not only yield a better understanding of the public health impact of As in Latin America populations, but also allow for effective and timely mitigation efforts... - A prospective study of tobacco smoking and mortality in BangladeshFen Wu
Department of Population Health, New York University School of Medicine, New York, New York, United States of America
PLoS ONE 8:e58516. 2013..Limited data are available on smoking-related mortality in low-income countries, where both chronic disease burden and prevalence of smoking are increasing... - Susceptibility to arsenic-induced hyperkeratosis and oxidative stress genes myeloperoxidase and catalaseHabibul Ahsan
Department of Epidemiology, Mailman School of Public Health, Columfbia University, Room 720G, 722 West 168th Street, New York, NY 10032, USA
Cancer Lett 201:57-65. 2003..Our findings, although based on small numbers, suggest that the oxidative stress genes MPO and CAT may influence the risk of arsenic-induced premalignant hyperkeratotic skin lesions... - Betel quid chewing in rural Bangladesh: prevalence, predictors and relationship to blood pressureJulia E Heck
Department of Epidemiology, University of California, Los Angeles, CA, USA
Int J Epidemiol 41:462-71. 2012..The purpose of our study was to examine the prevalence and predictors of betel quid chewing in a rural area of Bangladesh, and determine its effects on body mass index (BMI) and blood pressure... - Temporal reproducibility of taurine measurements in frozen serum of healthy postmenopausal womenOktawia P Wójcik
Department of Environmental Medicine, New York University School of Medicine, 650 First Avenue, 5th Floor, New York, NY 10016 3240, USA
Br J Nutr 104:629-32. 2010..The CV was 7 %. These results indicate that the mean of two or more annual measurements of serum taurine is a sufficiently reliable measure of long-term serum levels that can be used in epidemiological studies... - Helicobacter pylori colonization is inversely associated with childhood asthmaYu Chen
Department of Environmental Medicine, School of Medicine, New York University, New York, New York 10016, USA
J Infect Dis 198:553-60. 2008..Asthma, a serious health problem worldwide, is becoming more common. Colonization with Helicobacter pylori, a major human indigenous (commensal) microbe, during early life may be relevant to the risk of childhood asthma... - Health Effects of Arsenic Longitudinal Study (HEALS): description of a multidisciplinary epidemiologic investigationHabibul Ahsan
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
J Expo Sci Environ Epidemiol 16:191-205. 2006..HEALS is a valuable resource for examining novel research questions on the health effects of As exposure... - Does Helicobacter pylori protect against asthma and allergy?Martin J Blaser
Department of Medicine, New York University School of Medicine, 550 First Avenue OBV A606, New York, NY 10016, USA
Gut 57:561-7. 2008 - ETV1 is a lineage survival factor that cooperates with KIT in gastrointestinal stromal tumoursPing Chi
Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA
Nature 467:849-53. 2010..It also represents a novel mechanism of oncogenic transcription factor activation... - A family-based genetic association study of variants in estrogen-metabolism genes COMT and CYP1B1 and breast cancer riskHabibul Ahsan
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
Breast Cancer Res Treat 85:121-31. 2004.... - Determinants of oral health care utilization among diverse groups of immigrants in New York CityGustavo D Cruz
Department of Epidemiology and Health Promotion, College of Dentistry, New York University, 250 Park Avenue South, New York, N Y 10003 1402, USA
J Am Dent Assoc 141:871-8. 2010..Few studies have examined utilization of oral health care services among immigrants. The authors examined the determinants of utilization of oral health care among a diverse group of immigrants in New York City... - Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancerBrett S Carver
Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Cancer Cell 19:575-86. 2011.... - Association between Selected Oral Pathogens and Gastric Precancerous LesionsChristian R Salazar
Department of Epidemiology and Health Promotion, New York University College of Dentistry, New York, New York, United States of America Department of Epidemiology, Columbia University Mailman School of Public Health, New York, New York, United States of America
PLoS ONE 8:e51604. 2013..03-0.06). Among individuals with periodontal disease, high levels of colonization of periodontal pathogens are associated with an increased risk of gastric precancerous lesions... - Validity of a food-frequency questionnaire for a large prospective cohort study in BangladeshYu Chen
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, USA
Br J Nutr 92:851-9. 2004..To our knowledge, the present study is the first to document the validity of a FFQ with the use of 7 d FD in a Bangladeshi population... - Serum taurine and risk of coronary heart disease: a prospective, nested case-control studyOktawia P Wójcik
Department of Environmental Medicine, New York University School of Medicine, 650 First Avenue, 5th Floor, New York, NY 10016 3240, USA
Eur J Nutr 52:169-78. 2013..Taurine (2-aminoethanesulfonic acid), a molecule obtained from diet, is involved in bile acid conjugation, blood pressure regulation, anti-oxidation and anti-inflammation. We performed the first prospective study of taurine and CHD risk... - Association between oral health and gastric precancerous lesionsChristian R Salazar
Department of Epidemiology and Health Promotion, New York University College of Dentistry, New York, NY 10003, USA
Carcinogenesis 33:399-403. 2012..7%)], independent of potential confounders. Our findings demonstrate that specific oral health conditions and behaviors such as gingival bleeding and tooth flossing are associated with gastric precancerous lesions... - NudE and NudEL are required for mitotic progression and are involved in dynein recruitment to kinetochoresStephanie A Stehman
Department of Pathology and Cell Biology, Columbia University, New York, NY 10032, USA
J Cell Biol 178:583-94. 2007..Together, these results identify a common function for NudE and NudEL in mitotic progression and identify an alternative mechanism for dynein recruitment to and regulation at kinetochores... - DNA repair gene XPD and susceptibility to arsenic-induced hyperkeratosisHabibul Ahsan
Department of Epidemiology, Mailman School of Public Health, Columbia University, Room 18 129, 622 West 168th Street, New York, NY 10032, USA
Toxicol Lett 143:123-31. 2003..Future larger studies are needed to confirm this novel finding and investigate how combinations of different candidate genes and/or other host and environmental factors may influence the risk of arsenic induced skin and other cancers... - Silencing of glutathione S-transferase P1 by promoter hypermethylation and its relationship to environmental chemical carcinogens in hepatocellular carcinomaYu Jing Zhang
Department of Environmental Health Sciences, Mailman School of Public Health of Columbia University, 701 West 168th Street, New York, NY 10032, USA
Cancer Lett 221:135-43. 2005..The mechanism by which environmental exposures induce epigenetic changes in HCC needs further analysis... - Anti-androgens and androgen-depleting therapies in prostate cancer: new agents for an established targetYu Chen
Genitourinary Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Lancet Oncol 10:981-91. 2009..Both agents are undergoing phase 3 testing. Here, we review the basic science and clinical development of these and other agents... - Inverse associations of Helicobacter pylori with asthma and allergyYu Chen
Department of Environmental Medicine, New York University School of Medicine, New York, USA
Arch Intern Med 167:821-7. 2007..Acquisition of Helicobacter pylori, which predominantly occurs before age 10 years, may reduce risks of asthma and allergy... - Inflammatory bowel disease in patients with celiac diseaseAlice Yang
Department of Medicine, Pathology and Herbert Irving Comprehensive Cancer Center, Columbia University College of Physicians and Surgeons, New York, New York, USA
Inflamm Bowel Dis 11:528-32. 2005..48-8.56) and for Crohn's disease of 8.49 (95% confidence interval, 3.53-20.42). CONCLUSION: Within our cohort of patients with celiac disease, IBD was significantly more common than in the general population... - Association between body-mass index and risk of death in more than 1 million AsiansWei Zheng
Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, TN, USA
N Engl J Med 364:719-29. 2011..Most studies that have evaluated the association between the body-mass index (BMI) and the risks of death from any cause and from specific causes have been conducted in populations of European origin... - Quantitation of major human cutaneous bacterial and fungal populationsZhan Gao
Department of Medicine, New York University Langone Medical Center, New York, New York 10016, USA
J Clin Microbiol 48:3575-81. 2010..These results provide the first quantitation of the site and host specificities of major bacterial and fungal populations in human skin and present simple methods for their assessment in studies of disease... - The association of immigration and acculturation attributes with oral health among immigrants in New York CityGustavo D Cruz
New York University College of Dentistry, Department of Epidemiology and Health Promotion, 250 Park Avenue South, Sixth Floor, New York, NY 10003, USA
Am J Public Health 99:S474-80. 2009..We examined associations between immigration and acculturation attributes and oral disease among immigrants... - The potential protective effects of taurine on coronary heart diseaseOktawia P Wójcik
Department of Environmental Medicine, New York University School of Medicine, 650 FirstAvenue, New York, NY 10016, USA
Atherosclerosis 208:19-25. 2010..We also discuss shortcomings of the human studies that need to be addressed in the future. The identification of taurine as a preventive factor for CHD may be of great public health importance... - Prostate cancer in 2011: Hitting old targets better and identifying new targetsYu Chen
Human Oncology and Pathogenesis Program and Department of Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA
Nat Rev Clin Oncol 9:70-2. 2012..These outcomes contrasted with the heightened controversy generated by the recommendation against PSA screening and other early detection strategies... - Cancer burden from arsenic in drinking water in BangladeshYu Chen
Department of Epidemiology, Mailman School of Public Health, Columbia University, 722 W. 168th Street, New York, NY 10032, USA
Am J Public Health 94:741-4. 2004..Results indicated at least a doubling of lifetime mortality risk from liver, bladder, and lung cancers (229.6 vs 103.5 per 100 000 population) in Bangladesh owing to arsenic in drinking water... - Mixer/Bon and FoxH1/Sur have overlapping and divergent roles in Nodal signaling and mesendoderm inductionPrabhat S Kunwar
Developmental Genetics Program, Skirball Institute of Biomolecular Medicine, Department of Cell Biology, New York University School of Medicine, New York, NY 10016, USA
Development 130:5589-99. 2003.... - Collagen synthesis is not altered in women with stress urinary incontinenceYu Chen
The Research Institute, The North Shore Long Island Jewish Health System, New Hyde Park, New York, USA
Neurourol Urodyn 23:367-73. 2004.... - LIS1 RNA interference blocks neural stem cell division, morphogenesis, and motility at multiple stagesJin Wu Tsai
Department of Pathology and Cell Biology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
J Cell Biol 170:935-45. 2005..Finally, axonal growth also ceased. These results identify multiple distinct and novel roles for LIS1 in nucleokinesis and process dynamics and suggest that nuclear position controls neural progenitor cell division... - Development of a second-generation antiandrogen for treatment of advanced prostate cancerChris Tran
Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
Science 324:787-90. 2009..These compounds thus appear to be promising candidates for treatment of advanced prostate cancer... - Inference for causal interactions for continuous exposures under dichotomizationTyler J VanderWeele
Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, Massachusetts 02115, USA
Biometrics 67:1414-21. 2011..The results in this article are applied to a study of the interactive effects between smoking and arsenic exposure from well water in producing skin lesions...
Research Grants
- Genetic Susceptibilty to Cardiovascular Effects of Arsenic ExposureYu Chen; Fiscal Year: 2010..The findings may also improve risk assessment of health effects of arsenic exposure. ..