Research Topics
| F Xavier CastellanosSummaryAffiliation: New York University School of Medicine Country: USA Publications
| Collaborators
|
Detail Information
Publications
Cingulate-precuneus interactions: a new locus of dysfunction in adult attention-deficit/hyperactivity disorderF Xavier Castellanos
Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, New York University Child Study Center, New York, NY 10016, USA
Biol Psychiatry 63:332-7. 2008....
Network homogeneity reveals decreased integrity of default-mode network in ADHDLucina Q Uddin
The Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, New York University Child Study Center, New York, NY 10016, USA
J Neurosci Methods 169:249-54. 2008..Network homogeneity provides a potential alternative method for assessing functional connectivity of specific large-scale networks in clinical populations...- Relationship between cingulo-insular functional connectivity and autistic traits in neurotypical adultsAdriana Di Martino
Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, New York University Child Study Center, 215 Lexington Ave, New York, NY 10016, USA
Am J Psychiatry 166:891-9. 2009.... - L-dopa modulates functional connectivity in striatal cognitive and motor networks: a double-blind placebo-controlled studyClare Kelly
Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, New York University Child Study Center, New York, New York 10016, USA
J Neurosci 29:7364-78. 2009..Our findings suggest that the application of similar experimental pharmacological manipulations in such populations may further our understanding of the role of dopaminergic neurotransmission in those conditions... - Functional connectivity of default mode network components: correlation, anticorrelation, and causalityLucina Q Uddin
The Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, New York University Child Study Center, New York, New York 10016, USA
Hum Brain Mapp 30:625-37. 2009..Thus, the two major nodes comprising the DMN are differentiated with respect to the specific brain systems with which they interact, suggesting greater heterogeneity within this network than is commonly appreciated... - Inter-individual differences in resting-state functional connectivity predict task-induced BOLD activityMaarten Mennes
Phyllis Green and Randolph Cōwen Institute for Pediatric Neuroscience at the NYU Child Study Center, 215 Lexington Avenue 14th Floor, New York, NY 10016, USA
Neuroimage 50:1690-701. 2010..These results suggest that a common mechanism governs many brain regions' neural activity during rest and its neural activity during task performance... - Low frequency fluctuations reveal integrated and segregated processing among the cerebral hemispheresDylan G Gee
Phyllis Green and Randolph Cōwen Institute for Pediatric Neuroscience at the NYU Langone Medical Center, New York, NY 10016, USA
Neuroimage 54:517-27. 2011..We discuss implications for leading models of interhemispheric interaction. The future application of our analyses may provide important insight into impaired interhemispheric processing in clinical and aging populations... - Functional connectivity of the human amygdala using resting state fMRIAmy Krain Roy
Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, NYU Child Study Center, New York, NY 10016, USA
Neuroimage 45:614-26. 2009..These findings suggest that resting state fMRI can be used to investigate human amygdala networks at a greater level of detail than previously appreciated, allowing for the further advancement of translational models... - Aberrant striatal functional connectivity in children with autismAdriana Di Martino
Phyllis Green and Randolph Cōwen Institute for Pediatric Neuroscience, Child Study Center, New York University Langone Medical Center, New York, New York 10016, USA
Biol Psychiatry 69:847-56. 2011..Resting state functional magnetic resonance imaging has revealed detailed maps of striatal circuitry in healthy and psychiatric populations and vividly captured maturational changes in striatal circuitry during typical development... 
An fMRI examination of developmental differences in the neural correlates of uncertainty and decision-makingAmy L Krain
NYU Child Study Center, NYU School of Medicine, New York, NY 10016, USA
J Child Psychol Psychiatry 47:1023-30. 2006..The present study examines potential developmental differences in frontal regions associated with uncertain decision-making, and tests the impact of IU on these circuits...- The oscillating brain: complex and reliableXi Nian Zuo
Phyllis Green and Randolph Cōwen Institute for Pediatric Neuroscience at the New York University Child Study Center, New York, NY, USA
Neuroimage 49:1432-45. 2010..These results suggest that amplitude measures of LFO can contribute to further between-group characterization of existing and future "resting-state" fMRI datasets... - The restless brain: attention-deficit hyperactivity disorder, resting-state functional connectivity, and intrasubject variabilityF Xavier Castellanos
Neidich Professor of Child and Adolescent Psychiatry, Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, NYU Child Study Center, New York, New York, USA
Can J Psychiatry 54:665-72. 2009..To highlight recent advances in the conceptualization of attention-deficit hyperactivity disorder (ADHD) emerging from neuroimaging and endophenotypic approaches... - Broca's region: linking human brain functional connectivity data and non-human primate tracing anatomy studiesClare Kelly
The Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, New York University Child Study Center, New York, NY 10016, USA
Eur J Neurosci 32:383-98. 2010.... - Decomposing intra-subject variability in children with attention-deficit/hyperactivity disorderAdriana Di Martino
Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, NYU Child Study Center, New York, NY 10016, USA
Biol Psychiatry 64:607-14. 2008..Here, we investigated whether these slow RT fluctuations add unique differentiating information beyond the global increase in RT-SD... - Development of anterior cingulate functional connectivity from late childhood to early adulthoodA M Clare Kelly
Phyllis Green and Randolph Cōwen Institute for Pediatric Neuroscience at the NYU Child Study Center, New York, NY 10016, USA
Cereb Cortex 19:640-57. 2009..Moreover, given that ICNs are thought to have an anatomical basis in neuronal connectivity, measures of FC may provide a quantitative index of brain maturation in healthy subjects and those with neurodevelopmental disorders... - Linking inter-individual differences in neural activation and behavior to intrinsic brain dynamicsMaarten Mennes
Phyllis Green and Randolph Cōwen Institute for Pediatric Neuroscience at the NYU Child Study Center, New York, NY 10016, USA
Neuroimage 54:2950-9. 2011..These results support the emerging hypothesis that the brain's repertoire of responses to the external world are represented and updated in the brain's intrinsic functional architecture... - Reduced interhemispheric resting state functional connectivity in cocaine addictionClare Kelly
Phyllis Green and Randolph Cōwen Institute for Pediatric Neuroscience at the New York University Child Study Center, New York, New York 10016, USA
Biol Psychiatry 69:684-92. 2011..We examined interhemispheric resting-state functional connectivity (RSFC) in cocaine dependence using a recently validated approach, voxel-mirrored homotopic connectivity... - Examining autistic traits in children with ADHD: does the autism spectrum extend to ADHD?Rebecca Grzadzinski
Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, Child Study Center of the NYU Langone Medical Center, 215 Lexington Avenue, New York, NY 10016, USA
J Autism Dev Disord 41:1178-91. 2011..These results highlight the importance of specifically examining autistic traits in children with ADHD for better characterization in studies of the underlying physiopathology and treatment... - Toward systems neuroscience of ADHD: a meta-analysis of 55 fMRI studiesSamuele Cortese
Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, Child Study Center of the NYU Langone Medical Center, New York, USA
Am J Psychiatry 169:1038-55. 2012..The authors performed a comprehensive meta-analysis of task-based functional MRI studies of attention deficit hyperactivity disorder (ADHD)... - The balance between feeling and knowing: affective and cognitive empathy are reflected in the brain's intrinsic functional dynamicsChristine L Cox
Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience at NYU Child Study Center, 215 Lexington Ave, New York, NY 10016, USA
Soc Cogn Affect Neurosci 7:727-37. 2012.... - Personality is reflected in the brain's intrinsic functional architectureJonathan S Adelstein
Phyllis Green and Randolph Cōwen Institute for Pediatric Neuroscience at the NYU Child Study Center, New York University Langone Medical Center, New York, New York, United States of America
PLoS ONE 6:e27633. 2011..This suggests that although a fundamental, core functional architecture is preserved across individuals, variable connections outside of that core encompass the inter-individual differences in personality that motivate diverse responses... - Residual functional connectivity in the split-brain revealed with resting-state functional MRILucina Q Uddin
New York University Child Study Center, New York, NY 10016, USA
Neuroreport 19:703-9. 2008..Such continued interhemispheric interaction suggests that, at least in part, cortical networks in the brain can be coordinated by subcortical mechanisms... - The resting brain: unconstrained yet reliableZarrar Shehzad
Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, NYU Child Study Center, New York, NY 10016, USA
Cereb Cortex 19:2209-29. 2009..Finally, hierarchical clustering solutions were highly reproducible, both across participants and sessions. Our findings provide a solid foundation for continued examination of resting state fcMRI in typical and atypical populations... - Functional brain correlates of social and nonsocial processes in autism spectrum disorders: an activation likelihood estimation meta-analysisAdriana Di Martino
Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience at the New York University NYU Child Study Center, New York, New York 10016, USA
Biol Psychiatry 65:63-74. 2009..Here, we provide an objective, unbiased survey of functional brain abnormalities in ASD, related to both social and nonsocial processing... - Resting-state functional connectivity indexes reading competence in children and adultsMaki S Koyama
Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience at New York University Child Study Center, New York, New York 10016, USA
J Neurosci 31:8617-24. 2011.... - Growing together and growing apart: regional and sex differences in the lifespan developmental trajectories of functional homotopyXi Nian Zuo
Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, New York University Langone Medical Center, New York, New York 10016, USA
J Neurosci 30:15034-43. 2010..Evidence of robust developmental effects in homotopic RSFC across the lifespan should serve to motivate studies of the physiological mechanisms underlying functional homotopy in neurodegenerative and psychiatric disorders... - Your resting brain CAREs about your risky behaviorChristine L Cox
Phyllis Green and Randolph Cōwen Institute for Pediatric Neuroscience at the New York University Child Study Center, New York University Langone Medical Center, New York, New York, United States of America
PLoS ONE 5:e12296. 2010..What remains to be understood are the interactions between these regions and their relation to individual differences in personality variables associated with real-world risk-taking... - Reliable intrinsic connectivity networks: test-retest evaluation using ICA and dual regression approachXi Nian Zuo
Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, New York University Child Study Center, New York, NY, USA
Neuroimage 49:2163-77. 2010..In summary, TC-GICA combined with dual regression is an effective and reliable approach to exploratory analyses of resting state fMRI data... - Recent advances in structural and functional brain imaging studies of attention-deficit/hyperactivity disorderA M Clare Kelly
Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, NYU Child Study Center, New York, NY 10016, USA
Curr Psychiatry Rep 9:401-7. 2007..These developments allow us to conclude that neuroimaging studies of ADHD will increasingly inform our understanding of the neuronal substrates of ADHD... - Regional variation in interhemispheric coordination of intrinsic hemodynamic fluctuationsDavid E Stark
Phyllis Green and Randolph Cōwen Institute for Pediatric Neuroscience at the New York University Child Study Center, New York, New York 10016, USA
J Neurosci 28:13754-64. 2008..This novel method of examining interhemispheric coordination may yield insights regarding diverse disease processes as well as healthy development... - A functional magnetic resonance imaging investigation of uncertainty in adolescents with anxiety disordersAmy L Krain
New York University Child Study Center, New York University School of Medicine, New York, NY 10016, USA
Biol Psychiatry 63:563-8. 2008..As such, the present study examines the relationship between IU and neural responses to uncertainty in anxious adolescents... - A convergent functional architecture of the insula emerges across imaging modalitiesClare Kelly
Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, New York University Child Study Center, New York, NY 10016, USA
Neuroimage 61:1129-42. 2012..projects.nitrc.org, along with the analytic scripts used to perform the parcellations... - Low frequency oscillations of response time explain parent ratings of inattention and hyperactivity/impulsivityMaria Angeles Mairena
Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, NYU Child Study Center, New York, NY 10016, USA
Eur Child Adolesc Psychiatry 21:101-9. 2012..Results suggest that frequency analyses are a suitable methodology to link behavioral responses to putative underlying physiological processes... - Brain gray matter deficits at 33-year follow-up in adults with attention-deficit/hyperactivity disorder established in childhoodErika Proal
Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, Child Study Center, New York University Langone School of Medicine, USA
Arch Gen Psychiatry 68:1122-34. 2011..We present, to our knowledge, the first prospective study combining cortical thickness and voxel-based morphometry in adults diagnosed as having ADHD in childhood... - Dimensional brain-behavior relationships in children with attention-deficit/hyperactivity disorderCamille Chabernaud
Phyllis Green and Randolph Cōwen Institute for Pediatric Neuroscience at the New York University Child Study Center, Langone Medical Center, New York, New York, USA
Biol Psychiatry 71:434-42. 2012..Additionally, we examined whether dimensional brain-behavior relationships are modified by the presence of a categorically defined illness, attention-deficit/hyperactivity disorder (ADHD)... - Reading networks at restMaki S Koyama
Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, New York University Child Study Center, New York, NY 10016, USA
Cereb Cortex 20:2549-59. 2010..In conclusion, the current study supports the utility of resting-state fMRI for investigating reading networks and has direct relevance for the understanding of reading disorders such as dyslexia... - Competition between functional brain networks mediates behavioral variabilityA M Clare Kelly
The Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, NYU Child Study Center, New York, NY 10016, USA
Neuroimage 39:527-37. 2008..We discuss the implications of these findings for our understanding of the behavioral significance of spontaneous brain activity, in both healthy and clinical populations... - Mapping the functional connectivity of anterior cingulate cortexDaniel S Margulies
The Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, NYU Child Study Center, 215 Lexington Avenue, 14th Floor, New York, NY 10016, USA
Neuroimage 37:579-88. 2007..We discuss the implications of our work for understanding ACC function and potential applications to clinical populations... - Neural and behavioral correlates of expectancy violations in attention-deficit hyperactivity disorderSarah Durston
Sackler Institute for Developmental Psychobiology, Weill Medical College of Cornell University, New York, USA
J Child Psychol Psychiatry 48:881-9. 2007..Therefore, we hypothesized that the ability to predict the occurrence of frequent events would be compromised in ADHD, as well as the ability to adapt behavior when expectancy was violated... - Characterizing variation in the functional connectome: promise and pitfallsClare Kelly
Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, New York University Child Study Center, New York, NY 10016, USA
Trends Cogn Sci 16:181-8. 2012.... - Default mode network abnormalities in idiopathic generalized epilepsyMegan L McGill
NYU Comprehensive Epilepsy Center, New York University School of Medicine, New York, NY, USA
Epilepsy Behav 23:353-9. 2012..The observed pattern of disruption provides evidence for integration- and segregation-type network abnormalities and supports aberrant network organization among people with IGE... - Varieties of attention-deficit/hyperactivity disorder-related intra-individual variabilityF Xavier Castellanos
Institute for Pediatric Neuroscience, New York University, Child Study Center, NYU School of Medicine, New York, New York 10016, USA
Biol Psychiatry 57:1416-23. 2005..These results highlight the importance of retaining time-series data and quantitatively examining intra-subject measures of variability as a putative endophenotype for ADHD... - Differential development of human brain white matter tractsDavide Imperati
Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, Child Study Center, Langone Medical Center, New York University, New York City, New York, United States of America
PLoS ONE 6:e23437. 2011..Our findings demonstrate that data-driven analytic techniques may be fruitfully applied to extant diffusion tensor imaging datasets in normative and neuropsychiatric samples... - The extrinsic and intrinsic functional architectures of the human brain are not equivalentMaarten Mennes
Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, NYU Child Study Center, New York, NY 10016, USA
Cereb Cortex 23:223-9. 2013..Appreciating the full repertoire of dynamic neural responses will continue to require task-based functional magnetic resonance imaging approaches... - Resting state functional connectivity correlates of inhibitory control in children with attention-deficit/hyperactivity disorderMaarten Mennes
Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, NYU Langone School of Medicine, NYU Child Study Center New York, NY, USA
Front Psychiatry 2:83. 2011..Our results demonstrate the utility of RSFC approaches for assessing brain/behavior relationships, and for identifying pathology-related differences in the contributions of neural circuits to cognition and behavior... - Large-scale brain systems in ADHD: beyond the prefrontal-striatal modelF Xavier Castellanos
Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, Child Study Center, NYU Langone School of Medicine, New York, NY, USA
Trends Cogn Sci 16:17-26. 2012.... - Characterizing cognition in ADHD: beyond executive dysfunctionF Xavier Castellanos
Institute for Pediatric Neuroscience, NYU Child Study Center, 215 Lexington Avenue, New York, NY 10016, USA
Trends Cogn Sci 10:117-23. 2006..Such a reconceptualization provides a means to transcend the limits of current models of executive dysfunction in ADHD and suggests a plan for future research on cognition grounded in neurophysiological and developmental considerations... - Uncovering putative neural markers of risk avoidanceAmy Krain Roy
Department of Psychology, City University of New York, Brooklyn, NY 11210, USA
Neuropsychologia 49:937-44. 2011..quot; Further, they underline the need to extend neuroimaging research on risk avoidance, and associated anxiety disorders, to posterior cortical regions... - A meta-analysis of neuropsychological functioning in patients with early onset schizophrenia and pediatric bipolar disorderRebeca Garcia Nieto
Child Study Center, New York University Langone Medical Center, New York, NY, USA
J Clin Child Adolesc Psychol 40:266-80. 2011..Qualitative similarities between the neuropsychological profiles produced by these groups of patients might represent a "continuum of psychosis" or reflect some degree of genetic biological overlap... - Distinct neural mechanisms of risk and ambiguity: a meta-analysis of decision-makingAmy L Krain
New York University Child Study Center, New York University School of Medicine, 215 Lexington Avenue, New York, NY 10016, USA
Neuroimage 32:477-84. 2006..These findings provide evidence for the dissociation of neural circuits underlying risky and ambiguous decision-making, reflecting differential involvement of affective "hot" and cognitive "cool" processes... - Testing tic suppression: comparing the effects of dexmethylphenidate to no medication in children and adolescents with attention-deficit/hyperactivity disorder and Tourette's disorderGholson J Lyon
Department of Child and Adolescent Psychiatry, New York University Child Study Center, New York, New York 10016, USA
J Child Adolesc Psychopharmacol 20:283-9. 2010..The primary hypothesis is that dMPH will improve behaviorally reinforced tic suppression in a standard tic suppression paradigm (TSP)... - Proceed, with caution: SPECT cerebral blood flow studies of children and adolescents with attention deficit hyperactivity disorderF Xavier Castellanos
NYU Child Study Center, New York, New York 10016, USA
J Nucl Med 43:1630-3. 2002 - [Functional cerebral activity in a state of rest: connectivity networks]Erika Proal
Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, Child Study Center, NYU School of Medicine, 215 Lexington Ave, New York, NY 10016, USA
Rev Neurol 52:S3-10. 2011..nitrc.org/projects/srsn)... - Neuroimaging of attention-deficit/hyperactivity disorder: current neuroscience-informed perspectives for cliniciansSamuele Cortese
Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, Child Study Center of the NYU Langone Medical Center, One Park Avenue, 8th Floor, New York, NY 10016, USA
Curr Psychiatry Rep 14:568-78. 2012..Although novel analytical techniques are likely to accelerate the pace of translational applications, at the present we advise caution regarding inappropriate commercial misuse of imaging techniques in ADHD... - Functional neuroimaging of social cognition in pervasive developmental disorders: a brief reviewAdriana Di Martino
New York University Child Study Center, 577 First Avenue, New York, NY 10016, USA
Ann N Y Acad Sci 1008:256-60. 2003..Future studies should extend these important initial results to younger and more severely affected subjects... - Brain development and ADHDAmy L Krain
Institute for Pediatric Neuroscience, NYU Child Study Center, 215 Lexington Avenue, New York, NY 10016, USA
Clin Psychol Rev 26:433-44. 2006..Differences in gray and white matter have also been examined. The ultimate goal of this research is to determine the underlying neurophysiology of ADHD and how specific phenotypes may be related to alterations in brain structure... - Functional MRI in pediatric neurobehavioral disordersMichael Seyffert
Institute for Pediatric Neuroscience, New York University Child Study Center, New York New York 10016, USA
Int Rev Neurobiol 67:239-84. 2005 - [Towards an understanding of the molecular mechanisms underlying the pharmacological treatments of attention deficit hyperactivity disorder]F Xavier Castellanos
Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, Child Study Center, NYU School of Medicine, 215 Lexington Ave, New York, NY 10016, USA
Rev Neurol 52:S155-60. 2011.... - Neuroscience of attention-deficit/hyperactivity disorder: the search for endophenotypesF Xavier Castellanos
New York University Child Study Center, 577 First Avenue, CSC 204, New York, New York 10016-6404, USA
Nat Rev Neurosci 3:617-28. 2002 - Longitudinal mapping of cortical thickness and clinical outcome in children and adolescents with attention-deficit/hyperactivity disorderPhilip Shaw
Child Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892 1500, USA
Arch Gen Psychiatry 63:540-9. 2006..Data from a previous prospective study of lobar volumes in children with attention-deficit/hyperactivity disorder (ADHD) are reexamined using a measure of cortical thickness... - Neurologic examination abnormalities in children with bipolar disorder or attention-deficit/hyperactivity disorderDaniel P Dickstein
National Institute of Mental Health, Pediatrics and Developmental Neuropsychiatry Branch, 10 Center Drive MSC 1255, Building 10 Room 4N208, Bethesda MD 20892 1255, USA
Biol Psychiatry 58:517-24. 2005..To move beyond diagnosis toward unique pathophysiology, we evaluated both ADHD and BPD children for neurologic examination abnormalities (NEAs) in comparison with normal control (NC) children... - Shifting-related brain magnetic activity in attention-deficit/hyperactivity disorderFernando Mulas
Valencian Institute of Pediatric Neurology, Valencia, Spain
Biol Psychiatry 59:373-9. 2006..CONCLUSIONS: These preliminary data support theories of frontal dysfunction in ADHD but also suggest that deficits in higher-level functions might be secondary to disruptions in earlier limbic processes... - Attention-deficit/hyperactivity disorder and comorbid disruptive behavior disorders: evidence of pleiotropy and new susceptibility lociMahim Jain
Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892 3717, USA
Biol Psychiatry 61:1329-39. 2007..Attention-deficit/hyperactivity disorder (ADHD) comorbid with oppositional defiant disorder (ODD) or conduct disorder (CD) and substance abuse/dependence seems to represent a specific subset within the phenotypic ADHD spectrum... - Latent class subtyping of attention-deficit/hyperactivity disorder and comorbid conditionsMaria T Acosta
National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892 3717, USA
J Am Acad Child Adolesc Psychiatry 47:797-807. 2008..The aim of this study was to perform LCA in a sample of 1,010 individuals from a nationwide recruitment of unilineal nuclear families with at least one child with ADHD and another child either affected or clearly unaffected... - Cerebellar neurotransmission in attention-deficit/hyperactivity disorder: does dopamine neurotransmission occur in the cerebellar vermis?Paul E A Glaser
Department of Psychiatry, University of Kentucky Chandler Medical Center, Lexington, 40536, USA
J Neurosci Methods 151:62-7. 2006..The presence of DAT may therefore allow for enhanced regulation of NE and not regulation of released DA... - Molecular genetic studies of ADHD: 1991 to 2004Aaron J Bobb
Child Psychiatry Branch, NIMH, NIH, 10 Center Drive, Bethesda, MD 20892, USA
Am J Med Genet B Neuropsychiatr Genet 132:109-25. 2005..All candidate gene approaches continue to face the problem of relatively low power, given modest odds ratios for even the best replicated genes... - The ipsilateral silent period in boys with attention-deficit/hyperactivity disorderMarjorie A Garvey
Pediatric Movement Disorders Unit, Human Motor Control Section, MNB, NINDS, National Institutes of Health, Bethesda, MD 20892, USA
Clin Neurophysiol 116:1889-96. 2005..Characterize maturation of transcallosal inhibition (ipsilateral silent period [iSP]) in attention deficit/hyperactivity disorder (ADHD) using transcranial magnetic stimulation (TMS)... - Etiologic subtypes of attention-deficit/hyperactivity disorder: brain imaging, molecular genetic and environmental factors and the dopamine hypothesisJames M Swanson
Department of Pediatrics, University of California, Irvine, CA 92612, USA
Neuropsychol Rev 17:39-59. 2007.... - Attention-deficit/hyperactivity disorder in a population isolate: linkage to loci at 4q13.2, 5q33.3, 11q22, and 17p11Mauricio Arcos-Burgos
National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892-3717, USA
Am J Hum Genet 75:998-1014. 2004..The concordance between results from different analytical methods of linkage and the replication of data between two independent studies suggest that these loci truly harbor ADHD susceptibility genes... - Polymorphisms of the dopamine D4 receptor, clinical outcome, and cortical structure in attention-deficit/hyperactivity disorderPhilip Shaw
Child Psychiatry Branch, Room 3N202, Bldg 10, Center Drive, National Institute of Mental Health, Bethesda, MD 20892, USA
Arch Gen Psychiatry 64:921-31. 2007..Attention-deficit/hyperactivity disorder (ADHD) is one of the most heritable neuropsychiatric disorders, and a polymorphism within the dopamine D4 receptor (DRD4) gene has been frequently implicated in its pathogenesis... - Anatomic brain abnormalities in monozygotic twins discordant for attention deficit hyperactivity disorderF Xavier Castellanos
Child Psychiatry Branch, National Institute of Mental Health NIH, Bethesda, MD, USA
Am J Psychiatry 160:1693-6. 2003..To examine brain-behavior relationships in attention deficit hyperactivity disorder (ADHD), the authors obtained magnetic resonance imaging (MRI) scans of monozygotic twins discordant for ADHD... - Monozygotic twins discordant for attention-deficit/hyperactivity disorder: ascertainment and clinical characteristicsWendy S Sharp
Child Psychology Branch of the NIMH, USA
J Am Acad Child Adolesc Psychiatry 42:93-7. 2003..Despite these differences, affected twins were phenotypically comparable with affected singletons. Thus MZ twins discordant for ADHD, while rare, can inform research on the etiology and pathophysiology of this disorder... - Cytogenetic abnormalities in attention-deficit/hyperactivity disorderTheresa M Bastain
Child Psychiatry Branch of the NIMH, USA
J Am Acad Child Adolesc Psychiatry 41:806-10. 2002.... - Developmental trajectories of brain volume abnormalities in children and adolescents with attention-deficit/hyperactivity disorderF Xavier Castellanos
Child Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA
JAMA 288:1740-8. 2002..Various anatomic brain abnormalities have been reported for attention-deficit/hyperactivity disorder (ADHD), with varying methods, small samples, cross-sectional designs, and without accounting for stimulant drug exposure... - Spontaneous attentional fluctuations in impaired states and pathological conditions: a neurobiological hypothesisEdmund J S Sonuga-Barke
Developmental Brain and Behaviour Unit, School of Psychology, University of Southampton, Southampton, UK
Neurosci Biobehav Rev 31:977-86. 2007..Finally, we explore the putative role of default-mode interference as a cause of performance variability in attention deficit/hyperactivity disorder... - Attention-deficit/hyperactivity disorder and comorbidities in 18 Paisa Colombian multigenerational familiesJuan D Palacio
Neurosciences Group, University of Antioquia, , Colombia
J Am Acad Child Adolesc Psychiatry 43:1506-15. 2004..This pattern of comorbidity, as well as the large dense pedigrees of the sample, suggests that it will be particularly useful for molecular genetic studies that are currently under way... - Support for association between ADHD and two candidate genes: NET1 and DRD1Aaron J Bobb
Child Psychiatry Branch, NIMH, NIH, Bethesda, Maryland 20892 1600, USA
Am J Med Genet B Neuropsychiatr Genet 134:67-72. 2005..Because family-based and case-control methods gave divergent results, both should be used in genetic studies of ADHD... - Temporal and probabilistic discounting of rewards in children and adolescents: effects of age and ADHD symptomsAnouk Scheres
Psychology Department, University of Arizona, Tucson, 85721, USA
Neuropsychologia 44:2092-103. 2006..The decrease in TD as observed in adolescents compared to children may be related to developmental changes in the (dorsolateral) prefrontal cortex. Future research needs to investigate these possibilities...