F Xavier Castellanos

Summary

Affiliation: New York University School of Medicine
Country: USA

Publications

  1. pmc Cingulate-precuneus interactions: a new locus of dysfunction in adult attention-deficit/hyperactivity disorder
    F Xavier Castellanos
    Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, New York University Child Study Center, New York, NY 10016, USA
    Biol Psychiatry 63:332-7. 2008
  2. doi request reprint Network homogeneity reveals decreased integrity of default-mode network in ADHD
    Lucina Q Uddin
    The Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, New York University Child Study Center, New York, NY 10016, USA
    J Neurosci Methods 169:249-54. 2008
  3. pmc Relationship between cingulo-insular functional connectivity and autistic traits in neurotypical adults
    Adriana Di Martino
    Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, New York University Child Study Center, 215 Lexington Ave, New York, NY 10016, USA
    Am J Psychiatry 166:891-9. 2009
  4. pmc L-dopa modulates functional connectivity in striatal cognitive and motor networks: a double-blind placebo-controlled study
    Clare Kelly
    Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, New York University Child Study Center, New York, New York 10016, USA
    J Neurosci 29:7364-78. 2009
  5. pmc Functional connectivity of default mode network components: correlation, anticorrelation, and causality
    Lucina Q Uddin
    The Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, New York University Child Study Center, New York, New York 10016, USA
    Hum Brain Mapp 30:625-37. 2009
  6. pmc Inter-individual differences in resting-state functional connectivity predict task-induced BOLD activity
    Maarten Mennes
    Phyllis Green and Randolph Cōwen Institute for Pediatric Neuroscience at the NYU Child Study Center, 215 Lexington Avenue 14th Floor, New York, NY 10016, USA
    Neuroimage 50:1690-701. 2010
  7. pmc Aberrant striatal functional connectivity in children with autism
    Adriana Di Martino
    Phyllis Green and Randolph Cōwen Institute for Pediatric Neuroscience, Child Study Center, New York University Langone Medical Center, New York, New York 10016, USA
    Biol Psychiatry 69:847-56. 2011
  8. pmc Low frequency fluctuations reveal integrated and segregated processing among the cerebral hemispheres
    Dylan G Gee
    Phyllis Green and Randolph Cōwen Institute for Pediatric Neuroscience at the NYU Langone Medical Center, New York, NY 10016, USA
    Neuroimage 54:517-27. 2011
  9. pmc Functional connectivity of the human amygdala using resting state fMRI
    Amy Krain Roy
    Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, NYU Child Study Center, New York, NY 10016, USA
    Neuroimage 45:614-26. 2009
  10. pmc Broca's region: linking human brain functional connectivity data and non-human primate tracing anatomy studies
    Clare Kelly
    The Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, New York University Child Study Center, New York, NY 10016, USA
    Eur J Neurosci 32:383-98. 2010

Collaborators

Detail Information

Publications89

  1. pmc Cingulate-precuneus interactions: a new locus of dysfunction in adult attention-deficit/hyperactivity disorder
    F Xavier Castellanos
    Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, New York University Child Study Center, New York, NY 10016, USA
    Biol Psychiatry 63:332-7. 2008
    ....
  2. doi request reprint Network homogeneity reveals decreased integrity of default-mode network in ADHD
    Lucina Q Uddin
    The Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, New York University Child Study Center, New York, NY 10016, USA
    J Neurosci Methods 169:249-54. 2008
    ..Network homogeneity provides a potential alternative method for assessing functional connectivity of specific large-scale networks in clinical populations...
  3. pmc Relationship between cingulo-insular functional connectivity and autistic traits in neurotypical adults
    Adriana Di Martino
    Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, New York University Child Study Center, 215 Lexington Ave, New York, NY 10016, USA
    Am J Psychiatry 166:891-9. 2009
    ....
  4. pmc L-dopa modulates functional connectivity in striatal cognitive and motor networks: a double-blind placebo-controlled study
    Clare Kelly
    Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, New York University Child Study Center, New York, New York 10016, USA
    J Neurosci 29:7364-78. 2009
    ..Our findings suggest that the application of similar experimental pharmacological manipulations in such populations may further our understanding of the role of dopaminergic neurotransmission in those conditions...
  5. pmc Functional connectivity of default mode network components: correlation, anticorrelation, and causality
    Lucina Q Uddin
    The Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, New York University Child Study Center, New York, New York 10016, USA
    Hum Brain Mapp 30:625-37. 2009
    ..Thus, the two major nodes comprising the DMN are differentiated with respect to the specific brain systems with which they interact, suggesting greater heterogeneity within this network than is commonly appreciated...
  6. pmc Inter-individual differences in resting-state functional connectivity predict task-induced BOLD activity
    Maarten Mennes
    Phyllis Green and Randolph Cōwen Institute for Pediatric Neuroscience at the NYU Child Study Center, 215 Lexington Avenue 14th Floor, New York, NY 10016, USA
    Neuroimage 50:1690-701. 2010
    ..These results suggest that a common mechanism governs many brain regions' neural activity during rest and its neural activity during task performance...
  7. pmc Aberrant striatal functional connectivity in children with autism
    Adriana Di Martino
    Phyllis Green and Randolph Cōwen Institute for Pediatric Neuroscience, Child Study Center, New York University Langone Medical Center, New York, New York 10016, USA
    Biol Psychiatry 69:847-56. 2011
    ..Resting state functional magnetic resonance imaging has revealed detailed maps of striatal circuitry in healthy and psychiatric populations and vividly captured maturational changes in striatal circuitry during typical development...
  8. pmc Low frequency fluctuations reveal integrated and segregated processing among the cerebral hemispheres
    Dylan G Gee
    Phyllis Green and Randolph Cōwen Institute for Pediatric Neuroscience at the NYU Langone Medical Center, New York, NY 10016, USA
    Neuroimage 54:517-27. 2011
    ..We discuss implications for leading models of interhemispheric interaction. The future application of our analyses may provide important insight into impaired interhemispheric processing in clinical and aging populations...
  9. pmc Functional connectivity of the human amygdala using resting state fMRI
    Amy Krain Roy
    Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, NYU Child Study Center, New York, NY 10016, USA
    Neuroimage 45:614-26. 2009
    ..These findings suggest that resting state fMRI can be used to investigate human amygdala networks at a greater level of detail than previously appreciated, allowing for the further advancement of translational models...
  10. pmc Broca's region: linking human brain functional connectivity data and non-human primate tracing anatomy studies
    Clare Kelly
    The Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, New York University Child Study Center, New York, NY 10016, USA
    Eur J Neurosci 32:383-98. 2010
    ....
  11. pmc The oscillating brain: complex and reliable
    Xi Nian Zuo
    Phyllis Green and Randolph Cōwen Institute for Pediatric Neuroscience at the New York University Child Study Center, New York, NY, USA
    Neuroimage 49:1432-45. 2010
    ..These results suggest that amplitude measures of LFO can contribute to further between-group characterization of existing and future "resting-state" fMRI datasets...
  12. pmc The restless brain: attention-deficit hyperactivity disorder, resting-state functional connectivity, and intrasubject variability
    F Xavier Castellanos
    Neidich Professor of Child and Adolescent Psychiatry, Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, NYU Child Study Center, New York, New York, USA
    Can J Psychiatry 54:665-72. 2009
    ..To highlight recent advances in the conceptualization of attention-deficit hyperactivity disorder (ADHD) emerging from neuroimaging and endophenotypic approaches...
  13. ncbi request reprint An fMRI examination of developmental differences in the neural correlates of uncertainty and decision-making
    Amy L Krain
    NYU Child Study Center, NYU School of Medicine, New York, NY 10016, USA
    J Child Psychol Psychiatry 47:1023-30. 2006
    ..The present study examines potential developmental differences in frontal regions associated with uncertain decision-making, and tests the impact of IU on these circuits...
  14. pmc Decomposing intra-subject variability in children with attention-deficit/hyperactivity disorder
    Adriana Di Martino
    Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, NYU Child Study Center, New York, NY 10016, USA
    Biol Psychiatry 64:607-14. 2008
    ..Here, we investigated whether these slow RT fluctuations add unique differentiating information beyond the global increase in RT-SD...
  15. pmc Reduced interhemispheric resting state functional connectivity in cocaine addiction
    Clare Kelly
    Phyllis Green and Randolph Cōwen Institute for Pediatric Neuroscience at the New York University Child Study Center, New York, New York 10016, USA
    Biol Psychiatry 69:684-92. 2011
    ..We examined interhemispheric resting-state functional connectivity (RSFC) in cocaine dependence using a recently validated approach, voxel-mirrored homotopic connectivity...
  16. pmc Linking inter-individual differences in neural activation and behavior to intrinsic brain dynamics
    Maarten Mennes
    Phyllis Green and Randolph Cōwen Institute for Pediatric Neuroscience at the NYU Child Study Center, New York, NY 10016, USA
    Neuroimage 54:2950-9. 2011
    ..These results support the emerging hypothesis that the brain's repertoire of responses to the external world are represented and updated in the brain's intrinsic functional architecture...
  17. doi request reprint Development of anterior cingulate functional connectivity from late childhood to early adulthood
    A M Clare Kelly
    Phyllis Green and Randolph Cōwen Institute for Pediatric Neuroscience at the NYU Child Study Center, New York, NY 10016, USA
    Cereb Cortex 19:640-57. 2009
    ..Moreover, given that ICNs are thought to have an anatomical basis in neuronal connectivity, measures of FC may provide a quantitative index of brain maturation in healthy subjects and those with neurodevelopmental disorders...
  18. pmc Response time intra-subject variability: commonalities between children with autism spectrum disorders and children with ADHD
    Nicoletta Adamo
    Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, NYU Child Study Center, New York University Langone Medical Center, One Park Avenue, 8th Floor, New York, NY, 10016, USA
    Eur Child Adolesc Psychiatry 23:69-79. 2014
    ..These results suggest that children with ADHD and those with ASD(+) share common underlying pathophysiological mechanisms of RT-ISV. ..
  19. ncbi request reprint The neural correlates of attention deficit hyperactivity disorder: an ALE meta-analysis
    Steven G Dickstein
    NYU Child Study Center, New York, NY 10016, USA
    J Child Psychol Psychiatry 47:1051-62. 2006
    ..The present work provides an objective, unbiased statistically-based meta-analysis of published functional neuroimaging studies of ADHD...
  20. pmc Examining autistic traits in children with ADHD: does the autism spectrum extend to ADHD?
    Rebecca Grzadzinski
    Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, Child Study Center of the NYU Langone Medical Center, 215 Lexington Avenue, New York, NY 10016, USA
    J Autism Dev Disord 41:1178-91. 2011
    ..These results highlight the importance of specifically examining autistic traits in children with ADHD for better characterization in studies of the underlying physiopathology and treatment...
  21. pmc The balance between feeling and knowing: affective and cognitive empathy are reflected in the brain's intrinsic functional dynamics
    Christine L Cox
    Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience at NYU Child Study Center, 215 Lexington Ave, New York, NY 10016, USA
    Soc Cogn Affect Neurosci 7:727-37. 2012
    ....
  22. pmc Toward systems neuroscience of ADHD: a meta-analysis of 55 fMRI studies
    Samuele Cortese
    Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, Child Study Center of the NYU Langone Medical Center, New York, USA
    Am J Psychiatry 169:1038-55. 2012
    ..The authors performed a comprehensive meta-analysis of task-based functional MRI studies of attention deficit hyperactivity disorder (ADHD)...
  23. pmc Personality is reflected in the brain's intrinsic functional architecture
    Jonathan S Adelstein
    Phyllis Green and Randolph Cōwen Institute for Pediatric Neuroscience at the NYU Child Study Center, New York University Langone Medical Center, New York, New York, United States of America
    PLoS ONE 6:e27633. 2011
    ..This suggests that although a fundamental, core functional architecture is preserved across individuals, variable connections outside of that core encompass the inter-individual differences in personality that motivate diverse responses...
  24. pmc Growing together and growing apart: regional and sex differences in the lifespan developmental trajectories of functional homotopy
    Xi Nian Zuo
    Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, New York University Langone Medical Center, New York, New York 10016, USA
    J Neurosci 30:15034-43. 2010
    ..Evidence of robust developmental effects in homotopic RSFC across the lifespan should serve to motivate studies of the physiological mechanisms underlying functional homotopy in neurodegenerative and psychiatric disorders...
  25. pmc Your resting brain CAREs about your risky behavior
    Christine L Cox
    Phyllis Green and Randolph Cōwen Institute for Pediatric Neuroscience at the New York University Child Study Center, New York University Langone Medical Center, New York, New York, United States of America
    PLoS ONE 5:e12296. 2010
    ..What remains to be understood are the interactions between these regions and their relation to individual differences in personality variables associated with real-world risk-taking...
  26. pmc Resting-state functional connectivity indexes reading competence in children and adults
    Maki S Koyama
    Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience at New York University Child Study Center, New York, New York 10016, USA
    J Neurosci 31:8617-24. 2011
    ....
  27. pmc The resting brain: unconstrained yet reliable
    Zarrar Shehzad
    Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, NYU Child Study Center, New York, NY 10016, USA
    Cereb Cortex 19:2209-29. 2009
    ..Finally, hierarchical clustering solutions were highly reproducible, both across participants and sessions. Our findings provide a solid foundation for continued examination of resting state fcMRI in typical and atypical populations...
  28. pmc Residual functional connectivity in the split-brain revealed with resting-state functional MRI
    Lucina Q Uddin
    New York University Child Study Center, New York, NY 10016, USA
    Neuroreport 19:703-9. 2008
    ..Such continued interhemispheric interaction suggests that, at least in part, cortical networks in the brain can be coordinated by subcortical mechanisms...
  29. pmc Functional brain correlates of social and nonsocial processes in autism spectrum disorders: an activation likelihood estimation meta-analysis
    Adriana Di Martino
    Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience at the New York University NYU Child Study Center, New York, New York 10016, USA
    Biol Psychiatry 65:63-74. 2009
    ..Here, we provide an objective, unbiased survey of functional brain abnormalities in ASD, related to both social and nonsocial processing...
  30. pmc The extrinsic and intrinsic functional architectures of the human brain are not equivalent
    Maarten Mennes
    Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, NYU Child Study Center, New York, NY 10016, USA
    Cereb Cortex 23:223-9. 2013
    ..Appreciating the full repertoire of dynamic neural responses will continue to require task-based functional magnetic resonance imaging approaches...
  31. ncbi request reprint Regional variation in interhemispheric coordination of intrinsic hemodynamic fluctuations
    David E Stark
    Phyllis Green and Randolph Cōwen Institute for Pediatric Neuroscience at the New York University Child Study Center, New York, New York 10016, USA
    J Neurosci 28:13754-64. 2008
    ..This novel method of examining interhemispheric coordination may yield insights regarding diverse disease processes as well as healthy development...
  32. pmc Reliable intrinsic connectivity networks: test-retest evaluation using ICA and dual regression approach
    Xi Nian Zuo
    Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, New York University Child Study Center, New York, NY, USA
    Neuroimage 49:2163-77. 2010
    ..In summary, TC-GICA combined with dual regression is an effective and reliable approach to exploratory analyses of resting state fMRI data...
  33. ncbi request reprint Recent advances in structural and functional brain imaging studies of attention-deficit/hyperactivity disorder
    A M Clare Kelly
    Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, NYU Child Study Center, New York, NY 10016, USA
    Curr Psychiatry Rep 9:401-7. 2007
    ..These developments allow us to conclude that neuroimaging studies of ADHD will increasingly inform our understanding of the neuronal substrates of ADHD...
  34. doi request reprint Shared and distinct intrinsic functional network centrality in autism and attention-deficit/hyperactivity disorder
    Adriana Di Martino
    Institute for Pediatric Neuroscience of the Child Study Center, NYU Langone Medical Center, New York, New York
    Biol Psychiatry 74:623-32. 2013
    ..Here, we aimed to examine patterns of dysconnection in school-age children with ASD and ADHD and typically developing children who completed a resting state functional magnetic resonance imaging scan...
  35. ncbi request reprint A functional magnetic resonance imaging investigation of uncertainty in adolescents with anxiety disorders
    Amy L Krain
    New York University Child Study Center, New York University School of Medicine, New York, NY 10016, USA
    Biol Psychiatry 63:563-8. 2008
    ..As such, the present study examines the relationship between IU and neural responses to uncertainty in anxious adolescents...
  36. pmc A convergent functional architecture of the insula emerges across imaging modalities
    Clare Kelly
    Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, New York University Child Study Center, New York, NY 10016, USA
    Neuroimage 61:1129-42. 2012
    ..projects.nitrc.org, along with the analytic scripts used to perform the parcellations...
  37. pmc Low frequency oscillations of response time explain parent ratings of inattention and hyperactivity/impulsivity
    Maria Angeles Mairena
    Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, NYU Child Study Center, New York, NY 10016, USA
    Eur Child Adolesc Psychiatry 21:101-9. 2012
    ..Results suggest that frequency analyses are a suitable methodology to link behavioral responses to putative underlying physiological processes...
  38. pmc Brain gray matter deficits at 33-year follow-up in adults with attention-deficit/hyperactivity disorder established in childhood
    Erika Proal
    Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, Child Study Center, New York University Langone School of Medicine, USA
    Arch Gen Psychiatry 68:1122-34. 2011
    ..We present, to our knowledge, the first prospective study combining cortical thickness and voxel-based morphometry in adults diagnosed as having ADHD in childhood...
  39. ncbi request reprint Imaging human connectomes at the macroscale
    R Cameron Craddock
    Center for the Developing Brain, Child Mind Institute, New York, New York, USA
    Nat Methods 10:524-39. 2013
    ..We highlight emerging areas of development and inquiry and emphasize the importance of integrating structural and functional perspectives on brain architecture...
  40. pmc Obesity in men with childhood ADHD: a 33-year controlled, prospective, follow-up study
    Samuele Cortese
    Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, Child Study Center of the NYU Langone Medical Center, New York, NY, USA
    Pediatrics 131:e1731-8. 2013
    ..We predicted higher BMI and obesity rates in: (1) men with, versus men without, childhood ADHD; (2) men with persistent, versus men with remitted, ADHD; and (3) men with persistent or remitted ADHD versus those without childhood ADHD...
  41. pmc A comprehensive assessment of regional variation in the impact of head micromovements on functional connectomics
    Chao Gan Yan
    Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA
    Neuroimage 76:183-201. 2013
    ..The implications of our findings for decision-making regarding the assessment and correction of motion are discussed, as are insights into potential differences among volume-based metrics of motion...
  42. pmc Dimensional brain-behavior relationships in children with attention-deficit/hyperactivity disorder
    Camille Chabernaud
    Phyllis Green and Randolph Cōwen Institute for Pediatric Neuroscience at the New York University Child Study Center, Langone Medical Center, New York, New York, USA
    Biol Psychiatry 71:434-42. 2012
    ..Additionally, we examined whether dimensional brain-behavior relationships are modified by the presence of a categorically defined illness, attention-deficit/hyperactivity disorder (ADHD)...
  43. ncbi request reprint Mapping the functional connectivity of anterior cingulate cortex
    Daniel S Margulies
    The Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, NYU Child Study Center, 215 Lexington Avenue, 14th Floor, New York, NY 10016, USA
    Neuroimage 37:579-88. 2007
    ..We discuss the implications of our work for understanding ACC function and potential applications to clinical populations...
  44. ncbi request reprint Competition between functional brain networks mediates behavioral variability
    A M Clare Kelly
    The Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, NYU Child Study Center, New York, NY 10016, USA
    Neuroimage 39:527-37. 2008
    ..We discuss the implications of these findings for our understanding of the behavioral significance of spontaneous brain activity, in both healthy and clinical populations...
  45. pmc Reading networks at rest
    Maki S Koyama
    Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, New York University Child Study Center, New York, NY 10016, USA
    Cereb Cortex 20:2549-59. 2010
    ..In conclusion, the current study supports the utility of resting-state fMRI for investigating reading networks and has direct relevance for the understanding of reading disorders such as dyslexia...
  46. pmc Striatum-based circuitry of adolescent depression and anhedonia
    Vilma Gabbay
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029 6574, USA
    J Am Acad Child Adolesc Psychiatry 52:628-41.e13. 2013
    ..Addressing this clinical phenomenon, we aimed to use intrinsic functional connectivity (iFC) to study striatum-based circuitry in relation to categorical diagnosis of MDD and anhedonia severity...
  47. ncbi request reprint Neural and behavioral correlates of expectancy violations in attention-deficit hyperactivity disorder
    Sarah Durston
    Sackler Institute for Developmental Psychobiology, Weill Medical College of Cornell University, New York, USA
    J Child Psychol Psychiatry 48:881-9. 2007
    ..Therefore, we hypothesized that the ability to predict the occurrence of frequent events would be compromised in ADHD, as well as the ability to adapt behavior when expectancy was violated...
  48. ncbi request reprint Default mode network abnormalities in idiopathic generalized epilepsy
    Megan L McGill
    NYU Comprehensive Epilepsy Center, New York University School of Medicine, New York, NY, USA
    Epilepsy Behav 23:353-9. 2012
    ..The observed pattern of disruption provides evidence for integration- and segregation-type network abnormalities and supports aberrant network organization among people with IGE...
  49. pmc Characterizing variation in the functional connectome: promise and pitfalls
    Clare Kelly
    Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, New York University Child Study Center, New York, NY 10016, USA
    Trends Cogn Sci 16:181-8. 2012
    ....
  50. pmc Differential development of human brain white matter tracts
    Davide Imperati
    Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, Child Study Center, Langone Medical Center, New York University, New York City, New York, United States of America
    PLoS ONE 6:e23437. 2011
    ..Our findings demonstrate that data-driven analytic techniques may be fruitfully applied to extant diffusion tensor imaging datasets in normative and neuropsychiatric samples...
  51. pmc Varieties of attention-deficit/hyperactivity disorder-related intra-individual variability
    F Xavier Castellanos
    Institute for Pediatric Neuroscience, New York University, Child Study Center, NYU School of Medicine, New York, New York 10016, USA
    Biol Psychiatry 57:1416-23. 2005
    ..These results highlight the importance of retaining time-series data and quantitatively examining intra-subject measures of variability as a putative endophenotype for ADHD...
  52. pmc Clinical applications of the functional connectome
    F Xavier Castellanos
    Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, New York University Child Study Center, New York, NY 10016, USA
    Neuroimage 80:527-40. 2013
    ..Additionally, we note the need to expand future efforts beyond identification of biomarkers for disease status alone to include clinical variables related to risk, expected treatment response and prognosis. ..
  53. pmc Does childhood attention-deficit/hyperactivity disorder predict risk-taking and medical illnesses in adulthood?
    Maria A Ramos Olazagasti
    New York University Medical Center, New York, NY 10016, USA
    J Am Acad Child Adolesc Psychiatry 52:153-162.e4. 2013
    ..We report causes of death...
  54. pmc Large-scale brain systems in ADHD: beyond the prefrontal-striatal model
    F Xavier Castellanos
    Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, Child Study Center, NYU Langone School of Medicine, New York, NY, USA
    Trends Cogn Sci 16:17-26. 2012
    ....
  55. pmc Resting state functional connectivity correlates of inhibitory control in children with attention-deficit/hyperactivity disorder
    Maarten Mennes
    Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, NYU Langone School of Medicine, NYU Child Study Center New York, NY, USA
    Front Psychiatry 2:83. 2011
    ..Our results demonstrate the utility of RSFC approaches for assessing brain/behavior relationships, and for identifying pathology-related differences in the contributions of neural circuits to cognition and behavior...
  56. ncbi request reprint Characterizing cognition in ADHD: beyond executive dysfunction
    F Xavier Castellanos
    Institute for Pediatric Neuroscience, NYU Child Study Center, 215 Lexington Avenue, New York, NY 10016, USA
    Trends Cogn Sci 10:117-23. 2006
    ..Such a reconceptualization provides a means to transcend the limits of current models of executive dysfunction in ADHD and suggests a plan for future research on cognition grounded in neurophysiological and developmental considerations...
  57. pmc Uncovering putative neural markers of risk avoidance
    Amy Krain Roy
    Department of Psychology, City University of New York, Brooklyn, NY 11210, USA
    Neuropsychologia 49:937-44. 2011
    ..Further, they underline the need to extend neuroimaging research on risk avoidance, and associated anxiety disorders, to posterior cortical regions...
  58. pmc Stimulant and atypical antipsychotic medications for children placed in foster homes
    L Oriana Linares
    Mount Sinai School of Medicine, Adolescent Health Center, New York, New York, United States of America
    PLoS ONE 8:e54152. 2013
    ....
  59. pmc Making data sharing work: the FCP/INDI experience
    Maarten Mennes
    Donders Institute for Brain, Cognition and Behaviour, Dept of Cognitive Neuroscience, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Neuroimage 82:683-91. 2013
    ..We discuss the FCP and INDI in the context of these challenges, highlighting the promise of current initiatives and suggesting solutions for possible pitfalls. ..
  60. doi request reprint A meta-analysis of neuropsychological functioning in patients with early onset schizophrenia and pediatric bipolar disorder
    Rebeca Garcia Nieto
    Child Study Center, New York University Langone Medical Center, New York, NY, USA
    J Clin Child Adolesc Psychol 40:266-80. 2011
    ..Qualitative similarities between the neuropsychological profiles produced by these groups of patients might represent a "continuum of psychosis" or reflect some degree of genetic biological overlap...
  61. ncbi request reprint Distinct neural mechanisms of risk and ambiguity: a meta-analysis of decision-making
    Amy L Krain
    New York University Child Study Center, New York University School of Medicine, 215 Lexington Avenue, New York, NY 10016, USA
    Neuroimage 32:477-84. 2006
    ..These findings provide evidence for the dissociation of neural circuits underlying risky and ambiguous decision-making, reflecting differential involvement of affective "hot" and cognitive "cool" processes...
  62. pmc Testing tic suppression: comparing the effects of dexmethylphenidate to no medication in children and adolescents with attention-deficit/hyperactivity disorder and Tourette's disorder
    Gholson J Lyon
    Department of Child and Adolescent Psychiatry, New York University Child Study Center, New York, New York 10016, USA
    J Child Adolesc Psychopharmacol 20:283-9. 2010
    ..The primary hypothesis is that dMPH will improve behaviorally reinforced tic suppression in a standard tic suppression paradigm (TSP)...
  63. ncbi request reprint [Functional cerebral activity in a state of rest: connectivity networks]
    Erika Proal
    Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, Child Study Center, NYU School of Medicine, 215 Lexington Ave, New York, NY 10016, USA
    Rev Neurol 52:S3-10. 2011
    ..nitrc.org/projects/srsn)...
  64. ncbi request reprint Proceed, with caution: SPECT cerebral blood flow studies of children and adolescents with attention deficit hyperactivity disorder
    F Xavier Castellanos
    NYU Child Study Center, New York, New York 10016, USA
    J Nucl Med 43:1630-3. 2002
  65. pmc Neuroimaging of attention-deficit/hyperactivity disorder: current neuroscience-informed perspectives for clinicians
    Samuele Cortese
    Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, Child Study Center of the NYU Langone Medical Center, One Park Avenue, 8th Floor, New York, NY 10016, USA
    Curr Psychiatry Rep 14:568-78. 2012
    ..Although novel analytical techniques are likely to accelerate the pace of translational applications, at the present we advise caution regarding inappropriate commercial misuse of imaging techniques in ADHD...
  66. ncbi request reprint Functional MRI in pediatric neurobehavioral disorders
    Michael Seyffert
    Institute for Pediatric Neuroscience, New York University Child Study Center, New York New York 10016, USA
    Int Rev Neurobiol 67:239-84. 2005
  67. ncbi request reprint Brain development and ADHD
    Amy L Krain
    Institute for Pediatric Neuroscience, NYU Child Study Center, 215 Lexington Avenue, New York, NY 10016, USA
    Clin Psychol Rev 26:433-44. 2006
    ..Differences in gray and white matter have also been examined. The ultimate goal of this research is to determine the underlying neurophysiology of ADHD and how specific phenotypes may be related to alterations in brain structure...
  68. ncbi request reprint [Towards an understanding of the molecular mechanisms underlying the pharmacological treatments of attention deficit hyperactivity disorder]
    F Xavier Castellanos
    Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, Child Study Center, NYU School of Medicine, 215 Lexington Ave, New York, NY 10016, USA
    Rev Neurol 52:S155-60. 2011
    ....
  69. ncbi request reprint Functional neuroimaging of social cognition in pervasive developmental disorders: a brief review
    Adriana Di Martino
    New York University Child Study Center, 577 First Avenue, New York, NY 10016, USA
    Ann N Y Acad Sci 1008:256-60. 2003
    ..Future studies should extend these important initial results to younger and more severely affected subjects...
  70. ncbi request reprint Neuroscience of attention-deficit/hyperactivity disorder: the search for endophenotypes
    F Xavier Castellanos
    New York University Child Study Center, 577 First Avenue, CSC 204, New York, New York 10016 6404, USA
    Nat Rev Neurosci 3:617-28. 2002
  71. ncbi request reprint Longitudinal mapping of cortical thickness and clinical outcome in children and adolescents with attention-deficit/hyperactivity disorder
    Philip Shaw
    Child Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892 1500, USA
    Arch Gen Psychiatry 63:540-9. 2006
    ..Data from a previous prospective study of lobar volumes in children with attention-deficit/hyperactivity disorder (ADHD) are reexamined using a measure of cortical thickness...
  72. ncbi request reprint Attention-deficit/hyperactivity disorder and comorbid disruptive behavior disorders: evidence of pleiotropy and new susceptibility loci
    Mahim Jain
    Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892 3717, USA
    Biol Psychiatry 61:1329-39. 2007
    ..Attention-deficit/hyperactivity disorder (ADHD) comorbid with oppositional defiant disorder (ODD) or conduct disorder (CD) and substance abuse/dependence seems to represent a specific subset within the phenotypic ADHD spectrum...
  73. ncbi request reprint Etiologic subtypes of attention-deficit/hyperactivity disorder: brain imaging, molecular genetic and environmental factors and the dopamine hypothesis
    James M Swanson
    Department of Pediatrics, University of California, Irvine, CA 92612, USA
    Neuropsychol Rev 17:39-59. 2007
    ....
  74. ncbi request reprint Monozygotic twins discordant for attention-deficit/hyperactivity disorder: ascertainment and clinical characteristics
    Wendy S Sharp
    Child Psychology Branch of the NIMH, USA
    J Am Acad Child Adolesc Psychiatry 42:93-7. 2003
    ..Nongenetic factors and phenomenology of attention-deficit/hyperactivity disorder (ADHD) were examined in monozygotic (MZ) twin pairs discordant for ADHD...
  75. ncbi request reprint Spontaneous attentional fluctuations in impaired states and pathological conditions: a neurobiological hypothesis
    Edmund J S Sonuga-Barke
    Developmental Brain and Behaviour Unit, School of Psychology, University of Southampton, Southampton, UK
    Neurosci Biobehav Rev 31:977-86. 2007
    ..Finally, we explore the putative role of default-mode interference as a cause of performance variability in attention deficit/hyperactivity disorder...
  76. ncbi request reprint Polymorphisms of the dopamine D4 receptor, clinical outcome, and cortical structure in attention-deficit/hyperactivity disorder
    Philip Shaw
    Child Psychiatry Branch, Room 3N202, Bldg 10, Center Drive, National Institute of Mental Health, Bethesda, MD 20892, USA
    Arch Gen Psychiatry 64:921-31. 2007
    ..Attention-deficit/hyperactivity disorder (ADHD) is one of the most heritable neuropsychiatric disorders, and a polymorphism within the dopamine D4 receptor (DRD4) gene has been frequently implicated in its pathogenesis...
  77. ncbi request reprint Developmental trajectories of brain volume abnormalities in children and adolescents with attention-deficit/hyperactivity disorder
    F Xavier Castellanos
    Child Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA
    JAMA 288:1740-8. 2002
    ..Various anatomic brain abnormalities have been reported for attention-deficit/hyperactivity disorder (ADHD), with varying methods, small samples, cross-sectional designs, and without accounting for stimulant drug exposure...
  78. pmc Latent class subtyping of attention-deficit/hyperactivity disorder and comorbid conditions
    Maria T Acosta
    National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892 3717, USA
    J Am Acad Child Adolesc Psychiatry 47:797-807. 2008
    ..The aim of this study was to perform LCA in a sample of 1,010 individuals from a nationwide recruitment of unilineal nuclear families with at least one child with ADHD and another child either affected or clearly unaffected...
  79. ncbi request reprint Temporal and probabilistic discounting of rewards in children and adolescents: effects of age and ADHD symptoms
    Anouk Scheres
    Psychology Department, University of Arizona, Tucson, 85721, USA
    Neuropsychologia 44:2092-103. 2006
    ..The decrease in TD as observed in adolescents compared to children may be related to developmental changes in the (dorsolateral) prefrontal cortex. Future research needs to investigate these possibilities...
  80. ncbi request reprint Anatomic brain abnormalities in monozygotic twins discordant for attention deficit hyperactivity disorder
    F Xavier Castellanos
    Child Psychiatry Branch, National Institute of Mental Health NIH, Bethesda, MD, USA
    Am J Psychiatry 160:1693-6. 2003
    ..To examine brain-behavior relationships in attention deficit hyperactivity disorder (ADHD), the authors obtained magnetic resonance imaging (MRI) scans of monozygotic twins discordant for ADHD...
  81. ncbi request reprint Neurologic examination abnormalities in children with bipolar disorder or attention-deficit/hyperactivity disorder
    Daniel P Dickstein
    National Institute of Mental Health, Pediatrics and Developmental Neuropsychiatry Branch, 10 Center Drive MSC 1255, Building 10 Room 4N208, Bethesda MD 20892 1255, USA
    Biol Psychiatry 58:517-24. 2005
    ..To move beyond diagnosis toward unique pathophysiology, we evaluated both ADHD and BPD children for neurologic examination abnormalities (NEAs) in comparison with normal control (NC) children...
  82. ncbi request reprint Shifting-related brain magnetic activity in attention-deficit/hyperactivity disorder
    Fernando Mulas
    Valencian Institute of Pediatric Neurology, Valencia, Spain
    Biol Psychiatry 59:373-9. 2006
    ..Current theories suggest a role for frontal-striatal circuits in the pathogenesis of attention-deficit/hyperactivity disorder (ADHD)...
  83. ncbi request reprint Cerebellar neurotransmission in attention-deficit/hyperactivity disorder: does dopamine neurotransmission occur in the cerebellar vermis?
    Paul E A Glaser
    Department of Psychiatry, University of Kentucky Chandler Medical Center, Lexington, 40536, USA
    J Neurosci Methods 151:62-7. 2006
    ..The presence of DAT may therefore allow for enhanced regulation of NE and not regulation of released DA...
  84. ncbi request reprint Support for association between ADHD and two candidate genes: NET1 and DRD1
    Aaron J Bobb
    Child Psychiatry Branch, NIMH, NIH, Bethesda, Maryland 20892 1600, USA
    Am J Med Genet B Neuropsychiatr Genet 134:67-72. 2005
    ..Because family-based and case-control methods gave divergent results, both should be used in genetic studies of ADHD...
  85. ncbi request reprint Molecular genetic studies of ADHD: 1991 to 2004
    Aaron J Bobb
    Child Psychiatry Branch, NIMH, NIH, 10 Center Drive, Bethesda, MD 20892, USA
    Am J Med Genet B Neuropsychiatr Genet 132:109-25. 2005
    ..All candidate gene approaches continue to face the problem of relatively low power, given modest odds ratios for even the best replicated genes...
  86. ncbi request reprint Attention-deficit/hyperactivity disorder and comorbidities in 18 Paisa Colombian multigenerational families
    Juan D Palacio
    Neurosciences Group, University of Antioquia, Medellin, Colombia
    J Am Acad Child Adolesc Psychiatry 43:1506-15. 2004
    ..This report describes the inclusion strategy and clinical features of participants to facilitate comparisons with other data sets...
  87. pmc Attention-deficit/hyperactivity disorder in a population isolate: linkage to loci at 4q13.2, 5q33.3, 11q22, and 17p11
    Mauricio Arcos-Burgos
    National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892 3717, USA
    Am J Hum Genet 75:998-1014. 2004
    ..The concordance between results from different analytical methods of linkage and the replication of data between two independent studies suggest that these loci truly harbor ADHD susceptibility genes...
  88. ncbi request reprint Cytogenetic abnormalities in attention-deficit/hyperactivity disorder
    Theresa M Bastain
    Child Psychiatry Branch of the NIMH, USA
    J Am Acad Child Adolesc Psychiatry 41:806-10. 2002
    ..To systematically assess the prevalence of fragile X syndrome, velocardiofacial syndrome, and other cytogenetic abnormalities in a group of children with attention-defict/hyperactivity disorder (ADHD)...
  89. ncbi request reprint The ipsilateral silent period in boys with attention-deficit/hyperactivity disorder
    Marjorie A Garvey
    Pediatric Movement Disorders Unit, Human Motor Control Section, MNB, NINDS, National Institutes of Health, Bethesda, MD 20892, USA
    Clin Neurophysiol 116:1889-96. 2005
    ..Characterize maturation of transcallosal inhibition (ipsilateral silent period [iSP]) in attention deficit/hyperactivity disorder (ADHD) using transcranial magnetic stimulation (TMS)...