K D Carr

Summary

Affiliation: New York University School of Medicine
Country: USA

Publications

  1. pmc Food scarcity, neuroadaptations, and the pathogenic potential of dieting in an unnatural ecology: binge eating and drug abuse
    Kenneth D Carr
    Department of Psychiatry, Millhauser Laboratories, New York University School of Medicine, 550 First Ave, New York, NY 10016, USA
    Physiol Behav 104:162-7. 2011
  2. pmc AMPA receptor subunit GluR1 downstream of D-1 dopamine receptor stimulation in nucleus accumbens shell mediates increased drug reward magnitude in food-restricted rats
    K D Carr
    Department of Psychiatry, New York University School of Medicine, New York, NY 10016, USA
    Neuroscience 165:1074-86. 2010
  3. ncbi request reprint Food restriction increases NMDA receptor-mediated calcium-calmodulin kinase II and NMDA receptor/extracellular signal-regulated kinase 1/2-mediated cyclic amp response element-binding protein phosphorylation in nucleus accumbens upon D-1 dopamine receptor
    S L Haberny
    Department of Pharmacology, New York University School of Medicine, NY 10016, USA
    Neuroscience 132:1035-43. 2005
  4. ncbi request reprint Rewarding and locomotor-activating effects of direct dopamine receptor agonists are augmented by chronic food restriction in rats
    K D Carr
    Millhauser Laboratories, Department of Psychiatry, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    Psychopharmacology (Berl) 154:420-8. 2001
  5. ncbi request reprint Chronic food restriction increases D-1 dopamine receptor agonist-induced phosphorylation of extracellular signal-regulated kinase 1/2 and cyclic AMP response element-binding protein in caudate-putamen and nucleus accumbens
    S L Haberny
    Department of Pharmacology, New York University School of Medicine, New York, NY 10016, USA
    Neuroscience 125:289-98. 2004
  6. ncbi request reprint Evidence of increased dopamine receptor signaling in food-restricted rats
    K D Carr
    Department of Psychiatry, Millhauser Laboratories, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    Neuroscience 119:1157-67. 2003
  7. ncbi request reprint Increased site-specific phosphorylation of tyrosine hydroxylase accompanies stimulation of enzymatic activity induced by cessation of dopamine neuronal activity
    J Y Lew
    Department of Psychiatry, New York University Medical Center, New York, New York, USA
    Mol Pharmacol 55:202-9. 1999
  8. ncbi request reprint Effects of chronic ICV leptin infusion on motor-activating effects of D-amphetamine in food-restricted and ad libitum fed rats
    J Hao
    Department of Pharmacology, School of Medicine, New York University, New York, NY 10016, USA
    Physiol Behav 83:377-81. 2004
  9. ncbi request reprint Effects of the D(3) dopamine receptor antagonist, U99194A, on brain stimulation and d-amphetamine reward, motor activity, and c-fos expression in ad libitum fed and food-restricted rats
    K D Carr
    Department of Pharmacology, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    Psychopharmacology (Berl) 163:76-84. 2002
  10. ncbi request reprint Chronic food restriction in rats augments the central rewarding effect of cocaine and the delta1 opioid agonist, DPDPE, but not the delta2 agonist, deltorphin-II
    K D Carr
    Department of Psychiatry, New York University School of Medicine, New York 10016, USA
    Psychopharmacology (Berl) 152:200-7. 2000

Collaborators

Detail Information

Publications17

  1. pmc Food scarcity, neuroadaptations, and the pathogenic potential of dieting in an unnatural ecology: binge eating and drug abuse
    Kenneth D Carr
    Department of Psychiatry, Millhauser Laboratories, New York University School of Medicine, 550 First Ave, New York, NY 10016, USA
    Physiol Behav 104:162-7. 2011
    ..Possible mechanistic underpinnings of increased drug reward magnitude, drug-seeking, and binge intake of sucrose in food-restricted animal subjects are discussed and possible implications for human weight-loss dieting are considered...
  2. pmc AMPA receptor subunit GluR1 downstream of D-1 dopamine receptor stimulation in nucleus accumbens shell mediates increased drug reward magnitude in food-restricted rats
    K D Carr
    Department of Psychiatry, New York University School of Medicine, New York, NY 10016, USA
    Neuroscience 165:1074-86. 2010
    ....
  3. ncbi request reprint Food restriction increases NMDA receptor-mediated calcium-calmodulin kinase II and NMDA receptor/extracellular signal-regulated kinase 1/2-mediated cyclic amp response element-binding protein phosphorylation in nucleus accumbens upon D-1 dopamine receptor
    S L Haberny
    Department of Pharmacology, New York University School of Medicine, NY 10016, USA
    Neuroscience 132:1035-43. 2005
    ..The upregulated cellular responses to D-1 DA agonist challenge may play a role in the augmentation of drug reward and appetitive instrumental learning during periods of food restriction...
  4. ncbi request reprint Rewarding and locomotor-activating effects of direct dopamine receptor agonists are augmented by chronic food restriction in rats
    K D Carr
    Millhauser Laboratories, Department of Psychiatry, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    Psychopharmacology (Berl) 154:420-8. 2001
    ..It is not known whether behavioral effects of selective, direct DA receptor agonists are also subject to the augmenting effect of food restriction...
  5. ncbi request reprint Chronic food restriction increases D-1 dopamine receptor agonist-induced phosphorylation of extracellular signal-regulated kinase 1/2 and cyclic AMP response element-binding protein in caudate-putamen and nucleus accumbens
    S L Haberny
    Department of Pharmacology, New York University School of Medicine, New York, NY 10016, USA
    Neuroscience 125:289-98. 2004
    ..The upregulation of striatal MAP kinase signaling in food-restricted animals may adaptively serve to facilitate associative learning but, at the same time, increase vulnerability to the rewarding and addictive properties of abused drugs...
  6. ncbi request reprint Evidence of increased dopamine receptor signaling in food-restricted rats
    K D Carr
    Department of Psychiatry, Millhauser Laboratories, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    Neuroscience 119:1157-67. 2003
    ..The signaling pathways mediating these augmented responses remain to be fully elucidated...
  7. ncbi request reprint Increased site-specific phosphorylation of tyrosine hydroxylase accompanies stimulation of enzymatic activity induced by cessation of dopamine neuronal activity
    J Y Lew
    Department of Psychiatry, New York University Medical Center, New York, New York, USA
    Mol Pharmacol 55:202-9. 1999
    ..Thus, TH activity seems to be regulated by phosphorylation in both hyper- and hypoactive striatal DA neurons; in the latter case, activation seems to be caused by selective phosphorylation of Ser40...
  8. ncbi request reprint Effects of chronic ICV leptin infusion on motor-activating effects of D-amphetamine in food-restricted and ad libitum fed rats
    J Hao
    Department of Pharmacology, School of Medicine, New York University, New York, NY 10016, USA
    Physiol Behav 83:377-81. 2004
    ....
  9. ncbi request reprint Effects of the D(3) dopamine receptor antagonist, U99194A, on brain stimulation and d-amphetamine reward, motor activity, and c-fos expression in ad libitum fed and food-restricted rats
    K D Carr
    Department of Pharmacology, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
    Psychopharmacology (Berl) 163:76-84. 2002
    ..However, the locations of the D(3) receptors that regulate behavior, and the range of behavioral functions regulated, are not clear...
  10. ncbi request reprint Chronic food restriction in rats augments the central rewarding effect of cocaine and the delta1 opioid agonist, DPDPE, but not the delta2 agonist, deltorphin-II
    K D Carr
    Department of Psychiatry, New York University School of Medicine, New York 10016, USA
    Psychopharmacology (Berl) 152:200-7. 2000
    ..The increased expression of c-fos in nucleus accumbens (NAC) shell, in particular, suggests that food restriction may augment drug reward by modulating dopamine (DA) synaptic function in this area...
  11. ncbi request reprint Effect of chronic food restriction on Fos-like immunoreactivity (FLI) induced in rat brain regions by intraventricular MK-801
    K D Carr
    Millhauser Laboratories, Department of Psychiatry, New York University, School of Medicine, 550 First Avenue, New York, NY 1 0016, USA
    Brain Res 873:283-6. 2000
    ....
  12. ncbi request reprint Hypoinsulinemia may mediate the lowering of self-stimulation thresholds by food restriction and streptozotocin-induced diabetes
    K D Carr
    Millhauser Laboratories, Department of Psychiatry, New York University, School of Medicine, 550 First Avenue, New York, NY, USA
    Brain Res 863:160-8. 2000
    ....
  13. ncbi request reprint Chronic food restriction increases fos-like immunoreactivity (FLI) induced in rat forebrain by intraventricular amphetamine
    K D Carr
    Millhauser Laboratories, Department of Psychiatry, New York University, School of Medicine, New York, NY 10016, USA
    Brain Res 861:88-96. 2000
    ....
  14. ncbi request reprint Differential effects of mu and kappa opioid antagonists on Fos-like immunoreactivity in extended amygdala
    K D Carr
    Millhauser Laboratories, Department of Psychiatry, New York University Medical School, 550 First Avenue, New York, NY 10016, USA
    Brain Res 822:34-42. 1999
    ....
  15. ncbi request reprint Feeding, body weight, and sensitivity to non-ingestive reward stimuli during and after 12-day continuous central infusions of melanocortin receptor ligands
    S Cabeza de Vaca
    Department of Psychiatry, New York University School of Medicine, Millhauser Laboratories, 550 First Avenue, New York, NY 10016, USA
    Peptides 26:2314-21. 2005
    ..However, it is possible that the drive to re-feed and restore body weight following MCR agonist treatment includes neuroadaptations that enhance the incentive effects of drug stimuli...
  16. pmc A food restriction protocol that increases drug reward decreases tropomyosin receptor kinase B in the ventral tegmental area, with no effect on brain-derived neurotrophic factor or tropomyosin receptor kinase B protein levels in dopaminergic forebrain reg
    Y Pan
    Department of Psychiatry, New York University School of Medicine, 550 First Avenue, NY 10016, USA
    Neuroscience 197:330-8. 2011
    ....
  17. ncbi request reprint 5-Hydroxytryptamine(1A) receptor-stimulated [(35)S]GTPgammaS binding in rat brain: absence of regional differences in coupling efficiency
    E Meller
    Millhauser Laboratories, Department of Psychiatry, New York University Medical Center, New York, New York, USA
    J Pharmacol Exp Ther 292:684-91. 2000
    ....