Research Topics
| J L CarsonSummaryAffiliation: New Jersey Country: USA Publications
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Publications
Transfusion triggers: how low can we go?J L Carson
Department of Medicine, University of Medicine and Dentistry of New Jersey, New Brunswick, USA
Vox Sang 87:218-21. 2004
Outcomes using lower vs higher hemoglobin thresholds for red blood cell transfusionJeffrey L Carson
Division of General Internal Medicine, UMDNJ Robert Wood Johnson Medical School, 125 Paterson St, New Brunswick, NJ 08903, USA
JAMA 309:83-4. 2013....- Red blood cell transfusion: a clinical practice guideline from the AABB*Jeffrey L Carson
MD, Division of General Internal Medicine, UMDNJ Robert Wood Johnson Medical School, 125 Paterson Street, New Brunswick, NJ 08903, USA
Ann Intern Med 157:49-58. 2012..RECOMMENDATION 4: The AABB suggests that transfusion decisions be influenced by symptoms as well as hemoglobin concentration (Grade: weak recommendation; low-quality evidence)... - Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusionJeffrey L Carson
Division of General Internal Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA
Cochrane Database Syst Rev 4:CD002042. 2012..The purpose of this review is to compare clinical outcomes in patients randomised to restrictive versus liberal transfusion thresholds (triggers)... - Anemia and postoperative rehabilitationJeffrey L Carson
Division of General Internal Medicine, Department of Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903, USA
Can J Anaesth 50:S60-4. 2003..It is likely that higher blood counts will result in a more active participation in rehabilitation and greater functional independence. How high the hemoglobin levels need to be awaits further study... - Transfusion trigger trial for functional outcomes in cardiovascular patients undergoing surgical hip fracture repair (FOCUS)Jeffrey L Carson
Division of General Internal Medicine, Department of Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903, USA
Transfusion 46:2192-206. 2006 - Mortality and morbidity in patients with very low postoperative Hb levels who decline blood transfusionJeffrey L Carson
Department of Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, USA
Transfusion 42:812-8. 2002..Guidelines for allogeneic transfusion emphasize minimizing use to avoid transmission of serious illness. However, there is little information on the risks associated from withholding transfusion... - Risk of anemia and transfusion triggers: implications for bloodless careJeffrey L Carson
Division of General Internal Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903, USA
Surg Infect (Larchmt) 6:S17-21. 2005..Blood transfusion is a widely used treatment that is expensive and carries a small degree of risk. The level of anemia that patients tolerate and the indications for blood transfusion are controversial... - Diabetes mellitus increases short-term mortality and morbidity in patients undergoing coronary artery bypass graft surgeryJeffrey L Carson
Division of General Internal Medicine, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick, New Jersey 08093, USA
J Am Coll Cardiol 40:418-23. 2002..The aim of this study was to determine the impact of diabetes mellitus (DM) on short-term mortality and morbidity in patients undergoing coronary artery bypass surgery (CABG)... - Iron deficiency and heart disease: ironclad evidence?Jeffrey L Carson
Division of General Internal Medicine, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA
Hematology Am Soc Hematol Educ Program 2010:348-50. 2010..Many questions remain to be answered to understand the role of iron therapy in patients with congestive heart failure... 
Liberal or restrictive transfusion in high-risk patients after hip surgeryJeffrey L Carson
Division of General Internal Medicine, Department of Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA
N Engl J Med 365:2453-62. 2011..We conducted a randomized trial to determine whether a higher threshold for blood transfusion would improve recovery in patients who had undergone surgery for hip fracture...- Risk of bacterial infection associated with allogeneic blood transfusion among patients undergoing hip fracture repairJ L Carson
Department of Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick 08903, USA
Transfusion 39:694-700. 1999..An increased risk of bacterial infection would represent the most important risk of allogeneic transfusion, because viral disease transmission has become so rare... - Perioperative blood transfusion and postoperative mortalityJ L Carson
Department of Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick 08903, USA
JAMA 279:199-205. 1998..The risks of blood transfusion have been studied extensively but the benefits and the hemoglobin concentration at which patients should receive a transfusion have not... - RBC transfusion triggers: the evidenceJ L Carson
Division of General Internal Medicine, UMDNJ-Robert Wood Johnson Medical School, 125 Paterson St, Suite 5100, New Brunswick, NJ 08903-0019, USA
Dev Biol (Basel) 120:201. 2005 - Cigarette yield and the risk of myocardial infarction in smokersWilliam H Sauer
Department of Medicine, Cardiovascular Division, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Arch Intern Med 162:300-6. 2002..001 for the trend). CONCLUSIONS: Smoking higher-yield cigarettes is associated with an increased risk of MI, and there is a dose-response relationship between total tar consumption per day and MI... - Gender and age disparities for smoking-cessation treatmentMichael B Steinberg
University of Medicine and Dentistry of New Jersey, Division of General Internal Medicine, New Brunswick, 08903, USA
Am J Prev Med 30:405-12. 2006..This study evaluates the frequency and predictors of tobacco-use identification, counseling for tobacco dependence, and the prescription of cessation medications in a nationally representative sample of physician-patient encounters... - Reimbursement denial and reversal by health plans at a university hospitalJeffrey D Greenberg
Division of Rheumatology, Department of Medicine, New York University School of Medicine, New York, USA
Am J Med 117:629-35. 2004..More profitable plans had higher denial and discount rates. Evidence-based standards for denials and downgrades are needed to maintain optimal patient care and the fiscal health of hospitals and health plans... - Triple-combination pharmacotherapy for medically ill smokers: a randomized trialMichael B Steinberg
Division of General Internal Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903, USA
Ann Intern Med 150:447-54. 2009..Clinical trial data on the effectiveness of triple-combination pharmacotherapy for tobacco dependence treatment in these high-risk smokers are not available... - Anemia in the preoperative patientManish S Patel
Department of Medicine, Division of General Internal Medicine, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA
Med Clin North Am 93:1095-104. 2009..The authors review the evaluation of anemia and evidence regarding perioperative blood transfusions. Recommendations on the treatment of anemia, including perioperative blood transfusions, are outlined... - Lower extremity angioplasty: impact of practitioner specialty and volume on practice patterns and healthcare resource utilizationTodd R Vogel
Division of Vascular Surgery, The Surgical Outcomes Research Group, Robert Wood Johnson Medical School, The University of Medicine and Dentistry, New Brunswick, New Jersey 08903 0019, USA
J Vasc Surg 50:1320-4; discussion 1324-5. 2009..We hypothesized that cardiologists (CRD) and vascular surgeons (VAS) may have different practice patterns, indications for intervention, and hospital resource utilization... - Prostate-specific antigen screening and mortality from prostate cancerStephen W Marcella
Department of Epidemiology, UMDNJ School of Public Health, Piscataway, NJ 08854, USA
J Gen Intern Med 23:248-53. 2008..There is no available evidence from randomized trials that early detection of prostate cancer improves health outcomes, but the prostate-specific antigen (PSA) test is commonly used to screen men for prostate cancer... - Is there an optimal hemoglobin value in the cardiac intensive care unit?Ronald S Freudenberger
Heart Failure and Transplant Cardiology Program, UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA
Curr Opin Crit Care 9:356-61. 2003..Pulmonary edema may be precipitated by transfusion in patients with left ventricular dysfunction. Large clinical trials are urgently needed to determine optimal transfusion thresholds in patients with cardiovascular disease... - Infectious complications after elective vascular surgical proceduresTodd R Vogel
Division of Vascular Surgery, The Surgical Outcomes Research Group, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick, NJ 08903 0019, USA
J Vasc Surg 51:122-9; discussion 129-30. 2010.... - Diagnosis of venous thromboembolism: factors determining individual patient probabilities of deep vein thrombosis or pulmonary embolismGabriela S Ferreira
Division of General Internal Medicine, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, 125 Paterson Street, New Brunswick, NJ 08903, USA
Curr Hematol Rep 2:423-8. 2003..Techniques to estimate the pretest probability of deep vein thrombosis and pulmonary embolism are described... - The cost-effectiveness of autologous transfusion revisited: implications of an increased risk of bacterial infection with allogeneic transfusionF A Sonnenberg
Department of Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick 08903, USA
Transfusion 39:808-17. 1999..Previous analyses have found autologous transfusion to be very expensive but have not considered avoidance of postoperative bacterial infections as one of its benefits... - In search of the transfusion thresholdJeffrey L Carson
Division of General Internal Medicine, UMDNJ-Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA
Hematology 10:86-8. 2005 - Anemia and clinical outcomesMercy Kuriyan
Transfusion Medicine, Department of Pathology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, 125 Patterson Street, Professional Building, 4th Floor, New Brunswick, NJ 08903, USA
Anesthesiol Clin North America 23:315-25, vii. 2005..Relevant data from animal and human studies, the adaptive mechanisms in anemia, and current views on transfusion triggers are evaluated. Recommendations are provided for the anesthesiologist for transfusion of red blood cells... - Evaluation and management of anemia and bleeding disorders in surgical patientsBarbara Armas-Loughran
Division of General Internal Medicine, Department of Medicine, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, 125 Patterson Street, Professional Building, 4th Floor, New Brunswick, NJ 08903, USA
Med Clin North Am 87:229-42. 2003..Finally, some patients may need correction of their bleeding disorder before surgery or careful monitoring in the perioperative period... - Germline mutations in an intermediate chain dynein cause primary ciliary dyskinesiaM Zariwala
Department of Medicine, University of North Carolina at Chapel Hill, USA
Am J Respir Cell Mol Biol 25:577-83. 2001..Mutations in DNAI1 are causative for PCD with ODA defects, and are likely the genetic origin of clinical disease in some PCD patients with ultrastructural defects in the ODA... - Physician malpractice: does the past predict the future?M I Taragin
Department of Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick 08903 0019, USA
J Gen Intern Med 10:550-6. 1995..To assess whether there is a population of physicians who have consistently poor malpractice claims experiences over time... - Postoperative sepsis in the United StatesTodd R Vogel
The Surgical Outcomes Research Group, Department of Surgery, Robert Wood Johnson Medical School, New Brunswick, NJ, USA
Ann Surg 252:1065-71. 2010..To evaluate the incidence of postoperative sepsis after elective procedures, to define surgical procedures with the greatest risk for developing sepsis, and to evaluate patient and hospital confounders... - The effects of time-to-surgery on mortality and morbidity in patients following hip fractureJulia P Grimes
Division of General Internal Medicine, University of Medicine and Dentistry, Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903, USA
Am J Med 112:702-9. 2002..Other than increasing the risk of decubitus ulcer formation, waiting did not appear to affect patients' outcomes adversely... - Blood transfusion risks in the intensive care unitMercy Kuriyan
Transfusion Medicine Services, Department of Pathology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, 232 MEB, One Robert Wood Place, New Brunswick, NJ 08903, USA
Crit Care Clin 20:237-53, ix. 2004..Diagnosis of the type of transfusion reaction by laboratory tests is detailed. Finally, the article discusses the dangers of human error with possible strategies to combat this problem using new technologies... - Transfusion triggers: a systematic review of the literatureJeffrey L Carson
Division of General Internal Medicine, Department of Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA
Transfus Med Rev 16:187-99. 2002..In countries with inadequate screening of donor blood, the data may constitute a stronger basis for avoiding transfusion with allogeneic RBCs... - Medical complications and outcomes after hip fracture repairValerie A Lawrence
Division of General Medicine, Audie L Murphy Division, South Texas Veterans Health Care System, San Antonio, TX, USA
Arch Intern Med 162:2053-7. 2002..Most evidence guiding perioperative medical risk management of patients undergoing hip fracture repair focuses on cardiac and thromboembolic risk. Little is known of the relative clinical importance of other complications... - Red blood cell transfusion in clinical practiceHarvey G Klein
Department of Transfusion Medicine, National Institutes of Health, Bethesda, Maryland 20892, USA
Lancet 370:415-26. 2007..Despite serious immunological and non-immunological complications, RBC transfusion holds a therapeutic index that exceeds that of many common medications... - Blood transfusion--when is more really less?Howard L Corwin
N Engl J Med 356:1667-9. 2007 - Higher Hb level is associated with better early functional recovery after hip fracture repairValerie A Lawrence
Veterans Evidence Based Research Dissemination and Implementation Center VERDICT, South Texas Veterans Health Care System, San Antonio, Texas, USA
Transfusion 43:1717-22. 2003..One possible reason to transfuse is to improve functional recovery after major surgery. However, the data linking improved function with higher Hb concentration are limited... - Risk factors for hospital-acquired incontinence in elderly female hip fracture patientsMary H Palmer
School of Nursing, University of North Carolina, Chapel Hill, NC 27599, USA
J Gerontol A Biol Sci Med Sci 57:M672-7. 2002..The study was a secondary analysis of data abstracted from medical records in hospitals in Pennsylvania, Texas, New Jersey, and Virginia... - Will we ever know if leukoreduction of red blood cells should be performed?Jeffrey L Carson
Can J Anaesth 51:407-10. 2004 - Clinical prediction rules for the diagnosis of pulmonary embolismGabriela Ferreira
Am J Med 113:337-8. 2002 - Parenteral ketorolac and risk of myocardial infarctionStephen E Kimmel
Center for Clinical Epidemiology and Biostatistics and Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
Pharmacoepidemiol Drug Saf 11:113-9. 2002..To examine the effects of ketorolac, a non-aspirin non-steroidal anti-inflammatory drug (NANSAID) with antiplatelet properties, on the risk of in-hospital myocardial infarction (MI)... - Bad bad blood?Jeffrey L Carson
Crit Care Med 36:2707-8. 2008 - The life-sustaining capacity of human polymerized hemoglobin when red cells might be unavailableSteven A Gould
Northfield Laboratories Inc, Evanston, IL, USA
J Am Coll Surg 195:445-52; discussion 452-5. 2002..PolyHeme should be useful in the early treatment of urgent blood loss and resolve the dilemma of unavailability of red cells... - Risk factors for pressure ulcers among elderly hip fracture patientsMona Baumgarten
Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
Wound Repair Regen 11:96-103. 2003.... - Should patients in intensive care units receive erythropoietin?Jeffrey L Carson
JAMA 288:2884-6. 2002 - Subcutaneous unfractionated heparin vs low-molecular-weight heparin for acute thromboembolic disease: issues of efficacy and costJeffrey L Carson
JAMA 296:991-3. 2006 - Indications for early red blood cell transfusionRichard P Dutton
University of Maryland School of Medicine, and Division of Trauma Anesthesiology, R Adams Cowley Shock Trauma Center, University of Maryland Medical System, USA
J Trauma 60:S35-40. 2006 - Blood transfusion: less is more?Jeffrey L Carson
Crit Care Med 31:2409-10. 2003 - Detection, evaluation, and management of anemia in the elective surgical patientLawrence T Goodnough
Department of Pathology, Stanford University Medical Center, 300 Pasteur Drive H 1402, Stanford, CA 94305 5626, USA
Anesth Analg 101:1858-61. 2005....
Research Grants
- FOCUSJEFFREY CARSON; Fiscal Year: 2007..abstract_text> ..