J L Carson

Summary

Affiliation: New Jersey
Country: USA

Publications

  1. ncbi request reprint Transfusion triggers: how low can we go?
    J L Carson
    Department of Medicine, University of Medicine and Dentistry of New Jersey, New Brunswick, USA
    Vox Sang 87:218-21. 2004
  2. pmc Outpatient red blood cell transfusion payments among patients on chronic dialysis
    Matthew Gitlin
    Amgen, Inc, One Amgen Center Drive, Thousand Oaks, CA, USA
    BMC Nephrol 13:145. 2012
  3. pmc Liberal versus restrictive transfusion thresholds for patients with symptomatic coronary artery disease
    Jeffrey L Carson
    Division of General Internal Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, NJ, USA
    Am Heart J 165:964-971.e1. 2013
  4. doi request reprint Outcomes using lower vs higher hemoglobin thresholds for red blood cell transfusion
    Jeffrey L Carson
    Division of General Internal Medicine, UMDNJ Robert Wood Johnson Medical School, 125 Paterson St, New Brunswick, NJ 08903, USA
    JAMA 309:83-4. 2013
  5. doi request reprint Red blood cell transfusion: a clinical practice guideline from the AABB*
    Jeffrey L Carson
    MD, Division of General Internal Medicine, UMDNJ Robert Wood Johnson Medical School, 125 Paterson Street, New Brunswick, NJ 08903, USA
    Ann Intern Med 157:49-58. 2012
  6. doi request reprint Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion
    Jeffrey L Carson
    Division of General Internal Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA
    Cochrane Database Syst Rev 4:CD002042. 2012
  7. doi request reprint Risk of anemia and transfusion triggers: implications for bloodless care
    Jeffrey L Carson
    Division of General Internal Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903, USA
    Surg Infect (Larchmt) 6:S17-21. 2005
  8. ncbi request reprint Mortality and morbidity in patients with very low postoperative Hb levels who decline blood transfusion
    Jeffrey L Carson
    Department of Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, USA
    Transfusion 42:812-8. 2002
  9. ncbi request reprint Transfusion trigger trial for functional outcomes in cardiovascular patients undergoing surgical hip fracture repair (FOCUS)
    Jeffrey L Carson
    Division of General Internal Medicine, Department of Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903, USA
    Transfusion 46:2192-206. 2006
  10. ncbi request reprint RBC transfusion triggers: the evidence
    J L Carson
    Division of General Internal Medicine, UMDNJ Robert Wood Johnson Medical School, 125 Paterson St, Suite 5100, New Brunswick, NJ 08903 0019, USA
    Dev Biol (Basel) 120:201. 2005

Research Grants

  1. FOCUS
    JEFFREY CARSON; Fiscal Year: 2007

Detail Information

Publications52

  1. ncbi request reprint Transfusion triggers: how low can we go?
    J L Carson
    Department of Medicine, University of Medicine and Dentistry of New Jersey, New Brunswick, USA
    Vox Sang 87:218-21. 2004
  2. pmc Outpatient red blood cell transfusion payments among patients on chronic dialysis
    Matthew Gitlin
    Amgen, Inc, One Amgen Center Drive, Thousand Oaks, CA, USA
    BMC Nephrol 13:145. 2012
    ..Our objective was to examine the economic burden for payers when chronic dialysis patients receive outpatient RBC transfusions...
  3. pmc Liberal versus restrictive transfusion thresholds for patients with symptomatic coronary artery disease
    Jeffrey L Carson
    Division of General Internal Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, NJ, USA
    Am Heart J 165:964-971.e1. 2013
    ..Prior trials suggest it is safe to defer transfusion at hemoglobin levels above 7 to 8 g/dL in most patients. Patients with acute coronary syndrome may benefit from higher hemoglobin levels...
  4. doi request reprint Outcomes using lower vs higher hemoglobin thresholds for red blood cell transfusion
    Jeffrey L Carson
    Division of General Internal Medicine, UMDNJ Robert Wood Johnson Medical School, 125 Paterson St, New Brunswick, NJ 08903, USA
    JAMA 309:83-4. 2013
    ....
  5. doi request reprint Red blood cell transfusion: a clinical practice guideline from the AABB*
    Jeffrey L Carson
    MD, Division of General Internal Medicine, UMDNJ Robert Wood Johnson Medical School, 125 Paterson Street, New Brunswick, NJ 08903, USA
    Ann Intern Med 157:49-58. 2012
    ....
  6. doi request reprint Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion
    Jeffrey L Carson
    Division of General Internal Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA
    Cochrane Database Syst Rev 4:CD002042. 2012
    ..The purpose of this review is to compare clinical outcomes in patients randomised to restrictive versus liberal transfusion thresholds (triggers)...
  7. doi request reprint Risk of anemia and transfusion triggers: implications for bloodless care
    Jeffrey L Carson
    Division of General Internal Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903, USA
    Surg Infect (Larchmt) 6:S17-21. 2005
    ..Blood transfusion is a widely used treatment that is expensive and carries a small degree of risk. The level of anemia that patients tolerate and the indications for blood transfusion are controversial...
  8. ncbi request reprint Mortality and morbidity in patients with very low postoperative Hb levels who decline blood transfusion
    Jeffrey L Carson
    Department of Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, USA
    Transfusion 42:812-8. 2002
    ..Guidelines for allogeneic transfusion emphasize minimizing use to avoid transmission of serious illness. However, there is little information on the risks associated from withholding transfusion...
  9. ncbi request reprint Transfusion trigger trial for functional outcomes in cardiovascular patients undergoing surgical hip fracture repair (FOCUS)
    Jeffrey L Carson
    Division of General Internal Medicine, Department of Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903, USA
    Transfusion 46:2192-206. 2006
  10. ncbi request reprint RBC transfusion triggers: the evidence
    J L Carson
    Division of General Internal Medicine, UMDNJ Robert Wood Johnson Medical School, 125 Paterson St, Suite 5100, New Brunswick, NJ 08903 0019, USA
    Dev Biol (Basel) 120:201. 2005
  11. ncbi request reprint Anemia and postoperative rehabilitation
    Jeffrey L Carson
    Division of General Internal Medicine, Department of Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903, USA
    Can J Anaesth 50:S60-4. 2003
    ..It is likely that higher blood counts will result in a more active participation in rehabilitation and greater functional independence. How high the hemoglobin levels need to be awaits further study...
  12. pmc Liberal or restrictive transfusion in high-risk patients after hip surgery
    Jeffrey L Carson
    Division of General Internal Medicine, Department of Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA
    N Engl J Med 365:2453-62. 2011
    ..We conducted a randomized trial to determine whether a higher threshold for blood transfusion would improve recovery in patients who had undergone surgery for hip fracture...
  13. ncbi request reprint Diabetes mellitus increases short-term mortality and morbidity in patients undergoing coronary artery bypass graft surgery
    Jeffrey L Carson
    Division of General Internal Medicine, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick, New Jersey 08093, USA
    J Am Coll Cardiol 40:418-23. 2002
    ..The aim of this study was to determine the impact of diabetes mellitus (DM) on short-term mortality and morbidity in patients undergoing coronary artery bypass surgery (CABG)...
  14. ncbi request reprint Perioperative blood transfusion and postoperative mortality
    J L Carson
    Department of Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick 08903, USA
    JAMA 279:199-205. 1998
    ..The risks of blood transfusion have been studied extensively but the benefits and the hemoglobin concentration at which patients should receive a transfusion have not...
  15. doi request reprint Iron deficiency and heart disease: ironclad evidence?
    Jeffrey L Carson
    Division of General Internal Medicine, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA
    Hematology Am Soc Hematol Educ Program 2010:348-50. 2010
    ..Many questions remain to be answered to understand the role of iron therapy in patients with congestive heart failure...
  16. ncbi request reprint Risk of bacterial infection associated with allogeneic blood transfusion among patients undergoing hip fracture repair
    J L Carson
    Department of Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick 08903, USA
    Transfusion 39:694-700. 1999
    ..An increased risk of bacterial infection would represent the most important risk of allogeneic transfusion, because viral disease transmission has become so rare...
  17. ncbi request reprint Cigarette yield and the risk of myocardial infarction in smokers
    William H Sauer
    Department of Medicine, Cardiovascular Division, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Arch Intern Med 162:300-6. 2002
    ..Although cigarette smoking is a major risk factor for acute myocardial infarction (MI), cigarette tar yield has not been clearly demonstrated to affect MI risk...
  18. doi request reprint Infectious complications after elective vascular surgical procedures
    Todd R Vogel
    Division of Vascular Surgery, The Surgical Outcomes Research Group, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick, NJ 08903 0019, USA
    J Vasc Surg 51:122-9; discussion 129-30. 2010
    ....
  19. ncbi request reprint Reimbursement denial and reversal by health plans at a university hospital
    Jeffrey D Greenberg
    Division of Rheumatology, Department of Medicine, New York University School of Medicine, New York, USA
    Am J Med 117:629-35. 2004
    ..Denial and downgrading of reimbursement for hospital days are two strategies utilized by health plans to maintain profitability. The goal of this study was to describe patterns of discounted reimbursement at a university hospital...
  20. ncbi request reprint Gender and age disparities for smoking-cessation treatment
    Michael B Steinberg
    University of Medicine and Dentistry of New Jersey, Division of General Internal Medicine, New Brunswick, 08903, USA
    Am J Prev Med 30:405-12. 2006
    ..This study evaluates the frequency and predictors of tobacco-use identification, counseling for tobacco dependence, and the prescription of cessation medications in a nationally representative sample of physician-patient encounters...
  21. pmc Prostate-specific antigen screening and mortality from prostate cancer
    Stephen W Marcella
    Department of Epidemiology, UMDNJ School of Public Health, Piscataway, NJ 08854, USA
    J Gen Intern Med 23:248-53. 2008
    ..There is no available evidence from randomized trials that early detection of prostate cancer improves health outcomes, but the prostate-specific antigen (PSA) test is commonly used to screen men for prostate cancer...
  22. ncbi request reprint Triple-combination pharmacotherapy for medically ill smokers: a randomized trial
    Michael B Steinberg
    Division of General Internal Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903, USA
    Ann Intern Med 150:447-54. 2009
    ..Clinical trial data on the effectiveness of triple-combination pharmacotherapy for tobacco dependence treatment in these high-risk smokers are not available...
  23. pmc Anemia in the preoperative patient
    Manish S Patel
    Department of Medicine, Division of General Internal Medicine, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA
    Med Clin North Am 93:1095-104. 2009
    ..The authors review the evaluation of anemia and evidence regarding perioperative blood transfusions. Recommendations on the treatment of anemia, including perioperative blood transfusions, are outlined...
  24. doi request reprint Lower extremity angioplasty: impact of practitioner specialty and volume on practice patterns and healthcare resource utilization
    Todd R Vogel
    Division of Vascular Surgery, The Surgical Outcomes Research Group, Robert Wood Johnson Medical School, The University of Medicine and Dentistry, New Brunswick, New Jersey 08903 0019, USA
    J Vasc Surg 50:1320-4; discussion 1324-5. 2009
    ..We hypothesized that cardiologists (CRD) and vascular surgeons (VAS) may have different practice patterns, indications for intervention, and hospital resource utilization...
  25. ncbi request reprint Is there an optimal hemoglobin value in the cardiac intensive care unit?
    Ronald S Freudenberger
    Heart Failure and Transplant Cardiology Program, UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA
    Curr Opin Crit Care 9:356-61. 2003
    ..Pulmonary edema may be precipitated by transfusion in patients with left ventricular dysfunction. Large clinical trials are urgently needed to determine optimal transfusion thresholds in patients with cardiovascular disease...
  26. ncbi request reprint Diagnosis of venous thromboembolism: factors determining individual patient probabilities of deep vein thrombosis or pulmonary embolism
    Gabriela S Ferreira
    Division of General Internal Medicine, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, 125 Paterson Street, New Brunswick, NJ 08903, USA
    Curr Hematol Rep 2:423-8. 2003
    ..Techniques to estimate the pretest probability of deep vein thrombosis and pulmonary embolism are described...
  27. ncbi request reprint The cost-effectiveness of autologous transfusion revisited: implications of an increased risk of bacterial infection with allogeneic transfusion
    F A Sonnenberg
    Department of Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick 08903, USA
    Transfusion 39:808-17. 1999
    ..Previous analyses have found autologous transfusion to be very expensive but have not considered avoidance of postoperative bacterial infections as one of its benefits...
  28. ncbi request reprint In search of the transfusion threshold
    Jeffrey L Carson
    Division of General Internal Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA
    Hematology 10:86-8. 2005
  29. ncbi request reprint Anemia and clinical outcomes
    Mercy Kuriyan
    Transfusion Medicine, Department of Pathology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, 125 Patterson Street, Professional Building, 4th Floor, New Brunswick, NJ 08903, USA
    Anesthesiol Clin North America 23:315-25, vii. 2005
    ..Relevant data from animal and human studies, the adaptive mechanisms in anemia, and current views on transfusion triggers are evaluated. Recommendations are provided for the anesthesiologist for transfusion of red blood cells...
  30. ncbi request reprint Evaluation and management of anemia and bleeding disorders in surgical patients
    Barbara Armas-Loughran
    Division of General Internal Medicine, Department of Medicine, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, 125 Patterson Street, Professional Building, 4th Floor, New Brunswick, NJ 08903, USA
    Med Clin North Am 87:229-42. 2003
    ..Finally, some patients may need correction of their bleeding disorder before surgery or careful monitoring in the perioperative period...
  31. ncbi request reprint Physician malpractice: does the past predict the future?
    M I Taragin
    Department of Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick 08903 0019, USA
    J Gen Intern Med 10:550-6. 1995
    ..To assess whether there is a population of physicians who have consistently poor malpractice claims experiences over time...
  32. ncbi request reprint Germline mutations in an intermediate chain dynein cause primary ciliary dyskinesia
    M Zariwala
    Department of Medicine, University of North Carolina at Chapel Hill, USA
    Am J Respir Cell Mol Biol 25:577-83. 2001
    ..Mutations in DNAI1 are causative for PCD with ODA defects, and are likely the genetic origin of clinical disease in some PCD patients with ultrastructural defects in the ODA...
  33. pmc Postoperative sepsis in the United States
    Todd R Vogel
    The Surgical Outcomes Research Group, Department of Surgery, Robert Wood Johnson Medical School, New Brunswick, NJ, USA
    Ann Surg 252:1065-71. 2010
    ..To evaluate the incidence of postoperative sepsis after elective procedures, to define surgical procedures with the greatest risk for developing sepsis, and to evaluate patient and hospital confounders...
  34. ncbi request reprint The effects of time-to-surgery on mortality and morbidity in patients following hip fracture
    Julia P Grimes
    Division of General Internal Medicine, University of Medicine and Dentistry, Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903, USA
    Am J Med 112:702-9. 2002
    ..There is a perception that the standard of care is to repair hip fractures surgically within 24 hours of hospitalization. However, it is unclear whether this reduces mortality or morbidity...
  35. ncbi request reprint Transfusion triggers: a systematic review of the literature
    Jeffrey L Carson
    Division of General Internal Medicine, Department of Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA
    Transfus Med Rev 16:187-99. 2002
    ..In countries with inadequate screening of donor blood, the data may constitute a stronger basis for avoiding transfusion with allogeneic RBCs...
  36. ncbi request reprint Blood transfusion risks in the intensive care unit
    Mercy Kuriyan
    Transfusion Medicine Services, Department of Pathology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, 232 MEB, One Robert Wood Place, New Brunswick, NJ 08903, USA
    Crit Care Clin 20:237-53, ix. 2004
    ..Diagnosis of the type of transfusion reaction by laboratory tests is detailed. Finally, the article discusses the dangers of human error with possible strategies to combat this problem using new technologies...
  37. ncbi request reprint Red blood cell transfusion in clinical practice
    Harvey G Klein
    Department of Transfusion Medicine, National Institutes of Health, Bethesda, Maryland 20892, USA
    Lancet 370:415-26. 2007
    ..Despite serious immunological and non-immunological complications, RBC transfusion holds a therapeutic index that exceeds that of many common medications...
  38. ncbi request reprint Blood transfusion--when is more really less?
    Howard L Corwin
    N Engl J Med 356:1667-9. 2007
  39. ncbi request reprint Higher Hb level is associated with better early functional recovery after hip fracture repair
    Valerie A Lawrence
    Veterans Evidence Based Research Dissemination and Implementation Center VERDICT, South Texas Veterans Health Care System, San Antonio, Texas, USA
    Transfusion 43:1717-22. 2003
    ..One possible reason to transfuse is to improve functional recovery after major surgery. However, the data linking improved function with higher Hb concentration are limited...
  40. ncbi request reprint Risk factors for hospital-acquired incontinence in elderly female hip fracture patients
    Mary H Palmer
    School of Nursing, University of North Carolina, Chapel Hill, NC 27599, USA
    J Gerontol A Biol Sci Med Sci 57:M672-7. 2002
    ..The study was a secondary analysis of data abstracted from medical records in hospitals in Pennsylvania, Texas, New Jersey, and Virginia...
  41. ncbi request reprint Medical complications and outcomes after hip fracture repair
    Valerie A Lawrence
    Division of General Medicine, Audie L Murphy Division, South Texas Veterans Health Care System, San Antonio, TX, USA
    Arch Intern Med 162:2053-7. 2002
    ..Most evidence guiding perioperative medical risk management of patients undergoing hip fracture repair focuses on cardiac and thromboembolic risk. Little is known of the relative clinical importance of other complications...
  42. ncbi request reprint Will we ever know if leukoreduction of red blood cells should be performed?
    Jeffrey L Carson
    Can J Anaesth 51:407-10. 2004
  43. ncbi request reprint Detection, evaluation, and management of anemia in the elective surgical patient
    Lawrence T Goodnough
    Department of Pathology, Stanford University Medical Center, 300 Pasteur Drive H 1402, Stanford, CA 94305 5626, USA
    Anesth Analg 101:1858-61. 2005
    ....
  44. ncbi request reprint Blood transfusion: less is more?
    Jeffrey L Carson
    Crit Care Med 31:2409-10. 2003
  45. ncbi request reprint Indications for early red blood cell transfusion
    Richard P Dutton
    University of Maryland School of Medicine, and Division of Trauma Anesthesiology, R Adams Cowley Shock Trauma Center, University of Maryland Medical System, USA
    J Trauma 60:S35-40. 2006
  46. ncbi request reprint Clinical prediction rules for the diagnosis of pulmonary embolism
    Gabriela Ferreira
    Am J Med 113:337-8. 2002
  47. ncbi request reprint Parenteral ketorolac and risk of myocardial infarction
    Stephen E Kimmel
    Center for Clinical Epidemiology and Biostatistics and Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Pharmacoepidemiol Drug Saf 11:113-9. 2002
    ..To examine the effects of ketorolac, a non-aspirin non-steroidal anti-inflammatory drug (NANSAID) with antiplatelet properties, on the risk of in-hospital myocardial infarction (MI)...
  48. ncbi request reprint The life-sustaining capacity of human polymerized hemoglobin when red cells might be unavailable
    Steven A Gould
    Northfield Laboratories Inc, Evanston, IL, USA
    J Am Coll Surg 195:445-52; discussion 452-5. 2002
    ..PolyHeme should be particularly useful when red cells may be temporarily unavailable. This article assesses survival at life-threatening RBC hemoglobin concentration ([Hb]) in massively bleeding patients who do not receive red cells...
  49. ncbi request reprint Should patients in intensive care units receive erythropoietin?
    Jeffrey L Carson
    JAMA 288:2884-6. 2002
  50. ncbi request reprint Subcutaneous unfractionated heparin vs low-molecular-weight heparin for acute thromboembolic disease: issues of efficacy and cost
    Jeffrey L Carson
    JAMA 296:991-3. 2006
  51. ncbi request reprint Risk factors for pressure ulcers among elderly hip fracture patients
    Mona Baumgarten
    Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    Wound Repair Regen 11:96-103. 2003
    ....
  52. ncbi request reprint Bad bad blood?
    Jeffrey L Carson
    Crit Care Med 36:2707-8. 2008

Research Grants1

  1. FOCUS
    JEFFREY CARSON; Fiscal Year: 2007
    ..abstract_text> ..